Impact of Pre-existing Type 2 Diabetes Mellitus and Cardiovascular Disease on Healthcare Resource Utilization and Costs in Patients With COVID-19 by Chi Nguyen, Christopher L. Crowe, Effie Kuti, Bonnie Donato, Rachel Djaraher, Leo Seman, Nancy Graeter, Thomas P. Power, Rinku Mehra, Vincent J. Willey

“…**Methods:** A retrospective observational study in COVID-19 patients using data from the Healthcare Integrated Research Database (HIRD®) was conducted. Patients with COVID-19 were identified between March 1, 2020, and May 31, 2021, and followed from first diagnosis or positive lab test to the end of health plan enrollment, end of study period, or death. …”
Get full text

Association of elevated albumin-corrected anion gap with all-cause mortality risk in atrial fibrillation: a retrospective study by Jia Xu, Zhen Wang, Yun Wang, Xinran Chen, Lan Ma, Xiaochen Wang

“…Methods We identified individuals diagnosed with AF from the Medical Information Mart for Intensive Care (MIMIC)-IV database. Participants were categorized into quartiles based on their ACAG levels. …”
Get full text

Clinical Burden and Healthcare Resource Use of Asthma in Children in the UK by Gouia I, Joulain F, Zhang Y, Morgan CL, Khan AH

“…We assessed the clinical and economic burden of asthma in children in the UK to better understand the impact of pediatric asthma.Methods: This was a retrospective, case-matched, longitudinal analysis using the Clinical Practice Research Datalink GOLD database and linked patient-level data (Hospital Episode Statistics and Office for National Statistics datasets) of selected patient (aged 6– 11 years) records in 2017. …”
Get full text

The Relationship Between Novel Inflammatory Markers and Serum 25‐Hydroxyvitamin D Among US Adults by Hang Zhao, Yangyang Zhao, Yini Fang, Weibang Zhou, Wenjing Zhang, Jiecheng Peng

“…Methods We ultimately included a total of 5308 participants from the National Health and Nutrition Examination Survey (NHANES) database spanning 2007 to 2018. A multivariable linear regression model assessed the links between serum 25(OH)D and these novel inflammatory markers, with subgroup analyses for hypertension and diabetes. …”
Get full text

Nonlinear associations of the hs-CRP/HDL-C index with metabolic dysfunction-associated steatotic liver disease and advanced liver fibrosis in US adults: insights from NHANES 2017–2... by Bin Liang, Xue Qiu, Jiansheng Huang, Yequan Lu, Hairong Shen, Jianchao Ma, Yongyu Chen

“…The study analyzed secondary data from the National Health and Nutrition Examination Survey (NHANES) 2017–2018 database. The hs-CRP/HDL-C index was calculated by the quotient of hs-CRP and HDL-C. …”
Get full text

18F−Prostate−Specific Membrane Antigen PET/CT imaging for potentially resectable pancreatic cancer (PANSCAN−2): a phase I/II study by Jisce R. Puik, Thomas T. Poels, Gerrit K. J. Hooijer, Matthijs C. F. Cysouw, Joanne Verheij, Johanna W. Wilmink, Elisa Giovannetti, Geert Kazemier, Arantza Farina Sarasqueta, Daniela E. Oprea-Lager, Rutger-Jan Swijnenburg

“…Trial registration The trial is registered as PANSCAN-2 in the European Clinical Trials Database (EudraCT number: 2020–002185-14). Graphical Abstract…”
Get full text

Prevalence of complications and comorbidities associated with obesity: a health insurance claims analysis by Jay P. Bae, David R. Nelson, Kristina S. Boye, Kieren J. Mather

“…Methods This cross-sectional study analyzed individuals from all four regions (Midwest, Northeast, South, and West) of the US who had continuous insurance coverage from 2018 to 2020, using a large health insurance claims database (Merative™ MarketScan®). Identification of disorders relied on ICD-10 diagnosis code in patient claims and their prevalence was calculated. …”
Get full text

Paesaggi della memoria della Grande Guerra (1914-1918) Un cambiamento paradigmatico nella ricerca turistica sull’heritage di guerra by Myriam Jansen-Verbeke, Wanda George

“…L’inclusione nella survey di un numero di questioni aperte concernenti i valori, le esperienze, le memorie di circa 2.400 rispondenti (in 61 paesi), ha prodotto un database enorme, che consente di identificare alcune variabili rilevanti nel processo di turisticizzazione di paesaggi di guerra del passato. …”
Get full text

SUMO modified ETV1 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by facilitating CCL2 transcription in esophageal squamous cell carcinoma ce... by Tianci Han, Xiaoqi Guo, Junwei Xie, Wei Tong, Liang Zhang

“…Results In this study, through analysis of ESCC samples from TCGA database and the clinic, we noticed that ETV1 was highly expressed in ESCC tumor tissues and was associated with TAM infiltration. …”
Get full text

Argonaute2 and Argonaute4 Involved in the Pathogenesis of Kawasaki Disease via mRNA Expression Profiles by Zon-Min Lee, Hui-Chuan Chang, Shih-Feng Liu, Ying-Hsien Huang, Ho-Chang Kuo

“…Methods and Materials: We obtained mRNA-level gene expression profiles from leukocyte samples that had previously been gathered in another study and uploaded to the NCBI GEO database. The Human Transcriptome Array (HTA 2.0) analysis included 50 children with KD prior to IVIG (KD1), 18 children with KD three weeks post-IVIG (KD3), 18 non-febrile controls (HC), and 18 febrile controls (FC), which were arranged in the quoted publications for all materials and methods in order to collect data. …”
Get full text

