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2421
Oral Tolerance: A New Tool for the Treatment of Gastrointestinal Inflammatory Disorders and Liver-Directed Gene Therapy
Published 1999-01-01“…Inflammatory bowel diseases are immune-mediated disorders where an imbalance between proinflammatory (T helper cell type 1) and anti-inflammatory (T helper cell type 2) cytokines are thought to play a role in the pathogenesis. …”
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2422
Natural Modulators of Endosomal Toll-Like Receptor-Mediated Psoriatic Skin Inflammation
Published 2017-01-01“…The currently approved biological drugs adalimumab, etanercept, infliximab, ustekinumab, ixekizumab, and secukizumab are antibodies against effector cytokines that participate in the initiation and development of psoriasis. …”
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2423
Effect of fecal microbiota transplantation on ulcerative colitis model in rats: The gut–brain axis
Published 2025-02-01“…Additionally, it examined the relationship between anxiety-related behaviors and colitis and assessed the pro-inflammatory cytokines in the hippocampus. Results: FMT led to lower disease score index and improved colon tissue pathology findings. …”
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2424
Mesenchymal Stem Cell–Sourced Exosomes as Potentially Novel Remedies for Severe Dry Eye Disease
Published 2025-01-01“…MSC-Exos contain a variety of bioactive proteins (growth factors, immunoregulatory molecules, cytokines, and chemokines) lipids, and microRNAs (miRNAs) which affect viability, proliferation, phenotype, and function of eye-infiltrated immune cells. …”
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2425
The Role of Phospholipase C Signaling in Macrophage-Mediated Inflammatory Response
Published 2018-01-01“…Equipped with a broad range of receptors, such as Toll-like receptor 4 (TLR4), CD14, and Fc gamma receptors (FcγRs), macrophages can efficiently recognize and phagocytize invading pathogens and secrete cytokines by triggering various secondary signaling pathways. …”
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2426
Achyranthes bidentata Polysaccharide along with Anti-IL-5 Antibody Inhibits Allergic Lung Inflammation and Airway Hyperresponsiveness Mice Induced by House Dust Mites
Published 2018-01-01“…Asthma is characterized with infiltration by eosinophils in pulmonary parenchyma, high serum IgE, and cytokines like IL-4, IL-5, and IL-13 secreted by allergen-specific T helper cell-2 (Th2) cells. …”
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2427
Effect of Oral and Vaginal Hormonal Contraceptives on Inflammatory Blood Biomarkers
Published 2015-01-01“…We assessed the effect of hormonal contraceptive use on inflammatory cytokines including CRP, monocyte chemotactic protein-1, soluble tumor necrosis factor (sTNF), interleukin-6 (IL-6), and soluble CD40 ligand. …”
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2428
Recent methods for the diagnosis and differentiation of ameloblastoma: a narrative review
Published 2024-12-01“…Cone-beam computed tomography is the most appropriate radiological technique for the detection of ameloblastoma. 18F-FDG PET/CT showed high diagnostic accuracy in identifying metastatic/recurrent lesions postoperatively. The detection of cytokines and gelatinase in the cyst fluid further aids in the diagnosis. …”
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2429
Clinical features and diagnostic criteria of diseases of esophagogastroduodenal zone in patients with gallstone disease after cholecystectomy
Published 2010-06-01“…Inflammatory and erosive-ulcerative changes of esophagogastroduodenal mucosa in these patients develop and progress on a background of disbalance of cytokines and metabolites of connective tissue in blood serum, the most severe in terms over 3 years after cholecystectomy. …”
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2430
CRP and TNF-α Induce PAPP-A Expression in Human Peripheral Blood Mononuclear Cells
Published 2012-01-01“…Analyses were conducted by ultrasensitive ELISA, western blotting, and RT-PCR following stimulation with CRP or TNF-α cytokines. Results. PAPP-A mRNA and protein levels after CRP stimulation peaked at 24 hours, whereas peak PAPP-A mRNA and protein levels were achieved after TNF-α stimulation at only 2 and 8 hours, respectively. …”
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2431
Unusual Cutaneous Manifestations in a Patient with a History of Hepatitis B: A Case of Scleromyxedema and Literature Review
Published 2025-01-01“…Chronic antigenic stimulation from circulating cytokines and viral infections, such as HBV, may contribute to disease development. …”
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2432
A Novel Rose Hip Preparation with Enhanced Anti-Inflammatory and Chondroprotective Effects
Published 2014-01-01“…RH-A and RH-B diminished the secretion of chemokines and cytokines in LPS/IFN-γ-activated PBL, including CCL5/RANTES, CXCL10/IP-10, interleukin- (IL-) 6, and IL-12. …”
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2433
Analysis of Risk Factors for Postoperative Lower Extremity Deep Venous Thrombosis and its Treatment and Nursing
Published 2022-01-01“…Coagulation function and inflammatory cytokines before and after nursing intervention were compared between groups. …”
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2434
Sex-Biased Immune Responses to Antibiotics during Anti-PD-L1 Treatment in Mice with Colon Cancer
Published 2022-01-01“…We observed that two narrow-spectrum antibiotics, neomycin and metronidazole, were more effective in alleviating colitis, as evidenced by the remission of loss of the body weight, enlargement of the spleen, shortening of the colon, secretion of proinflammatory cytokines, and histological score of the colon tissue. …”
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2435
Serum Adiponectin Level in Diabetic Patients with and without Helicobacter pylori Infection: Is There Any Difference?
Published 2014-01-01“…HP changes the level of inflammatory markers and cytokines and changes the adipocyte function by altering the adiponectin level. …”
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2436
Anti-Inflammatory and Antimicrobial Effects of Herbal Formulation Called Apo-Taat Using Extended-Spectrum ß-Lactamase-Producing Escherichia coli Isolates
Published 2025-01-01“…However, overuse and misuse of antibiotics has enabled pathogens to adapt, causing global antibiotic resistance and proliferation of extended-spectrum ß-lactamase-producing Escherichia coli (ESBL-E. coli), which causes diarrhea and high levels of inflammatory cytokines. Apo-taat, consisting of equal proportions of Phyllanthus emblica and Caesalpinia sappan, has been used to treat diarrhea and bloody diarrhea. …”
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2437
Elevated Glucose and Interleukin-1β Differentially Affect Retinal Microglial Cell Proliferation
Published 2017-01-01“…Diabetic retinopathy also presents features of a low-grade chronic inflammatory disease, including increased levels of cytokines in the retina, such as interleukin-1 beta (IL-1β). …”
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2438
Preterm Neonates with Respiratory Distress Syndrome: Ventilator-Induced Lung Injury and Oxidative Stress
Published 2018-01-01“…Despite the small sample studied, data showed that there is a relationship between VILI, proinflammatory cytokines, and oxygen-induced lung injury, but a study considering oxidative marker measurements is needed. …”
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2439
Research progress on the therapeutic roles and mechanisms of hydrogen-rich water in periodontitis
Published 2025-01-01“…Additionally, HRW inhibits the expression of inflammatory cytokines, such as interleukins, inhibits the growth and proliferation of bacterial plaque biofilms, and down-regulates glycosyltransferases and glucan-binding proteins to prevent bacterial adhesion and subsequent development of periodontitis. …”
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2440
Respiratory Syncytial Virus Nonstructural Protein 1 Promotes 5-Lipoxygenase via miR-19a-3p
Published 2022-01-01“…These results suggested that the RSV NS1 might play an important role in the pathogenesis of RSV by activating the 5-LO and subsequent inflammatory cytokines through miR-19a-3p.…”
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