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1881
Immune Modulation Effects of Lactobacillus casei Variety rhamnosus on Enterocytes and Intestinal Stem Cells in a 5-FU-Induced Mucositis Mouse Model
Published 2021-01-01“…Serum proinflammatory cytokines were significantly increased in the 5-FU group and were reversed by Lcr35. …”
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1882
Impact of Saccharomyces cerevisiae on the intestinal microbiota of dogs with antibiotic-induced dysbiosis
Published 2025-02-01“…Fecal swabs were collected on D0, 3, 11, 17, 20, 24, and 31 for microbiota analysis and blood on D0 and D24 for measurements of cytokines and cortisol.Results and discussionAt D0, two distinct microbiota profiles comprised of dogs from both groups, control and probiotic, were identified. …”
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1883
Immune modulation effects of curcumin in pristane-induced lupus mice
Published 2017-01-01“…We aimed to investigate the effects of curcumin on systemic lupus erythematosus (SLE) clinical manifestation, adaptive immune system components, proinflammatory cytokines, and autoantibody production in pristane-induced lupus mice. …”
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1884
Circulating Inflammatory Markers Are Inversely Associated with Heart Rate Variability Measures in Type 1 Diabetes
Published 2020-01-01“…Our aims were (1) to investigate biomarkers of the ongoing inflammation processes including cytokines, adhesion molecules, and chemokines and (2) to associate the findings with cardiovascular autonomic neuropathy in type 1 diabetes by measuring heart rate variability and cardiac vagal tone. …”
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1885
Peripheral Ulcerative Keratitis Associated with Autoimmune Disease: Pathogenesis and Treatment
Published 2017-01-01“…It is thought that circulating immune complexes and cytokines exert an important influence on the progression of this syndrome. …”
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1886
Fine Tuning Cell Migration by a Disintegrin and Metalloproteinases
Published 2017-01-01“…The different steps of immune cell, tissue cell, or cancer cell migration are tightly coordinated in time and place by growth factors, cytokines/chemokines, adhesion molecules, and receptors for these ligands. …”
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1887
Immunologic Regulation in Pregnancy: From Mechanism to Therapeutic Strategy for Immunomodulation
Published 2012-01-01“…In this paper, we illustrate the complex immunologic aspects of human reproduction in terms of the role of human leukocyte antigen (HLA), immune cells, cytokines and chemokines, and the balance of immunity in pregnancy. …”
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1888
Probiotics for Alleviating Alcoholic Liver Injury
Published 2019-01-01“…Probiotics enhance immune responses and reduce the levels of alcohol-induced inflammatory cytokines and reactive oxygen species (ROS) production in the liver and intestine. …”
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1889
Contribution of Neuroinflammation to the Pathogenesis of Cancer Cachexia
Published 2015-01-01“…In particular, functional changes are associated with increased hypothalamic concentration of proinflammatory cytokines, which suggests that neuroinflammation may represent the adaptive response of the brain to peripheral challenges, including tumor growth. …”
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1890
Diverse Roles of Macrophages in Atherosclerosis: From Inflammatory Biology to Biomarker Discovery
Published 2012-01-01“…Based on the central functions of macrophages in atherogenesis, cytokines, chemokines, enzymes, or microRNAs related to or produced by macrophages have become important clinical prognostic or diagnostic biomarkers. …”
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1891
Pathological Roles of Neutrophil-Mediated Inflammation in Asthma and Its Potential for Therapy as a Target
Published 2017-01-01“…Some patients display a neutrophil-dominant presentation and are characterized with low (or even absent) Th2 cytokines. In recent years, increasing evidence has also suggested that neutrophils play a key role in the development of certain subtypes of asthma. …”
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1892
Impact of Incretin-Based Therapies on Adipokines and Adiponectin
Published 2021-01-01“…Adipokines are a family of hormones and cytokines with both pro- and anti-inflammatory effects released into the circulation to exert their hormonal effects. …”
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1893
T-Cell Traffic Jam in Hodgkin's Lymphoma: Pathogenetic and Therapeutic Implications
Published 2011-01-01“…In this paper we will first evaluate the main processes modulating T-cell recruitment towards the lymph node microenvironment in HL, especially focusing on the role played by cytokines. We will then consider the most relevant mechanisms of immune escape exerted by neoplastic cells in order to evade antitumor immunity. …”
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1894
Neurobiology of Major Depressive Disorder
Published 2013-01-01“…Clinically, descriptive gene and protein expression analysis and genetic and functional studies revised here show that individual alterations of a complex signaling network, which includes the hypothalamic-pituitary-adrenal axis; the production of neurotrophins and growth factors; the expression of miRNAs; the production of proinflammatory cytokines; and, even, the abnormal delivery of gastrointestinal signaling peptides, are able to induce major mood alterations. …”
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1895
B Cells in Autoimmune Diseases
Published 2012-01-01“…The role of B cells in autoimmune diseases involves different cellular functions, including the well-established secretion of autoantibodies, autoantigen presentation and ensuing reciprocal interactions with T cells, secretion of inflammatory cytokines, and the generation of ectopic germinal centers. …”
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1896
The role of probiotics in ameliorating hyperuricemia: a review
Published 2025-01-01“…Probiotics ameliorate HUA through three pathways: competing with intestinal epithelial cells for purine absorption to decrease uric acid synthesis, inhibiting xanthine oxidase activity through modulation of inflammatory cytokines to reduce the conversion of purine to uric acid, as well as restoring and maintaining an orderly state of the gut microbiota to facilitate normal uric acid excretion. …”
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1897
Nonalcoholic Fatty Liver Disease: A Clinical Approach and Review
Published 2006-01-01“…The second hit involves multiple proinflammatory cytokines resulting in non-alcoholic steatohepatitis. …”
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1898
The Protective Effect of Anthocyanins Extracted from Aronia Melanocarpa Berry in Renal Ischemia-Reperfusion Injury in Mice
Published 2021-01-01“…The model resulted in renal dysfunction with high serum creatinine, blood urea nitrogen, and changes in proinflammatory cytokines (TNF-ɑ, IL-1β, IL-6, and MCP-1), renal oxidative stress (SOD, GSH, and CAT), lipid peroxidation (TBARS and MDA), and apoptosis (caspase-9). …”
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1899
Hei-Gu-Teng Zhuifenghuoluo Granule Modulates IL-12 Signal Pathway to Inhibit the Inflammatory Response in Rheumatoid Arthritis
Published 2018-01-01“…Moreover, IL-12R knockdown was able to interfere with the inhibition effects of HGT on the production of these cytokines. Our results confirmed the anti-inflammatory property of HGT, which was attributed to its inhibition on IL-12 signaling pathway.…”
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1900
Insulin-Attenuated Inflammatory Response of Dendritic Cells in Diabetes by Regulating RAGE-PKCβ1-IRS1-NF-κB Signal Pathway: A Study on the Anti-Inflammatory Mechanism of Insulin in...
Published 2020-01-01“…The fluctuations in the RNA levels of cytokines and chemokines were analyzed by quantitative RT-PCR. …”
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