An investigation of the dose-dependent safety of bemiparin sodium: A cell culture study by Emre Kubat, Ozer Aylin Gurpinar, Tuna Demirkiran

“…Results: The highest cytotoxic effect was observed in dilution I compared to the control group (p [Turk J Vasc Surg 2024; 33(2.000): 59-63]…”
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Inhibitory Activity of Illicium verum Extracts against Avian Viruses by Mohammed S. Alhajj, Mahmood A. Qasem, Saud I. Al-Mufarrej

“…This study aimed at screening the inhibitory activity of Illicium verum extracts against avian reovirus, infectious bursal disease virus (IBDV), Newcastle disease virus (NDV), and infectious laryngotracheitis virus (ILTV). The cytotoxic and antiviral actions of 3 extracts, absolute methanol (100MOH), 50% methanol (50MOH), and aqueous extracts (WA.), were evaluated by MTT assay. …”
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Interleukin-2 receptor β chain as a possible target for low doses of mafosfamide by A. Pukhalsky, A. Toptygina, S. Khaidukov

“…The 7-day cytotoxic lymphocytes (CTL) induced in mixed lymphocyte culture express only the chain of the interleukin-2 receptor (IL-2R). …”
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Investigation of the effıciency of pomegranate (punica granatum l.) peel extract on herpes simplex virus-1 by Irmak Dik, Hatice Pelin Aslım

“…It was determined that this cell culture did not cause cytotoxicity at concentrations lower than 0.87 mg/ mL. …”
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Highly Effective Crosslinker for Redox-Sensitive Gene Carriers by Lin Lin, Jie Chen, Yingying Hu, Huapan Fang, Kui Wang, Huayu Tian, Xuesi Chen

“…PEI1.8k shows significantly lower cytotoxicity than its high molecular weight counterparts. …”
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Hepatitis C Virus, Cryoglobulinemia, and Kidney: Novel Evidence by Fabrizio Fabrizi

“…Various approaches have been tried for the treatment of HCV-related glomerulonephritis, including immunosuppressive therapy (corticosteroids and cytotoxic agents), plasma exchange and antiviral agents. …”
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Conventional Chemotherapy and Inflammation: What Is the Role of the Inflammasome in the Tumor Microenvironment? by Chiara Colarusso, Michela Terlizzi, Simone Di Caprio, Anna Falanga, Emmanuel D’Andria, Roberta d’Emmanuele di Villa Bianca, Rosalinda Sorrentino

“…In this scenario, the conventional chemotherapy has proven to induce immunogenic cell death in that the release of danger-associated alarmins can foster the cytotoxic immunity following the blockade of immune checkpoints. …”
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Immune response in virus model structured by cell infection-age by Cameron Browne

“…This paper concerns modeling the coupled within-host population dynamics of virus and CTL (Cytotoxic T Lymphocyte) immune response. There is substantial evidence that the CTL immune response plays a crucial role in controlling HIV in infected patients. …”
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THERAPY-RELATED MYELOID NEOPLASMS: CONSIDERATIONS FOR PATIENTS’ CLINICAL EVALUATION. by Raffaele Palmieri, Ilaria Del Principe, Luca Maurillo, Adriano Venditti, Francesco Buccisano

“… Therapy-related myeloid neoplasms (t-MNs) encompass a specific sub-group of myeloid malignancies arising after exposure to radio/cytotoxic agents for the treatment of unrelated diseases. …”
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Combination Immunotherapy with 4-1BBL and CTLA-4 Blockade for the Treatment of Prostate Cancer by Kuang Youlin, Zhang Li, Weng Xiaodong, Liu Xiuheng, Zhu Hengchen

“…Interruption of immune regulatory pathways via activation of 4-1BB or cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) blockade appears to be a promising strategy for cancer immunotherapy. …”
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Precision medicine using molecular-target drugs in psoriatic arthritis by Ippei Miyagawa, Yoshiya Tanaka

