Awareness and attitudes of pregnant women concerning genetic disorders and pregnancy termination in northeastern Iran by Nafiseh Todarbary, Abouzar Irandegani, Mojtaba Meshkat, Aida Gholoobi, Tayebeh Hamzehloei

“…Conclusion The findings emphasize the importance of comprehensive genetic counseling, informed decision-making in prenatal care, advocating for policy reviews, and culturally sensitive guidelines in Iran.…”
Get full text

Effects of Stromal Cell-Derived Factor-1α Secreted in Degenerative Intervertebral Disc on Activation and Recruitment of Nucleus Pulposus-Derived Stem Cells by Jinwei Ying, Zhihua Han, Shishen Pei, Linghao Su, Dike Ruan

“…We found SDF-1α was highly expressed and secreted by the native disc cells when cultured in the proinflammatory mediators in vitro mimicking the degenerative settings. …”
Get full text

Acute Pulmonary Aspergillosis as a Severe Complication of Influenza, Pneumococcal Pneumonia, and Staphylococcus aureus Bacteremia in ICU by Tamara Seitz, Wolfgang Hoepler, Stephanie Neuhold, Christoph Wenisch

“…A CT scan showed a resolving inflammatory infiltrate bilateral caverns with markedly thickened walls. A culture from a bronchoalveolar lavage grew Aspergillus fumigatus. …”
Get full text

The Comparison of the Immunologic Properties of Stem Cells Isolated from Human Exfoliated Deciduous Teeth, Dental Pulp, and Dental Follicles by Selin Yildirim, Noushin Zibandeh, Deniz Genc, Elif Merve Ozcan, Kamil Goker, Tunc Akkoc

“…Then, lymphocyte proliferation, the number of CD4+FoxP3+ T regulatory cells, and the levels of Fas/Fas ligand, IL-4, IL-10, and IFN-γ in the culture supernatant were measured. Results. The DFSCs exhibited an enhanced differentiation capacity and an increased number of CD4+FoxP3+ T lymphocytes and suppressed the proliferation and apoptosis of PBMCs compared with SHEDs and DPSCs. …”
Get full text

Role of CXCL10 released from osteocytes in response to TNF-α stimulation on osteoclasts by Mariko Miura, Hideki Kitaura, Fumitoshi Ohori, Kohei Narita, Jiayi Ren, Takahiro Noguchi, Aseel Marahleh, Jinghan Ma, Angyi Lin, Ziqiu Fan, Itaru Mizoguchi

“…Additionally, in the transwell co-culture system, TNF-α induced the migration of osteoclast precursors. …”
Get full text

Cold Plasma Activity Against Biofilm Formation of Prosthetic Joint Infection Pathogens by Christopher Spiegel, Débora C. Coraça-Huber, Michael Nogler, Rohit Arora, David Putzer

“…Methods: Biofilm was formed with <i>Staphylococcus aureus</i> ATCC 29213 and <i>Staphylococcus epidermidis</i> ATCC 12228 cultures on TMZF discs. Plasma treatments using air plasma and argon plasma were conducted on discs containing the established biofilm while the temperature was measured. …”
Get full text

Selected Parameters of Nutritional and Pro-Health Value in the Common Carp (Cyprinus carpio L.) Muscle Tissue by J. Kłobukowski, K. Skibniewska, K. Janowicz, F. Kłobukowski, E. Siemianowska, E. Terech-Majewska, J. Szarek

“…The muscle tissue of fish cultured in farms with a semiextensive technological level was characterised by the highest content of unsaturated fatty acids. …”
Get full text

Pronerve Growth Factor Induces Angiogenesis via Activation of TrkA: Possible Role in Proliferative Diabetic Retinopathy by Sally L. Elshaer, Mohammed A. Abdelsaid, Ahmad Al-Azayzih, Parag Kumar, Suraporn Matragoon, Julian J. Nussbaum, Azza B. El-Remessy

“…The angiogenic response of aqueous humor samples from PDR patients was examined in human retinal endothelial cells in the presence or absence of anti-proNGF antibody. Additional cultures were treated with mutant-proNGF in the presence of specific pharmacological inhibitors of TrkA and p75NTR receptors. …”
Get full text

Extensive Characterization of Mesenchymal Stem Cell Marker Expression on Freshly Isolated and In Vitro Expanded Human Adipose-Derived Stem Cells from Breast Cancer Patients by Premrutai Thitilertdecha, Visnu Lohsiriwat, Poonsin Poungpairoj, Varangkana Tantithavorn, Nattawat Onlamoon

“…Results from this study demonstrated that fat tissue collected from patients contains ADSC with a highly homogenous phenotype. The in vitro culture of these cells maintained their homogeneity with modified CD34 and CD105 expression, suggesting the expansion from a single population of ADSC.…”
Get full text

Differential Proliferative Characteristics of Alveolar Fibroblasts in Interstitial Lung Diseases: Regulative Role of IL-1 and PGE2 by Elizabeth Fireman, Shlomo Ben Efraim, Joel Greif, Hava Peretz, Shmuel Kivity, Marcel Topilsky, Yosef Rodrig, A. Yellin, Ron N. Apte

“…Steady levels of IL-1α and βmRNA were expressed in unstimulated and stimulated cultures. Fb from SA and HP patients could be stimulated by LPS to secrete significantly higher levels of PGE2 than those detected in supernatants from LPS stimulated Fb of DIF patients. …”
Get full text

