MiR-216a-3p inhibits the cytotoxicity of primary natural killer cells by Rowan Abdelbary, Rowan Abdelbary, Manon Ragheb, Manon Ragheb, Shereen A. El Sobky, Nagwa El-Badri, Nourhan Aboud, Ahmed Tawheed, Asmaa Gomaa, Mona Zidan, Ramy K. Aziz, Abd Elrahman Abouzid, Radwa Ayman Salah, Mohamed El-Kassas, Imam Waked, Ahmed Moustafa, Ahmed Moustafa, Injie Omar Fawzy, Nada El-Ekiaby, Ahmed Ihab Abdelaziz

“…Our project aims to investigate the role of miR-216a-3p in the regulation of NK cell cytotoxicity, especially since it plays a tumor suppressor role in the context of HCC.MethodsTo achieve our aim, we isolated NK cells from the whole blood of 86 patients with HCC and 23 healthy controls. …”
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Assessment of Cytotoxicity and Genotoxicity Potential of Effluents from Bahir Dar Tannery Using Allium cepa by Tayachew Admas, Bizuayehu Kerisew

“…Among tannery effluent chemicals, chromium and lead have cytotoxicity and genotoxicity potentials on Allium cepa. …”
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Initial Cytotoxicity of Mineral Trioxide Aggregate (MTA) during Setting on Human Mesenchymal Stem Cells by Soo-Youn Kim, Su-Min Lee, Jung-Hwan Lee

“…The extracts were exposed to hMSCs, and cytotoxicity was evaluated by the WST assay. In the present study, all 4 MTA products tested showed severe cytotoxicity at 100% and 50% extract, while 25% and 12.5% revealed 30∼100% depending on the MTA products. …”
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Cardiorenal Syndrome Type 5: In Vitro Cytotoxicity Effects on Renal Tubular Cells and Inflammatory Profile by Alessandra Brocca, Grazia Maria Virzì, Chiara Pasqualin, Silvia Pastori, Stefano Marcante, Massimo de Cal, Claudio Ronco

“…Our results underline the cytotoxic effect of CRS Type 5 mediators on RTC viability, probably due to the activation of both intrinsic and extrinsic pathways of apoptosis and to the deregulation of cytokine release. …”
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Cytotoxic activity of Fomitopsis betulina against normal and cancer cells – a comprehensive literature review by Paulina Nowotarska, Maciej Janeczek, Benita Wiatrak

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IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3 by Huiyue Dong, Huiyue Dong, Ling Zhu, Ling Zhu, Jingjing Sun, Jingjing Sun, Qiuyan Chen, Qiuyan Chen, Pengyang Liu, Pengyang Liu, Wei Zhang, Huajing Zeng, Rong Lin, Rong Lin, Zongyang Yu, Zongyang Yu, Jun Lu, Jun Lu, Jun Lu, Jun Lu

“…Meanwhile, compared to the groups treated with either IFNβ or RSL3 alone, the combination treatment of IFNβ and RSL3 significantly inhibited the growth of HT1080 three-dimensional (3D) spheroids and tumor in a mouse xenograft model.ConclusionsOur work reveals a role for IFNβ in promoting ferroptosis and provides evidence that IFNβ could be used with RSL3 to increase cytotoxic effects in tumor cells.…”
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Green Biosynthesis of Silver Nanoparticles from Moringa oleifera Leaves and Its Antimicrobial and Cytotoxicity Activities by Gufran Mahmood Mohammed, Sumaiya Naeema Hawar

“…Moringa oleifera AgNPs inhibited human melanoma cells A375 line significant concentration-dependent cytotoxic effects. The powerful bioactivity of the green synthesized silver nanoparticles from medical plants recommends their biomedical use as antimicrobial as well as cytotoxic agents.…”
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Viability Reagent, PrestoBlue, in Comparison with Other Available Reagents, Utilized in Cytotoxicity and Antimicrobial Assays by Namrita Lall, Cynthia Joan Henley-Smith, Marco Nuno De Canha, Carel Basson Oosthuizen, Danielle Berrington

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Studies on the Dual Cytotoxicity and Antioxidant Properties of Berberis vulgaris Extracts and Its Main Constituent Berberine by Lamyae El khalki, Mounir Tilaoui, Abdeslam Jaafari, Hassan Ait Mouse, Abdelmajid Zyad

