The methyl-CpG binding domain 2 regulates peptidylarginine deiminase 4 expression and promotes neutrophil extracellular trap formation via the Janus kinase 2 signaling pathway in e... by Biao Peng, Mu-Yun Yan, Yun-Rong Chen, Fei Sun, Xu-Dong Xiang, Da Liu

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Potential drug targets for asthma identified through mendelian randomization analysis by Xingxuan Chen, Yu Shang, Danting Shen, Si Shi, Zhe Wen, Lijuan Li, Hong Chen

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Comparison of the Impact of tNGS with mNGS on Antimicrobial Management in Patients with LRTIs: A Multicenter Retrospective Cohort Study by Li D, Li Q, Huang Z, Wu W, Fan X, Liu J, Li R, Zhang Q, Su X

“…Dan Li,1– 3,* Qingling Li,4,* Zhen Huang,2 Wenhao Wu,2 Xinyuan Fan,2 Jing Liu,2 Ruoran Li,2 Qi Zhang,2 Xin Su1 1Department of Respiratory and Critical Care Medicine, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, Jiangsu, 210000, People’s Republic of China; 2Department of Respiratory and Critical Care Medicine, Xuzhou Central Hospital, Xuzhou, Jiangsu, 221000, People’s Republic of China; 3Department of Respiratory and Critical Care Medicine, Jinling Hospital, Nanjing Medical University, Nanjing, 210002, People’s Republic of China; 4Department of Respiratory and Critical Care Medicine, Xuzhou First People’s Hospital, The Affiliated Xuzhou Municipal Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xin Su, Department of Respiratory and Critical Care Medicine, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, Jiangsu, 210000, People’s Republic of China, Email suxinjs@163.com Qi Zhang, Department of Respiratory and Critical Care Medicine, Xuzhou Central Hospital, Xuzhou, Jiangsu, 221000, People’s Republic of China, Email zhangqi1107@126.comBackground: tNGS and mNGS are valuable tools for diagnosing pathogens in lower respiratory tract infections (LRTIs), which subsequently influence treatment strategies. …”
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Compassionate Use of Omadacycline in a Down Syndrome Pre-Schooler With Critically Ill Atypical Pneumonia Caused by Macrolide-Resistant Mycoplasma Pneumoniae by Wu D, Xie FJ, Wang YJ, Jiang XH, Zhang GL, Zhang H, Zhu YC, Zhang Y, Tang YJ, Lin YL, Xu JX, Zhang JN, Liu BW, Kang K, Gao Y

“…Di Wu,1,* Feng-Jie Xie,2,* Ya-Jun Wang,3,* Xiao-Hui Jiang,1,* Guo-Li Zhang,3,* Hong Zhang,2 Yu-Cheng Zhu,4 Yan Zhang,4 Yu-Jia Tang,1 Yi-Lu Lin,1 Jia-Xi Xu,5 Jia-Ning Zhang,5 Bo-Wen Liu,5 Kai Kang,5 Yang Gao1 1Department of Critical Care Medicine, The Sixth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China; 2Department of Critical Care Medicine, The Hongqi Hospital Affiliated to Mudanjiang Medical University, Mudanjiang, Heilongjiang Province, People’s Republic of China; 3Department of Pediatrics, The Sixth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China; 4Department of Critical Care Medicine, The Hongxinglong Hospital of Beidahuang Group, Shuangyashan, Heilongjiang Province, People’s Republic of China; 5Department of Critical Care Medicine, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Kai Kang, Department of Critical Care Medicine, The First Affiliated Hospital of Harbin Medical University, 23 Youzheng Street, Nangang District, Harbin, Heilongjiang Province, 150001, People’s Republic of China, Tel +86-13904618016, Email janekk79@126.com Yang Gao, Department of Critical Care Medicine, The Sixth Affiliated Hospital of Harbin Medical University, 998 Aiying Road, Songbei District, Harbin, Heilongjiang Province, 150027, People’s Republic of China, Tel +86-13045160709, Email gaoyang0312@126.comBackground: Rapid and accurate identification of causative organisms and prompt initiation of pathogen-targeted antibiotics are crucial for managing atypical pneumonia. …”
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LIPS and PaO2/FiO2 Combined Plasma Biomarkers Predict Onset of Acute Respiratory Distress Syndrome in Patients of High Risks in SICU: A Prospective Exploratory Study by Ziyuan Shen, Zhongnan Yin, Senhao Wei, Zhukai Cong, Feng Zhao, Hua Zhang, Xi Zhu

