Enolase inhibitors as therapeutic leads for Naegleria fowleri infection. by Jillian E Milanes, Victoria C Yan, Cong-Dat Pham, Florian Muller, Samuel Kwain, Kerrick C Rees, Brian N Dominy, Daniel C Whitehead, Steven W Millward, Madison Bolejack, Roger Shek, Logan Tillery, Isabelle Q Phan, Bart Staker, E Ashley Moseman, Xiang Zhang, Xipeng Ma, Audriy Jebet, Xinmin Yin, James C Morris

“…However, intranasal HEX delivery was not curative as brains of six of the eight survivors were positive for amoebae. …”
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Advanced colon cancer detection: Integrating context-aware multi-image fusion (Camif) in a multi-stage framework by M.V.R. Vittal

“…In this work we used publicly available Curated Colon Dataset to diagnose conditions such as esophagitis, ulcerative colitis, polyps, and normal cases. …”
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Mining hypertension predictors using decision tree: Baseline data of Kharameh cohort study by abbas Rezaianzadeh, Samane Nematolahi, maryam jalali, Shayan Rezaeianzadeh, Masoumeh Ghoddusi Johari, Seyed Vahid Hosseini

“…This model can be useful for early screening and improving preventive and curative health services in health promotion. …”
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Phytochemical and Antimicrobial Study for Phoenix dactylifera L. (Ajwa Date) Seeds Extract by Zainab Y.M. Hasan, Ghydaa H. Aljeboury, Wael A. Obaid, Rawaa A. Khalaf

“…Conclusions: Ajwa date seeds represent good sources rich in many secondary metabolite components, making the plant a candidate model curative agent for bacterial resistance species that are considered an aggravating problem in society at the present time.       …”
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Eosinophilic Asthma Secondary to Adjuvant Anti-PD-1 Immune Checkpoint Inhibitor Treatment in a Melanoma Patient by P. Kissoonsingh, B. Sutton, Syed U. Iqbal, Lalit Pallan, Neil Steven, L. Khoja

“…Although a safe rechallenge with pembrolizumab was possible, treatment in the adjuvant setting is curative in intent and long-term safety follow-up is required to assess for delayed toxicity and long-term health implications. …”
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Cholangiocarcinoma combined with biliary obstruction: an exosomal circRNA signature for diagnosis and early recurrence monitoring by Ningyuan Wen, Dingzhong Peng, Xianze Xiong, Geng Liu, Guilin Nie, Yaoqun Wang, Jianrong Xu, Shaofeng Wang, Sishu Yang, Yuan Tian, Bei Li, Jiong Lu, Nansheng Cheng

“…A prognostic model of CCA undergoing curative-intent surgery was established by calculating early recurrence score, verified with bile samples (Bile-ERS, C-index=0.783) and serum samples (Serum-ERS, C-index = 0.782). …”
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Evaluation of treatment strategies for patients with stage IIIA non-small cell lung cancer in the immunotherapy era by Amy Alabaster, Jeffrey B. Velotta, Haley I. Tupper, Mark S. Walker, Yanina Natanzon

“…Data was from ConcertAI's curated EHR Patient360™ NSCLC real-world care product. …”
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Re-defining pT4b buccal mucosa squamous cell carcinoma: Looking beyond palliation in select patients by Prateek V. Jain, Kapila Manikantan, Gary M. Clark, Indranil Mallick, Sanjoy Chatterjee, Indu Arun, Paromita Roy, Lateef Zameer, Pattatheyil Arun

“…Material and methods: The cohort for this retrospective study comprised 213 patients with pT4a/b BMSCC, treated with curative intent surgery from August 2011 through December 2019. …”
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Spatial identification of regions exposed to multi-hazards at the pan-European level by T.-E. Antofie, T.-E. Antofie, S. Luoni, A. Tilloy, A. Sibilia, S. Salari, G. Eklund, D. Rodomonti, C. Bountzouklis, C. Corbane

“…<p>The European Commission Disaster Risk Management Knowledge Centre (DRMKC) has developed and hosts a web platform, the Risk Data Hub (RDH), designed to facilitate access to and sharing of curated, EU-wide risk data, tools, and methodologies, ultimately supporting disaster risk management (DRM) initiatives. …”
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Clinical Significance of Perioperative Minimal Residual Disease Detected by Circulating Tumor DNA in Patients With Lung Cancer With a Long Follow-up Data: An Exploratory Study by Shuta Ohara, MD, PhD, Kenichi Suda, MD, PhD, Sumedha Sudhaman, PhD, Akira Hamada, MD, PhD, Masato Chiba, MD, PhD, Masaki Shimoji, MD, PhD, Toshiki Takemoto, MD, PhD, Ekaterina Kalashnikova, PhD, Samantha K. Cheung, PhD, Michael Krainock, MD, PhD, Jordan Feeney, BS, Himanshu Sethi, MPH, Minetta C. Liu, MD, Junichi Soh, MD, PhD, Yasuhiro Tsutani, MD, PhD, Tetsuya Mitsudomi, MD, PhD

“…Introduction: Molecular residual disease detected by circulating tumor DNA (ctDNA) has been reported to be predictive of patients’ outcomes in various types of cancers after curative intent treatment. Nevertheless, additional detailed information regarding the association of longitudinal ctDNA detection with long-term follow-up in lung cancer is needed. …”
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Impact of postoperative morbidity on the prognosis of patients with hepatocellular carcinoma after laparoscopic liver resection: a multicenter observational study by Shiye Yang, Haishun Ni, Aixian Zhang, Jixiang Zhang, Hong Zang, Zhibing Ming

