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6981
SLC7A11 is a potential therapeutic target and prognostic biomarker correlated with immune cell infiltration in cervical cancer
Published 2025-02-01“…Methods From the TCGA database, we analyzed SLC7A11 expression profiles and validated its promoting role in cervical cancer by in vitro. …”
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6982
Reforming the innovation system to deliver affordable medicines: a conceptual framework of pharmaceutical innovation as a complex adaptive system (forest) and theory of change
Published 2025-12-01“…Methods We inductively developed a novel conceptual framework of the PIS as a complex adaptive system (CAS) analogous to a forest. We constructed a database of 140 pharmaceutical innovation initiatives that sought to address global public interest objectives such as fair pricing or missing innovation. …”
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6983
A retrospective analysis of the malaria trend in Yemen over the sixteen-years, from 2006 to 2021
Published 2025-01-01“…Methods A retrospective analysis was conducted on secondary malaria data from the database from the Ministry of Public Health and Population in Yemen. …”
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6984
Microbial-based natural products as potential inhibitors targeting DNA gyrase B of Mycobacterium tuberculosis: an in silico study
Published 2025-01-01“…Consequently, targeting this enzyme is of particular interest in developing new drugs for the treatment of drug-resistant tuberculosis, including multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB).MethodsIn the present study, multiple computational tools were adopted to screen a microbial-based natural products database (NPAtlas) for potential inhibitors of the ATPase activity of MBT DNA gyrase.Results and discussionTwelve hits were initially identified as the top candidates based on their docking scores (ranging from −9.491 to −10.77 kcal/mol) and binding free energies (−60.37 to −73.21 kcal/mol). …”
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6985
Multimorbidity in Atherosclerotic Cardiovascular Disease and Its Associations With Adverse Cardiovascular Events and Healthcare Costs: A Real-World Evidence Study
Published 2024-03-01“…**Methods:** This is a retrospective observational cohort study using Aetna claims database. Patients with ASCVD were identified during the study period (1/1/2018–10/31/2021). …”
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6986
Graft survival and mortality outcomes after kidney transplant in patients with lupus nephritis: a systematic review and meta-analysis
Published 2024-12-01“…Literature search was conducted in PubMed, EMBASE and Scopus database for randomized controlled trials (RCTs), cohort, and case-control studies. …”
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6987
Rehabilitation Therapy Utilization in Patients with Parkinson’s Disease in Korea
Published 2018-01-01“…Patients were identified using the registration code for PD in the program for rare, intractable disease from the National Health Insurance Service-National Sample Cohort database, which consists of 979,390 Korean residents. …”
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6988
Identification of <i>Tinomiscium petiolare</i> from Vietnam using the DNA barcode
Published 2021-07-01“…Overall, the results of the study generated the most complete DNA barcode database of T. petiolare collected in Vietnam, contributing to the taxonomy and identification of this species.…”
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6989
Mortality in the families of children during the COVID-19 pandemic: evidence from a repeated cross-sectional study of children in the United States
Published 2025-01-01“…Methods We conducted a repeated cross-sectional analysis using Optum’s De-identified Clinformatics® Data Mart, a national claims database that includes privately insured children and families across the U.S. …”
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6990
TARREAN: A Novel Transformer with a Gate Recurrent Unit for Stylized Music Generation
Published 2025-01-01“…We evaluated the model using the Essen Associative Code and Folk Song Database, which contains 20,000 folk melodies from Germany, Poland, and China. …”
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6991
Specialized pediatric palliative care in Italy: where are we going? The Palliped 2022–2023 study
Published 2025-01-01“…Abstract Background The PalliPed project is a nationwide, observational, cross-sectional study designed with the aim of providing a constantly updated national database for the census and monitoring of specialized pediatric palliative care (PPC) activities in Italy. …”
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6992
Efficacy of preoperative pulmonary rehabilitation in lung cancer patients: a systematic review and meta-analysis of randomized controlled trials
Published 2025-01-01“…The PubMed, Embase, Cochrane Library, and Web of Science database were searched since inception up to March 2024. …”
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6993
Risk factors for hepatocellular carcinoma: an umbrella review of systematic review and meta-analysis
Published 2025-12-01“…Background Numerous meta-analyses have identified various risk factors for hepatocellular carcinoma (HCC), prompting a comprehensive study to synthesize evidence quality and strength.Methods This umbrella review of meta-analyses was conducted throughout PubMed, EMBASE, Web of Science, and Cochrane Database of Systematic Reviews. Evidence strength was evaluated according to the evidence categories criteria.Results We identified 101 risk factors throughout 175 meta-analyses. 31 risk factors were classified as evidence levels of class I, II, or III. …”
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6994
Comparison of the efficacy and safety of bupropion versus aripiprazole augmentation in adults with treatment-resistant depression: a nationwide cohort study in South Korea
Published 2025-01-01“…Data were collected from a nationwide claims database in South Korea. Patients prescribed bupropion were matched 1:1 with those prescribed aripiprazole. …”
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6995
MDFGNN-SMMA: prediction of potential small molecule-miRNA associations based on multi-source data fusion and graph neural networks
Published 2025-01-01“…The findings indicated that among the top 50 predicted miRNAs associated with Cisplatin, 5-Fluorouracil, and Doxorubicin, 42, 36, and 36 miRNAs, respectively, were corroborated by existing literature and the RNAInter database.…”
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6996
Association of LDL‐C/HDL‐C Ratio With Hyperuricemia: A National Cohort Study
Published 2025-01-01“…We extracted data from the China Health and Retirement Longitudinal Study (CHARLS) database from 2011 to 2016. Multivariable logistic regression, restricted cubic splines (RCSs) analysis, and linear correlation analysis were conducted to evaluate the association between LHR and risk of developing HUA. …”
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6997
Foreign Aid’s Effect on Political Risks for Foreign Direct Investment: A Literature Review
Published 2023-11-01“…This literature review aims to consolidate the academic exploration of the enduring classic foreign aid tools' impact on the political risks associated with foreign direct investment (FDI), and identifies prevalent limitations while suggesting approaches to overcome these challenges.The first section delineates the central theme and rationale behind the literature selection process, utilizing the Google Scholar database to contextualize the research within a comprehensive framework. …”
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6998
Seasonal Profile and Five-Year Trend Analysis of Malaria Prevalence in Maygaba Health Center, Welkait District, Northwest Ethiopia
Published 2021-01-01“…Data was extracted from the outpatient medical database. Chi-square (χ2) test and binary logistic regression model were used to analyze the retrospective data. …”
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6999
Treatment of Hepatitis C Post-Liver Transplantation Could Mitigate Discard Rates of Hepatitis C-Positive Deceased Donor Livers and Expand the Donor Pool
Published 2021-01-01“…This is a retrospective, observational study using Mid-America Transplant Services (MTS) database from 2008 to 2017. Comparison was made before the widespread use of DAAs 2008–2013 (pre-DAA) against their common practice use 2014–2017 (post-DAA). …”
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7000
Effect of Walking Modes and Temperatures on the Robustness of Ventilation Systems in the Control of Walking-induced Disturbances
Published 2022-06-01“…A ventilation system with high particle-removal efficiency may not be effective in controlling indoor disturbances. The database and method developed in this study could be beneficial for the control of human walking-induced disturbances in those settings that require a highly controlled indoor environment.…”
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