Fluticasone Propionate in Inflammatory Bowel Disease by Marta Carpani de Kaski, Humphery JF Hodgson

“…In particular, fluitcasone propionate is a fluorinated glucocorticoid, in which systemic side effects are absent or minimal due to its relatively low absorption and rapid first pass metabolism In an open trial in 12 patients with mild and moderately active Crohn's disease, administration of 20 mg fluitcasone propionate orally was associated with a significant fall in the Crohn's disease activity index and improvement in other parameters of inflammation, without change in either plasma cortisol levels or responsiveness to adrenocorticotropic hormone, suggesting that this drug is a promising therapy for Crohn's disease meriting evaluation against conventional corticosteroids.…”
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Oral 5-Aminosalicyclic Acid Versus 6-Methylprednisolone in Active Crohn's Disease by Jürgen Schölmerich, Harro Jenss, Franz Hartmann, Hanne Döpfer, The German 5-ASA Study Group

“…Mean age, earlier surgical intervention, localization of Crohn's disease and extraintestinal manifestations were not different in both groups. The Crohn's disease activity index (CDAI) and the van Hees index were not significantly different in both treatment groups at the entrance examination (median CDAI 232 in the 5-ASA group and 220 in the methylprednisolone group). …”
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Open Trial of Cyclosporine in Patients with Severe Active Crohn's Disease Refractory to Conventional Therapy by Kevork M. Peltekian, C. Noel Williams, Allan S. MacDonald, Peter D. Roy, Elizabeth Czolpinska

“…T he remaining 10 patients all improved within four weeks as measured by three different clinical indices: Crohn's Disease Activity Index, Simple Index of Crohn's Disease Activity and Mean Score of Therapeutic Goals (MSTG). …”
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Role of Cyclosporine in Crohn's Disease by CN Williams

“…All patients in this study had active Crohn's disease (Crohn's disease activity index greater than 150). There were 37 patients randomized to cyclosporine and 34 to placebo. …”
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Short-Term Efficacy of Exclusive Enteral Nutrition in Pediatric Crohn’s Disease: Practice in China by Youyou Luo, Jindan Yu, Hong Zhao, Jingan Lou, Feibo Chen, Kerong Peng, Jie Chen

“…Basic demographics, history, physical examination, the pediatric Crohn disease activity index (PCDAI), laboratory findings, endoscopic findings, and adverse effects were recorded. …”
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The Relationship between C-Reactive Protein/Albumin Ratio and Disease Activity in Patients with Inflammatory Bowel Disease by Yi-Han Chen, Li Wang, Shu-Yi Feng, Wei-Min Cai, Xiao-Fu Chen, Zhi-Ming Huang

“…To explore the disease activity, the Mayo score and Crohn disease activity index were used to assess UC and CD patients, respectively. …”
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Responsiveness and clinical utility of PROMIS instruments in pediatric Crohn's disease: insights from a longitudinal study by Sara Azevedo, Sara Azevedo, Maria Miguel Oliveira, Maria Miguel Oliveira, Paulo Nogueira, Paulo Nogueira, Paulo Nogueira, Ana Isabel Lopes, Ana Isabel Lopes

“…Disease activity was evaluated using the pediatric Crohn's disease activity index (PCDAI) and clinical markers. IMPACT-III was also applied. …”
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