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2821
TGF-β signaling orchestrates cancer-associated fibroblasts in the tumor microenvironment of human hepatocellular carcinoma: unveiling insights and clinical significance
Published 2025-01-01“…In our recent study, drawing from the GEO database, we identified two fibroblast subtypes in HCC through single-cell RNA sequencing (scRNA-seq) and explore the expression and distribution of TGF-β and its receptors in the TME of HCC. …”
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2822
Molecular genetics of idiopathic pulmonary fibrosis
Published 2022-06-01“…Analysis of the MDTE database (miRNAs derived from Transposable Elements) allowed the detection of 12 different miRNAs derived in evolution from transposons and associated with IPF (miR-31, miR-302, miR-326, miR-335, miR-340, miR-374, miR-487, miR-493, miR-495, miR-630, miR-708, miR-1343). …”
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2823
Acoustic and perceptual impact of face masks on speech: A scoping review.
Published 2023-01-01“…The search was completed in May 2021 across the following databases: PubMed, EMBASE, PsycINFO, Web of Science, and Google Scholar. …”
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2824
Metastatic melanoma: An integrated analysis to identify critical regulators associated with prognosis, pathogenesis and targeted therapies.
Published 2025-01-01“…A microarray dataset, GSE15605, including 12 metastatic-melanoma and sixteen normal skin (NS) samples, were obtained from the GEO database. After exploration of DEGs of NS and metastatic-melanoma, identification of relevant transcription factors (TFs) and kinases, the Gene Ontology (GO), and pathways analyses of DEGs were performed. …”
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2825
Diabetic ketoacidosis and hyperglycemic hyperosmolar state are associated with higher in-hospital mortality and morbidity in diabetes patients hospitalized with ST-elevation myocar...
Published 2025-01-01“…<h4>Methods</h4>We used the National Readmission Database (2016-2019) to extract patients with T2DM and STEMI at baseline. …”
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2826
Learning deep forest for face anti-spoofing: An alternative to the neural network against adversarial attacks
Published 2024-10-01“…When testing with adversarial examples, the increment of EER was less than 3%, more robust than CNN and ViT. On the benchmark database IDIAP REPLAY-ATTACK, a 0% EER was achieved. …”
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2827
Pregnancy outcomes in patients with psoriasis, psoriatic arthritis, or axial spondyloarthritis receiving ixekizumab
Published 2022-07-01“…Detailed information about pregnancy and related outcomes across these indications in patients exposed to ixekizumab is lacking.Objectives To evaluate pregnancy outcomes after maternal or paternal exposure to ixekizumab in patients with psoriasis, PsA, or axSpA.Methods Pregnancy cases from clinical trials and post-marketing reports, associated with either maternal or paternal exposure to ixekizumab cumulatively through 22 March 2019, were identified in the Eli Lilly Global Safety Database and described separately.Results One hundred and ninety-three ixekizumab-exposed pregnancies were identified. …”
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2828
Detection of plasmids in Salmonella from poultry and investigating the potential horizontal transfer of antimicrobial resistance and virulence genes
Published 2025-01-01“…Both PlasmidFinder 2.1 and VRprofile2 were employed to detect plasmids in Salmonella sequences downloaded from the National Center for Biotechnology Information (NCBI) Reference Sequences (RefSeq) database, and then oriTfinder was used to determine the conjugative ability of plasmids. …”
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2829
Elucidating the role of compositional and processing variables in tailoring the technological functionalities of plant protein ingredients
Published 2025-01-01“…The review presents four sections describing: (i) the approach followed for the construction of a database of PP ingredient functionalities; (ii) the composition and processing factors relevant to PP ingredients; (iii) PP ingredient functional properties and methods used for their determination; (iv) the effect of composition and processing factors on PP ingredient functionalities. …”
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2830
An overview of the status, productivity and determinants of improved forage technology adoption in Ethiopia: a review
Published 2023-10-01“…We conducted a literature search on the reputable journal database by searching for “improved forage technology”, “determinants of forage technology”, “adoption”, “status of forage production in Ethiopia”, and “forage production limitations”. …”
