Studies on the Interleukin-10 Gene in Animal Models of Colitis by Hugh J Freeman

“…Cytokines play a role in the inflammatory process in colitis and may have therapeutic potential. …”
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Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function by Inssaf Berkiks, Inssaf Berkiks, Nada Abdel Aziz, Nada Abdel Aziz, Nada Abdel Aziz, Blessing Moses, Blessing Moses, Tiroyaone Brombacher, Tiroyaone Brombacher, Frank Brombacher, Frank Brombacher

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Cross-Talk between PPARγ and Insulin Signaling and Modulation of Insulin Sensitivity by Anna Leonardini, Luigi Laviola, Sebastio Perrini, Annalisa Natalicchio, Francesco Giorgino

“…Finally, adipose tissue produces several cytokines that regulate energy homeostasis, lipid and glucose metabolism. …”
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Probiotics alleviate painful diabetic neuropathy by modulating the microbiota–gut–nerve axis in rats by Ye Jiang, Jing Yang, Min Wei, Jiayin Shou, Shixiong Shen, Zhuoying Yu, Zixian Zhang, Jie Cai, Yanhan Lyu, Dongsheng Yang, Yongzheng Han, Jinpiao Zhu, Zhigang Liu, Daqing Ma, Guo-gang Xing, Min Li

“…Probiotics administration effectively attenuated intestinal barrier impairment, reduced serum lipopolysaccharide and proinflammatory cytokines, and mitigated disruptions in the blood-nerve barrier. …”
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From Placenta to Polycystic Ovarian Syndrome: The Role of Adipokines by Chiara Sartori, Pietro Lazzeroni, Silvia Merli, Viviana Dora Patianna, Francesca Viaroli, Francesca Cirillo, Sergio Amarri, Maria Elisabeth Street

“…Adipokines are cytokines produced mainly by adipose tissue, besides many other tissues such as placenta, ovaries, peripheral-blood mononuclear cells, liver, muscle, kidney, heart, and bone marrow. …”
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Effects of ALA-PDT on the murine footpad model of Fonsecaea monophora infection and its related mechanisms in vivo by Xuelin Wu, Wenyi Chen, Muhammad Danish Yaqoob, Kangxing Liu, Yanqing Hu, Yan Lu, Yongxuan Hu

“…Furthermore, PDT upregulated the anti-inflammatory cytokines IL-4 and IL-10 while downregulated the pro-inflammatory cytokines TNF-α and GM-CSF in mouse serum. …”
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IL-1β and IL-6 Are Highly Expressed in RF+IgE+ Systemic Lupus Erythematous Subtype by Yongkang Wu, Bei Cai, Junlong Zhang, Beilei Shen, Zhuochun Huang, Chunyu Tan, Carla C. Baan, Lanlan Wang

“…To better categorize SLE subtypes, we determined the dominant cytokines based on familial SLE patients. Methods. …”
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PD-L1 knockout or ZG16 overexpression inhibits PDAC progression and modulates TAM polarization by Hui Meng, Manman Nan, Yizhen Li, Yi Ding, Xiaokun Fang, Weiqian Ma, Mingzhi Zhang

“…Meanwhile, we observed a reduction in the M2 marker CD206+, upregulation of immune activation-related cytokines/chemokines, and a decrease in immunosuppressive cytokines and tumor angiogenesis factors. …”
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Central Mechanisms of Abnormal Sympathoexcitation in Chronic Heart Failure by Takuya Kishi, Yoshitaka Hirooka

“…Recently, the abnormalities in the central regulation of sympathetic nerve activity mediated by brain renin angiotensin system-oxidative stress axis and/or proinflammatory cytokines have been focused. Central renin angiotensin system, proinflammatory cytokines, and the interaction between them have been determined as the target of the sympathoinhibitory treatment in experimental animal models with chronic heart failure. …”
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Inflammatory Mechanisms of Idiopathic Epiretinal Membrane Formation by Malav Joshi, Shivi Agrawal, John Byron Christoforidis

“…The cellular constituents of iERMs are thought to consist of glial cells, fibroblasts, hyalocytes, etc. that, in concert with cytokines and growth factors present in the vitreous, lead to iERM formation. …”
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3-MA attenuates collagen-induced arthritis in vivo via anti-inflammatory effect and autophagy inhibition by Chong Feng, Zi-rou Wang, Chen-yu Li, Xiang-yu Zhang, Xin-xing Wang

