Nelfinavir Impairs Glycosylation of Herpes Simplex Virus 1 Envelope Proteins and Blocks Virus Maturation by Soren Gantt, Eliora Gachelet, Jacquelyn Carlsson, Serge Barcy, Corey Casper, Michael Lagunoff

“…Given the apparent absence of an aspartyl protease encoded by HHVs, we investigated the mechanism of action of NFV herpes simplex virus type 1 (HSV-1) in cultured cells. Selection of HSV-1 resistance to NFV was not achieved despite multiple passages under drug pressure. …”
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Inhibition of Angiogenic Factor Production from Murine Mast Cells by an Antiallergic Agent (Epinastine Hydrochloride) In Vitro by K. Asano, A. Furuta, K. Kanai, S. Sakaue, H. Suzaki, T. Hisamitsu

“…The levels of angiogenesis factors, keratinocyte-derived chemokine (KC), tumor necrosis factor-α (TNF), and vascular endothelial growth factor (VEGF) in culture supernatants, were examined by ELISA. We also examined mRNA expression for the angiogenesis factors by RT-PCR. …”
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Pelvic Actinomycosis by Alejandra García-García, Ninfa Ramírez-Durán, Horacio Sandoval-Trujillo, María del Socorro Romero-Figueroa

“…It is commonly diagnosed through a histological report, obtained after a surgery subsequent to an erroneous initial diagnosis. A bacterial culture in anaerobic medium could be useful for the diagnosis but requires a controlled technique and should be performed using specialised equipment.…”
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The involvement of reactive oxygen species in wounding-induced archeospores production in Neopyropia yezoensis by Dahai Gao, Chaofeng Teng, Xinghong Yan

“…Next, when the blade fragments were treated with ROS inhibitor diphenyleneiodonium (DPI), it showed that the production of archeopores was significantly suppressed. Under normal culturing after wounding, 78.3% of the fragments could release archeospores, and the ROS fluorescence was enriched in the released archeospores. …”
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Enhanced Production and Characterization of a Solvent Stable Amylase from Solvent Tolerant Bacillus tequilensis RG-01: Thermostable and Surfactant Resistant by Soni Tiwari, Neha Shukla, Pooja Mishra, Rajeeva Gaur

“…Ten bacterial strains isolated from the soil samples in the presence of cyclohexane were screened for amylase production. Among them, culture RG-01 was adjudged as the best amylase producer and was identified as Bacillus tequilensis from MTCC, Chandigarh. …”
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RNA Interference Targeting Snail Inhibits the Transforming Growth Factor β2-Induced Epithelial-Mesenchymal Transition in Human Lens Epithelial Cells by Ping Li, Jiaona Jing, Jianyan Hu, Tiejun Li, Yuncheng Sun, Huaijin Guan

“…This study was done to investigate the effect of Snail targeting siRNA on TGFβ2-induced EMT in human lens epithelial cells. TGFβ2 treatment of cultured human epithelial cell line (HLEB3) upregulated the expression of Snail and the EMT relevant molecules such as vimentin and α-SMA but downregulated the expression of keratin and E-cadherin. …”
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Effects of Two Salts Compounds on Mycelial Growth, Sporulation, and Spore Germination of Six Isolates of Botrytis cinerea in the Western North of Algeria by Boualem Boumaaza, Mohamed Benkhelifa, Moulay Belkhoudja

“…The sodium and calcium salts stimulated conidia production in liquid culture. We noticed that the effect of calcium chloride on sporulation was average while sodium chloride. …”
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Effect of nano- and micro-polystyrene particles on small intestinal epithelial functions and enteric neuronal activity in vitro by Kristin Elfers, Pascal Benz, Marion Burmester, Silja Hein, Kathrin Hansen, Holger Sieg, Linda Böhmert, Maxi B. Paul, Gemma Mazzuoli-Weber

“…In the current study, we aimed to investigate the effect of polystyrene particles of nano- (100 nm) and micro-size (1.0 μm), firstly, on intestinal epithelial electrophysiological processes using the Ussing chamber technique and, secondly, on enteric neuronal properties using neuroimaging on primary cultured enteric neurons. The results indicate a size-dependent impairment of epithelial integrity and electrogenic glucose transport upon particle application. …”
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Diagnostic Study of Pathogenic Bacterial Isolated from Camel’s Pneumonic lungs Slaughtered in Al-Muthanna Province Abattoir, Iraq Using Vitek2 Compactiological approach and Vitek2... by Hayder M Watban, Nabeel M Al-Maaly

“…Then, the swab samples were obtained from lungs and submitted to bacteriological cultures on both general and selective media. Additionally, microscopic examination of the bacteria using Gram staining followed by diagnosis with Vitek 2‎ system. …”
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Prevalence and Antimicrobial Susceptibility Patterns of Neisseria gonorrhoeae among Suspected Patients Attending Private Clinics in Jimma, Ethiopia by Addisu Sahile, Lule Teshager, Minale Fekadie, Mulatu Gashaw

