Carbidopa/levodopa dose elevation and safety concerns in Parkinson's patients: a cross-sectional and cohort design by Michael S Okun, Peter Schmidt, David W Brodell, Nicole T Stanford, Charles E Jacobson

“…This study investigates the 800 mg threshold by using a prospectively collected database of patient information.Design A retrospective cohort study: (Part I) cross-sectional, (Part II) longitudinal.Setting and participants PD patients at a Movement Disorders Center in a large academic, tertiary medical setting.Outcome measures An analysis was performed using carbidopa/levodopa at dosages below and above the 800 mg threshold. …”
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Socio-economic inequality in the nutritional deficiencies among the world countries: evidence from global burden of disease study 2019 by Mohsen Bayati, Elham Arkia, Mehrnoosh Emadi

“…Methods Burden data of nutritional deficiencies and its subsets including protein-energy malnutrition, iodine deficiency, vitamin A deficiency, and dietary iron deficiency form GBD study and Human Development Index (HDI), a proxy for the socio-economic status of countries, from united nations database were collected. After descriptive statistics, the concentration index (CI) curve was used to measure socioeconomic inequality. …”
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Economic Burden of HIV in a Commercially Insured Population in the United States by Cindy Y. Chen, Prina Donga, Alicia K. Campbell, Babafemi Taiwo

“…**Methods:** This retrospective observational study utilized data from the IBM MarketScan® Commercial Claims and Encounters database. Adults with newly diagnosed HIV-1 or those initiated with PrEP were included (index date was the first HIV diagnosis or PrEP prescription, respectively, between January 1, 2016, and April 30, 2021). …”
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Trends in Specialty Training and National Institutes of Health Funding Among Surgeon-Scientists by Gabriel Velez, MD, PhD, Vinit B. Mahajan, MD, PhD, Ronald J. Weigel, MD, PhD, MBA, Steven R. Lentz, MD, PhD

“…We analyzed publicly available data from the National MD/PhD Program Outcomes Study and the Association of American Medical Colleges Graduate Medical Education Track database to identify trends in the number and proportion of MD/PhD graduates pursuing surgical specialties. …”
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A Drug-Induced Acute Pancreatitis Retrospective Study by Ann-Lorie Gagnon, Alexandre Lavoie, Marie-Pier Frigon, Alban Michaud-Herbst, Karine Tremblay

“…Cases were selected from the Quebec Ministry of Health hospitalizations registry (MED-ECHO) administrative public database. A medical chart review was performed in an attempt to characterize DIAP hospitalizations and to identify the imputable drugs. …”
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FGF2 and EGF for the Regeneration of Tympanic Membrane: A Systematic Review by Zhengcai Lou, Zihan Lou, Yumeng Jiang, Zhengnong Chen

“…Methods. The PubMed database was searched for relevant studies. Experimental and clinical studies reporting acute and chronic TM perforations in relation to two healing outcomes (success rate and closure time) and complications were selected. …”
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Discussion on Redundant Processing Algorithm of Association Rules Based on Hypergraph in Data Mining by Jintan Zhu

“…With the rapid advancement of big data, it is becoming a great problem for people to find objective information in the database. The relevance data processing rule for digging the information can be the way. …”
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Association between Red Blood Cell Distribution Width and In-Hospital Mortality among Congestive Heart Failure Patients with Diabetes among Patients in the Intensive Care Unit: A R... by Kai Zhang, Yu Han, Yu Xuan Gao, Fang Ming Gu, Tianyi Cai, Rui Hu, Zhao Xuan Gu, Jia Ying Liang, Jia Yu Zhao, Min Gao, Bo Li, Dan Cui

“…This retrospective study utilized data from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database, a comprehensive critical care repository. …”
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Prediction of Immune Infiltration Diagnostic Gene Biomarkers in Kawasaki Disease by Hongjun Ba, Yao Wang, Lili Zhang, Huishen Wang, Zhan-Peng Huang, Youzhen Qin

“…The Gene Expression Omnibus database was utilized to retrieve two freely accessible gene expression patterns (GSE68004 and GSE18606 datasets) from human KD and control specimens. 114 KD, as well as 46 control specimens, were searched for obtaining differentially expressed genes (DEGs). …”
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Routes to social prescribing outside National Health Service (NHS) structures: a systematic map by Kerryn Husk, Stephanie Tierney, Lucy Gavens, Emma Hazeldine, Sophie Westwood, Mohammad Hassannezhad

“…The review searched database and grey sources and synthesised findings relating to how social prescribing pathways’ function.Setting Community settings, outside of formal National Health Service (NHS) structures without statutory service input.Participants All participants that experienced pathways were included; no limits were applied.Interventions Non-NHS social prescribing pathways that included the core components of social prescribing.Main outcome measures Rich descriptions of functions of pathways.Results This mapping review included 17 studies. …”
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RHOBTB2 Variant p.Arg511Gln Causes Developmental and Epileptic Encephalopathy Type 64 in an Infant: A Case Report and Hotspot Variant Analysis by Qian Liu, Feifei Li, Qin Ruan, Nana Wang, Zhengjun Fan

