Computational identification and experimental validation of novel Saccharum officinarum microRNAs along with their targets through RT-PCR approach by Abdul Baqi, Samiullah, Jadoon Khan, Asma Sadiq, Yousaf Khan, Shahid Ali, Syed Nadeem ul Hassan Mohani, Naqeebullah Khan, Tawaf Ali Shah, Khalid S. Almaary, Youssouf Ali Younous, Mohammed Bourhia

“…MicroRNAs (miRNAs) play critical regulatory roles in enhancing yield and providing protection against various stressors. …”
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Biosolids Effects in Chihuahuan Desert Rangelands: A Ten-Year Study by David B. Wester, Ronald E. Sosebee, Richard E. Zartman, Ernest B. Fish, J. Carlos Villalobos, Ricardo Mata-Gonzalez, Pedro Jurado, Corey A. Moffet

“…Topical application is critical to avoid soil and vegetation disturbance. …”
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Advancing Alzheimer's Therapy: Computational strategies and treatment innovations by Jibon Kumar Paul, Abbeha Malik, Mahir Azmal, Tooba Gulzar, Muhammad Talal Rahim Afghan, Omar Faruk Talukder, Samar Shahzadi, Ajit Ghosh

“…Our findings underscore the critical role of computational models in elucidating disease mechanisms, identifying therapeutic targets, and expediting drug discovery. …”
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Availability, accessibility and activation of mental health services among university students in Africa: a protocol of a mixed-methods systematic review with meta-analysis and met... by Hesborn Wao, Melvin A Wao, Ian Muriithi, Paul Seraii, Jackline Syonguvi

“…For cross-sectional studies, we will use the Joanna Briggs Institute Checklist for Analytical Cross Sectional Studies whereas qualitative or mixed-methods studies will be assessed using the Critical Appraisal Skills Programme. OR, risk ratio or mean difference with 95% CI will be considered as the effect size. …”
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Social Justice Work in the University: Understanding Student and Staff Perceptions and Aspirations for Decolonising the Curriculum from a University-Wide Survey by Kyra Araneta, Kelsea Costin, Jennifer Fraser, Fatima Maatwk, Özge Süvari, Esra Tahir

“…This study aims to enrich the discourse on social justice work in higher education by offering a critical lens on decolonial efforts and highlighting opportunities for collective action to rethink knowledge production and pedagogical practices. …”
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Liquid biopsy approaches to capture tumor evolution and clinical outcomes during cancer immunotherapy by Susan Scott, Mark Sausen, Valsamo Anagnostou, Jennifer Jackson, Vincent Lam, Joseph C Murray, Lavanya Sivapalan, Jenna Vanliere Canzoniero, Blair Landon, Benjamin P. Levy

“…The clinical translation of liquid biopsies is propelled by the increasing number of ctDNA-directed interventional clinical trials in the immuno-oncology space, signifying a critical step towards implementation of liquid biopsies in precision immuno-oncology.…”
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Ozone oxidative preconditioning: a protection against cellular damage by free radicals by O. S. León, S. Menéndez, N. Merino, R. Castillo, S. Sam, L. Pérez, E. Cruz, V. Bocci

“…Six groups of rats were classified as follows: (1) negative control, using intraperitoneal sunflower oil; (2) positive control using carbon tetrachloride (CCl4) as an oxidative challenge; (3) oxygen-ozone, pretreatment via rectal insufflation (15 sessions ) and after it, CCl4; (4) oxygen, as group 3 but using oxygen only; (5) control oxygen-ozone, as group 3, but without CCl4 ; group (6) control oxygen, as group 5, but using oxygen only. We have evaluated critical biochemical parameters such as levels of transaminase , cholinesterase , super - oxide dismutase, catalase , phospholipase A, calcium dependent ATPase, reduced glutathione , glucose 6 phosphate dehydrogenase and lipid peroxidation. …”
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Optimization of Well Patterns in Offshore Low-Permeability Thin Interbedded Reservoirs: A Numerical Simulation Study in the Bozhong Oilfield, China by Guangai Wu, Yingwen Ma, Yanfeng Cao, Anshun Zhang, Wei Liu, Jinghe Wang, Xinyi Yang

“…The findings provide critical insights into optimizing well patterns and fracture network designs for offshore low-permeability thin interbedded reservoirs.…”
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The effect of NLRP3 inflammasome on cardiovascular prognosis in patients with acute coronary syndrome by De-Gang Mo, Ming-Ting Liang, Li Xu, Tai Li, Qian-Feng Han, Chen Chen, Heng-Chen Yao

“…Abstract The NOD‑like receptor protein domain associated protein 3 (NLRP3) inflammasome is critical in inflammatory responses and may be a valuable prognostic biomarker in acute coronary syndrome (ACS). …”
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Topography of Genetic Loci in Tissue Samples: Towards New Diagnostic Tool Using Interphase FISH and High-Resolution Image Analysis Techniques by I. Koutná, S. Kozubek, J. Žaloudík, M. Kozubek, E. Lukášová, P. A. Matula, E. Bártová, M. Skalníková, A. Cafourková, P. Jirsová

