Role of aquaporins in brain water transport and edema by Yuyuan Li, Yining Wang, Xingda Huang, Hao Zhang, Youfei Guan, Xiaoyan Zhang

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A two-strain HIV-1 mathematical model to assess the effects of chemotherapy on disease parameters by Tinevimbo Shiri, Winston Garira, Senelani D. Musekwa

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Anticancer properties of Dillenia suffruticosa (Griffith Ex. Hook. F. & Thomsom) Martelli by Ika Rahayu, Susana Elya Sudrajat, Kris Herawan Timotius

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AI-based tumor-infiltrating lymphocyte scoring system for assessing HCC prognosis in patients undergoing liver resection by Zhiyang Chen, Tingting Xie, Shuting Chen, Zhenhui Li, Su Yao, Xuanjun Lu, Wenfeng He, Chao Tang, Dacheng Yang, Shaohua Li, Feng Shi, Huan Lin, Zipei Li, Anant Madabhushi, Xiangtian Zhao, Zaiyi Liu, Cheng Lu

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Comparative Analysis of Cytotoxicity and Odontogenic Differentiation of Novel Bioceramic Material on Human Dental Pulp Stem Cells – An In Vitro Study by G. R. Ishwarya Dhevi, Ponnudurai Arangannal, J Jeevarathan

“…This in vitro study aims to investigate the cytotoxicity and odontogenic differentiation of novel formulation DWPC with MTA Angelus, Biodentin (BD) and white portland cement (WPC) on human dental pulp stem cells (HDPSCs). …”
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Infiltration of CD8+ cytotoxic T-cells and expression of PD-1 and PD-L1 in ovarian clear cell carcinoma by Mengdi Fu, Huimei Zhou, Jiaxin Yang, Dongyan Cao, Zhen Yuan

“…There were more CD8+ cytotoxic T-cells in the adjacent nonneoplastic areas than in the tumor tissue samples (p < 0.001). …”
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Docking Studies, Synthesis, Characterization and Evaluation of Their Antioxidant and Cytotoxic Activities of Some Novel Isoxazole-Substituted 9-Anilinoacridine Derivatives by R. Kalirajan, M. H. Mohammed Rafick, S. Sankar, S. Jubie

“…The compounds were confirmed by physical and analytical data and screened for in vitro antioxidant activity by DPPH method, reducing power assay and total antioxidant capacity method. The cytotoxic activity of the compounds was also studied in HEp-2 cell line. …”
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Late Recovery from Severe Streptococcus pneumoniae Comatose Meningitis with Concomitant Diffuse Subcortical Cytotoxic Edema and Cortical Hypometabolism by Philippe Hantson, Thierry Duprez

“…Repeated brain magnetic resonance imaging (MRI) examination failed to demonstrate venous thrombosis, arterial ischemic stroke, or brain abscesses but revealed diffuse but reversible cortical cytotoxic edema at diffusion-weighted (DW) sequences. …”
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DNA Cleavage, Cytotoxic Activities, and Antimicrobial Studies of Ternary Copper(II) Complexes of Isoxazole Schiff Base and Heterocyclic Compounds by Vijay Kumar Chityala, K. Sathish Kumar, Ramesh Macha, Parthasarathy Tigulla, Shivaraj

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Development of Solid Nanosystem for Delivery of Chlorhexidine with Increased Antimicrobial Activity and Decreased Cytotoxicity: Characterization and In Vitro and In Ovo Toxicological Screening by Alexandra-Ioana Dănilă, Mihai Romînu, Krisztina Munteanu, Elena-Alina Moacă, Andreea Geamantan-Sîrbu, Iustin Olariu, Diana Marian, Teodora Olariu, Ioana-Cristina Talpoş-Niculescu, Raluca Mioara Cosoroabă, Ramona Popovici, Ştefania Dinu

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Synthesis and crystal structure of cytotoxic copper(II) complex with 1,10-phenanthroline-5,6-dione and isothiazole derivative by Yuliya A. Golubeva*, Ksenia S. Smirnova*, Lubov’ S. Klyushova**,1 Vladimir I. Potkin***, Elizaveta V. Lider

In Vitro Antiplasmodial, Cytotoxicity, and Antioxidant Activities of Lophira lanceolata (Ochnaceae): A Cameroonian Plant Commonly Used to Treat Malaria by Mounvera Abdel Azizi, Noumedem Anangmo Christelle Nadia, Yamssi Cedric, Gamago Nkadeu Guy-Armand, Ngouyamsa Nsapkain Aboubakar Sidiki, Tientcheu Noutong Jemimah Sandra, Tako Djimefo Alex Kevin, Vincent Khan Payne

