Effects and Mechanisms of Silibinin on Influenza A/H1N1 Pathogenesis in a Mouse Model by Mohsen Keshavarz, Mohsen Ghorbani, Forough Shamsizadeh, Haideh Namdari, Vahid Salimi, Farhad Rezaei

“…The present study aimed to determine the inflammatory and anti-inflammatory cytokine secretion patterns in mice before and after silibinin treatment. …”
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Effects of female sexual chemosignals on mucosal immunity in BALB/c and C57BL/6 male mice by G. V. Kontsevaya, E. A. Litvinova, M. P. Moshkin

“…The immune response to immunogenic stimuli depends on various factors like cytokine context, way of entry, and immune status of the organism. …”
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Phenotype and Function of CD25-Expressing B Lymphocytes Isolated from Human Umbilical Cord Blood by Sylvie Amu, Mikael Brisslert

“…Phenotype and function of these B-cell populations were compared using flow cytometry, proliferation, cytokine production, and immunoglobulin secretion. …”
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Advancing Multiple Myeloma Immunotherapy: A Review of Chimeric Antigen Receptor T-Cell and Bispecific T-Cell Engagers Cell Therapies in Revolutionizing Treatment by Rahul Navab, Pragyat Futela, Verkha Kumari, Jayesh Valecha, Ramansh Bandhu Gupta, Rohit Jain

“…Despite their successes, these therapies come with unique challenges and adverse effects, such as cytokine release syndrome (CRS) and neurotoxicity. …”
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NOD Dendritic Cells Stimulated with Lactobacilli Preferentially Produce IL-10 versus IL-12 and Decrease Diabetes Incidence by Jean N. Manirarora, Sarah A. Parnell, Yoon-Hyeon Hu, Michele M. Kosiewicz, Pascale Alard

“…These data indicated that L. casei can induce NOD DCs to develop a more tolerogenic phenotype via production of the anti-inflammatory cytokine, IL-10. Evaluation of the relative production of IL-10 and IL-12 by DCs may be a very useful means of identifying agents that have therapeutic potential.…”
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The Consequences of Chorioamnionitis: Preterm Birth and Effects on Development by Robert Galinsky, Graeme R. Polglase, Stuart B. Hooper, M. Jane Black, Timothy J. M. Moss

“…The fetal inflammatory response syndrome (FIRS) is defined by increased systemic inflammatory cytokine concentrations, funisitis, and fetal vasculitis. …”
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Nucleotide-Binding Oligomerization Domain-1 and -2 Play No Role in Controlling Brucella abortus Infection in Mice by Fernanda S. Oliveira, Natalia B. Carvalho, Dario S. Zamboni, Sergio C. Oliveira

“…Similar reduction on cytokine synthesis was not observed for IL-12 and IL-6. …”
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Immunotherapeutic Potential of Lactobacillus Species as Immune Checkpoint Inhibitors in Cancer Immunotherapy by Renukadevi J, Sam Helinto J, Prena D

“…These interactions promote cytokine production, enhance CD8+ T-cell activity, and improve the gut barrier. …”
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A pair of promising immune checkpoints PSGL-1 and VISTA from immunotolerance to immunotherapy by Manqing Peng, Xiaofang Lu, Junshuang Guo, Xiangli Yin, Jing Zhang, Xin Li, Yizhou Zou

“…VISTA functions both as a ligand on myeloid cells, where it regulates cytokine production, chemotaxis, and phagocytosis while promoting their differentiation into a tolerogenic phenotype and as a receptor on T cells, where it contributes to T cell quiescence. …”
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The TIR Domain Containing Locus of Enterococcus faecalis Is Predominant among Urinary Tract Infection Isolates and Downregulates Host Inflammatory Response by Thomas Daniel Kraemer, Orlando Daniel Quintanar Haro, Eugen Domann, Trinad Chakraborty, Svetlin Tchatalbachev

“…Infection of mouse RAW264.7 macrophages with a tcpF knock-out mutant led to elevated cytokine response compared to the isogenic wild type E. faecalis strain. …”
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Acetylation Modification Improves Immunoregulatory Effect of Polysaccharide from Seeds of Plantago asiatica L. by Le-Ming Jiang, Shao-Ping Nie, Dan-Fei Huang, Zhi-Hong Fu, Ming-Yong Xie

