CINNAMON-GUI: Revolutionizing Pap Smear Analysis with CNN-Based Digital Pathology Image Classification [version 1; peer review: 2 approved] by Luca Zammataro

“…Feature mapping highlighted critical morphological aspects, improving classification accuracy. …”
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Plantar sensation associates with gait instability in older adults by Jason R. Franz, Andrew D. Shelton, Kota Z. Takahashi, Jessica L. Allen

“…These results should build confidence that interventions designed to improve plantar sensation for older adults, possibly through insoles or footwear modifications, could be critical for reducing gait-related falls in at-risk populations.…”
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Potential molecular and cellular mechanisms for adverse placental outcomes in pregnancies complicated by SARS-CoV-2 infection-A scoping review. by Janelle Y Wai, Eilidh M Wood, Kylie K Hornaday, Donna M Slater

“…With a rapid expansion of literature on this topic, it is critical to assess the quality and synthesize the current state of literature. …”
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E6AP is essential for the proliferation of HPV-positive cancer cells by preventing senescence. by Alicia Avenhaus, Milica Velimirović, Julia Bulkescher, Martin Scheffner, Felix Hoppe-Seyler, Karin Hoppe-Seyler

“…Our results further indicate that interfering with E6AP expression or function could result in therapeutically desired effects in HPV-positive cancer cells by efficiently inducing an irreversible growth arrest. Since the critical role of the E6/E6AP/p53 complex for viral transformation is conserved between different oncogenic HPV types, this approach could provide a therapeutic strategy, which is not HPV type-specific.…”
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Achieving Sustainability in Manufacturing Micro, Small and Medium Enterprises (MSMEs’) in Tanzania Through Adoption of Solar Energy by Felichesmi Lyakurwa

“…The results therefore, provides critical information to policy making institutions in Tanzania to make informed decisions on the formulation of national strategies that attracts use of renewable energy for manufacturing sustainability.…”
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Rethinking methane from animal agriculture by Shule Liu, Joe Proudman, Frank M. Mitloehner

“…Abstract Background As the global community actively works to keep temperatures from rising beyond 1.5 °C, predicting greenhouse gases (GHGs) by how they warm the planet—and not their carbon dioxide (CO2) equivalence—provides information critical to developing short- and long-term climate solutions. …”
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Numerical study on the surface evolution and flow dynamics in laser polishing of 100Cr6 steel based on the coupled capillary and thermocapillary flow by Chuqiao Fang, Wei Dai, Xiao Wu, Sijin Wang

“…This study highlights the critical role of thermal input in LP and discusses how adjusting laser process parameters effectively controls this input. …”
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Debates on the Role of the U.S. Theater Missile Defense in the Regional Deterrence of North Korea and Iran by O. O. Krivolapov

“…According to the second approach, the regional missile defense may destabilize the situation in the region without enhancing the protection of the U.S. and their allies’ armed forces.The third section provides a critical analysis of the debate. The author concludes that the arguments and assessments of both the opponents and proponents of the deterrence of the DPRK and Iran by means of regional missile defense are theoretically ill-founded and often one-sided. …”
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Healthcare Delivery among Yoruba Bonesetters in Southwest Nigeria and the Need for Collaboration with Orthodox Orthopedic Healthcare Services: A Mixed Method Study by Soladoye S. Asa, Matthew O. Ilori, Lawrence A. Akinyoola

“…Other issues considered critical by the doctors in the management of fractures by TBS included lack of training in the biology of bones (86.7%) and inability to refer cases to modern health facilities (73.3%). …”
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La educación ambiental en jardines botánicos. Un estado del conocimiento ante los desafíos socioambientales by Daniela Patricia Arreola A. Flores, Laura Odila Bello Benavides

“…To develop its work and educational and environmental relevance towards critical and sociocultural approaches, greater efforts and projects in educational research and environmental education are necessary. …”
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A longitudinal bottom-up analysis of staff travel patterns (2018–2023) at a research-intensive university hospital by N. Gebhardt, O. A. Kern, L. Schwaab, H.-C. Friederich, C. Nikendei

