Salivary Levels of Interleukin-17 in Iranian Patients With Systemic Sclerosis by Ali Tadayon, Javad Moayedi, Mohamad Ali Nazarinia, Mahyar Malekzadeh, Sara Kazemi, Maryam Mardani

“…Interleukin-17 (IL-17) is a potent pro-inflammatory cytokine produced by T helper 17 (Th17) cells, and plays a critical role in many inflammatory conditions. This study aims to assess the salivary IL-17 levels in Iranian patients with SSc. …”
Get full text

Investigating the Effectiveness of Technology-Enhanced Language Learning Tools in Supporting Second Language Acquisition by Christiana Darkoah, Levina Nyameye Abunya, Edward Owusu, Victoria Ogunnike Faleke

“…The paper highlights the critical role of technological tools in SLA among young learners, shedding light on how access to and effective use of technology can improve vocabulary and communication skills.…”
Get full text

CHOLINE TRANSPORTER-RELATED 4 (CTR4) Is Involved in Drought and Saline Tolerance in Rice by Yu Shicong, Luo Ruxian, Zheng Shuqin, Ning Jing, Shi Yuanzhu, Guo Daiming, Jia Liangmeng, Wang Sen, Xiao Guizong, Guo Pengwang, Li Yang, Ma Xiaoding

“…Using MutMap sequencing, we characterized the role of a choline transporter-related family gene, CTR4 (Choline Transporter-Related 4), in rice’s tolerance to drought and salt stress. CTR4 plays a critical role in regulating membrane lipid synthesis. …”
Get full text

The endonuclease activity of MCPIP1 controls the neoplastic transformation of epithelial cells via the c-Met/CD44 axis by Paulina Marona, Rafał Myrczek, Iga Piasecka, Judyta Gorka, Oliwia Kwapisz, Ewelina Pospiech, Janusz Rys, Jolanta Jura, Katarzyna Miekus

“…These findings highlight the critical role of MCPIP1 RNase activity in modulating the c-Met/CD44 axis, thereby influencing stemness and tumorigenesis.…”
Get full text

IL-6-Inducing Peptide Prediction Based on 3D Structure and Graph Neural Network by Ruifen Cao, Qiangsheng Li, Pijing Wei, Yun Ding, Yannan Bin, Chunhou Zheng

“…IL-6-inducing peptides are critical for the development of immunotherapy and diagnostic biomarkers for some diseases. …”
Get full text

The multidrug-resistant Candida auris, Candida haemulonii complex and phylogenetic related species: Insights into antifungal resistance mechanisms by Lívia S. Ramos, Pedro F. Barbosa, Carolline M.A. Lorentino, Joice C. Lima, Antonio L. Braga, Raquel V. Lima, Lucas Giovanini, Ana Lúcia Casemiro, Nahyara L.M. Siqueira, Stefanie C. Costa, Célia F. Rodrigues, Maryam Roudbary, Marta H. Branquinha, André L.S. Santos

“…Notably, C. auris is classified in the critical priority group on the World Health Organization's fungal priority pathogens list, which highlights fungal species capable of causing systemic infections with significant mortality and morbidity risks as well as the challenges posed by their MDR profiles, limited treatment and management options. …”
Get full text

Recurrent Thymic Carcinoma Treated With Median Sternotomy, Innominate Vein Replacement for Superior Vena Cava, and Iodide Implantation: A Case Report and Review of the Literature by Zhong‐zheng Chen, Wen‐dong Qu, Xing‐shu Zhang, Yong‐xiang Song

“…These tumors can exhibit aggressive behavior and may involve surrounding critical structures, such as the superior vena cava. …”
Get full text

New Data on Breeding Strategies and Reproductive Success of the Globally Threatened Turtle Dove Co-Occurring with the “Competitive” Collared Dove and the “Predatory” Maghreb Magpie... by Wafae Squalli, Ismail Mansouri, Driss Ousaaid, Mohammed Hmidani, Hamid Achiban, Fatima Fadil, Mohamed Dakki

“…Interactions between co-occurring species, including competition and predation, comprise critical processes regulating local community structure, habitat use, and diversity. …”
Get full text

Retrospective Research of Clinical and Hematological Changes Occurred by del Nido Cardioplegia in the Perioperative Period of Patients who Underwent Open-Heart Surgery by Abdullah Özer, Başak Koçak, Mustafa Arslan, Elif Şimşek, Aycan Özdemirkan, Yusuf Ünal, Erkan İriz, Hakan Zor, Levent Oktar

“…Conclusion: We found significant changes in different parameters critical for the perioperative period of open-heart surgery. …”
Get full text

SumGPT: A Multimodal Framework for Radiology Report Summarization to Improve Clinical Performance by Tipu Sultan, Mohammad Abu Tareq Rony, Mohammad Shariful Islam, Samah Alshathri, Walid El-Shafai

“…Radiology report summarization plays a critical role in medical imaging, addressing the growing need for concise and accessible interpretation of complex radiology findings. …”
Get full text