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2831
MVK, induced by Kras, represses cGAS-Sting signalling in lung adenocarcinoma
Published 2025-01-01“…In addition, we found a negative correlation between MVK expression and CD8+ T-cell infiltration via a public database analysis. In summary, our study demonstrates the importance of the nonmetabolic function of MVK in modifying the immunological milieu and provides new targets for lung adenocarcinoma therapy.…”
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2832
Multipotent Effect of Clozapine on Lipopolysaccharide-Induced Acetylcholinesterase, Cyclooxygenase-2,5-Lipoxygenase, and Caspase-3: In Vivo and Molecular Modeling Studies
Published 2025-01-01“…Structure-based virtual screening of US-FDA-approved molecules from the ZINC15 database identified clozapine (CLOZ) as the dual inhibitor of COX-2 and AChE, with significant binding affinity. …”
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2833
Highlights of 2023-Print Issue
Published 2023-12-01“…Additional features include • A [safety alert about clozapine](https://patientsafetyj.com/article/90674), a last-line therapy for schizophrenia that may cause serious, life-threatening side effects if it is not dosed appropriately • Data analyses from the largest event reporting database of its kind in the United States, including [patient safety trends in serious events and incidents](https://patientsafetyj.com/article/74752), and [healthcare-associated infections in nursing homes](https://patientsafetyj.com/article/74494) • An interview with pediatrician Dr. …”
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2834
Identification of a Mutation in the Novel Compound Heterozygous CFTR in a Chinese Family with Cystic Fibrosis
Published 2020-01-01“…As c.400 A > G is not currently listed in the Cystic Fibrosis Mutation Database, this information, regarding the CF-causing mutations in two Chinese patients, is of interest.…”
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2835
Transcriptional Regulation of Fucosyltransferase 1 Gene Expression in Colon Cancer Cells
Published 2013-01-01“…In this study, we clarified the transcriptional regulation of FUT1 in the DLD-1 colon cancer cell line, which has high expression of Lewis B and Lewis Y antigens, expresses the FUT1 gene, and shows α1,2-fucosyltransferase (FUT) activity. 5′-rapid amplification of cDNA ends revealed a FUT1 transcriptional start site −10 nucleotides upstream of the site registered at NM_000148 in the DataBase of Human Transcription Start Sites (DBTSS). …”
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2836
The type of infections and the use of antibiotics among patients with rheumatoid arthritis: A review
Published 2025-01-01“…An electronic literature search was conducted using the MEDLINE database, with the indicated search keywords: infections, antibiotics, use, patients, rheumatoid, and arthritis. …”
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2837
Long-Term Mortality following Acute Noninvasive Ventilation for Obesity-Related Respiratory Failure: A Retrospective Single-Centre Study
Published 2023-01-01“…Records from April 2013 to March 2020 were accessed from a NIV quality database at an acute teaching hospital. Adults with hypercapnic ORRF requiring acute NIV were included. pH data were grouped by threshold (pH≤ and >7.25) and correlated with time from presentation to death; multivariable analysis was performed using Cox proportional hazards. …”
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2838
Longitudinal Invariance Testing Of The Knee Injury Osteoarthritis Outcome Score For Joint Replacement Scale (KOOS-JR)
Published 2023-10-01“… # Methods Longitudinal data extracted from the Surgical Outcome System (SOS) database of 13,470 knee pathology patients who completed the KOOS-JR at baseline, three-months, six- months, and one-year. …”
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2839
Exosomes in neuron-glia communication: A review on neurodegeneration
Published 2024-09-01“…Furthermore, an exploration of the Clinicaltrials.gov database was undertaken to identify clinical trials related to cellular signaling, utilizing analogous terminology. …”
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2840
Community interventions for pandemic preparedness: A scoping review of pandemic preparedness lessons from HIV, COVID-19, and other public health emergencies of international concer...
Published 2024-01-01“…We drew on peer-reviewed and grey literature from the HIV (from 2000) and COVID-19 pandemics and recent public health emergencies of international concern (from 2008), identified through systematic searches in MEDLINE, Scopus, the Cochrane Collaboration database, supplemented by keyword-structured searches in GoogleScholar and websites of relevant global health organisations. …”
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