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  1. 4361
  2. 4362

    Heart disease in pregnancy and adverse outcomes: an umbrella review by Jiani Zhang, Jiani Zhang, Yuxin Ren, Yuxin Ren, Bingjie Li, Qi Cao, Qi Cao, Xiaodong Wang, Xiaodong Wang, Haiyan Yu, Haiyan Yu

    Published 2025-02-01
    “…BackgroundHeart disease in pregnancy encompasses both congenital heart disease and maternal-acquired heart disease, both of which are associated with an increased risk of various adverse outcomes for mothers and their offspring.ObjectiveThe objective of the study was to review and summarize the evidence regarding the association between heart disease in pregnancy and adverse outcomes in mothers and their offspring.Data sourcesA comprehensive search was conducted in Embase, PubMed, Web of Science, and the Cochrane Database of Systematic Reviews from inception to March 2024. …”
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  3. 4363

    Oral Cyclophosphamide for Patients With Metastatic Castration-Resistant Prostate Cancer in a Scenario of Limited Health Care Resources by Diana del Cisne Pineda, Gabriel Berlingieri Polho, Yumi Ricucci Shinkado, Gustavo Alves Contado, Nathalia de Souza Crusoe, Vivian Naomi Horita, Joao Carlos Resende, Jamile Almeida Silva, Guilherme Fialho de Freitas, David Queiroz Muniz, Caio V. Suartz, Leopoldo Alves Ribeiro-Filho, Paulo M. Hoff, José Mauricio Mota

    Published 2025-01-01
    “…However, cyclophosphamide is currently underutilized in routine clinical practice given the lack of survival benefit and the emergence of more effective treatments.METHODSWe retrospectively reviewed our institutional database to identify patients with mCRPC treated with cyclophosphamide. …”
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  4. 4364

    BCL-2 overexpression exosomes promote the proliferation and migration of mesenchymal stem cells in hypoxic environment for skin injury in rats by Ying Wang, Guang Li, Guofeng Li, Yutao Pan, Zhongmin Liu

    Published 2025-01-01
    “…GO analysis and KEGG analysis were carried out, and the grope tool of Link omics database was used to evaluate PPI information and other core path analysis information. …”
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  5. 4365

    Incidence of constrained condylar and hinged knee implants and mid- to long-term survivorship: a register-based study from the Nordic Arthroplasty Register Association (NARA) by Jake von Hintze, Ville Ponkilainen, Annette W-Dahl, Nils P Hailer, Ove Furnes, Anne M Fenstad, Mona Badawy, Alma B Pedersen, Martin Lindberg-Larsen, Mika J Niemeläinen, Keijo Mäkelä, Antti Eskelinen

    Published 2025-02-01
    “…Methods: From 2000 to 2017, 5,134 CCK and 2,515 RHK primary TKAs were identified from the NARA database. Kaplan–Meier (K–M) survival and flexible parametric survival model (FPSM) analyses were performed to estimate revision risk, expressed as hazard ratio (HR) with 95% confidence intervals (CI), with minimally stabilized (MS) TKA acting as the control group (n = 456,137). …”
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  6. 4366

    Development and Validation of a Cost-Effective Machine Learning Model for Screening Potential Rheumatoid Arthritis in Primary Healthcare Clinics by Wu W, Hu X, Yan L, Li Z, Li B, Chen X, Lin Z, Zeng H, Li C, Mo Y, Wu Y, Wang Q

    Published 2025-02-01
    “…Guided by experienced rheumatologists, we built a comprehensive database with 26 clinical features. Using 10 classical machine learning algorithms, we developed screening models. …”
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  7. 4367

    Germline BRCA testing in Denmark following invasive breast cancer: Progress since 2000 by Aleksandar M. Kostov, Maj-Britt Jensen, Bent Ejlertsen, Mads Thomassen, Caroline Maria Rossing, Inge S. Pedersen, Annabeth H. Petersen, Lise Lotte Christensen, Karin A.W. Wadt, Anne-Vibeke Lænkholm

    Published 2025-01-01
    “…Material and methods: From the Danish Breast Cancer Group (DBCG) clinical database, we included 65,117 females with unilateral stage I–III BC diagnosed in 2000–2017, of whom 9,125 (14%) were BRCA tested. …”
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  8. 4368