“…In order to validate high‐resolution cytometry for oncology, further investigations should include more precise parameters reflecting the state of chromatin in the neighbourhood of critical oncogenes or tumour suppresser genes.…”
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Immune cell profiles and predictive modeling in osteoporotic vertebral fractures using XGBoost machine learning algorithms by Yi-Chou Chen, Hui-Chen Su, Shih-Ming Huang, Ching-Hsiao Yu, Jen-Huei Chang, Yi-Lin Chiu

“…These findings underscore the critical role of immune cells in the pathogenesis of osteoporotic fractures and highlight the potential of XGBoost in identifying key biomarkers and therapeutic targets for mitigating fracture risk in osteoporotic patients.…”
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Bronchotracheal Stenting Management by Rigid Bronchoscopy under Extracorporeal Membrane Oxygenation (ECMO) Support: 10 Years of Experience in a Tertiary Center by Sabrina Meyer, Anne-Sophie Dincq, Lionel Pirard, Sebahat Ocak, Jean-Paul D’Odémont, Philippe Eucher, Benoît Rondelet, André Gruslin, Laurie Putz

“…Hence, a strategy for maintaining oxygenation and hemodynamic stability should be anticipated to avoid critical situations. Herein, we report the use of extracorporeal membrane oxygenation (ECMO) in bronchotracheal stenting management to secure oxygenation and facilitate interventions. …”
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Microbial Characteristics and Functions in Coffee Fermentation: A Review by Xiaojing Shen, Qi Wang, Hongsheng Wang, Guoqing Fang, Ying Li, Jilai Zhang, Kunyi Liu

“…The first stage of coffee production is obtaining green coffee beans through the primary process. Fermentation is critical in the primary process of coffee, which is often related to yeasts, bacteria, and filamentous fungi. …”
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A systematic review of Aspilia africana (Pers.) C.D. adams traditional medicinal uses, phytoconstituents, bioactivities, and toxicities by Roggers Gang, Denis Okello, Yeongjun Ban, Youngmin Kang

“…This study aimed to systematically and critically compile data on the traditional medicinal uses, phytochemistry, bioactivities, botanical descriptions, and toxicities of A. africana. …”
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Phosphorus Dynamics in Managed and Natural Soils: SEM-PLS Analysis of <i>Vaccinium</i>, Forest, and Grassland Ecosystems by Chun Lu, Soh Sugihara, Satoshi Noma, Haruo Tanaka, Ryosuke Tajima, Shingo Matsumoto, Dai Hirose, Xueyan Zhang, Ning Wang, Takuya Ban

“…These findings underscore the critical importance of prioritizing chemical property management over physical modifications to optimize nutrient cycling, preserve soil fertility, and reduce reliance on external phosphorus inputs in agricultural systems. …”
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The Possible Role of TLR2 in Chronic Hepatitis B Patients with Precore Mutation by Malihe Moradzadeh, Sirous Tayebi, Hossein Poustchi, Kourosh Sayehmiri, Parisa Shahnazari, Elnaz Naderi, Ghodratollah Montazeri, Ashraf Mohamadkhani

“…These findings showed the dominance of G1896A pre-core mutation of HBV variants in this community which was correlated with serum TLR2. Moreover TLR2 is critical for induction of inflammatory cytokines and therefore ALT elevation.…”
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Syngeneic natural killer cell therapy activates dendritic and T cells in metastatic lungs and effectively treats low-burden metastases by Shih-Wen Huang, Yein-Gei Lai, Hao-Ting Liao, Chin-Ling Chang, Ruo-Yu Ma, Yung-Hsiang Chen, Yae-Huei Liou, Zhen-Qi Wu, Yu-Chen Wu, Ko-Jiunn Liu, Yen-Tsung Huang, Jen-Lung Yang, Ming-Shen Dai, Nan-Shih Liao

“…The inverse correlation between NK activity and metastasis incidence supports a critical role for NK cells in human metastatic surveillance. …”
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Measurement of the temperature-dependent cross-plane thermal conductivity of the Li-ion battery pouch cell by Minjoo Kim, Dong-min Kim, Young-Beom Kim, Bong Jae Lee

“…This research provides a detailed framework for evaluating the cross-plane thermal conductivity of Li-ion batteries, offering critical insights into their thermal behavior at different temperatures and contributing to developing their improved thermal management strategies.…”
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Real‐Time Lactate Detection in A Dynamic Environment Using Micrsensing Needles by Yuan‐Sin Tang, Ting‐Wei Huang, Tung‐Lin Yang, Huei‐Ying Cheng, Yu‐Ting Cheng, Hsiao‐En Tsai, Yung‐Chieh Lo, Y. S. Chen

“…Utilizing inkjet‐printing technology, the sensor demonstrates enhanced sensitivity and a reduced limit of detection (LoD), addressing critical challenges in clinical applications like hemodialysis and patient monitoring in ICU. …”
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Spatial mismatch and congruence in the taxonomic, functional, and phylogenetic diversities of fish assemblages in China's water diversion lakes by Zhice Liang, Rodolphe Elie Gozlan, Chenyi Kuang, Jiashou Liu, Chuanbo Guo

“…The interplay of evolutionary, ecological, and anthropogenic processes is critical in shaping species distributions and biodiversity patterns. …”
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