“…The results showed that Ac-PLCPs with degree of substitution (DS) from 0.06 to 0.1 could not only stimulate the expression of surface molecules major histocompatibility complex class II (MHC II), cluster of differentiation 86 (CD86), and CD80 on DCs (P<0.01) but also increase the secretion of cytokine IL-12p70 (P<0.01). The endocytosis activity of DCs was attenuated by Ac-PLCPs treatment (P<0.01), while the mRNA expressions of chemokine receptors CCR7 and CXCR4 in DCs were significantly increased (P<0.01). …”
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Visfatin/Nampt: An Adipokine with Cardiovascular Impact by Tania Romacho, Carlos F. Sánchez-Ferrer, Concepción Peiró

“…Visfatin/Nampt effects on cytokine and chemokine secretion, macrophage survival, leukocyte recruitment by endothelial cells, vascular smooth muscle inflammation and plaque destabilization make of this adipokine an active factor in the development and progression of atherosclerosis. …”
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Biocompatible Peritoneal Dialysis Fluids: Clinical Outcomes by Yeoungjee Cho, Sunil V. Badve, Carmel M. Hawley, Kathryn Wiggins, David W. Johnson

“…Several preclinical studies have demonstrated their benefit in terms of improvement in host cell defence, peritoneal membrane integrity, and cytokine profile. This paper aims to review randomised controlled trials assessing the use of biocompatible PD fluids and their effect on clinical outcomes.…”
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Therapeutic effects of epigallocatechin and epigallocatechin gallate on the allergic reaction of αs1-casein sensitized mice by Qianqian Zhang, Xiaofeng Yu, Linghan Tian, Yanjun Cong, Linfeng Li

“…The main evaluation indexes used were levels of mast cell proteases, histamine, and specific antibody immunoglobulin E (IgE), as well as cytokine secretion and pathological observation. The results showed that both EGC and EGCG significantly reduced levels of mast cell protease, histamine, specific IgE antibodies, and Th2 cytokines in allergic mice. …”
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Peptidoglycan recognition protein PGRP-5 is involved in immune defence and neuro-behavioral disorders in zebrafish embryos. by Xi Li, Guanghua Xiong, Manni Luo, Siwan Mao, Ruiying Zhang, Ziwei Meng, Juan Li, Xinjun Liao

“…Moreover, knock-down DrPGRP-5 could significantly reduce the pro-inflammatory cytokines such as TNF-α, IL-1β and IL-6, but increased the expression of anti-inflammatory cytokine TGF-β. …”
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Variational graph autoencoder for reconstructed transcriptomic data associated with NLRP3 mediated pyroptosis in periodontitis by Pradeep K. Yadalam, Prabhu Manickam Natarajan, Carlos M. Ardila

“…Abstract The NLRP3 inflammasome, regulated by TLR4, plays a pivotal role in periodontitis by mediating inflammatory cytokine release and bone loss induced by Porphyromonas gingivalis. …”
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Blocking Interleukin-33 Alleviates the Joint Inflammation and Inhibits the Development of Collagen-Induced Arthritis in Mice by Yan Li, Yeqin Fu, Huan Chen, Xiaojin Liu, Mingcai Li

“…Interleukin-33 (IL-33) is a proinflammatory cytokine which is highly expressed in the synovium of RA patients and the joints of mice with collagen-induced arthritis (CIA) and exacerbates CIA in mice. …”
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Injectable hyaluronic acid-based hydrogel niches to create localized and time-controlled therapy delivery by Veronica Torresan, Alessandro Gandin, Paolo Contessotto, Francesca Zanconato, Giovanna Brusatin

“…Additionally, we incorporated thiol-modified heparin into the formulation, which provides specific binding sites for cytokines. Our results indicate that heparin incorporation can delay cytokine release, while the release of nanocarriers can be regulated by adjusting the crosslinking degree. …”
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Interleukin-15 and Tumor Necrosis Factor-α in Iraqi Patients with Alopecia Areata by Zainab A. Kamil, Galawish A. Abdullah, Haider Hashim Zalzala

“…Most evidence supports the hypothesis that it is disease of the hair follicle of autoimmune nature mediated by T-cells, with important cytokine role. Objective of the Study. The objective of this study is to study the association and changes in serum levels of interleukin-15 (IL-15) and tumor necrosis factor-α (TNF-α) in patients with AA in relation to the type, activity, and disease duration. …”
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Shielding the Gut: Ghrelin and Ferrostatin-1’s Protective Role Against Sepsis-Induced Intestinal Ferroptosis by Qiliang Hou, Zhimin Dou, Lei Zhu, Bin Li

“…Our comprehensive methodology encompasses histopathological evaluations, cytokine profiling, oxidative stress assays, and detailed analyses of ferroptosis indicators to thoroughly assess the interventions’ efficacy. …”
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