A Real‐World Study: Therapeutic Outcomes of ROS1‐Positive Advanced NSCLC by Hanqi Yuan, Zihua Zou, Xuezhi Hao, Yan Li, Junling Li, Jianming Ying, Puyuan Xing

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Efficacy and Clinical Outcomes of Crizotinib in Patients with ROS1-Rearranged NSCLC: A Multicenter Study by Alper Topal, Goncagul Akdag, Sedat Yildirim, Oguzcan Kinikoglu, Deniz Isik, Gizem Yildirim, Salih Tunbekici, Fatih Kus, Aydın Acarbay, Murad Guliyev, Nargiz Majidova, Yasin Kutlu, Mustafa Erman, Hatice Odabas, Nedim Turan, Nuri Karadurmus

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CLINICAL EFFICACY OF TARGETED THERAPY TOWARDS METASTATIC LUNG CANCER CARRYING DISTINCT TYPES OF ALK REARRANGEMENTS by N. V. Mitiushkina, I. A. Stepanov, D. O. Yurlov, E. A. Filippova, S. V. Odintsova, A. M. Lozhkina, S. V. Orlov, A. G. Iyevleva

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Inflammatory myofibroblastic tumors in children: clinical characteristics and treatment outcomes with a focus on targeted therapies by Ülkü Miray Yıldırım, Rejin Kebudi, Bülent Zülfikar, Bilge Bilgiç

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Novel PLEC-EML4-ALK Double Fusion Underlying Crizotinib Resistance in a Metastatic Inflammatory Myofibroblastic Tumor: A Case Report by Alessandra Maleddu, MD, Trista K. Hinz, MS, Margaret A. Black, MD, Dara L. Aisner, MD, PhD, Carrie B. Marshall, MD, Anthony D. Elias, MD, Breelyn A. Wilky, MD, Lynn E. Heasley, PhD, Kurtis D. Davies, PhD

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Case Report: A rare case of MET-amplified gastric cancer with systemic metastasis: remarkable efficacy of crizotinib and the role of precision medicine by Yan Shen, Yan Shen, Yaxin Xu, Yaxin Xu, Jing Sun, Jing Sun

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Rational design, and synthesis of imidazole ring incorporated Pyridine-1,2,4-oxadiazole derivatives: In-vitro anticancer evaluation and in-silico molecular docking simulations by Rambabu Vasamsetti, Naresh Babu Gatchakayala, Nekuri Bujjibabu, Vudi Sanjeeva Kumar, Tirri Veera Venkata Satyanarayana, Gundu Pavani, Ravi Kumar Kapavarapu, Bandaru Madhav

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Response to crizotinib in advanced intrahepatic cholangiocarcinoma with ZKSCAN1-MET fusion and MET amplification: case reports and literature review by Jian-Hui Wu, Yu-ze Fan, Jing Sun, Xue-Zhang Duan

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A Phase Ia/b study of MEK1/2 inhibitor binimetinib with MET inhibitor crizotinib in patients with RAS mutant advanced colorectal cancer (MErCuRIC) by Francesca Aroldi, Elena Elez, Thierry André, Geraldine Perkins, Hans Prenen, Vlad Popovici, Peter Gallagher, Jennifer Houlden, Linda Collins, Corran Roberts, Christian Rolfo, Federica Di Nicolantonio, Margaret Grayson, Ruth Boyd, Karolien Bettens, Jurgen Delfavero, Victoria Coyle, Mark Lawler, Hajrah Khawaja, Pierre Laurent-Puig, Manuel Salto-Tellez, Tim S. Maughan, Josep Tabernero, Richard Adams, Robert Jones, Bryan T. Hennessy, Alberto Bardelli, Marc Peeters, Mark R. Middleton, Richard H. Wilson, Sandra Van Schaeybroeck, on behalf of the MErCuRIC Trial Consortium