A Mitochondria‐Related Signature in Diffuse Large B‐Cell Lymphoma: Prognosis, Immune and Therapeutic Features by Zhen‐Zhong Zhou, Jia‐Chen Lu, Song‐Bin Guo, Xiao‐Peng Tian, Hai‐Long Li, Hui Zhou, Wei‐Juan Huang

“…Methods Transcriptome profiles and clinical information were obtained from the Gene Expression Omnibus (GEO) database. The risk model was defined using Least Absolute Shrinkage and Selection Operator (Lasso) regression algorithm, and its prognostic value was further examined in independent datasets. …”
Get full text

Global Research Trends and Focus on the Link Between Heart Failure and NLRP3 Inflammasome: A Bibliometric Analysis From 2010 to 2024 by Lian Y, Zhang H, Xing W, Li S, Lai X, Jia S, Shang J, Liu H

“…Despite mounting evidence demonstrating the pivotal function of the NLRP3 inflammasome in HF, a thorough bibliometric examination of research focal points and trajectories in this domain has yet to be undertaken.Methods: Publications related to the NLRP3 inflammasome in HF were retrieved from the Web of Science database spanning 2010– 2024. The acquired data were subsequently analyzed utilizing various visualization instruments, including Citespace, VOSviewer, Scimago Graphica, and Microsoft Office Excel 2021.Results: A total of 282 papers were included in the analysis, authored by 2,130 researchers from 500 institutions across 34 nations/regions. …”
Get full text

Identification of SETD4 as an Onco‐Immunological Biomarker Encompassing the Tumor Microenvironment, Prognoses, and Therapeutic Responses in Various Human Cancers by Yuyun Zhong, Ruiqi Wang, Zijie Huang, Zhaoting Hu, Bin Peng, Bin Chen, Liyue Sun

“…Methods Utilizing The Cancer Genome Atlas database, and other publicly accessible platforms, we comprehensively analyzed SETD4 gene expression, methylation patterns, and prognostic significance. …”
Get full text

Novel Fusion Technique for High-Performance Automated Crop Edge Detection in Smart Agriculture by F. Martinez, James B. Romaine, P. Johnson, A. Cardona Ruiz, Pablo Millan Gata

“…For the training of each methods, a custom database has been created using a low-cost, low-power custom IoT node deployed on a real farm to provide the most accurate data. …”
Get full text

Comprehensive bioinformatics analysis identifies hub genes associated with immune cell infiltration in early-onset schizophrenia by Shasha Wu, Tailian Xue, Yilin Li, Weikang Chen, Yan Ren

“…Hub genes were identified through protein-protein interactions (PPIs) and the GeneMANIA database. The diagnostic potential of immune-associated hub genes was evaluated using ROC analysis. …”
Get full text

Novel Algorithm for Surgical Management of Cervical Ossification of Posterior Longitudinal Ligament: A Retrospective Cohort Study With 2‐Year Follow‐Up by Zhuyun Cai, Hui Kang, Lei Quan, Yilong Ren, Meng Fang, Yixuan Tan, Haochen Zhang, Xuhui Zhou, Jun Ma

“…Patient demographics, Japanese Orthopedic Association (JOA) scores, surgical time, imaging data before and 2 years after surgery, and the occurrence of complications were extracted from the database. Paired t‐test was used for intragroup comparison, and one‐way ANOVA test was used for the intergroup analyses. …”
Get full text

Patient experience and burden of haemolytic disease of the foetus and newborn: a systematic review by P. Maurice, J. McCallion, M. Fitzgibbon, J. N. Barthelmes, W. Karmous, E. J. Hardy, S. A. Mitchell, C. R. Mitchell, J. Lee, W. Noel, Andras Borsi, J. M. Jouannic

“…This systematic review (SR) aimed to identify and summarise real-world evidence (RWE) related to the patient burden/experience and economic burden of HDFN. Methods Electronic database searches supplemented by handsearching of grey literature, were conducted to identify studies that reported the clinical patient burden/experience, and economic burden of HDFN in Europe, the Middle East, and Africa (EMEA). …”
Get full text

Impact of Thrombocytopenia on In-Hospital Outcome in Patients Undergoing Percutaneous Coronary Intervention by Zhongxiu Chen, Zheng Liu, Nan Li, Ran Liu, Miye Wang, Duolao Wang, Chen Li, Kai Li, Fangbo Luo, Yong He

“…Using the West China Hospital Inpatient Sample database, patients who underwent PCI were identified from August 2012 to January 2019. …”
Get full text

SARS-CoV-2 SPIKE Antibody Levels can Indicate Immuno-Resilience to Re-infection: a Real-World Study by Yue Jin, Fei Yang, Christopher M. Rank, Stanley Letovsky, Peter Ramge, Simon Jochum

“…Methods In this real-world study, laboratory data from individuals tested for SARS-CoV-2 antibodies under routine clinical conditions were linked through tokenization to a United States medical insurance claims database to determine the risk of symptomatic/severe SARS-CoV-2 infection outcomes. …”
Get full text

Oncological and functional outcomes following treatment of T1a glottic squamous cell carcinoma with transoral laser microsurgery by Dennis E. Curry, David Forner, Matthew H. Rigby, Jonathan R. Trites, Martin Corsten, S. Mark Taylor

“…Methods This study is a retrospective cohort study performed from a prospectively collected tertiary center institutional TLM database. Patients who were diagnosed with T1a glottic SCC and underwent TLM as their primary treatment were included. …”
Get full text