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The novel CD16A/anti-CD3 bifunctional protein, eCD16A/anti-CD3-BFP, redirects T cell cytotoxicity toward antibody-bound target cells
Published 2025-12-01“…Moreover, combining eCD16A/anti-CD3-BFP with anti-Epstein Barr virus (EBV) antibodies directed T cell cytotoxicity toward EBV-infected cells. These findings support further development of eCD16A/anti-CD3-BFP as a novel anti-cancer therapeutic to stimulate both innate and adaptive immunity.…”
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Novel silver nanoparticle-based biomaterials for combating Klebsiella pneumoniae biofilms
Published 2025-01-01Subjects: Get full text
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Quantitative analysis of povidone-iodine thin films by X-ray photoelectron spectroscopy and their physicochemical properties
Published 2017-06-01Subjects: Get full text
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Nymphaea pubescens Willd. extract and its flavonoid constituents vasodilate rat isolated pulmonary artery via NO-sGC-cGMP pathway
Published 2025-02-01Subjects: Get full text
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Subcytotoxic transepidermal delivery using low intensity cold atmospheric plasma
Published 2025-01-01Subjects: Get full text
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351
Structural, morphological and biological assessment of magnetic hydroxyapatite with superior hyperthermia potential for orthopedic applications
Published 2025-01-01Subjects: Get full text
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Tissue-friendly dentin treatments as a potential element in revascularization protocol (ex-vivo study)
Published 2025-02-01Subjects: Get full text
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Antiproliferative effect of hydroalcoholic brown propolis extract on tumor and non-tumor cells
Published 2025-01-01Subjects: Get full text
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Unravelling the outcome of L-glutaminase produced by Streptomyces sp. strain 5 M as an anti-neoplasm activity
Published 2025-01-01Subjects: Get full text
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IL-2-armored peptide-major histocompatibility class I bispecific antibodies redirect antiviral effector memory CD8+ T cells to induce potent anti-cancer cytotoxic activity with limited cytokine release
Published 2024-12-01“…A promising strategy is the use of peptide-major histocompatibility class I bispecific antibodies (pMHC-IgGs), which have emerged as an intriguing modality of TCE, based on their ability to selectively redirect highly reactive viral-specific effector memory cytotoxic CD8+ T cells to eliminate cancer cells. However, the relatively low frequency of these effector memory cells in human peripheral blood mononuclear cells (PBMCs) may hamper their redirection as effector cells for clinical applications. …”
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Valorization of local regional apple (Malus domestica Borkh.) cultivars versus commercial samples from Spain: Phenolic compounds by HPLC-MS/MS, cytotoxicity and biological potential on nitric oxide radicals and lipoxygenase inhibition
Published 2025-01-01“…Moreover, cellular viability was determined to perform MTT assay in HepG2 and HeLa cell lines to discard cytotoxicity. The results showed that procyanidin B2 (PB2), 3-caffeoylquinic acid, epicatechin and 4-hydroxy benzoic acid were the most abundant phenolic compounds. …”
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Isolation and Structural Identification of New Diol Esters of Okadaic Acid and Dinophysistoxin-1 from the Cultured <i>Prorocentrum lima</i>
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Anti-cancer and antimicrobial efficacy of ZnO nanoparticles synthesized via green route using Amaranthus dubius (Spleen Amaranth) leaves extract
Published 2025-12-01Subjects: Get full text
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Structural Modifications Reveal Dual Functions of the C-4 Carbonyl Group in the Fatty Acid Chain of Ipomoeassin F
Published 2025-01-01Subjects: Get full text
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Functionalization of selenium nanoparticles with olive polyphenols – impact on toxicity and antioxidative activity
Published 2023-12-01Subjects: Get full text
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