“…As the pathology of PsA has been clarified, molecular-targeted drugs targeting tumor necrosis factor-α, interleukin (IL)-17A, IL-17A/F, IL-17 receptor, IL-12/23(p40), IL-23p19, Cytotoxic T-lymphocyte Antigen-4 (CTLA-4), Janus kinase, and phosphodiesterase-4 have been developed and are widely used in clinical practice. …”
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Towards a long-term model construction for the dynamic simulation of HIV infection by M. Hadjiandreou, Raul Conejeros, Vassilis S. Vassiliadis

“…The formulatedmodel considers all important population compartments including macrophages,latently-infected CD4+ T-cells, and cytotoxic T-lymphocytes (CTLs),an attempt which in many respects is novel in the area of HIV modelling.The ranges of the model parameters and initial conditions were obtainedfrom literature, and their values were determined in this work directlyby fitting published clinical data. …”
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Inflammation and Macular Oedema after Pars Plana Vitrectomy by Vito Romano, Martina Angi, Fabrizio Scotti, Renata del Grosso, Davide Romano, Francesco Semeraro, Paolo Vinciguerra, Ciro Costagliola, Mario R. Romano

“…The macula may develop cytotoxic oedema when the primary lesion and fluid accumulation occur in the parenchymatous cells (intracellular oedema) or vasogenic oedema when the primary defect occurs in the blood-retinal barrier and leads to extracellular fluid accumulation (extracellular oedema). …”
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Stability Analysis and Clinic Phenomenon Simulation of a Fractional-Order HBV Infection Model by Yongmei Su, Sinuo Liu, Shurui Song, Xiaoke Li, Yongan Ye

“…The basic reproductive number R0 and the cytotoxic T lymphocytes’ immune-response reproductive number R1 were derived. …”
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Tumor-Induced Local and Systemic Impact on Blood Vessel Function by J. Cedervall, A. Dimberg, A-K. Olsson

“…In addition, leukocytes, such as cytotoxic T-cells, have to travel across the vessel wall to enter the tumor tissue where they contribute to killing of cancer cells. …”
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Modulation of nitric oxide synthase activity in macrophages by P. G. Jorens, K. E. Matthys, H. Bult

“…NO is a major effector molecule of the anti-microbial and cytotoxic activity of rodent macrophages against certain micro-organisms and tumour cells, respectively. …”
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Potential Use of Bisphosphonates in Invasive Extramammary Paget’s Disease: An Immunohistochemical Investigation by Taku Fujimura, Sadanori Furudate, Yumi Kambayashi, Setsuya Aiba

“…In this study, we employed immunohistochemical staining for immunosuppressive macrophages and cytotoxic T cells in the lesional skin of patients with noninvasive EMPD and those with invasive EMPD.…”
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Alpha-Hemoglobin-Stabilizing Protein: An Erythroid Molecular Chaperone by Maria Emília Favero, Fernando Ferreira Costa

“…Evidence strongly suggests that AHSP participates in hemoglobin synthesis and may act to neutralize the cytotoxic effects of excess free alpha-globin subunits that accumulate both in normal and beta-thalassemic erythroid precursor cells. …”
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Oncolytic influenza virus enhances killing effect of gemcitabine against pancreatic cancer cells by MENG Zihe, MENG Zihe, XU Yongru, DENG Zhaoda

“…At the cellular level， the viruses demonstrated a significant selective cytotoxic effect on Panc02， PANC-1， SW1990， and BxPC-3 cells under the conditions of 48 h post-infection and MOI=3.0， when compared to 48 h post-infection and MOI=0 （P<0.01）. …”
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Human head and neck cancer cell lines response to cold atmospheric plasma activated media is affected by the chemistry of culture media by Viviana di Giacomo, Marwa Balaha, Asia Pece, Ilaria Cela, Gianluca Fulgenzi, Giovanna Orsini, Tatiana Spadoni, Tirtha Raj Acharya, Nagendra Kumar Kaushik, Eun Ha Choi, Monica Rapino, Mariangela Mazzone, Gabriella Mincione, Gianluca Sala, Eloisa Sardella, Vittoria Perrotti

“…In addition, cytotoxic effects were also observed on HNC, two bladder cancer models and one breast cancer cell line when considering PTL, paving the way for their application into a clinical setting.…”
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