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Crizotinib-Related Aseptic Abscesses in Lung Adenocarcinoma and <i>ROS1</i>-Gene Rearrangement: A Case Report by Thamires Oliveira-Silva, Camila Naegele-Bazzanella, Mauro Zukin, Nicolle Cavalcante, Antônio Alexandre de-Oliveira-Siciliano, Jaime Araújo-Oliveira-Neto, Clarissa Baldotto

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MET exon 14 skipping mutations in non-small-cell lung cancer a 3 years screening experience by R. Ben Dhiab, R. Loyaux, S. Garinet, M. Bastide, S. Léonard-Goyet, Elizabeth Fabre, Audrey Mansuet-Lupo, Laure Gibault, S. Jouveshomme, E. Giroux-Leprieur, K. Leroy, M. Wislez, H. Blons

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Late‐Onset Crizotinib‐Associated Renal Cysts With Subsequent Regression Following Dose Reduction: A Case Report by Joon‐Young Yoon, Won Gi Jeong, Yoo‐Duk Choi, Seung Ji Kang, Hwa Kyung Park, Hyung‐Joo Oh, Cheol‐Kyu Park, In‐Jae Oh, Young‐Chul Kim

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Utility of combined solid and liquid biopsy for molecular profiling in lung adenocarcinoma: Insights from a real-world case by Bharat Bhosale, Gunj Bafna, Paridhy Vanniya Subramanyam, Kapil Salgia, Sadia Afreen, Jinumary John, Vyomesh Javle, Kritika Verma, N.R. Naavarasi, Sreekanth Reddy Peddagangannagari, Akhil Gorla, Giridharan Periyasamy, Kshitij Rishi, Hitesh Goswami, Vidya H. Veldore

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ALK-positive large B-cell lymphoma: A study of six cases from an oncopathology center in North India by Ajita Verma, Zachariah Chowdhury, Anil Singh, Abhinav Kant, Anil Yadav, Shashikant C.U. Patne

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Crizotinib Treatment for Lorlatinib-resistant MET-amplified EML4-ALK-fusion Positive Advanced Lung Adenocarcinoma: A Case Report by Xinyi WANG, Ning MU, Mei LIU, Yue XU, Shengnan WU, Huan LV, Chunhua MA

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Rare giant epithelioid inflammatory myofibroblastic sarcoma of the abdominal cavity in a child: a case report and review of the literature by Jinzhou Li, Haixing Su, Sheng Zhang, Xianyun Chen, Chongzhi Hou, Tao Cheng

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MiR-181a-driven downregulation of cholesterol biosynthesis through SREBP2 inhibition suppresses uveal melanoma metastasis by Rui Wang, Claudia Gilbert, Houda Tahiri, Chun Yang, Solange Landreville, Pierre Hardy

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Remarkable response to crizotinib in a patient with advanced lung adenocarcinoma harboring the MPRIP-ROS1 fusion gene: A case report by Yasuyuki Kishikawa, Kohei Otsubo, Daisuke Shibahara, Yoshimasa Shiraishi, Yasuto Yoneshima, Eiji Iwama, Isamu Okamoto

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An Isolated Cutaneous Relapse in a Known Case of Systemic ALK-Positive Anaplastic Large Cell Lymphoma: A Rare Case Report with Review of Literature by Monisha Shetty, Banavasi Shanmukha Girisha, Sona C. Gowda, Vijith Shetty

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A new ALK inhibitor overcomes resistance to first‐ and second‐generation inhibitors in NSCLC by Yue Lu, Zhenzhen Fan, Su‐Jie Zhu, Xiaoxing Huang, Zhongji Zhuang, Yunzhan Li, Zhou Deng, Lei Gao, Xuehui Hong, Ting Zhang, Li Li, Xihuan Sun, Wei Huang, Jingfang Zhang, Yan Liu, Baoding Zhang, Jie Jiang, Fu Gui, Zheng Wang, Qiyuan Li, Siyang Song, Xin Huang, Qiao Wu, Lanfen Chen, Dawang Zhou, Jianming Zhang, Cai‐Hong Yun, Liang Chen, Xianming Deng

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