IL-10 and socs3 Are Predictive Biomarkers of Dengue Hemorrhagic Fever by Lilian Karem Flores-Mendoza, Tania Estrada-Jiménez, Virginia Sedeño-Monge, Margarita Moreno, María del Consuelo Manjarrez, Guadalupe González-Ochoa, Lourdes Millán-Pérez Peña, Julio Reyes-Leyva

“…Background. Cytokines play important roles in the physiopathology of dengue infection; therefore, the suppressors of cytokine signaling (socs) that control the type and timing of cytokine functions could be involved in the origin of immune alterations in dengue. …”
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WKB ameliorates DSS-induced colitis through inhibiting enteric glial cells activation and altering the intestinal microbiota by Qi Sun, Bai-Rong Li, Dong-Hao Li, Xiao-Ying Wang, Qian-Yi Wang, Zhi-Meng Jiang, Shou-Bin Ning, Tao Sun

“…WKB modulated EGCs activity via TNF-like cytokine 1 A inhibition, resulting in reduced glial fibrillary acidic protein expression. …”
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In vitro studies on the immunomodulatory effects of fulvic acid extract from palm oil empty fruit bunch (OPEFB) by Dimarwanita Firda, Mariya Silmi, Nur Annisa Dewi Fitria, Latisya Silva, Faramitha Yora, Goenadi Didiek Hadjar

“…The research focused on assessing the immunomodulatory effects of FA by analysing its impact on cytokine production. In vitro studies used the MTT assay to determine cytotoxicity and ELISA tests to measure cytokines associated with natural immunity (TNF-alpha and Interferon-gamma) and adaptive immunity (IL-2 and TGF-beta). …”
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Retrovirus Entry by Endocytosis and Cathepsin Proteases by Yoshinao Kubo, Hideki Hayashi, Toshifumi Matsuyama, Hironori Sato, Naoki Yamamoto

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Acute cerebral edema: a lethal neurological complication in a patient with COVID-19 infection. Case report and literature review by M. Puodžiūnaitė, R. Sadeckaitė, A. Čikotienė

“…COVID-19 induces CNS damage through various mechanisms including ACE-2 receptor damage, cytokine storm syndrome, secondary hypoxia, blood-brain barrier disruption, and neuroinflammation. …”
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Fungal Exposure and Low Levels of IL-10 in Patients with Sarcoidosis by Marjeta Terčelj, Sanja Stopinšek, Alojz Ihan, Barbara Salobir, Saša Simčič, Ragnar Rylander

“…Sarcoidosis is an inflammatory disease with increased levels of inflammatory cytokines. Previous studies have shown a relation between the degree of granuloma infiltration and serum cytokine levels, except for interleukin- (IL-) 10. …”
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The Anti-Inflammatory Role of Vitamin E in Prevention of Osteoporosis by A. S. Nazrun, M. Norazlina, M. Norliza, S. Ima Nirwana

“…Anticytokine therapy using cytokine antagonists such as IL-receptor antagonist and TNF-binding protein was able to suppress the activity of the respective cytokines and prevent bone loss. …”
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IL-32: A Novel Pluripotent Inflammatory Interleukin, towards Gastric Inflammation, Gastric Cancer, and Chronic Rhino Sinusitis by Muhammad Babar Khawar, Muddasir Hassan Abbasi, Nadeem Sheikh

“…Interleukin-32 is a novel cytokine whose presence has been confirmed in most of the mammals except rodents. …”
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Identification of Macrophage Genotype and Key Biological Pathways in Circulating Angiogenic Cell Transcriptome by Bert R. Everaert, Steven J. Van Laere, Robrecht Lembrechts, Vicky Y. Hoymans, Jean-Pierre Timmermans, Christiaan J. Vrints

“…The CACiv transcriptome strongly related to tissue macrophages, and more specifically to regulatory M2c macrophages. The cytokine expression profile of CACiv was predominantly immune modulatory and resembled the cytokine expression of tumor-associated macrophages (TAM). …”
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Bevacizumab Demonstrates Prolonged Disease Stabilization in Patients with Heavily Pretreated Metastatic Renal Cell Carcinoma: A Case Series and Review of the Literature by Nicole M. Agostino, Rebecca Gingrich, Joseph J. Drabick