“…We aimed this study at evaluating the in vitro antiplasmodial, antioxidant, and cytotoxicity activity of Lophira lanceolata extracts. …”
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Scoulerine promotes cytotoxicity and attenuates stemness in ovarian cancer by targeting PI3K/AKT/mTOR axis by Wang Fang, Zhang Yang, Pang Rui, Shi Shaohong, Wang Ran

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Association of Cytotoxic T Lymphocyte Antigen-4 Gene Polymorphisms with Psoriasis Vulgaris: A Case-Control Study in Turkish Population by Hatice Gül Dursun, Hüseyin Osman Yılmaz, Recep Dursun, Sevsen Kulaksızoğlu

“…Psoriasis is a common, chronic, and autoimmune skin disease in which dysregulation of immune cells, particularly T cells, is thought to play an important role in the pathogenesis. Cytotoxic T lymphocyte antigen-4 (CTLA-4) expressed only on activated T cells is an immunoregulatory molecule and plays a role in the pathogenesis of autoimmune disorders. …”
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Exploring Amanita muscaria (L.) Lam.: Cytotoxic, proapoptotic and antiferroptotic effect of acetone extract on JAR choriocarcinoma cell line by Milojević Sara D., Nikodijević Danijela D., Milutinović Milena G., Kosanić Marijana M., Petrović Nevena N., Jovanović-Krivokuća Milica G., Nacka-Aleksić Mirjana M.

“…The pharmaceutical industry has long focused on nature-derived biologically active compounds to address challenges in cancer treatment, particularly overcoming cancer cell resistance to programmed cell death, including apoptosis and ferroptosis. The cytotoxic effect of Amanita muscaria acetone extract on the JAR choriocarcinoma cell line was evaluated using MTT assay and analysis on two selected programmed cell death pathways. …”
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Synthesis and Characterization of New Palladium(II) Thiosemicarbazone Complexes and Their Cytotoxic Activity against Various Human Tumor Cell Lines by Wilfredo Hernández, Juan Paz, Fernando Carrasco, Abraham Vaisberg, Evgenia Spodine, Jorge Manzur, Lothar Hennig, Joachim Sieler, Steffen Blaurock, Lothar Beyer

“…Complex 6 shows a square planar geometry with two deprotonated ligands coordinated to PdII through the azomethine nitrogen and thione sulfur atoms in a cis arrangement. The in vitro cytotoxic activity measurements indicate that the palladium(II) complexes (IC50=0.01–9.87 μM) exhibited higher antiproliferative activity than their free ligands (IC50=23.48–70.86 and >250 μM) against different types of human tumor cell lines. …”
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On the Reaction of 2-Alkanoylnaphthohydroquinones with Hydroxylamine: Access to Cytotoxic 2-(Hydroxyamino)-1,4-naphthoquinone and Their 3-(Hydroxyimino)alkyl Analogous by Jaime A. Valderrama, Andrea Pérez-Herrera, Giulio G. Muccioli, Edmundo A. Venegas-Casanova, Rafael Jara-Aguilar, Pedro Buc Calderon, Julio Benites

“…In vitro screening of the substituted 1,4-naphthoquinones on a panel of cancer cells reveals moderate cytotoxic activities. Compound 19, 2-(hydroxyamino)-1,4-naphthoquinone, stands out by its anticancer potency against prostate cancer cells as shown by the lowest IC50 value (8.08 μM) and the best selectivity index (3.90).…”
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Highly oxygenated cyclohexenes from the leaves of Uvaria grandiflora Roxb. ex Hornem and their cytotoxic and α-glucosidase inhibitory activities by Virayu Suthiphasilp, Moses Egoh Betangah, Passakorn Teerapongpisan, Narawadee Rujanapun, Boonyanoot Chaiyosang, Sarawut Tontapha, Pakit Kumboonma, Brian O. Patrick, Raymond J. Andersen, Rawiwan Charoensup, Thidarat Duangyod, Phunrawie Promnart, Tharakorn Maneerat, Surat Laphookhieo

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Antibody-Dependent Cellular Cytotoxicity and NK Cell-Driven Immune Escape in HIV Infection: Implications for HIV Vaccine Development by Gamze Isitman, Ivan Stratov, Stephen J. Kent

“…It has long been recognised that cytotoxic T lymphocytes and neutralising antibodies readily select for immune escape HIV variants. …”
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Antibacterial and Cytotoxic Effects of Moringa oleifera (Moringa) and Azadirachta indica (Neem) Methanolic Extracts against Strains of Enterococcus faecalis by Lucía Arévalo-Híjar, Miguel Ángel Aguilar-Luis, Stefany Caballero-García, Néstor Gonzáles-Soto, Juana Del Valle-Mendoza

“…To evaluate antibacterial and cytotoxic effect of 2 methanolic extracts of Azadirachta indica and Moringa oleifera against strains of Enterococcus faecalis (ATCC 29212) in vitro. …”
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