“…Of these, 30 (96.7%) were females. High proportion of culture confirmed cases (18 (12.5%)) were observed in the 20–24 age group. …”
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Intranasally administrated fusion-inhibitory lipopeptides block SARS-CoV-2 infection in mice and enable long-term protective immunity by Said Mougari, Valérie Favède, Camilla Predella, Olivier Reynard, Stephanie Durand, Magalie Mazelier, Edoardo Pizzioli, Didier Decimo, Francesca T. Bovier, Lauren M. Lapsley, Candace Castagna, Nicole A. P. Lieberman, Guillaume Noel, Cyrille Mathieu, Bernard Malissen, Thomas Briese, Alexander L. Greninger, Christopher A. Alabi, N. Valerio Dorrello, Stéphane Marot, Anne-Geneviève Marcelin, Ana Zarubica, Anne Moscona, Matteo Porotto, Branka Horvat

“…The lipopeptides block SARS-CoV-2 infection in cell lines and lung-derived organotypic cultures. Intranasal administration in mice allows the maintenance of homeostatic transcriptomic immune profile in lungs, prevents body-weight loss, decreases viral load and shedding, and protects mice from death caused by SARS-CoV-2 variants. …”
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A large-scale dataset for Chinese historical document recognition and analysis by Yongxin Shi, Dezhi Peng, Yuyi Zhang, Jiahuan Cao, Lianwen Jin

“…Recognizing and analyzing these documents hold significant value for the research of ancient culture. Recently, researchers have tried to utilize deep-learning techniques to automate recognition and analysis. …”
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Bilateral Macular Roth Spots as a Manifestation of Subacute Endocarditis by Karolina Ceglowska, Katarzyna Nowomiejska, Agnieszka Kiszka, Michael J. Koss, Ryszard Maciejewski, Robert Rejdak

“…Procalcitonin concentration, platelet count, and body temperature were within normal ranges. A blood culture was ordered and yielded Streptococcus mitis and intravenous antibiotics were started immediately. …”
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An ingestible bioimpedance sensing device for wireless monitoring of epithelial barriers by Brian M. Holt, Justin M. Stine, Luke A. Beardslee, Hammed Ayansola, Younggeon Jin, Pankaj J. Pasricha, Reza Ghodssi

“…Addressing this technology gap, intraluminal bioimpedance sensing may be employed as a localized, non-invasive surrogate to TEER electrodes used in cell cultures. Thus far, bioimpedance has only been implemented in esophagogastroduodenoscopy (EGD) due to the need for external electronics connections. …”
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Oral Lesions Induced by Chronic Khat Use Consist Essentially of Thickened Hyperkeratinized Epithelium by Ochiba Mohammed Lukandu, Lionel Sang Koech, Paul Ngugi Kiarie

“…The habit of khat chewing is prevalent in many Middle Eastern and African cultures and has been associated with various adverse conditions in humans. …”
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Are Shared-Goal Congruence, Customer Relationship Management, and Customer Relationship Advantages Matter to Leverage Firm Performance? Indonesia Cases on Retail by Mahfudz Mahfudz, Kardison Lumban Batu, Aulia Vidya Almadanaa

“…The implementation of GSCM, supported by strong management commitment and a shift in organizational culture, enhances energy and resource efficiency, process and product innovation, environmental risk reduction, customer satisfaction, continuous improvement, and cost reductions, leading to competitive advantages through faster and more accurate decision-making.…”
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Use of UTAUT for analyzing the acceptance and use of electric scooters in the public transport system by Fernando Marroquín-Ciendúa, Manuel Medina-Labrador, Laura Camila Hurtado Méndez, Lorena Patricia Mora Hernández, Cristian Nicolás Puentes Guzmán

“….Bogotá’s Urban transport system faces critical challenges due to 80% population growth, insufficient routes, and a limited culture of solidarity. These factors exacerbate travel times, congestion, pollution, and user stress. …”
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Determination of FMDV 146S particle concentration by spectrometric method during viral RNA quantification by M. I. Doronin, D. V. Mikhalishin, V. A. Starikov, D. A. Lozovoy, Yu. S. El’kina, A. V. Borisov

“…It is an inexpensive, easy-to-perform method allowing for determination of FMDV 146S particle concentration in the non-inactivated culture suspension. 146S particle concentration was found to depend on the number of RNA molecules extracted from virions after their strain-specific immune capture and quantitatively detected by the spectrometric method. …”
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Evidence from a mouse model supports repurposing an anti-asthmatic drug, bambuterol, against Alzheimer’s disease by administration through an intranasal route by Anne-Claire Groo, Thomas Curel, Aurélie Malzert-Fréon, Line Séguy, Ophélie Bento, Sophie Corvaisier, Thomas Culerier, Romain Legrand, Noëlle Callizot, Alexandre Henriques, Georgia Culley, Sylvie Claeysen, Christophe Rochais, Patrick Dallemagne

“…The present work firstly confirmed the capacity of bambuterol to display in cellulo neuroprotective activities, reduction of Tau hyperphosphorylation and preservation of synapses in rat hippocampal neuronal cultures intoxicated with Aβ peptides. Further, bambuterol, in the form of a liposomal gel, showed a good bioavailability in CNS after intranasal administration, which should reduce any side effects linked to peripheral terbutaline release. …”
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Absence of the Genetic Marker IS6110 from a Strain of Mycobacterium tuberculosis Isolated in Ontario by Susan T Howard, Matthew T Oughton, Albert Haddad, Wendy M Johnson

“…Records indicated that the patient had emigrated from Laos circa 1990. A culture grown from a bronchoalveolar lavage specimen was identified as Mycobacterium tuberculosis by standard biochemical methods. …”
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