Interplay between circulating von Willebrand factor and neutrophils: implications for inflammation, neutrophil function, and von Willebrand factor clearance by Alua Kuanyshbek, Hamideh Yadegari, Jens Müller, Nasim Shahidi Hamedani, Samhitha Urs Ramaraje, Johannes Oldenburg

“… Von Willebrand factor (VWF) plays a critical role in hemostasis, and emerging evidence suggests its involvement in inflammation. …”
Get full text

Development of a prognostic model based on four genes related to exhausted CD8+ T cell in triple-negative breast cancer patients: a comprehensive analysis integrating scRNA-seq and... by Yulin Shi, Yang Yu, Jiahan Zhao, Linan Huang, Qingyang Wang, Qi Sun, Lijuan Liu, Changgang Sun

“…Pseudotime analysis confirmed that CD8+ Tex mainly clustered at the end of the differentiation pathways, making them a critical subset in TNBC progression. By analyzing the TCGA cohort, ten CD8+ Tex-related DEGs were identified as significantly correlated with overall survival (OS) in TNBC patients, and a prognostic model containing four biomarkers (GBP1, CTSD, ABHD14B, and HLA-A) was constructed. …”
Get full text

Development of a comprehensive sustainability index for extractive and mining companies: Integrating the Sustainable Development Goals by Marta Fernández-Hernández, Pedro Mora, Marcelo F. Ortega, Juan Pous Cabello

“…The practical application of this index is critical, providing a step-by-step guide for extractive and mining companies to adopt and utilize the sustainability index, aiding in compliance with future regulations.The results of this study show that the system of SDGs, targets, aspects, and metrics is naturally weighted towards social issues. …”
Get full text

Alkali metal salt modulated visible photocatalytic degradation of tetracycline hydrochloride by g-C3N4: Degradation pathway, mechanism and toxicity assessment by Yujie Jiao, Sujin Lu, Ru Li, Qikai Liu, Yongxia Ma, Fei Fu, Yaqi Mao, Yang Liu

“…Achieving efficient degradation of tetracyclines in aqueous environments using visible light is therefore of critical importance. In this study, CaCl2-modified melamine precursors were employed to synthesize CaCNx with varied microstructures through molten salt-assisted calcination, enabling high-efficiency visible-light-driven degradation of tetracycline in water. …”
Get full text

Antimicrobial Susceptibility Testing for Colistin: Extended Application of Novel Quantitative and Morphologic Assay Using Scanning Electron Microscopy by Omar Zmerli, Sara Bellali, Gabriel Haddad, Rim Iwaza, Akiko Hisada, Erino Matsumoto, Yusuke Ominami, Didier Raoult, Jacques Bou Khalil

“…We provide an extended application of the proof of concept for the utilization of the SEM-AST assay for Colistin for a number of clinically relevant bacterial species, providing a rapid and reliable susceptibility profile for a critical antibiotic.…”
Get full text

Big data acquisition for underground infrastructure condition assessment by Chao Wang, Zhipeng Xiao, Yixian Wang, Fei Wang, Zili Li

“…The condition assessment of underground infrastructure (UI) is critical for maintaining the safety, functionality, and longevity of subsurface assets like tunnels and pipelines. …”
Get full text

The relationship between prenatal drought exposure and the diversity and composition of gut microbiome in pregnant women and neonates by Qingbo Fang, Tianlai Qiu, Fenglan Chen, Xuqi Tian, Zijun Feng, Yanan Cao, Jinbing Bai, Jing Huang, Yanqun Liu

“…The gut microbiome also plays a critical role in human health. However, no studies have explored the effect of drought on the human gut microbiome. …”
Get full text

Microbial community differentiation in vent chimneys of the Lost City Hydrothermal Field reflects habitat heterogeneity by Osama M. Alian, William J. Brazelton, Karmina A. Aquino, Katrina I. Twing, H. Lizethe Pendleton, Gretchen Früh-Green, Susan Q. Lang, Matthew O. Schrenk, Matthew O. Schrenk

“…The findings of this study underscore the need to more closely examine microbe-mineral interactions in natural environments, critically informing not just population-level distributions, but also the functional underpinnings of these extremophile microbial communities.…”
Get full text

Epidemiological drivers of transmissibility and severity of SARS-CoV-2 in England by Pablo N. Perez-Guzman, Edward Knock, Natsuko Imai, Thomas Rawson, Cosmo Nazzareno Santoni, Joana Alcada, Lilith K. Whittles, Divya Thekke Kanapram, Raphael Sonabend, Katy A. M. Gaythorpe, Wes Hinsley, Richard G. FitzJohn, Erik Volz, Robert Verity, Neil M. Ferguson, Anne Cori, Marc Baguelin

“…Long-term strategies for monitoring and maintaining effective immunity against SARS-CoV-2 are critical to inform the role of NPIs to effectively manage future variants with potentially higher intrinsic transmissibility and severe outcomes.…”
Get full text

Spatial Cognitive EEG Feature Extraction and Classification Based on MSSECNN and PCMI by Xianglong Wan, Yue Sun, Yiduo Yao, Wan Zuha Wan Hasan, Dong Wen

“…With the aging population rising, the decline in spatial cognitive ability has become a critical issue affecting the quality of life among the elderly. …”
Get full text