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15421
Targeted ErbB4 receptor activation prevents D-galactose-induced neuronal senescence via inhibiting ferroptosis pathway
Published 2025-01-01“…Additionally, mouse hippocampal HT22 neuronal cell cultures were utilized to corroborate the in vivo findings.ResultsThe targeted activation of ErbB4 receptor by E4A significantly ameliorated the behavioral deficits induced by D-gal in mice, demonstrating an effect comparable to that of melatonin, a natural inhibitor of in vivo senescence and ferroptosis. …”
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15422
Exendin-4 Exacerbates Burn-Induced Morbidity in Mice by Activation of the Sympathetic Nervous System
Published 2019-01-01“…Exendin-4 on T cell function in vitro was examined in cultured splenocytes in the presence of β-adrenoceptor antagonist propranolol (1 nmol/L) or GLP-1R antagonist exendin (9-39) (1 μmol/L), whereas its in vivo effect was determined by i.p. injection of exendin-4 (2.4 nmol/kg) in mice. …”
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15423
A phenomenological study of knowledge concealment in country water and sewage engineering company
Published 2024-08-01“…In addition, organizational culture, senior management support and organizational communication also affect knowledge disclosure behavior. …”
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15424
IGJR issue 1/2018
Published 2017-06-01“…For instance, does high pro-elderly policy bias in both Southern and Central-and-Eastern Europe (Vanhuysse 2014) actually mask different generational or governance cultures? How do these cultures contrast with those of elderly but more age group-balanced societies such as in Nordic Europe? …”
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15425
L’amphithéâtre de Reims/Durocortorum : nouveaux éléments de localisation et de datation
Published 2022-11-01“…Though knowledge about the amphitheater itself remains very limited, the location of and date of foundation for this emblematic monument of Roman culture in Reims now appear to have been identified thanks to this excavation.…”
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15426
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15427
Beliefs in Good and Bad Days among the Tatars in Dobrudja and Among the Polish-Lithuanian Tatars (Preliminary Remarks)
Published 2023-10-01“…By means of their comparative analysis, the manifestations of the so-called folk (popular) Islam, the connection with the common Turkic and all-Islamic heritage are revealed, the role of the contexts of the Balkan and Baltic cultures is outlined. It is assumed that what has been preserved from the beliefs of the Tatars in Dobrudja and the Polish-Lithuanian Tatars reflects the relationship between the spoken and written word: for the Tatars in Dobrudja it is rather an oral, everyday version, while the Polish-Lithuanian Tatars have a written primary source. …”
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15428
Investigation of the Mechanism Underlying Calcium Dobesilate-Mediated Improvement of Endothelial Dysfunction and Inflammation Caused by High Glucose
Published 2019-01-01“…Human umbilical vein endothelial cells (HUVECs) were cultured with different D-glucose concentrations to determine the effects of high glucose on HUVEC gene expression. …”
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15429
The In Vitro Immunomodulatory Effects of Gold Nanocomplex on THP-1-Derived Macrophages
Published 2022-01-01“…While at protein level, cells were treated with our nanocomplex: IL-1β, IL-6, TNF-α, and IL-12p70 and were significantly decreased (p<0.00005,p<0.005,p<0.05,p<0.00005), and IL-10 was found to be significantly increased in culture compared to the untreated control group (p<0.005). …”
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15430
INNOVATIVE METHODS OF TEACHING HISTORY AT MODERN UNIVERSITIES
Published 2017-12-01“…History plays an important role in the course of formation of a citizen and development of critical thinking of a personality as an element of a common culture. However, new federal standards require a drastic reduction of the classroom hours for studying a History course by students of non-humanitarian specialties, and, at the same time, enhancement of the contents of a discipline (its reorientation from History of Russia towards World History). …”
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15431
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15432
L’échelon manquant ? Les archives municipales en Algérie : histoire de fonds et possibilités historiographiques
Published 2024-12-01“…The challenge is not just to explore these collections; it is also to understand how they are preserved, destroyed and filed, so as to better define their historiographical interest.A brief history of archival culture in Algeria, from 1830 to the present day, is the first stage in these reflections. …”
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15433
Biofloc technology on the intensive aquaculture of bronze corydoras ornamental fish Corydoras aeneus with different stocking densities
Published 2019-06-01“…The water quality during the rearing period, such as temperature, pH, alkalinity, ammonia, nitrite, and nitrate, were in a tolerable range for corydoras culture. The total suspended solids tended to be higher due to higher stocking density. …”
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15434
Targeted protein degradation through site-specific antibody conjugation with mannose 6-phosphate glycan
Published 2024-12-01“…The M6P-conjugated antibody against a protein of interest (POI) efficiently internalized targeted soluble proteins, such as human tumor necrosis factor (TNF), in both cancer cell lines and human immune cells, through the endo-lysosomal pathway as demonstrated by confocal microscopy and flow cytometry. TNF in cell culture media was significantly depleted after the cells were incubated with the M6P-conjugated antibody. …”
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15435
Carbapenem-resistant Enterobacterales (CRE) colonisation as a predictor for subsequent CRE infection: A retrospective surveillance study
Published 2025-01-01“…Of patients colonised with a CRE, 21.2% subsequently developed a culture-positive infection within 180 days from the initial colonisation result and the majority within 30 days. …”
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15436
Alloplasmic recombinant lines (H. vulgare)-T. aestivum with 1RS.1BL translocation: initial genotypes for production of common wheat varieties
Published 2018-08-01“…This paper presents the results of investigation into a group of recombinant alloplasmic lines (L-17F4), as well as into doubled haploids (DH) lines – alloplasmic DH-17-lines obtained from anther culture of alloplasmic lines (L-17F2). The most productive of these lines were used as initial breeding genotypes. …”
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15437
The Identification of Molecular Ploidy Status of Abnormal Pronuclear Zygotes Reveals a Significant Number of Euploid Blastocysts Available for Conception
Published 2024-12-01“…<b>Methods:</b> Upon successful fertilization, pronuclear numeration was noted, and zygotes were cultured to the blastocyst stage. Biopsied trophectoderm cells were then lysed, and the isolated DNA was whole-genome amplified followed by library preparation. …”
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15438
Effectivity of prebiotic mannan oligosaccharides as the immunity enhancer and growth response on whiteleg shrimp Litopenaeus vannamei against white spot disease
Published 2018-05-01“…A completely randomized design was used in the study. Shrimps were cultured at the stock density of 15 shrimps 40/L for each treatment in triplicates. …”
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15439
Rotifer Brachionus rotundiformis enriched with taurine for survival and growth of larval milkfish Chanos chanos
Published 2025-01-01“…Three days old larvae were given rotifers enriched with taurine at 0, 25, 50, or 75 mg/L. Larvae were cultured until they were 18 days old. The results showed that the taurine content in rotifers was higher in rotifer at 50 mg/L treatment, then decreased at the 75 mg/L treatment. …”
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15440
Internal Facilitation by Health Assistants for the “WHO Lay Health Worker Dementia Care” in Rural Uganda: A Formative Evaluation
Published 2025-02-01“…To address these needs, we gathered key stakeholders’ perspectives on a culturally tailored model employing lay health workers, supported by health assistants as internal facilitators, to implement the World Health Organization dementia toolkit in rural communities.Methods: We conducted a formative qualitative study, utilizing one-on-one interviews with health assistants, district health team members, and primary healthcare providers in rural Uganda. …”
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