“…Academic air travel, the internationalization of research activities, and extensive travel behavior by senior staff should be critically assessed. Doctors and researchers are considered the most trustworthy professions worldwide and could lead transformations towards sustainable travel behavior.…”
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Effects of water level changes on the hydrological connectivity and water quality of a lake-type wetland by Yemiao Lin, Junfeng Dai, Xinyue Peng, Zheqing Li, Zupeng Wan

“…Future research could consider increasing the monitoring frequency during critical periods of rapid hydrological change, such as rainfall-runoff events, to capture more precise and detailed hydrological and water quality data. …”
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Sawdust as an ameliorant to decontaminate Arsenic in potato soils by Md. Hossain, Tuhin Roy, Maruf Mostofa

“…Conclusion Therefore, Potato growers can produce Potato in 25 mg/kg Arsenic contaminated soil treated with 10 g sawdust/kg soil, which contains a minimum than the critical level of Arsenic for human consumption.…”
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A hybrid deep learning air pollution prediction approach based on neighborhood selection and spatio-temporal attention by Gang Chen, Shen Chen, Dong Li, Cai Chen

“…Abstract Air pollution is a critical global environmental issue, further exacerbated by rapid industrialization and urbanization. …”
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How to get over with medication errors underestimation? Improving indices of medication errors with focus on intravenous medications in hematopoietic stem cell transplantation sett... by Ava Mansouri, Kiana Moazzeni, Maryam Valeh, Kazem Heidari, Molouk Hadjibabaie

“…Especially, in the hematopoietic stem cell transplantation (HSCT) setting where toxic drugs are frequently used and patients are in critical immunocompromised conditions, medication errors (ME) can have catastrophic reactions and devastating outcomes such as death. …”
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Government Support and Local Residents’ Behavior in E-waste Management: Evidence from Thailand by Peeranart Kiddee, Somsiri Decharat, Suttiporn Bunmak

“… Electronic waste (e-waste) management is a critical global pollution concern. This study investigates government support; local residents' perceptions, knowledge, attitudes, and behaviors related to e-waste management; and collaborative governance in southern Thailand. …”
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IRF3 Promotes Production of IL-6 and Nitric Oxide but Represses CCL22 in RAW264.7 Macrophage Cells Exposed to Lipopolysaccharides in Culture by Moore TC, Pinkerton TS, Petro TM

“…Restoration of IRF3 expression in IRF3KO RAW cells increased IL-6, restored NO, and decreased CCL22 production in response to LPS of E. coli.Discussion: Therefore, IRF3 is critical to the expression of pro- and anti-inflammatory factors produced by macrophages responding to LPS and could be a target during periodontitis treatment.Keywords: IRF3, lipopolysaccharide, macrophages, RAW264.7 cells, cytokines…”
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Impact of nutrient dynamics on chlorophyll-a concentrations in non-interconnected lakes: A study in the Vellore and Chennai region by Raghul Mageswaran, Porchelvan Ponnusamy

“…Spatial distribution maps for 2024 indicate that sample 1 from each lake showed higher turbidity, chlorophyll-a, total phosphate, and total nitrate, implying these parameters are critical drivers of eutrophication. Among the lakes, Kaveripakkam exhibited the highest values for these parameters, which needs management strategies. …”
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Urban Park Planning for Sustainability: Resident Insights from China’s Major Cities by Biao He, Siyu Wang, Qian Xiong, Zheng Zhao, Yilei Hou

“…Comparative analysis showed significant variations in the preferences in different resident groups, with Chaoyang Park facing a sense of deprivation due to weaker natural features, suggesting the critical role of natural elements in park design, while Century and Yuexiu Parks were highly valued for aligning park design with local needs and preferences. …”
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Application of a theoretical simulator to the optimisation of risk-based invasive species surveillance by Thomas I. Gibson, Rebecca S. Millard, Isla MacMillan, Nick Taylor, Mark Thrush, Hannah Tidbury

“…Early detection and rapid response are critical to the successful management of non-indigenous species (NIS) and rely on effective surveillance programmes. …”
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