    Effect of Physical Activity on Physical and Mental Health in Young Cancer Patients and Survivors: A Systematic Review of RCTs and CCTs by Ann Christin Schneider, Sofia Anzeneder, Lars Rehbein, Eva Katharina Brack, Mirko Schmidt, Valentin Benzing

    Published 2025-01-01
    “…Physical exercise training interventions for children and young adults during and after treatment for childhood cancer. Cochrane Database of Systematic Reviews, 3, CD008796. https://doi.org/10.1002/14651858.CD008796.pub3 Krull, K. …”
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  9. 4369

    Development and validation of a machine learning model to predict the risk of lymph node metastasis in early-stage supraglottic laryngeal cancer by Hongyu Wang, Hongyu Wang, Hongyu Wang, Zhiqiang He, Zhiqiang He, Zhiqiang He, Jiayang Xu, Jiayang Xu, Ting Chen, Ting Chen, Ting Chen, Jingtian Huang, Jingtian Huang, Jingtian Huang, Lihong Chen, Lihong Chen, Lihong Chen, Xin Yue, Xin Yue, Xin Yue

    Published 2025-01-01
    “…This study seeks to create and validate a predictive model through the application of machine learning (ML) algorithms.MethodsThe training set and internal validation set data were extracted from the Surveillance, Epidemiology, and End Results (SEER) database. Data from 78 early-stage SGLC patients were collected from Fujian Provincial Hospital for independent external validation. …”
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  10. 4370

    The intellectual paradigm and scientific mapping of brand image in International Researches by Maryam Najafi Yazdi, Seyed Hassan Hataminasab, Shahnaz Nayebzadeh

    Published 2025-02-01
    “…This study was conducted on 521 articles in the WOS database based on the interpretative paradigm and systematic review method based on defined search terms. …”
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  11. 4371

    Regulatory role of lnc-MAP3K13-3:1 on miR-6894-3p and SHROOM2 in modulating cellular dynamics in hepatocellular carcinoma by Kuai Chen, Manqin Zhu, Qinghua Hu, Hui Huang, Ka Chen, Xia Shuai, Jinshi Huang, Qiang Tao, Zhibin Guo

    Published 2025-01-01
    “…Consequently, identifying molecular targets that specifically inhibit the proliferation and metastasis of HCC cells is critical for improving treatment outcomes. Database analysis using Targetscan identified complementary binding sites for the human-specific miRNA hsa-miR-6894-3p (hereafter referred to as miR-6894-3p) on SHROOM2, and Starbase data suggested a potential regulatory interaction between lnc-MAP3K13-3:1 and miR-6894-3p in liver cancer. …”
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  12. 4372

    Identification and Mass Spectrometric Fragmentation Pathways of Chemical Components in the Traditional Chinese Medicine Formula of Jiuwei Decoction by Jia-yu ZHAO, Yue-guang LYU, Tong XIN, Qian-qian GUO, Wen-ying ZHANG, Jin-hong LI, Hong-yu XUE, Qiang MA

    Published 2025-01-01
    “…Accurate mass information of precursor ions and fragment ions was meticulously compared with various databases, including the Orbitrap Traditional Chinese Medicine Library (OTCML), as well as other online databases such as TCMSP, ChemSpider, PubChem, PubMed, and Web of Science, in addition to a self-curated database for identification purposes. …”
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  13. 4373

    Evolving trends in lung cancer risk factors in the ten most populous countries: an analysis of data from the 2019 Global Burden of Disease StudyResearch in context by Chinmay T. Jani, Samuel A. Kareff, Dan Morgenstern-Kaplan, Ana S. Salazar, Georgina Hanbury, Justin D. Salciccioli, Dominic C. Marshall, Joseph Shalhoub, Harpreet Singh, Estelamari Rodriguez, Gilberto Lopes

    Published 2025-01-01
    “…Methods: We extracted overall and risk-factor-associated TBL cancer ASMR of the ten most populated countries for 1990–2019 from the Global Burden of Disease (GBD) database using the dedicated results tool (http://ghdx.healthdata.org/gbd-results-tool). …”
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  14. 4374
  15. 4375