“…Hepatocellular carcinoma patients who underwent curative-intent laparoscopic liver resection were included. …”
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Comparison of autologous hematopoietic cell transplantation, matched sibling donor hematopoietic cell transplantation, and chemotherapy in patients with favorable- and intermediate... by Mingyang Wang, Shulian Chen, Qiuqiu Zhang, Linyu Yuan, Xue Wang, Junshi Zhang, Xiaoyu Zhang, Yigeng Cao, Dongmei Li, Xinxiao Lu, Meijiao Wang, Xiaosi Jiang, Rongli Zhang, Xin Chen, Qiaoling Ma, Jialin Wei, Donglin Yang, Yi He, Aiming Pang, Sizhou Feng, Mingzhe Han, Weihua Zhai, Xingli Zhao, Erlie Jiang

“…IntroductionHematopoietic stem cell transplantation (HSCT) and chemotherapy are considered potentially curative options for post-remission therapy in acute myeloid leukemia (AML). …”
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Pancreatic resection with perioperative drug repurposing of propranolol and etodolac: trial protocol of the phase-II randomised placebo controlled PROSPER trial by Phillip Knebel, Thilo Hackert, Markus W Büchler, Ilse Rooman, Markus K Diener, Felix J Hüttner, André L Mihaljevic, Oliver Strobel, Gauthier Bouche, Johannes Hüsing

“…Despite advances in systemic chemotherapy, the mainstay of curative therapy for non-metastatic disease is surgical resection. …”
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Real world study on combining local interventions with systemic therapy in unresectable hepatocellular carcinoma by Zhaosong Xue, Ming Yao, Kang Chen, Taiyun Huang, Jianjun Li, Jian Chen, Fei Huang, Yubin Huang, Xiaoyong Cai, Yihe Yan

“…Notably, patients without extrahepatic disease and those who exhibited a radiographic response to triple therapy were more likely to be eligible for curative resection. Importantly, hepatectomy independently associated with a favorable overall survival (HR, 0.388; 95% CI, 0.177–0.847; P = 0.017). …”
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E_N_T_R_O_P_Y: Monocentric analysis of rectal cancer radio-chemotherapy treatment in patients of young age by E. Meldolesi, A. Nicolì, N. Dinapoli, G. Chiloiro, A. Romano, R. Menghi, R. Persiani, F. Pacelli, C. Coco, C. Ratto, S. Manfrida, L. Boldrini, B. Corvari, M.A. Gambacorta

“…We decided to examine patients with rectal cancer treated in our centre in the last 15 years with curative neoadjuvant radiochemotherapy comparing outcomes in the two groups under and over 55 years old. …”
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A Survey of Camouflaged Object Detection and Beyond by Fengyang Xiao, Sujie Hu, Yuqi Shen, Chengyu Fang, Jinfa Huang, Longxiang Tang, Ziyun Yang, Xiu Li, Chunming He

“…For those interested, a curated list of COD-related techniques, datasets, and additional resources can be found at https://github.com/ChunmingHe/awesome-concealed-object-segmentation.…”
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Exploring the anti-inflammatory effects of phytochemicals in attenuating interstitial cystitis-a literature review by Irfan Anjum, Ayesha Nasir, Faiza Naseer, Faiza Naseer, Ahsan Ibrahim, Bisma Rehman, Fawad Bashir, Qura Tul Ain

“…The current medicinal and pharmacological research focuses on the protective and curative effects of phytochemicals in several ailments. …”
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Intraperitoneal paclitaxel for patients with primary malignant peritoneal mesothelioma: a phase I/II dose escalation and safety study—INTERACT MESO by Job P van Kooten, Jacobus W A Burger, Cornelis Verhoef, Joachim G J V Aerts, Eva V E Madsen, Alexandra R M Brandt-Kerkhof, Stijn L W Koolen, Ron H J Mathijssen, Michelle V Dietz, Niels A D Guchelaar

“…The only potentially curative treatment is cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC). …”
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Genomic characterization of Achromobacter genogroup 20 and identification of a potential species-specific marker by Mariana Papalia, Rocio Stucchi, Valeria Alexander, Liliana Clara, Mariángeles Visus, Gabriel Gutkind, Marcela Radice

“…Coding sequences were predicted and confirmed with RAST and BLAST, and resistance determinants were evaluated using Resfinder and manual curation. All Achromobacter spp. genomes were obtained from NCBI, and the presence of blaOXA was investigated. …”
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Essential core competencies for scope of practice of paediatric oncology nurses in Latin America: a scoping review protocol by Luís Carlos Lopes-Júnior, Regina Aparecida Garcia Lima, Soad Fuentes-Alabi, Edmara Bazoni Soares Maia, Karina de Cássia Braga Ribeiro, Courtney E Sullivan, Monnie Abraham, Lorena Segovia Weber, Liliana Vásquez Ponce

“…Introduction Nurses comprise the largest group of health workers globally and are essential to the provision of care necessary for delivering curative therapy to children with cancer. In high-income countries, previous studies of the nurse workforce have shown an association between patient morbidity and mortality and nursing-related factors such as staffing, education and the nursing practice environment. …”
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