Aurora kinase A expression in pleomorphic adenoma, adenoid cystic carcinoma, and mucoepidermoid carcinoma of salivary glands: an immunohistochemical study by Razieh Zare, Leila Izadi, Mario Alberto Alarcón-Sánchez, Masumeh Taghva, Mohammad Ali Ranjbar

“…Abstract Background Aurora kinase A (AurkA) plays a vital role in mitosis and is therefore critical in tumors development and progression. There are a few studies on AurkA expression in salivary gland tumors. …”
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Revealing Elasmobranch Distributions in Turbid Coastal Waters: Insights From Environmental DNA and Particle Tracking by Nick Dunn, Sophie Ward, Joanna Barker, Jake Davies, Sarah Davies, Ben Wray, Peter Robins, Isabelle Apetroaie, Jake Williams, Kevin Hopkins, David Curnick

“…We detected 11 elasmobranch species, including the critically endangered angelshark (Squatina squatina) and tope (Galeorhinus galeus). …”
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Advanced Learning Technologies for Intelligent Transportation Systems: Prospects and Challenges by Ruhul Amin Khalil, Ziad Safelnasr, Naod Yemane, Mebruk Kedir, Atawulrahman Shafiqurrahman, NASIR SAEED

“…Besides, we identify several future challenges and research directions that can push the boundaries of ITS, including the critical aspects, including transfer learning, hybrid models, privacy and security, and ultra-reliable low-latency communication. …”
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Facilitating automated fact-checking: a machine learning based weighted ensemble technique for claim detection by Md. Rashadur Rahman, Rezaul Karim, Mohammad Shamsul Arefin, Pranab Kumar Dhar, Gahangir Hossain, Tetsuya Shimamura

“…This paper proposes a novel ensemble machine learning framework for the effective detection of claims in a low-resource language like Bangla, a critical initial step in the automated fact-checking process. …”
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Relationship between Family and Myopia: Based on the Jiangsu School Student Myopia Study by Xiyan Zhang, Wenyi Yang, Jie Yang, Wei Du, Yao Xiang, Xin Wang, Chao Huang, Yan Wang, Fengyun Zhang

“…Therefore, previous interventions would still work, and then the most critical challenge would be to ensure that left-behind children completed more schooling.…”
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Multi-objective optimization of SUS430C steel turning process using hybrid machine learning and evolutionary algorithm approach by Nguyen Van-Canh, Nguyen Anh-Thang, Pham Ngoc-Linh, Nguyen Thuy-Duong

“…A hybrid approach combining Extreme Gradient Boosting (XGBoost) and Non-dominated Sorting Genetic Algorithm-II (NSGA-II) was employed to optimize three critical machining objectives: surface roughness (Ra), material removal rate (MRR), and tool wear (Vb). …”
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Therapeutic potential and mechanisms of umbilical cord mesenchymal stem cells differentiating into tendon cells and promotion of rotator cuff tendon-bone healing by Youliang Shen, Yuelei Wang, Yidan Xu, Jie Wang, Chuqiang Yin, Zengshuai Han, Feng Shen, Ting Wang

“…This study confirmed the potential of UCMSCs in tendon injury repair, especially the critical role of Hes1 in promoting UCMSCs differentiation and rotator cuff tendon-bone healing, which provides a theoretical basis and experimental rationale for the development of new cellular therapeutic strategies.…”
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Hypoxia Inducible Factor-1α Regulates the Migration of Bone Marrow Mesenchymal Stem Cells via Integrin α4 by Jong Ho Choi, Yun Bin Lee, Jieun Jung, Seong Gyu Hwang, IL-Hoan Oh, Gi Jin Kim

“…Although hypoxic environments have been known to regulate the migratory ability of bone marrow-derived mesenchymal stem cells (BM-MSCs), which is a critical factor for maximizing the therapeutic effect, the underlying mechanisms remain unclear. …”
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Genome-Wide Association Analysis of Boar Semen Traits Based on Computer-Assisted Semen Analysis and Flow Cytometry by Xiyan Yang, Jingkun Nie, Yaxuan Zhang, Suqing Wang, Xiaoping Zhu, Zhili Li, Yunxiang Zhao, Xiuguo Shang

“…Semen quality and persistence are critical for evaluating the usability of individual boars in AI, a standard practice in pig breeding. …”
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Humanising nanotoxicology: replacement of animal-derived products in the application of integrated approaches to testing and assessment of nanomaterial inhalation hazard by Roma Fraser, Keira Campbell, Pawel Pokorski, Eve MacKinnon, Katie McAllister, Karla B. Neves, Fiona Murphy