    Global research trends in Chinese medicine for the treatment of non-alcoholic fatty liver disease (NAFLD): A bibliometric study by Kangjie li, Jie Wang, Ming Dang, Runxin Ren, Maomao Fu, Jing Wang, Qiao Zhang, Chongbo Zhao

    Published 2025-03-01
    “…Specifically, the search focused on English articles and review articles indexed in the SCI-E and SSCI databases, spanning from January 1, 2012, to October 30, 2024. …”
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    Article
  16. 4376

    Risk Factors of Portal Vein Thrombosis in Patients with Different Child-Pugh Classes Liver Cirrhosis by M. Yu. Nadinskaia, Kh. B. Kodzoeva, K. A. Gulyaeva, M.-D. E. Khen, D. I. Koroleva, M. A. Privalov, A. Kh. Tekaeva, V. R. Fedorov, S. G. Prokofev

    Published 2023-08-01
    “…The Case group included 130 patients with newly diagnosed PVT not caused by invasive hepatocellular carcinoma (HCC); 29 patients were assigned to class A, 101 patients were assigned to class B/C. From the database of cirrhotic patients without PVT 60 Controls for class A and 205 for B/C were selected using sratified randomization by sex, age and etiology of cirrhosis. …”
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    Article
  17. 4377

    Characteristics of Traditional Human Settlement Landscapes on Bedrock Islands in Guangdong Based on the “Ao” Unit by Ying PAN, Linxi CHEN, Ying SHI

    Published 2025-02-01
    “…Through this approach, a robust database of the Ao units on Nan’ao Island is meticulously compiled, encompassing information such as location, area, industry type, historical background, cultural beliefs, and origins of the island’s immigrants. …”
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    Article
  18. 4378

    Prevalence and management of hypertension in Turner syndrome: data from the International Turner Syndrome (I-TS) registry by Shani A D Mathara Diddhenipothage, Katharina J Beck, Gayana Amiyangoda, Jillian Bryce, Luminita Cima, Katya De Groote, Yana Deyanova, Evgenia Globa, Gloria Herrmann, Anders Juul, Anna Sophie L Kjaer, Anette Tønnes Pedersen, Sukran Poyrazoglu, Ursina Probst-Scheidegger, Theo C J Sas, Simona Fica, Sumudu Nimali Seneviratne, Justyna Karolina Witczak, Elizabeth Orchard, Jeremy W Tomlinson, S Faisal Ahmed, Helen E Turner

    Published 2025-01-01
    “…Objective: To investigate the prevalence and patterns of hypertension diagnosis and management in adult patients with TS who are registered in a large international multicentre database (TS-HTN study). Methods: Retrospective multicentre observational study of patients aged ≥18 years included in the I-TS (International-TS) registry (2020–2022), using registry and participating centre-collected data. …”
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  19. 4379

    Functional near-infrared spectroscopy for the assessment and treatment of patients with disorders of consciousness by Nan Wang, Nan Wang, Nan Wang, Yifang He, Sipeng Zhu, Dongsheng Liu, Xiaoke Chai, Xiaoke Chai, Qiheng He, Tianqing Cao, Jianghong He, Jingqi Li, Juanning Si, Yi Yang, Yi Yang, Yi Yang, Yi Yang, Yi Yang, Yi Yang, Yi Yang, Jizong Zhao, Jizong Zhao

    Published 2025-02-01
    “…Specifically, it investigates the potential value of combining fNIRS with brain-computer interfaces (BCIs) and closed-loop neuromodulation systems for patients with DoC, aiming to elucidate mechanisms that promote neurological recovery.MethodsA systematic analysis was conducted on 155 studies published between January 1993 and October 2024, retrieved from the Web of Science Core Collection database.ResultsAnalysis of 21 eligible studies on neurological diseases involving 262 DoC patients revealed significant findings. …”
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    Article
  20. 4380

    Identification of positive selection signatures associated with milk and composition traits in Murciano-Granadina and Barki by Hossein Mohammadi, amir hossien khaltabadi farahani, Mohammad Hossein Moradi

    Published 2024-12-01
    “…Additionally, the latest published version of Animal genome database was used for defining QTLs associated with economically important traits in identified locations. …”
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