Prominent Naturally Derived Oxidative-Stress-Targeting Drugs and Their Applications in Cancer Treatment by Eunsun Lee, Dongki Yang, Jeong Hee Hong

“…In this review, we highlighted the anti-cancer components (plumbagin, quercetin, resveratrol, curcumin, xanthatin, carvacrol, telmisartan, and sulforaphane) that modulate ROS levels and the recent targeting platforms used to increase the application of anti-cancer drugs and the developed delivery platforms with diverse mechanisms of action. …”
Get full text

ALLERGIC RHINITICAL THERAPY WITH ACUPUNCTURE, LEGUNDI AND TEMULAWAK HERBS by Maya Septriana, Novita Purnamasari, Herra Studiawan

“…Results: The active compounds viteosin-A, viteksikarpin, and vitetrifolin-E which can inhibit releasing  histamine and curcumin as anti-inflammatory have an effect on sneezing in allergic rhinitis. …”
Get full text

Elucidating Molecular Interactions of Natural Inhibitors with HPV-16 E6 Oncoprotein through Docking Analysis by Satish Kumar, Lingaraja Jena, Sneha Galande, Sangeeta Daf, Kanchan Mohod, Ashok K. Varma

“…In the recent years, different compounds from natural origins, such as carrageenan, curcumin, epigallocatechin gallate, indole-3-carbinol, jaceosidin, and withaferin, have been used as a hopeful source of anticancer therapy. …”
Get full text

Harnessing the immunomodulatory potential of natural products in precision medicine—a comprehensive review by Maya G. Pillai, Helen Antony

“…Clinical applications of NP-based immunotherapies, such as curcumin and resveratrol in cancer treatment, highlight their diverse pharmacological properties. …”
Get full text

Docking to Explicate Interface between Plant-Originated Inhibitors and E6 Oncogenic Protein of Highly Threatening Human Papillomavirus 18 by Satish Kumar, Lingaraja Jena, Maheswata Sahoo, Mrunmayi Kakde, Sangeeta Daf, Ashok K. Varma

“…Traditionally, different natural compounds such as withaferin A, artemisinin, ursolic acid, ferulic acid, (-)-epigallocatechin-3-gallate, berberin, resveratrol, jaceosidin, curcumin, gingerol, indol-3-carbinol, and silymarin have been used as hopeful source of cancer treatment. …”
Get full text

The Effects of Polyphenols on Texture and Flavor of Egg Yolk: A Molecular Docking Study by Tingting Tang, Ruyi Zhang, Cuihua Chang, Junhua Li, Luping Gu, Yanjun Yang, Yujie Su

“…Tea polyphenols (TP), rosmarinic acid (RE), and curcumin (CC) showed significant antioxidant properties during egg yolk processing and could effectively reduce lipid oxidation products (decreased by 68.9%, 76.4%, and 58.61%, respectively) and protein oxidation products (decreased by 47.49%, 37.47%, and 52.51%, respectively) and volatile odor components (styrene, nonanal and 1-octene-3-ol). …”
Get full text

THE EFFECT OF ABDOMINAL MASSAGE AND KUNYIT ASAM HERBS TO REDUCE PRIMARY MENSTRUAL PAIN (DYSMENORRHEA) by Dwi Setiani Sumardiko, Alyaa’ Maulida Rizki Roswandi, Neny Purwitasari, Rini Hamsidi

“…Result: Turmeric and tamarind contain active compounds curcumin and anthocyanin which work together to inhibit cyclooxygenase (COX) reactions so that they can inhibit or reduce inflammation and uterine contractions which cause menstrual pain. …”
Get full text

Pengaruh Kombinasi Metformin dan Ekstrak Kunyit terhadap Kadar High Density Lipoprotein, Interleukin-6 dan Tumor Necrosis Factor-a by Fathia Kesuma Dinanti, Sri Priyantini Mulyani, Chodidjah - -

“…Turmeric is one of the natural ingredients with antioxidant, anti-cholesterol, and anti-inflammatory properties through its active substance, curcumin. Objective: To prove the effectiveness of the combination of metformin and turmeric extract on HDL levels, TNFa levels, and IL-6 levels in Streptozotocin-Nicotinamide-induced Wistar rats. …”
Get full text

A Comprehensive Review on Bio-Based Polybenzoxazines Emphasizing Their Antimicrobial Property by Shakila Parveen Asrafali, Thirukumaran Periyasamy, Jaewoong Lee

“…Notable bio-based benzoxazines include derivatives synthesized from renewable resources like curcumin, vanillin, and eugenol, which exhibit substantial antimicrobial activity and environmental friendliness. …”
Get full text

Nature-derived microneedles with metal-polyphenolic networks encapsulation for chronic soft tissue defects repair: Responding and remodeling the regenerative microenvironment by Chengyang Zhu, Zun Fan, Zhijie Cheng, Jun Yin, Lei Qin, Xin Zhao

“…To enhance the intrinsic bioactivities, metal-polyphenolic networks (MPNs) coordinated from copper (Cu) and curcumin (Cur) are designed and encapsulated into NMs. …”
Get full text

Elucidation of the Inhibitory Effect of Phytochemicals with Kir6.2 Wild-Type and Mutant Models Associated in Type-1 Diabetes through Molecular Docking Approach by Manaswini Jagadeb, V Badireenath Konkimalla, Surya Narayan Rath, Rohit Pritam Das

