Autoimmune pulmonary alveolar proteinosis developed during treatment for systemic sclerosis: a case report by Tomoki Kozono, Kentaro Tanaka, Tomoko Yagi, Kazuto Kamikawaji, Masaki Watanabe, Azusa Iwanaga, Minako Hamada, Yoshifusa Koreeda, Hiromasa Inoue, Ikkou Higashimoto

“…All physicians should be aware that the appropriate diagnosis of PAP and the measurement of serum anti-GM-CSF antibodies will critically affect patient outcomes.…”
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Construction of Multi-Scale Fusion Attention Unified Perceptual Parsing Networks for Semantic Segmentation of Mangrove Remote Sensing Images by Xin Wang, Yu Zhang, Wenquan Xu, Hanxi Wang, Jingye Cai, Qin Qin, Qin Wang, Jing Zeng

“…This study provides valuable tools and methods for monitoring and protecting mangrove ecosystems, contributing to the preservation of these critical coastal environments.…”
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Redefining NSP12 activity in SARS-CoV-2 and its regulation by NSP8 and NSP7 by Deepa Singh, Tushar Kushwaha, Rajkumar Kulandaisamy, Vikas Kumar, Kamal Baswal, Saras H. Tiwari, Arkadyuti Ghorai, Manoj Kumar, Saroj Kumar, Soumya De, Aparoy Polamarasetty, Deepak Sehgal, Madhumohan R. Katika, Suresh Gadde, Marceline Côté, Sarala R. Kayampeta, Mohan Babu Appaiahgari, Krishna K. Inampudi

“…RdRp is a critical component of an RNA virus life cycle. Among coronaviruses, NSP12, along with one copy of NSP7 and two copies of NSP8, forms the RdRp holoenzyme and exhibits polymerase activity. …”
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Effects of a Novel Glucokinase Activator, HMS5552, on Glucose Metabolism in a Rat Model of Type 2 Diabetes Mellitus by Ping Wang, