Carrageenan-induced acute inflammation in the mouse air pouch synovial model. Role of tumour necrosis factor by M. Romano, R. Faggioni, M. Sironi, S. Sacco, B. Echtenacher, E. Di Santo, M. Salmona, P. Ghezzi

“…We used the mouse air pouch model of inflammation to study the interaction between cytokines, prostaglandin E2 (PGE2) and cell migration during the various phases of acute local inflammation induced by carrageenan. …”
Get full text

NADPH Oxidase Inhibitor Apocynin Attenuates PCB153-Induced Thyroid Injury in Rats by Ablikim Abliz, Chen Chen, Wenhong Deng, Weixing Wang, Rongze Sun

“…Oxidative stress and inflammatory cytokines were detected. The following results were reduced after apocynin treatment: (1) serum thyroid hormone, (2) thyroid pathological injuries, (3) thyroid MDA, (4) thyroid ultrastructural change, (5) serum inflammatory cytokines, and (6) thyroid expression of NOX2, 8-OHdG, and NF-κB. …”
Get full text

Health benefits of algae and marine-derived bioactive metabolites for modulating ulcerative colitis symptoms by Najmeh Oliyaei, Saghar Zekri, Aida Iraji, Alireza Oliyaei, Romina Tanideh, Nadiar M. Mussin, Amin Tamadon, Nader Tanideh

“…This review focused on the pathology of ulcerative colitis, pathogenesis and key inflammatory pathways, and the role of algae and marine-based metabolites for reduction of ulcerative colitis signs via alleviating the inflammation cytokines secretion, and improving the barrier function and gut microbiota.…”
Get full text

Effects of IQW and IRW on Inflammation and Gut Microbiota in ETEC-Induced Diarrhea by Naiyuan Liu, Lingsi Zhou, Jun Fang, Hongmei Jiang, Gang Liu

“…The inflammatory reaction was analyzed via inflammatory cytokines (i.e., TNF-α, IL-1β, IL-6, and IL-10) using the enzyme-linked immunosorbent assay (ELISA). …”
Get full text

Dairy Foods in a Moderate Energy Restricted Diet Do Not Enhance Central Fat, Weight, and Intra-Abdominal Adipose Tissue Losses nor Reduce Adipocyte Size or Inflammatory Markers in... by Marta D. Van Loan, Nancy L. Keim, Sean H. Adams, Elaine Souza, Leslie R. Woodhouse, Anthony Thomas, Megan Witbracht, Erik R. Gertz, Brian Piccolo, Andrew A. Bremer, Michael Spurlock

“…Weight, fat, intra-abdominal adipose tissue (IAAT), subcutaneous adipose tissue (SAT) macrophage number, SAT inflammatory gene expression, and circulating cytokines were measured. Results. No diet differences were observed in weight, fat, or IAAT loss; nor SAT mRNA expression of inflammation, circulating cytokines, fasting lipids, glucose, or insulin. …”
Get full text

Behçet Disease-Like Symptoms with a Novel COPA Mutation by E. Anderson, J. Hatch, J. Cardinal, D. Langguth, D. Coman

“…These mutations lead to endoplasmic reticulum stress and autoimmune response with upregulation of Th17 cytokines. The clinical phenotype of COPA syndrome primarily comprised pulmonary disease, arthritis, and renal disease secondary to immune dysregulation, with onset of symptoms commonly in the first decade of life. …”
Get full text

The Role of Adipose Tissue and Adipokines in Obesity-Related Inflammatory Diseases by Carmela Rita Balistreri, Calogero Caruso, Giuseppina Candore

“…As consequence, increased circulating levels of proinflammatory cytokines, hormone-like molecules, and other inflammatory markers are induced. …”
Get full text

Combined delivery of IL12 and an IL18 mutant without IL18BP-binding activity by an adenoviral vector enhances tumor specific immunity by Yan Cheng, Renjie Luo, Erguang Li

“…Abstract Cytokines play pivotal roles in anticancer immune response. …”
Get full text

Magnesium Lithospermate B Downregulates the Levels of Blood Pressure, Inflammation, and Oxidative Stress in Pregnant Rats with Hypertension by Kaixiang Xu, Xiaohong Zang, Mian Peng, Qian Zhao, Binbin Lin

“…The activities of inflammatory cytokines were highly increased in serum and placental tissues of PIH rats, while cotreatment with MLB partially reversed the activities of these cytokines. …”
Get full text

Pengaruh Kombinasi Metformin dan Ekstrak Kunyit terhadap Kadar High Density Lipoprotein, Interleukin-6 dan Tumor Necrosis Factor-a by Fathia Kesuma Dinanti, Sri Priyantini Mulyani, Chodidjah - -

“…A  decrease in high-density lipoprotein (HDL) happens in type 2 diabetes mellitus. The cytokines TNFa and IL-6 are proinflammatory cytokines that are elevated in the blood in many patients with DM. …”
Get full text

Inflamm-Aging Is Associated with Lower Plasma PTX3 Concentrations and an Impaired Capacity of PBMCs to Express hTERT following LPS Stimulation by Aaron L. Slusher, Tiffany M. Zúñiga, Edmund O. Acevedo

“…Age-related elevations in proinflammatory cytokines, known as inflamm-aging, are associated with shorter immune cell telomere lengths. …”
Get full text

Rectal application of a highly osmolar personal lubricant in a macaque model induces acute cytotoxicity but does not increase risk of SHIV infection. by Sundaram A Vishwanathan, Monica R Morris, Richard J Wolitski, Wei Luo, Charles E Rose, Dianna M Blau, Theodros Tsegaye, Sherif R Zaki, David A Garber, Leecresia T Jenkins, Tara C Henning, Dorothy L Patton, R Michael Hendry, Janet M McNicholl, Ellen N Kersh

“…<h4>Results</h4>Lubricant increased pro-inflammatory cytokines and tissue sloughing while control buffer (phosphate buffered saline; PBS) did not. …”
Get full text

Anti-Inflammatory Effects of Aster incisus through the Inhibition of NF-κB, MAPK, and Akt Pathways in LPS-Stimulated RAW 264.7 Macrophages by Daniel Ngabire, Yeong-Ae Seong, Maheshkumar Prakash Patil, Irvine Niyonizigiye, Yong Bae Seo, Gun-Do Kim

“…Aster incisus also reduced significantly the production of inflammation-related enzymes (iNOS, Cox-2) and cytokines (TNFα, IL-1β, and IL-6) and the gene expression of the proinflammatory cytokines. …”
Get full text

Siglec-E augments adipose tissue inflammation by modulating TRAF3 signaling and monocytic myeloid-derived suppressor cells during obesity by Ahmed Rakib, Mousumi Mandal, Md Abdullah Al Mamun, Sonia Kiran, Nelufar Yasmen, Lexiao Li, Daniel M. Collier, Jianxiong Jiang, Frank Park, Udai P. Singh

“…We analyzed the changes in immune phenotypes, inflammatory response, adipogenesis, and levels of cytokines and chemokines after HFD and ND feeding.ResultsHFD consumption significantly increased the body weight and blood glucose levels in siglec-E KO mice relative to those of WT mice. …”
Get full text

Noncanonical IFN Signaling, Steroids, and STATs: A Probable Role of V-ATPase by Howard M. Johnson, Ezra Noon-Song, Chulbul M. Ahmed

“…Signaling of nuclear receptors such as those of estrogen and dihydrotestosterone provides templates for making sense of the specificity of gene activation by closely related cytokines, which has implications for lymphocyte phenotypes.…”
Get full text

Beyond Fat Mass: Exploring the Role of Adipokines in Rheumatic Diseases by Morena Scotece, Javier Conde, Rodolfo Gómez, Veronica López, Francisca Lago, Juan Jesus Gómez-Reino, Oreste Gualillo

“…The cloning of leptin in 1994 by Zhang et al. introduced a novel concept about white adipose tissue (WAT) as a very dynamic organ that releases a plethora of immune and inflammatory mediators, such as adipokines and cytokines, which are involved in multiple diseases. …”
Get full text

The Role of MIF in Type 1 and Type 2 Diabetes Mellitus by Yuriko I. Sánchez-Zamora, Miriam Rodriguez-Sosa

“…Both processes are orchestrated by inflammatory cytokines, including the macrophage migration inhibitory factor (MIF). …”
Get full text

Intranasal delivery of hMSC-derived supernatant for treatment of ischemic stroke by inhibiting the pro-inflammatory polarization of neutrophils by Yixiang Jiang, Ning Wang, Jingyi Liu, Haoran Ren, Wenkang Jiang, Yanting Lei, Xidan Fu, Miao Hao, Xiujuan Lang, Yumei Liu, Xijun Liu, Rui Li, Hulun Li

“…Flow cytometry and qPCR evaluated the expression of immune cells and cytokines in the CNS and peripheral immune organs. …”
Get full text

Association of Plasma Circulatory Markers, Chlamydia pneumoniae, and High Sensitive C-Reactive Protein in Coronary Artery Disease Patients of India by Hem Chandra Jha, Pragya Srivastava, Rakesh Sarkar, Jagdish Prasad, Aruna Singh Mittal

“…Suggesting the important role of these cytokines in progression of CAD.…”
Get full text

Quantitative profiling of the vaginal microbiota improves resolution of the microbiota-immune axis by Eric Armstrong, Rachel Liu, James Pollock, Sanja Huibner, Suji Udayakumar, Erastus Irungu, Pauline Ngurukiri, Peter Muthoga, Wendy Adhiambo, Sergey Yegorov, Joshua Kimani, Tara Beattie, Bryan Coburn, Rupert Kaul

“…Bacterial load was also positively associated with proinflammatory cytokines, such as IL-1α, and negatively associated with chemokines, such as IP-10. …”
Get full text