“…The current work is intended to investigate the affinity of four phytochemicals namely, curcumin (Curcuma longa), genistein (Genista tinctoria), piperine (Piper nigrum), and pterostilbene (Vitis vinifera) in a normal as well as in a mutant kir6.2 model by adopting a molecular docking methodology. …”
Get full text

On Ve-Degree and Ev-Degree Topological Properties of Hyaluronic Acid‐Anticancer Drug Conjugates with QSPR by Syed Ajaz K. Kirmani, Parvez Ali, Faizul Azam, Parvez Ahmad Alvi

“…In this article, we propose the general ve-inverse sum indeg index ISIα,βveG and general ve-Zagreb index MαveG of graph G and compute ISIα,βveG,MαveG, and MαevG (general ev-degree index) of hyaluronic acid-curcumin/paclitaxel conjugates, renowned for its potential anti-inflammatory, antioxidant, and anticancer properties, by using molecular structure analysis and edge partitioning technique. …”
Get full text

Formulation of Cefdinir Ternary Solid Dispersion and Stability Study under Harsh Conditions by Naamaa A. Naama, Ghaidaa S. Hameed, Dalya Basil Hanna, Zainab H. Mahdi

“…The ternary SD is prepared by the solvent evaporation method using CEF, curcumin, and polyvinylpyrrolidone k30 in a weight ratio of 1:1:1. …”
Get full text

Underlying Anticancer Mechanisms and Synergistic Combinations of Phytochemicals with Cancer Chemotherapeutics: Potential Benefits and Risks by Muhammad Ayaz, Asif Nawaz, Sajjad Ahmad, Osama F. Mosa, Alashary Adam Eisa Hamdoon, Modawy Alnour Khalifa, Abdul Sadiq, Farhat Ullah, Abdul Wadood, Atul Kabra, H. C. Ananda Murthy

“…Several lead phytochemicals including curcumin, resveratrol, quercetin, and cannabinoids synergistically act with cancer chemotherapeutics reducing cell proliferation and inducing apoptosis and cell cycle arrest. …”
Get full text

Evaluating Dose- and Time-Dependent Effects of Vitamin C Treatment on a Parkinson’s Disease Fly Model by Huynh Man Anh, Dao My Linh, Vuu My Dung, Dang Thi Phuong Thao

“…Previous studies demonstrated that curcumin at 1 mM and vitamin C at 0.5 mM could improve PD-like phenotypes induced by this knockdown. …”
Get full text

Effect of nanocurcumin (Curcuma longa) on lung histopathology in rats exposed to carbon black by El Roy Achmad Rahmaniabdi, Imam Mustofa, Eka Pramyrtha Hestianah, Widjiati Widjiati, Rochmah Kurnijasanti, Hani Plumeriastuti

“… Background Exposure to carbon black can induce respiratory toxicity, leading to tissue remodeling, inflammation, and fibrosis. Curcumin, a compound from Curcuma longa, has been shown to exert protective effects on lung tissue by inhibiting cell proliferation and reducing alveolar epithelial thickening and inflammatory responses. …”
Get full text

The impact of particle size of nanostructured lipid carriers on follicular drug delivery: A comprehensive analysis of mouse and human hair follicle penetration by Saman Heydari, Mohammad Barzegar-Jalali, Mostafa Heydari, Afsaneh Radmehr, Ana Cláudia Paiva-Santos, Maryam Kouhsoltani, Hamed Hamishehkar

“…Also, it is essential to investigate the reliability of the results between human studies and mouse models. Methods: Curcumin-loaded nanostructured lipid carriers (NLCs), as a fluorescent agent, with three different particle size ranges were prepared using the hot homogenization method and applied topically on the mouse and human study groups. …”
Get full text

The feasibility study of natural pigments as food colorants and seasonings pigments safety on dried tofu coloring by Wei-Sheng Lin, Pei Hua He, Chi-Fai Chau, Bo-Kang Liou, Shiming Li, Min-Hsiung Pan

“…Overall, Gardenia Yellow, Curcumin, and Radish Red could overcome the application restrictions in multiple-phase food coloring system and simultaneously soy sauce as a coloring agent was safety. …”
Get full text

Exploring nanocomposite materials in clinical dermatology: Innovations for treating skin diseases by Sandipan Dasgupta, Subhasundar Maji, Sanjay Dey, Moitreyee Chattopadhyay, Ananya Chanda, Satarupa Acharjee, Kousik Santra, Kazi Asraf Ali

“…For example, graphene oxide-based nanocomposites improve penetration of the skin’s stratum corneum, facilitating deeper drug delivery. Silver and curcumin-based nanocomposites provide controlled release of active ingredients over extended periods, protecting bioactive compounds from degradation. …”
Get full text

Targeted inhibition of ferroptosis in bone marrow mesenchymal stem cells by engineered exosomes alleviates bone loss in smoking-related osteoporosis by Yao Wang, Lin Sun, Zhenglin Dong, Tianyu Zhang, Leining Wang, Yihui Cao, Hui Xu, Chenglei Liu, Bo Chen

“…F6-(DSS)6-exo enabled the targeted delivery of curcumin, restoring the osteogenic differentiation potential of BMSCs and mitigating bone loss in SROP mouse models. …”
Get full text