“…We report our experience in 4 patients with metastatic RCC who had failed prior cytokine, TKI, and mTOR inhibitors who were treated with bevacizumab as single agent therapy. …”
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PG102 Upregulates IL-37 through p38, ERK, and Smad3 Pathways in HaCaT Keratinocytes by Hyun-keun Kim, Seonung Lim, Min-Jung Bae, Wonwoo Lee, Sunyoung Kim

“…IL-37 is an immunomodulatory cytokine that suppresses inflammation in various cell types and disease models. …”
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Proinflammatory Mediators of Toxic Shock and Their Correlation to Lethality by Teresa Krakauer, Marilyn J. Buckley, Diana Fisher

“…This study examines the cytokine response and lethality of mice exposed to varying doses of staphylococcal enterotoxin B (SEB) or lipopolysaccharide (LPS) and their combinations. …”
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Correlation between Serum Osteopontin and miR-181a Levels in Allergic Rhinitis Children by Wenlong Liu, Qingxiang Zeng, Renzhong Luo

“…Furthermore, serum levels of OPN were positively correlated with Th2 cytokine and negatively correlated with Th1 cytokine. …”
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Effect of Interleukin and Hepcidin in Anemia of Chronic Diseases by Maha F. Yacoub, Hala Fouad Ferwiz, Fadwa Said

“…Recent studies revealed that interleukin-6 (IL-6), a proinflammatory cytokine, and hepcidin, an antimicrobial hepatic peptide, play a key role in ACD pathogenesis. …”
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Studies on the biological effects of ozone: 8. Effects on the total antioxidant status and on interleukin-8 production by V. Bocci, G. Valacchi, F. Corradeschi, G. Fanetti

“…While there is a clear relationship between the ozone dose and IL-8 levels, we have noticed that high TAS and PTG values inhibit the cytokine production. This is in line with the current idea that hydrogen peroxide, as a byproduct of O3 decomposition, acts as a messenger for the cytokine induction.…”
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A Case of Severe Multisystem Inflammatory Syndrome in Children (MIS-C) Treated with Multiple Biologics by Beenish Zulfiqar, Hira Imran, Kathleen Collins

“…It has been postulated that the COVID-19 virus can initiate an autoinflammatory reaction in the body via multiple pathways of cytokine activation. The virus can cause delayed response after 4–8 weeks of acute infection, which resembles a cytokine storm or MAS (macrophage activation syndrome). …”
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Real-Life Use of Tocilizumab in the Treatment of Severe COVID-19 Pneumonia by Ruth Alex, Shabaz Mohiuddin Gulam, Kiran Kumar

“…Coronavirus disease 2019 (COVID-19) can progress to severe respiratory compromise and lead to mortality due to induction of cytokine storm. Tocilizumab (TCZ) is approved by the FDA for the treatment of cytokine release syndrome (CRS). …”
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Optimized Method to Generate Well-Characterized Macrophages from Induced Pluripotent Stem Cells by Qimin Hai, Peter Bazeley, Juying Han, Gregory Brubaker, Jennifer Powers, Claudia M. Diaz-Montero, Jonathan D. Smith

“…<b>Results</b>: The iPSC-derived macrophages generated through this method exhibit characteristic features and cell marker proteins, as well as classical macrophage activities, including lipoprotein uptake, bacterial phagocytosis, cytokine release, and inflammasome activation. We demonstrate the effects of M1-like and M2-like polarization on cytokine release. …”
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Mast Cell Degranulation Decreases Lipopolysaccharide-Induced Aortic Gene Expression and Systemic Levels of Interleukin-6 In Vivo by Jason M. Springer, Vineesh V. Raveendran, Mingcai Zhang, Ryan Funk, Donald D. Smith, Mehrdad Maz, Kottarappat N. Dileepan

“…LPS+C48/80-treated mice presented with a 3-fold higher aortic expression of suppressor of cytokine signaling (SOCS-1) compared to saline-injected groups. …”
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Selected Aspects in the Pathogenesis of Autoimmune Diseases by György Nagy, Peter C. Huszthy, Even Fossum, Yrjö Konttinen, Britt Nakken, Peter Szodoray

“…Additionally, we depict a cytokine imbalance, which gives rise to a biased T-cell homeostasis. …”
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