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Elevated Blood Urea Nitrogen-to-Serum Albumin Ratio as a Factor That Negatively Affects the Mortality of Patients with Hospital-Acquired Pneumonia by Ding-Yun Feng, Yu-Qi Zhou, Xiao-Ling Zou, Mi Zhou, Hai-Ling Yang, Xiao-Xia Chen, Tian-Tuo Zhang

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Angiopoietin-2 and D-dimer add prognostic information to clinical risk in pulmonary arterial hypertension by Heather L. Clark, Daniel Lachant, Allison N. Light, Deborah Haight, Samia Lopia, Nigel Mackman, R. James White

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Impact of HACOR Score on Noninvasive Ventilation Failure in Non-COPD Patients with Acute-on-Chronic Respiratory Failure by Min Ding, Xiaoli Han, Linfu Bai, Shicong Huang, Jun Duan

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Symptom network analysis of insomnia-depression-anxiety-stigma in tuberculosis patients by Xiangmin Liu, Xue Qiu, Huizhen Lan, LiuYue Diao, Wei Huang, Yan Wen, Mei Feng, Mei Feng, Xiangdong Tang

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Genetic evidence for the causal effect of clonal hematopoiesis on pulmonary arterial hypertension by Jia-Yong Qiu, Shen-Shen Huang, Chao Liu, Dong Ding, Yan-Hong Xu, Yi-Min Mao, Ya-Dong Yuan

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Identification of unmet information needs among families of critically ill patients and their association with post-intensive care syndrome-family: protocol for a single-center cro... by Yoshiyasu Ito, Takuro Hamaguchi, Masatomo Suzuki, Yasushi Otaka, Mariko Asai, Yukihiro Sakaguchi, Yuki Shirai, Eisho Yoshikawa, Amane Tateno, Shoji Yokobori

“…The participants will include family members of patients admitted to the emergency ICU of the Department of Emergency and Critical Care Medicine, Nippon Medical School Hospital in Japan. …”
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Long term survival of advanced hepatoid adenocarcinoma of lung secondary to idiopathic pulmonary fibrosis: a case report by Xiaoli Wang, Xiaoli Wang, Nan Wei, Nan Wei, Huizhen Yang, Huizhen Yang, Xiaoyan Wang, Xiaoju Zhang, Xiaoju Zhang, Qianqian Zhang, Qianqian Zhang

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Preliminary evidence of immune infiltration and neutrophil degranulation in peripheral blood of non-obese OSA patients related to cognitive decline by Qingqing Liu, Yanru Ou, Ting Liu, Yuming He, Xiangming Quan, Ruoyun Ouyang, Zhihui Shi

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Special Staining of the Liquid-Based Cytopathology Test in Bronchoalveolar Lavage Fluid for Diagnosis of Invasive Pulmonary Aspergillosis with Nonneutropenic Patients by Yue Hu, Lin Zheng, Deng Pan, Lei Shao, Xianfa Xu, Yiming Yu, Qidong Zhuang, Zaichun Deng, Zhongbo Chen

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Antipsychotic prescribing practices and patient, family member and healthcare professional perceptions of antipsychotic prescribing in acute care settings: a scoping review protoco... by Zahinoor Ismail, Daniel Niven, Kirsten Fiest, Lisa Burry, Karla D Krewulak, Natalia Jaworska, Stephana Julia Moss, Zara Stelfox

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Research hotspots and future trends in sepsis-associated acute kidney injury: a bibliometric and visualization analysis by Xing-Yue Chen, Li-Jia Zhi, Jun Chen, Rong Li, Kun-Lan Long

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MVK, induced by Kras, represses cGAS-Sting signalling in lung adenocarcinoma by Changsheng Zhou, Jia Liu, Xudong Hu, Lu Lu, Juan Hou, Jian Wang, Liqun Jiang, Shuangshuang Huang, Yu Lin, Luyao Liu, Lingling Cui, Yiqian Liu, Yufeng Huang

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Sodium butyrate regulates macrophage polarization by TGR5/β-arrestin2 in vitro by Miao Liu, Wen-jie Xie, Xu Zhang, Wei Wu, Guang Li, Lu Wang

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The Association between Standardized Serum 25-Hydroxyvitamin D Concentration and Risk of Anemia: A Population-Based Cross-Sectional Study by Yang Zhang, Xiaotong Wang, Jia Wang, Weiwei Hu, Xiaolu Song, Ding Yuan, Xianliang Yan

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The impact of the COVID-19 pandemic on mental coping and emergency ability of public health emergency in COVID-19 department healthcare workers in ICU nurses of Beijing in China by Tiantian Gai, Yin He, Ying Yin, Yu Cui, Qiuping Li, Yanzhen Hu, Zhenhui Lu

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