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861
Expression Profiling of Transglutaminase 2 and Inflammatory Host Response in Aspergillus Fumigatus After Treatment with Curcuma Extracts
Published 2021-12-01“…We also screened the levels of cytokines with and without the treatment to confirm the activity. …”
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862
Immunomodulating activities of a natural α1 -acid glycoprotein and its carbohydrate chains attached to the Protein-Free Polymer
Published 1998-01-01“…Stimulation of the LPS-induced proinflammatory cytokine production by m ononuclear cells treated with both natural and pseudo-AGP has been also demonstrated. …”
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863
The Roles of circRNAs in Intervertebral Disc Degeneration: Inflammation, Extracellular Matrix Metabolism, and Apoptosis
Published 2022-01-01“…Circular RNAs (circRNAs), as a kind of noncoding RNA (ncRNA), participate in the regulation of genetic transcription and translation and further affect the expression of inflammatory cytokine, metabolism of extracellular matrix (ECM), the proliferation and apoptosis of cells, etc. …”
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864
Tag7 (PGLYRP1) Can Induce an Emergence of the CD3+CD4+CD25+CD127+ Cells with Antitumor Activity
Published 2018-01-01“…Our data suggest that this subpopulation of cells is identical to the CD4+CD25+ lymphocytes, which are activated in the leukocyte pool by the IL-2 cytokine.…”
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865
Studies on the Anti-Inflammatory Effect and Its Mechanisms of Sophoridine
Published 2014-01-01“…It is demonstrated that sophoridine’s anti-inflammatory effect was due to its ability to inhibit the production of cytokine and inflammatory mediators.…”
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866
The effects of the ketone body ?-hydroxybutyrate on the neuronal transcriptome
Published 2025-02-01“…We identified significantly altered (p<0.05) pathways associated with inflammation and immunity such as “regulation of proinflammatory cytokine production” and “modulation of inflammatory responses.” …”
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867
Overview of (1→3)-β-D-glucan immunobiology
Published 1997-01-01“…Following receptor binding, glucan modulates macrophage cytokine expression. Here we review the chemistry, immunobiology and toxicity of (1→3)-β-D-glucans and how it may relate to effects caused by inhalation.…”
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868
Genetic Factors in Animal Models of Intestinal Inflammation
Published 1995-01-01“…The dominant role of genetic background in induction of intestinal inflammation is further documented by spontaneous colitis which develops in spontaneously mutant mice, cotton-top tamarins, human leukocyte antigen-B27/ β2 microglobulin transgenic rats and mice with targeted deletions of certain immunoregulatory cytokine and T lymphocyte genes. Identification of the immunological mechanisms of host genetic susceptibility and the genetic basis of spontaneous colitis should provide new insights into the pathogenesis of human inflammatory bowel disease.…”
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869
New Antibody Conjugates in Cancer Therapy
Published 2010-01-01“…The Dock-and-Lock platform technology has contributed to the design and the evaluation of complex antibody-cytokine and antibody-toxin conjugates. This review describes the advances made in these areas, with illustrations taken from advances made in the authors' institutions.…”
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870
A randomized, placebo-controlled trial of the BTK inhibitor zanubrutinib in hospitalized patients with COVID-19 respiratory distress: immune biomarker and clinical findings
Published 2025-01-01“…BackgroundCytokine release triggered by a hyperactive immune response is thought to contribute to severe acute respiratory syndrome coronavirus 2019 (SARS-CoV-2)–related respiratory failure. …”
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871
The mcpC mutant of Salmonella enteritidis exhibits attenuation and confers both immunogenicity and protective efficacy in mice
Published 2025-02-01“…Immunization with ΔmcpC induced the production of specific IgG and SIgA antibodies, enhanced lymphocyte proliferation, upregulated cytokine expression, and achieved a 100% survival rate in immunized mice. …”
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872
Comparison of Properties of Stem Cells Isolated from Adipose Tissue and Lipomas in Dogs
Published 2019-01-01“…Results from cytokine arrays including 20 cytokines showed no significant differences between CM of LDSCs and that of ADSCs. …”
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873
Monocyte STAT1 phosphorylation and treatment response of JAK inhibitors in chronic nonbacterial osteomyelitis
Published 2025-01-01“…Clinical and immunological data were monitored in 4 patients with intractable CNO treated with adjunctive JAK inhibitors, focusing on scoring scales, imaging data, lymphocyte subsets, cytokine profiles, and pSTAT1 levels. Results Monocyte pSTAT1 expression after IFNγ stimulation was elevated at diagnosis or during active CNO, similar to levels observed in STAT1-GOF cases. …”
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874
Candidate approaches for predicting vitiligo recurrence: an effective model and biomarkers
Published 2025-02-01“…There were no significant differences in these cytokine levels between the two types of vitiligo. …”
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875
CD4 T cell depletion increases memory differentiation of endogenous and CAR T cells and enhances the efficacy of Super2 and IL-33-armored CAR T cells against solid tumors
Published 2025-02-01“…Here, we describe the intrinsic ability of CAR T cells to differentiate into memory T cells, the effect of cytokine armoring, and neoadjuvant CD4 depletion therapy on CAR and tumor-specific endogenous memory T cells.Methods TRP1-specific or NKG2D CAR T cells alone or with Super2+IL-33 (S233) armoring and/or CD4 depletion were evaluated in immunocompetent B16F10 melanoma or MC38 colon cell carcinoma models without preconditioning. …”
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876
The impact of cardiac complications on COVID-19 outcomes
Published 2024-08-01“…Possible mechanisms of cardiac damage are the high affinity of the SARS-CoV-2 adhesion protein to angiotensin-converting enzyme 2 receptors, cytokine storm, ischemia, inflammation, and acute respiratory distress syndrome. …”
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877
The Association of −330 Interleukin-2 Gene Polymorphism with Its Plasma Concentration in Iranian Multiple Sclerosis Patients
Published 2014-01-01“…Multiple sclerosis (MS) is a chronic neuroinflammatory demyelinating disease of the central nervous system. The cytokine genes are involved in autoimmune diseases such as MS. …”
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878
Tattooed human in vitro skin model for testing the biocompatibility of tattoo inks and healing progression after tattooing
Published 2025-01-01“…Biocompatibility including analysis of cytotoxicity, cytokine release, and gene expression patterns of proinflammatory cytokines, proliferation markers, growth factors and structural components was investigated over a period of 7 days. …”
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879
The Role of TOX in the Development of Innate Lymphoid Cells
Published 2015-01-01“…Innate lymphoid cells, classified according to transcription factor expression and cytokine secretion profiles, derive from common lymphoid progenitors in the bone marrow and require Notch signals for their development. …”
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880
Aging Adults and Seasonal Influenza: Does the Vitamin D Status (H)Arm the Body?
Published 2012-01-01“…Indeed, VitD has been shown to have significant effects on cytokine production and lymphocyte proliferation. Evidence that VitD affects clearance of selected pathogens is supported by epidemiological and clinical data, while its coadministration with influenza vaccine in mice enhanced both mucosal and systemic antibody responses. …”
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