Target miRNA identification for the LPL gene in large yellow croaker (Larimichthys crocea) by Kalim Ullah, Aslam Hossain, Mingyue Cao, Liangyi Xue, Yajun Wang

“…Subsequent in-depth analysis further implicated these miRNAs, along with miR-891a, as prospective targets of LPL, suggesting their integral involvement in the regulation of this critical enzyme. Validation of these bioinformatics predictions was conducted through the construction of double luciferase reporters concealing the LPL 3′ untranslated region (3′UTR), substantiating that miR-84a and miR-1231-5p can modulate LPL expression via the LPL 3′UTR. …”
Get full text

Prevalence of Early Postnatal-Care Service Utilization and Its Associated Factors among Mothers in Hawassa Zuria District, Sidama Regional State, Ethiopia: A Cross-Sectional Study by Shambel Yoseph, Azmach Dache, Aregahegn Dona

“…A postnatal care given after childbirth is a critical care to promote health and to prevent complications of the mother and newborn. …”
Get full text

Mechanisms of (Fisch.) Bge. var. mongholicus (Bge.) Hsiao (huang qi) and (Oliv.) Diels (dang gui) in Ameliorating Hypoxia and Angiogenesis to Delay Pulmonary Nodule Malignant Tra... by Ying Guo PhD, Peng Yang MS, Zihong Wu PhD, Sanyin Zhang PhD, Fengming You PhD

“…This review explores the critical roles of hypoxia and angiogenesis in the transition from PN to LC. …”
Get full text

Understanding barriers to young people’s utilisation of sexual and reproductive health services in Asia-Pacific countries: a qualitative systematic review and thematic synthesis by Daniel Mackay, Benjamin Gregory, Evi Germeni, Watcharakorn Riabroi

“…We assessed the quality of identified studies using the Critical Appraisal Skills Programme qualitative checklist and employed a thematic synthesis approach for the data analysis.Results We included 31 articles that reported the experiences of over 1800 young people from 15 different countries. …”
Get full text

Microbial Safety of Sachet Water in Ghana: A Systematic Review by Wisdom K Ahiabor, Eric S Donkor

“…Conclusion: This study highlighted critical public health risks associated with sachet water in Ghana, particularly the presence of harmful bacteria and parasites. …”
Get full text

A Framework for Fourth Industrial Revolution Adoption by Small-Scale Rural Farmers in Sub-Saharan Africa: A Systematic Literature Review by Willard Munyoka, Nkhangweni Lawrence Mashau, Modimowabarwa Kanyane

“…A systematic literature review approach is employed to identify critical components significant for adopting 4IR in rural farming. …”
Get full text

Rhetorical function of sentence moods in Garshaspnamehpoem and the story of Bijan and Manizheh from Shahnameh by Yahya Talebian, Gholamreza Mastali Parsa, Hamid Amini Asalemi

“…In western linguistics, modern critics and linguists such as Michael Halliday and Roger Fowler have also introduced the mood of the sentence more extensively than traditional rhetoric, examining it as the most important element in the interactive function of language. …”
Get full text

Spatial-Temporal Variation of Population Aging: A Case Study of China’s Liaoning Province by Dunyi Guan, Lei Lei, Zenglin Han

“…With the rapid increase of the aging population in China, research on the aging phenomenon has become critical. Studying population aging from a spatial perspective is of vital practical significance. …”
Get full text

LitSpatz: An App for Literary Walks to Promote and Record Primary Students' Text Comprehension, Perspective Taking and Related Skills by Nora Heyne, Maximilian Pfost, Peter Kuntner

“… Teaching listening and reading skills including abilities to adopt spatial and affective perspectives of literary figures and to reflect critically on texts regarding one's own world are central goals of primary school education in Germany, Europe, and beyond. …”
Get full text

Dengue severity by serotype and immune status in 19 years of pediatric clinical studies in Nicaragua. by Federico Narvaez, Carlos Montenegro, Jose G Juarez, José Victor Zambrana, Karla Gonzalez, Elsa Videa, Sonia Arguello, Fanny Barrios, Sergio Ojeda, Miguel Plazaola, Nery Sanchez, Daniel Camprubí-Ferrer, Guillermina Kuan, Gabriela Paz Bailey, Eva Harris, Angel Balmaseda