“…Interestingly, no cytotoxic effect was observed against normal cells. …”
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Exploring the influence of light conditions on the antifungal, antioxidant, and cytotoxic potential of N. persica A1387 by Bahareh Nowruzi, Radin Norouzi, Romina Norouzi

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Retracted: In Vitro Evaluation of the Cytotoxic Potential of Environmental Contaminant Mixtures Present in Water for Human Use by Adsorption Science and Technology

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in vitro evaluation of the efficiency of Artemisia judaica leaf extract on sporulation of Eimeria papillate oocysts and its cytotoxicity by M.A. Esam, N.M. Saleh, A.G. Rewaida, A.Q.H. Waleed, A. Afaf, A.A. Sarah, Al-Q. Saleh

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Evaluation of phytochemical composition, antioxidant, cytotoxic and in silico studies of ethyl acetate fractions of Tristaniopsis merguensis leaves by Boima Situmeang, Respati Tri Swasono, Tri Joko Raharjo

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Evaluation of acute plant toxicity, antioxidant activity, molecular docking and bioactive compounds of lemongrass oil isolated from Omani cultivar by Haneen Al Weshahi, Mohammad Sohail Akhtar, Salem Said Al Tobi, Amzad Hossain, Shah Alam Khan, Alia Bushra Akhtar, Sadri Abdullah Said

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<i>shp-2</i> gene knockout upregulates CAR-driven cytotoxicity of YT NK cells by V. G. Subrakova, S. V. Kulemzin, T. N. Belovezhets, A. N. Chikaev, N. A. Chikaev, O. A. Koval, A. A. Gorchakov, A. V. Taranin

“…Adoptive transfer of NK cells is a promising approach to fight cancer; however, for their successful use in cancer treatment, it is necessary to ensure their robust accumulation at tumor foci, provide resistance to the immunosuppressive tumor microenvironment, and to engineer them with higher cytotoxic activity. NK lymphocytes are known to kill cancer cells expressing a number of stress ligands; and the balance of signals from inhibitory and activating receptors on the surface of the NK cell determines whether a cytotoxic reaction is triggered. …”
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Communication: Synthesis of a Novel Triphenyltin(IV) Derivative of 2- Mercaptonicotinic Acid with Potent Cytotoxicity in vitro by Marianna N. Xanthopoulou, Sotiris K. Hadjikakou, Nick Hadjiliadis, Markus Schürmann, Klaus Jurkschat, Jayne Binolis, Spyros Karkabounas, Konstantinos Charalabopoulos

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In Vitro Antioxidant and Cytotoxic Activities of Some Marine Sponges Collected off Misamis Oriental Coast, Philippines by A. P. Rivera, M. M. Uy

“…The antioxidant and cytotoxic activities of the marine sponges may be attributed to the zoochemicals present. …”
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3D scaffold of hydroxyapatite/β tricalcium phosphate from mussel shells: Synthesis, characterization and cytotoxicity by Sabrina Cunha da Fonseca, Rosangela Borges Freitas, Anne Raquel Sotiles, Zelinda Schemczssen-Graeff, Inaiê Maiala De Almeida Miranda, Stellee Marcela Petris Biscaia, Fernando Wypych, Edvaldo da Silva Trindade, Moira Pedroso Leão, João César Zielak, Célia Regina Cavichiolo Franco

“…Objectives: To synthesize, characterize, and evaluate the cellular cytotoxicity of a 3D biomaterial based on HA and β-TCP from mussel shells. …”
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Effect of Nano-Silica on Mechanical Properties and Cytotoxicity of Calcium-Silicate-Based Root Canal Filling Materials by Hao He, Bolang Hao, Xiang Xiong, Yi Cheng, Jia Lou, Zheyu He, Dongyang Li, Zhihuan Wang, Jian Qin

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Antiplasmodial and Cytotoxic Activities of Extracts of Selected Medicinal Plants Used to Treat Malaria in Embu County, Kenya by Bibianne Waiganjo, Gervason Moriasi, Jared Onyancha, Nelson Elias, Francis Muregi

“…Based on the fact that studies involving antimalarial medicinal plants as potential sources of efficacious and cost-effective pharmacotherapies are far between, this research was designed to investigate antiplasmodial and cytotoxic activities of organic and aqueous extracts of selected plants used by Embu traditional medicine practitioners to treat malaria. …”
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