Lipopolysaccharide alters CEBPβ signaling and reduces estradiol production in bovine granulosa cells by Mackenzie J. Dickson, I. Martin Sheldon, John J. Bromfield

“…The transcription factor CCAAT enhancer binding protein beta (CEBPβ) not only facilitates the transcription of LPS regulated cytokines, but also binds to the promoter region of CYP19A1 in humans, mice, and buffalo. …”
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Mechanisms of reduced sensitization by extensive hydrolysis of milk protein concentrate: Impact on the immune response of Th1/Th2 and Treg/Th17 cells in mice by Qiang Cui, Jianjun Cheng, Mingruo Guo

“…This indicated an imbalance of Th1/Th2 in the MPC group, which was confirmed by the results of cytokines and transcription factors in the spleen. …”
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Adenosine A2A Receptors Modulate Acute Injury and Neuroinflammation in Brain Ischemia by Felicita Pedata, Anna Maria Pugliese, Elisabetta Coppi, Ilaria Dettori, Giovanna Maraula, Lucrezia Cellai, Alessia Melani

“…After ischemia the early massive increase of extracellular glutamate is followed by activation of resident immune cells, that is, microglia, and production or activation of inflammation mediators. Proinflammatory cytokines, which upregulate cell adhesion molecules, exert an important role in promoting recruitment of leukocytes that in turn promote expansion of the inflammatory response in ischemic tissue. …”
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Toll-Like Receptor 9 Promotes Cardiac Inflammation and Heart Failure during Polymicrobial Sepsis by Ralph Lohner, Markus Schwederski, Carolin Narath, Johanna Klein, Georg D. Duerr, Alexandra Torno, Pascal Knuefermann, Andreas Hoeft, Georg Baumgarten, Rainer Meyer, Olaf Boehm

“…CASP led to continuous release of bacteria into the peritoneal cavity, an increase of cytokines, and differential regulation of receptors of innate immunity in the heart. …”
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The Beneficial Effect of Human Amnion Mesenchymal Cells in Inhibition of Inflammation and Induction of Neuronal Repair in EAE Mice by Jun Shu, Xiaojuan He, Hong Li, Xue Liu, Xuemei Qiu, Tongliang Zhou, Ping Wang, Xiaojie Huang

“…The production of proinflammatory cytokines such as IFN-γ, TNF-α, IL-1β, and IL-17A in the spleen and CNS was dramatically inhibited. …”
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Elevated Admission Base Deficit Is Associated with a Complex Dynamic Network of Systemic Inflammation Which Drives Clinical Trajectories in Blunt Trauma Patients by Othman Abdul-Malak, Yoram Vodovotz, Akram Zaaqoq, Jesse Guardado, Khalid Almahmoud, Jinling Yin, Brian Zuckerbraun, Andrew B. Peitzman, Jason Sperry, Timothy R. Billiar, Rami A. Namas

“…Three samples within the first 24 h were obtained from all patients and then daily up to day 7 after injury. Twenty-two cytokines and chemokines were assayed using Luminex™ and were analyzed using two-way ANOVA and dynamic network analysis (DyNA). …”
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Comparison of characteristics and immune responses between paired human nasal and bronchial epithelial organoids by Lu Zhu, Wenhao Yang, Jiaxin Luo, Danli Lu, Yanan Hu, Rui Zhang, Yan Li, Li Qiu, Zelian Chen, Lina Chen, Hanmin Liu

“…RSV infection revealed more productive replication in NO, with a downregulated immune pathway identified by RNA sequencing analysis and upregulated levels of pro-inflammatory cytokines in culture supernatants in NO compared to BO. …”
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Helminth Products Potently Modulate Experimental Autoimmune Encephalomyelitis by Downregulating Neuroinflammation and Promoting a Suppressive Microenvironment by Alberto N. Peón, Yadira Ledesma-Soto, Jonadab E. Olguín, Marcel Bautista-Donis, Edda Sciutto, Luis I. Terrazas

“…Importantly, the TcES treatment was able to induce a range of Th2-type cytokines, while suppressing Th1 and Th17 responses. …”
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Specific Antibody Production by Blood B Cells is Retained in Late Stage Drug-naïve HIV-infected Africans by Lydie Béniguel, Evelyne Bégaud, Fabrice Cognasse, Philippe Gabrié, Christophe D. Mbolidi, Mary A. Marovich, Céline Cazorla, Frédéric Lucht, Christian Genin, Olivier Garraud

“…The in vitro antibody production by drug-naïve individuals' PBMCs depended on exogenous cytokines (IL-2 and IL-10) but neither on the re-stimulation of reactive cells in cultures by purified HIV-1-gp 160 antigen nor on the re-engagement of CD40 surface molecules. …”
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Lipoxin Inhibits Fungal Uptake by Macrophages and Reduces the Severity of Acute Pulmonary Infection Caused by Paracoccidioides brasiliensis by Laura R. R. Ribeiro, Flávio V. Loures, Eliseu F. de Araújo, Cláudia Feriotti, Tânia A. Costa, Carlos Henrique Serezani, Sonia Jancar, Vera L. G. Calich