“…<h4>Conclusions</h4>These findings demonstrate differences in dengue severity by serotype and immune status and emphasize the critical need for a dengue vaccine with balanced effectiveness against all four serotypes, particularly as existing vaccines show variable efficacy by serotype and serostatus.…”
Get full text

An Open Letter on Advancing HIV prevention: Augmenting an ecosystem-based approach to understand prevention decision-making [version 2; peer review: 2 approved] by Rosemary Pierce-Messick, Nishan Gantayat, James Baer, Alok Gangaramany

“…As HIV incidence declines and biomedical advances continue, it will become critical for public-health practitioners to reach key and at-risk populations with prevention services and limit primary transmission. …”
Get full text

The presence of risk factors in the home environment that influences the fall of people of the third age by Ratko Zlatičanin, Amila Jaganjac, Arzija Pašalić, Amra Mačak Hadžiomerović

“…A comprehensive assessment of fall risk is critical to the development of effective fall prevention programs. …”
Get full text

How mothers with severe emotion dysregulation use DBT skills in parenting contexts: observational coding of skills use in a DBT skills training group by Yoel Everett, Olivia A. Frigoletto, Jacqueline R. O’Brien, Amy L. Byrd, Stephanie D. Stepp, Maureen Zalewski

“…Abstract Background Dialectical Behavior Therapy’s (DBT) well established effectiveness in reducing emotion dysregulation, and the growing recognition that parental emotion regulation is critical to effective parenting has led to increasing interest in the applicability of DBT skills to parenting. …”
Get full text

Navigating the Challenges of Sustainability in the Food Processing Chain: Insights into Energy Interventions to Reduce Footprint by Orlando Corigliano, Pietropaolo Morrone, Angelo Algieri

“…This review paper examines the critical intersection of energy consumption and environmental impacts within the global food system, emphasizing the substantial footprint (including land usage, costs, food loss and waste, and carbon and water footprints) associated with current practices. …”
Get full text

Identification of KIFC1 as an independent prognostic marker in renal clear cell carcinoma correlates with tumor proliferation and immune infiltration by Bin Du, Jia Wang, Jinping Zheng, Jing Huo, Pu Wang

“…Kinesin-like protein (KIFC1), a critical factor in maintaining the stability of the microtubule system, has significant prognostic value in some tumors. …”
Get full text

The Influence of Lifestyle Modifications on Cardiovascular Outcomes in Older Adults: Findings from a Cross-Sectional Study by Mohammed Almutairi, Ashwaq A. Almutairi, Abdulaziz M. Alodhialah

“…The path analysis highlighted dietary quality and physical activity as critical mediators of cardiovascular health improvements. …”
Get full text

A De Novo Mutation in ACTC1 and a TTN Variant Linked to a Severe Sporadic Infant Dilated Cardiomyopathy Case by Jose G. Acuña-Ochoa, Norma A. Balderrábano-Saucedo, Ana C. Cepeda-Nieto, Maria Y. Alvarado-Cervantes, Vianca L. Ibarra-Garcia, Daniel Barr, Matthew J. Gage, Ryan Pfeiffer, Dan Hu, Hector Barajas-Martinez

“…These results may increase the known clinical pathogenic variations that may critically alter the structure of the heart, whose fatality could be prevented when rapidly detected.…”
Get full text

Anatomical characteristics of mitral isthmus and its spatial relationship with the esophagus in patients undergoing atrial fibrillation ablation using CT angiography by Yilin Pan, Yilin Pan, Hong Zeng, Xin Liu, Xiaohang Fu, Liyuan Pan, Yanjing Wang

Get full text

Pooled prevalence and subgroup variations of Tetralogy of Fallot among children and adolescents with congenital heart defect in Sub-Saharan Africa: A systematic review and meta-ana... by Biniam Endale Geleta, Abay Mulu

“…<h4>Background</h4>Tetralogy of Fallot is one of the critical congenital heart defects needing intervention within the first year of life.…”
Get full text

Wind turbine blade damage detection based on acoustic signals by Chenchen Yang, Shaohu Ding, Guangsheng Zhou

“…Abstract In recent years, the size of wind turbine blades has increased, underscoring the critical importance of monitoring their structural health. …”
Get full text