“…We used Discovery Studio software to analyze the folding free energy of variant proteins, and the AlphaFold database to analyze structural alterations in mutant proteins. …”
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Drought before fire increases tree mortality after fire by C. Alina Cansler, Micah C. Wright, Phillip J. vanMantgem, Timothy M. Shearman, J. Morgan Varner, Sharon M. Hood

“…To evaluate whether drought increases the likelihood of post‐fire tree mortality, we used a large database of tree survival and mortality from 32 years of wildland fires covering four dominant western North American conifers. …”
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Occurrence and Impact of Gastrointestinal Bleeding and Major Adverse Cardiovascular Events during Sepsis: A 15-Year Observational Study by Ming-Shun Hsieh, Shu-Hui Liao, Vivian Chia-Rong Hsieh, Chorng-Kuang How

“…The medical claims records of 220,082 patients admitted for sepsis between 1999 and 2013 were retrieved from the nationwide database. The adjusted odds ratios (aORs) of composite outcomes including the hospital mortality, intensive care unit (ICU) admission, and mechanical ventilation (MV) in patients with a MACE or GIB were estimated by multivariate logistic regression and joint effect analyses. …”
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Exploring digital health interventions for pregnant women at high risk for pre-eclampsia and eclampsia in low-income and-middle-income countries: a scoping review by Emily Seto, Anam Shahil Feroz, Noreen Afzal

“…Objective To explore digital health interventions that have been used to support pregnant women at high risk for pre-eclampsia/eclampsia (HRPE/E) in low-income and middle-income countries (LMICs).Design Scoping review.Data source EMBASE, MEDLINE, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews and CINAHL were searched between 1 January 2000 and 20 October 2020.Eligibility criteria The review included original research studies that were published in English, involved pregnant women at HRPE/E and implemented digital health interventions for PE/E in LMICs.Data extraction and synthesis Two reviewers independently completed the data extraction for each of the 19 final articles. …”
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A Throughfall Collection Method Using Mixed Bed Ion Exchange Resin Columns by Mark E. Fenn, Mark A. Poth, Michael J. Arbaugh

“…Many studies have been published, providing a large database of throughfall deposition inputs to forests. …”
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Harnessing Internet Search Data as a Potential Tool for Medical Diagnosis: Literature Review by Gregory J Downing, Lucas M Tramontozzi, Jackson Garcia, Emma Villanueva

“…We searched for published peer-reviewed literature on the PubMed database between October and December 2023. …”
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The Obesity Paradox Revisited: Is Obesity Still a Protective Factor for Patients With High Comorbidity Burden or High-Complexity Procedures? by Hyo Jin Son, BSc, Denise W. Gee, MD, David Gomez, MD, PhD, James J. Jung, MD, PhD

“…We performed an observational study of adult patients undergoing major surgery using the 2016 to 2019 National Surgical Quality Improvement Program database. The outcome was 30-day mortality. We first estimated the risk-adjusted effects of BMI on mortality across the full cohort via multivariable regression and restricted cubic spline models. …”
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Using Linear Mixed-Effects Models to Analyze Historical Trends in Performance Strategies . Commentary on Majid Motavasseli’s Article “Interpretation of Cyclic Form in Bach’s ‘Goldb... by Bruno Gingras

“…Using a tempo measurement database comprising seventy-six selected recordings of the “Goldberg” cycle, I built a linear mixed-effects model predicting the main tempo for each recording from the following parameters: performer, variation number, instrument (piano or harpsichord), year of recording, variation type, and finally mode (major/minor) of the variation. …”
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Real-world Bleeding Outcomes and Costs Following Vascular Graft Anastomosis Using PROLENE Sutures with HEMO-SEAL Technology in Patients Undergoing Abdominal Aortic Aneurysm Repair by Nadia Y. Sutton, Niels-Derrek Schmitz

“…**Methods:** AAA repair procedures using hemostats and either HEMO-SEAL sutures or standard PROLENE sutures were identified from 2009 to 2013 using the Premier Healthcare Database. The primary outcome was the number and cost of hemostat units. …”
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Economic Outcomes and Incidence of Postsurgical Hypotension With Liposomal Bupivacaine vs Epidural Analgesia in Abdominal Surgeries by Margaret Holtz, Nick Liao, Jennifer H. Lin, Carl V. Asche

“…**Methods:** This retrospective analysis identified records of adults who underwent abdominal surgeries between January 2016 and September 2019 with either LB administration or traditional epidural analgesia using the Premier Healthcare Database. Economic outcomes included length of stay, hospital costs, rates of discharge to home, and 30-day hospital readmissions. …”
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