“…In susceptible mice, MLT treatment led to reduced influx of PMN leukocytes, increased recruitment of monocytes, predominant synthesis of anti-inflammatory cytokines, and augmented expression of 5- and 15-lipoxygenase mRNA, suggesting a prevalent LXA4 activity. …”
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A red pomegranate fruit extract-based formula ameliorates anxiety/depression-like behaviors via enhancing serotonin (5-HT) synthesis in C57BL/6 male mice by Xiping Zhu, Dongxiao Sun-Waterhouse, Chun Cui

“…The RPFE formula exhibited the abilities to normalize the levels of serum inflammatory cytokines (NF-κB, TNF-α, IL-6, IL-1β and IFN-γ) and malondialdehyde (MDA), and activities of superoxide dismutase (SOD), catalase (CAT) and nitric oxide synthase (NOS), as well as relieve the injury of hippocampal neurons. …”
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Inhibitory Effect on Cerebral Inflammatory Response following Traumatic Brain Injury in Rats: A Potential Neuroprotective Mechanism of N-Acetylcysteine by Gang Chen, Jixin Shi, Zhigang Hu, Chunhua Hang

“…As a result, we found that NF-κB, proinflammatory cytokines, and ICAM-1 were increased in all injured animals. …”
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Proteomic Profiling of Ex Vivo Expanded CD34-Positive Haematopoetic Cells Derived from Umbilical Cord Blood by Heiner Falkenberg, Teja Falk Radke, Gesine Kögler, Kai Stühler

“…Ex vivo expansion of haematopoetic cells by application of specific cytokines is one approach to overcome boundaries in cord blood transplantation due to limited numbers of haematopoetic stem cells. …”
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Chronic Inflammation and Neutrophil Activation as Possible Causes of Joint Diseases in Ballet Dancers by Leandro da Silva Borges, José Ricardo Bortolon, Vinicius Coneglian Santos, Nivaldo Ribeiro de Moura, Alexandre Dermargos, Maria Fernanda Cury-Boaventura, Renata Gorjão, Tania Cristina Pithon-Curi, Elaine Hatanaka

“…Herein, we investigated the effects of a ballet class on the kinetic profiles of creatine kinase (CK) and lactate dehydrogenase (LDH) activities, cytokines, complement component 3 (C3), and the concentrations of immunoglobulin (Ig), IgA and IgM, in ballerinas. …”
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The Macrophage Inflammatory Proteins MIP1α (CCL3) and MIP2α (CXCL2) in Implant-Associated Osteomyelitis: Linking Inflammation to Bone Degradation by Ulrike Dapunt, Susanne Maurer, Thomas Giese, Matthias Martin Gaida, Gertrud Maria Hänsch

“…In addition to their well described chemokine activity, these cytokines can induce generation of bone resorbing osteoclasts, thus providing a link between bacterial infection and osteolysis.…”
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MCL Plays an Anti-Inflammatory Role in Mycobacterium tuberculosis-Induced Immune Response by Inhibiting NF-κB and NLRP3 Inflammasome Activation by Qingwen Zhang, Xinru Jiang, Weigang He, Kailin Wei, Jinxia Sun, Xiangyang Qin, Yuejuan Zheng, Xin Jiang

“…Evidences showed that MCL decreased the secretion of Mtb-induced inflammatory cytokines (IL-1β and TNF-α) in a dose-dependent manner. …”
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Liver fibrosis and markers of endothelial function at metabolic syndrome and early disorders of carbohydrate metabolism by L. V. Chesnokova, I. M. Petrov, Ye. A. Sidorova, I. A. Troshina, Yu. A. Petrova

“…Presence and severity of liver fibrosis at MS in combination to early disorders of carbohydrate metabolism are related to increase of proinflammatory cytokines, endothelin-1 concentration on a background of reduction of adiponectin contents and decrease of endothelium vasodilation capacity.…”
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Sarcopenia in IBD patients and the role of nutritional and physical activity interventions in its management – a systematic review by Michalina Jurkiewicz, Karolina Siembab, Julia Białeta, Katarzyna Rowińska, Agnieszka Napieralska, Wiktor Garbarczyk, Albert Kapla, Alicja Černohorská, Daria Bednarczyk, Wiktoria Pysiewicz

“…There are multiple mechanisms underlying this complication in IBD: e.g. malnutrition, disrupted gut microbiota, pharmacotherapy, and elevated inflammatory cytokines. Nevertheless, there are some possible interventions that can be undertaken to counteract this complication. …”
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Paradoxical Glucose-Sensitizing yet Proinflammatory Effects of Acute ASP Administration in Mice by Alexandre Fisette, Pegah Poursharifi, Katerina Oikonomopoulou, Mercedes N. Munkonda, Marc Lapointe, Katherine Cianflone

“…ASP supplementation induced a proinflammatory phenotype, with higher levels of cytokines including IL-6 and TNF-α in plasma and in adipose tissue, liver, and skeletal muscle mRNA. …”
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Maresin 1 Mitigates Inflammatory Response and Protects Mice from Sepsis by Ruidong Li, Yaxin Wang, Zhijun Ma, Muyuan Ma, Di Wang, Gengchen Xie, Yuping Yin, Peng Zhang, Kaixiong Tao

“…Our data showed that Mar1 markedly improved survival rate and decreased the levels of proinflammatory cytokines in CLP mice such as interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), and interleukin-1β (IL-1β). …”
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