Occurrence of macrolides resistance in Legionella pneumophila ST188: Results of the Belgian epidemiology and resistome investigation of clinical isolates by Charlotte Michel, Fedoua Echahidi, Geraldine De Muylder, Max Sewell, Ian Boostrom, Olivier Denis, Owen B. Spiller, Denis Pierard

“…Routine typing by cgMLST allows good discrimination and the first clinical isolate reported as resistant for macrolides was cultured, underscoring the need to define resistance breakpoints and incorporate antimicrobial susceptibility testing as routine clinical investigation practice.…”
Get full text

Strains of a virtuoso: pacemaker infection and ventricular tachycardia in a violinist by Yuanguo Chen, Haibo Zhang, Qi Qiao, Lian Ma

“…Despite initial antibiotic treatment, the infection persisted with slightly elevated C-reactive protein (CRP) and negative cultures. The VT originated from the right ventricular outflow tract (RVOT), as confirmed by echocardiography and ECG findings. …”
Get full text

The use of Spirulina platensis as tilapiaOreochromis niloticusdiet supplementation by Nur Bambang Priyo Utomo, Firsty Rahmatia, Mia Setiawati

“…Tilapia rearedin aquarium sized 50×40×35 cm3 filledwith 30 cm waterand provided altrecirculation system. Fish were cultured for 40 days and fed at satiation with three times feeding frequency. …”
Get full text

Chemogenomic Screening in a Patient‐Derived 3D Fatty Liver Disease Model Reveals the CHRM1‐TRPM8 Axis as a Novel Module for Targeted Intervention by Sonia Youhanna, Aurino M. Kemas, Shane C. Wright, Yi Zhong, Britta Klumpp, Kathrin Klein, Aikaterini Motso, Maurice Michel, Nicole Ziegler, Mingmei Shang, Pierre Sabatier, Aimo Kannt, Hongda Sheng, Nuria Oliva‐Vilarnau, Florian A. Büttner, Brinton Seashore‐Ludlow, Jonas Schreiner, Maike Windbergs, Martin Cornillet, Niklas K. Björkström, Andreas J. Hülsmeier, Thorsten Hornemann, Jesper V. Olsen, Yi Wang, Roberto Gramignoli, Michael Sundström, Volker M. Lauschke

“…Combined, this study presents the first patient‐derived 3D MASH model, identifies a novel signaling module with anti‐fibrotic effects, and highlights the potential of organotypic culture systems for phenotype‐based chemogenomic drug target identification at scale.…”
Get full text

Type and physical intensity of occupations at pulmonary TB diagnosis by M. Saroufim, C. Geric, A. Majidulla, A. Abjani, G. Tavaziva, S. Saeed, A.J. Khan, F. Ahmad Khan

“…DESIGN/METHODS: We did a secondary analysis of data from a study evaluating the diagnostic accuracy of artificial intelligence-based chest X-ray (CXR) analysis software, where individuals had been evaluated for active PTB using sputum cultures and had provided information on occupation. …”
Get full text

Assessing in-vitro models for microglial development and fetal programming: a critical review by Steven Schepanski, Steven Schepanski, Gonza B. Ngoumou, Gonza B. Ngoumou, Claudia Buss, Claudia Buss, Claudia Buss, Claudia Buss, Georg Seifert, Georg Seifert

“…The models examined include primary microglia cultures, microglia cell lines, iPSC-derived microglia, PBMC-induced microglia-like cells, 3D brain organoids derived from iPSCs, and Hofbauer cells. …”
Get full text

Predictive value of serum procalcitonin level for the diagnosis of bloodstream infections in hematological patients by Qi Sun, Qingsong Lin, Yanxia Lv, Zhiying Tian, Qiushuang Yan, Yaqing Yu, Xue Fu, Hongjing Yao, Fujun Sun, Yonghui Xia, Guoqing Zhu, Sizhou Feng

“…Methods We conducted a retrospective study involving 2299 cases with hematological diseases and who had been performed blood culture and PCT test within 24 h. Results For patients with hematological diseases, the serum PCT was slightly elevated in the BSI group. …”
Get full text

Retropharyngeal Abscess in Adults: Five Case Reports and Review of the Literature by A. Harkani, R. Hassani, T. Ziad, L. Aderdour, H. Nouri, Y. Rochdi, A. Raji

“…Endobuccal abscess puncture was practiced in 4 cases; only one organism was identified by culture: Staphylococcus aureus treatment was based on triple intravenous antibiotics and anti-Koch's therapy (in one case), and the surgical drainage under general anesthesia was also performed in the case of the diabetes patient which required also the correction of hyperglycemia in intensive care unit. …”
Get full text

Synbiotic microcapsule dietary supplementation for prevention against co-infection diseases in Pacific white shrimp: a limited field experiment by Munti Yuhana, Andreas Tambun, Widanarni Widanarni, Usamah Afiff

“…NP5 and mannan oligosaccharide (MOS) dietary in different feeding frequencies in Pacific white shrimp culture field experiment. The MS was administered as a feed supplementation to enhance the immunity for prevention against co-infection with WSSV (White Spot Syndrome Virus) and Vibrio harveyi. …”
Get full text

The most comprehensive history of fire activity in the Pur-Taz interfluve over the last 11,000 years (Western Siberia, Russia) by Nikita V. Shefer, Sergey V. Loiko, Ivan V. Kriсkov, Artem G. Lim

“…For the third period, a temporal relationship between fire frequency and archaeological cultures is noted. It was also established that in the second half of the Holocene in the southern tundra peat accumulation was not interrupted in fens permafrost polygonal peat plateaus. …”
Get full text