“…This has prompted the design of Novel Approach Methods (NAMs) to streamline risk assessment and predict human hazards without relying on animal testing. A critical aspect of advancing NAMs is the urgent need to replace animal-derived products in assay protocols. …”
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Graphene-metal sulfide composite based gas sensors for environmental sustainability: A review by Deepak Balram, Kuang-Yow Lian, Neethu Sebastian, Vineet Kumar, Virendra Kumar Yadav, Ashish Patel, Kulvinder Singh

“…In this modern era, maintaining a sustainable environment is pivotal and hence, a detailed review on gas sensors for quantification of toxic environmental pollutants is critical. In this paper, an extensive review on advancements in gas sensors developed using graphene-metal sulfide composites is discussed. …”
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Integrated AutoML-based framework for optimizing shale gas production: A case study of the Fuling shale gas field by Tianrui Ye, Jin Meng, Yitian Xiao, Yaqiu Lu, Aiwei Zheng, Bang Liang

“…This innovative framework addresses critical limitations often encountered in applying machine learning (ML) to shale gas production: the challenge of achieving sufficient model accuracy with limited samples, the multidisciplinary expertise required for developing robust ML models, and the need for interpretability in “black-box” models. …”
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Barriers and facilitators for healthcare access among immigrants in Japan: a mixed methods systematic review and meta-synthesisResearch in context by Yu Par Khin, Floret Maame Owusu, Nobutoshi Nawa, Pamela J. Surkan, Takeo Fujiwara

“…Interpretation: Findings highlight the critical importance of a multidimensional approach to support immigrants in Japan, ranging from improving healthcare information access to creating immigrant-friendly health systems. …”
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RailPC: A large‐scale railway point cloud semantic segmentation dataset by Tengping Jiang, Shiwei Li, Qinyu Zhang, Guangshuai Wang, Zequn Zhang, Fankun Zeng, Peng An, Xin Jin, Shan Liu, Yongjun Wang

“…Based on our findings, we establish some critical challenges towards railway‐scale point cloud semantic segmentation. …”
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Single-cell transcriptomics identify a novel macrophage population associated with bone invasion in pituitary neuroendocrine tumors by Xinzhi Wu, Xueshuai Han, Haibo Zhu, Mingxuan Li, Lei Gong, Sicheng Jing, Weiyan Xie, Zhaoqi Liu, Chuzhong Li, Yazhuo Zhang

“…Conclusions Our study elucidates the tumor microenvironment changes in bone invasion and identifies the critical role of TNF-α+ TAMs in promoting bone invasion of PitNETs, laying a foundation for developing new molecular markers or therapeutic agents targeting BI PitNETs.…”
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Experimental Study on the Creep Behavior of Red Sandstone under Low Temperatures by Yongjun Song, Leitao Zhang, Huimin Yang, Jianxi Ren, Yongxin Che

“…In addition, a decrease in temperature exponentially attenuates the total creep and viscoplastic strains of the rocks. 0°C is a critical point for the reduction of the total creep and viscoplastic strains of the rocks. …”
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Bayesian inverse analysis with field observation for slope failure mechanism and reliability assessment under rainfall accounting for nonstationary characteristics of soil properti... by Xian Liu, Shui-Hua Jiang, Jiawei Xie, Xueyou Li

“…The probabilities of slope failure and distributions of critical slip surface for various rainfall durations are then evaluated within a Monte-Carlo simulation framework. …”
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Hyperthermia and targeting heat shock proteins: innovative approaches for neurodegenerative disorders and Long COVID by David M. Smadja, David M. Smadja, M. Marc Abreu, M. Marc Abreu

“…Neurodegenerative diseases (NDs) and Long COVID represent critical and growing global health challenges, characterized by complex pathophysiological mechanisms including neuronal deterioration, protein misfolding, and persistent neuroinflammation. …”
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A Review of Agricultural Film Mapping: Current Status, Challenges, and Future Directions by Mengmeng Zhang, Jinwei Dong, Quansheng Ge, Hasituya, Pengyu Hao

“…Accurate and timely agricultural film maps are critical for supporting strategic agricultural planning and predicting environmental impacts. …”
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Inflation Pressure in Side Branch during Modified Jailed Balloon Technique Does Not Affect Side Branch Outcomes by Tetsuya Nomura, Naotoshi Wada, Issei Ota, Satoshi Tasaka, Kenshi Ono, Yu Sakaue

“…We speculate that lesion characteristics rather than the PCI procedural factors may be critical determinants to cause SB compromise.…”
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