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Physicochemical properties and cytochromes P-450 kinetics of the trifluoroacetamido derivative of phenacetin
Published 2025-01-01“…The kinetics of cytochromes P-450 (CYP) catalyzed oxidation of phenacetin and TFA-phenacetin were compared using Sprague Dawley (SD) rat liver microsomes. …”
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Target Proteins in Human Autoimmunity: Cytochromes P450 and Udp-Glycoronosyltransferases
Published 2000-01-01“…Cytochromes P450 (CYPs) and UDP-glucuronosyltransferases (UGTs) are targets of autoantibodies in several hepatic and extrahepatic autoimmune diseases. …”
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Effects of Cytochrome P450 Inhibitors on Itraconazole and Fluconazole Induced Cytotoxicity in Hepatocytes
Published 2009-01-01“…The present study was designed to investigate the role of cytochrome P450 inhibitors, SKF 525A, and curcumin pretreatment on the cytotoxicity of antifungal drugs fluconazole and itraconazole. …”
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Screening of flavonoid aglycons’ metabolism mediated by the human liver cytochromes P450
Published 2019-12-01Subjects: Get full text
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Modulatory effects of rutin on the expression of cytochrome P450s and antioxidant enzymes in human hepatoma cells
Published 2016-12-01Subjects: Get full text
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The tyrosine kinase inhibitor lenvatinib is oxidized by rat cytochromes P450 and affects their expression in rat liver
Published 2024-09-01Subjects: Get full text
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Improved 11α-hydroxycanrenone production by modification of cytochrome P450 monooxygenase gene in Aspergillus ochraceus
Published 2021-03-01“…We found that although the cytochrome P450 (CYP) enzyme system in Aspergillus ochraceus strain MF018 could catalyse the conversion of canrenone to 11α-hydroxycanrenone, its biocatalytic efficiency is low. …”
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Novel (Q)SAR models for prediction of reversible and time-dependent inhibition of cytochrome P450 enzymes
Published 2025-02-01Subjects: “…CYP = cytochrome P450…”
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Naturally occurring variation in a cytochrome P450 modifies thiabendazole responses independently of beta-tubulin.
Published 2025-01-01“…Overall, we confirmed that variation in this cytochrome P450 gene is the first locus independent of beta-tubulin to play a role in BZ resistance.…”
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Cytochrome P450 Metabolism of Betel Quid-Derived Compounds: Implications for the Development of Prevention Strategies for Oral and Pharyngeal Cancers
Published 2013-01-01“…Oral and pharyngeal cancers result from interactions between genes and environmental factors (BQ exposure). Cytochrome p450 (CYP) families are implicated in the metabolic activation of BQ- and areca nut-specific nitrosamines. …”
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Continuous Consumption of Reused Palm Oil Induced Hepatic Injury, Depletion of Glutathione Stores, and Modulation of Cytochrome P450 Profiles in Mice
Published 2019-01-01Subjects: “…cytochrome p450…”
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Pharmacokinetic evaluation of the interaction between oral kaempferol and ethanol in rats
Published 2016-12-01Subjects: Get full text
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Cytochrome P450 monooxygenase-mediated eicosanoid pathway: A potential mechanistic linkage between dietary fatty acid consumption and colon cancer risk
Published 2019-12-01“…Keywords: Linoleic acid, Polyunsaturated fatty acids, ω-3 Fatty acids, Colon cancer, Colonic inflammation, Cytochrome P450, Eicosanoids…”
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Effects of proton pump inhibitor (PPI) use on migraine – a critical review
Published 2025-01-01Subjects: Get full text
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Analysis of CYP701A1 genes in gossypium species and functional characterization through gene silencing
Published 2025-02-01Subjects: Get full text
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RETRACTED ARTICLE: Association between cytochrome P450 1A1 (CYP1A1) gene polymorphisms and the risk of renal cell carcinoma: a meta-analysis
Published 2015-01-01“…Abstract Cytochrome P450 1A1 (CYP1A1) usually metabolizes carcinogens to their inactive derivatives but occasionally converts the chemicals to more potent carcinogens. …”
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