“…Serum assay showed that 3-MA significantly reduced inflammatory cytokines levels, suppressed oxidative levels and bone resorption cytokines. …”
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Differential regulation of metalloproteinase production, proliferation and chemotaxis of human lung fibroblasts by PDGF, Interleukin-1β and TNF-α by Masahiro Sasaki, Masayuki Kashima, Takefumi Ito, Akiko Watanabe, Noriko Izumiyama, Masaaki Sano, Manabu Kagaya, Takanobu Shioya, Mamoru Miura

“…Fibroblast migration, proliferation, extracellular matrix protein synthesis and degradation,all of which play important roles in inflammation, are them selves induced by various growth factors and cytokines. Less is known about the interaction of these substances on lung fibroblast function in pulmonary fibrosis.…”
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Understanding the Immune System in Fetal Protection and Maternal Infections during Pregnancy by Tarique Hussain, Ghulam Murtaza, Dildar Hussain Kalhoro, Muhammad Saleem Kalhoro, Yulong Yin, Muhammad Ismail Chughtai, Bie Tan, Anjaleena Yaseen, Zia Ur Rehman

“…The trophoblast cells not only give an active response against external stimuli but are also involved in secreting most of the cytokines. These cells have an essential function in fetal acceptance or fetal rejection. …”
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Inflammation and Hypertension: Are There Regional Differences? by Patricio López-Jaramillo, Carlos Velandia-Carrillo, Julie Álvarez-Camacho, Daniel Dylan Cohen, Tatiana Sánchez-Solano, Gabriela Castillo-López

“…The concentration of proinflammatory cytokines is higher in the Latin American population than that reported in developed countries, suggesting a higher susceptibility to develop systemic low-degree inflammation at a given level of abdominal obesity. …”
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Effects of a Combination of Thyme and Oregano Essential Oils on TNBS-Induced Colitis in Mice by Alexandra Bukovská, Štefan Cikoš, Štefan Juhás, Gabriela Il’ková, Pavol Rehák, Juraj Koppel

“…Treatment of colitic animals with the essential oils decreased the mRNA levels of pro-inflammatory cytokines IL-1β, IL-6, GM-CSF, and TNFα, especially after application of the medium dose. …”
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Celecoxib Improves Host Defense through Prostaglandin Inhibition during Histoplasma capsulatum Infection by Priscilla Aparecida Tartari Pereira, Bruno Caetano Trindade, Adriana Secatto, Roberto Nicolete, Camila Peres-Buzalaf, Simone Gusmão Ramos, Ruxana Sadikot, Claudia da Silva Bitencourt, Lúcia Helena Faccioli

“…Prostaglandins act as mediators of inflammation and, similar to cytokines, function as immune modulators during innate and adaptive immune responses. …”
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Improvement of Lumbar Bone Mass after Infliximab Therapy in Crohn’s Disease Patients by Marina Mauro, Vladimir Radovic, David Armstrong

“…Elevated proinflammatory cytokines, such as tumour necrosis factor-alpha (TNFα), have been implicated in the pathogenesis of bone resorption.…”
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The Potential Proallergenic Activity of Tranzschelia pruni-spinosae and Phragmidium rubi-idaei in vitro Studies by Sztandera-Tymoczek M, Wdowiak-Wróbel S, Świderska U, Palusińska-Szysz M, Szuster-Ciesielska A

“…The increase in these cytokines and the elevated ROS production were linked to the disruption of epithelial cell junctions.Conclusion: The findings suggest the potential of T. pruni-spinosae and P. rubi-idaei extracts to collectively disrupt the epithelial barrier in the upper and lower respiratory tract by inducing proinflammatory cytokines and the production of reactive oxygen species and metalloproteinases. …”
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Recurrence of hepatitis C after liver transplantation is associated with increased systemic IL-10 levels by Patricia A. Sheiner, Sander S. Florman, Sukru Emre, Thomas Fishbein, Myron E. Schwartz, Charles M. Miller, Peter Boros

“…Background: Recurrence of hepatitis C after liver transplantation is an almost universal occurrence. T-cell derived cytokines have an important role in the development of liver damage associated with chronic hepatitis C, their post-transplant levels, however, have not been correlated with histologic recurrence of the disease.…”
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Exercise Induced Adipokine Changes and the Metabolic Syndrome by Saeid Golbidi, Ismail Laher

“…Obesity is characterized by the deposition of adipose tissue in various parts of the body; it is now evident that adipose tissue also acts as an endocrine organ capable of secreting many cytokines that are though to be involved in the pathophysiology of obesity, insulin resistance, and metabolic syndrome. …”
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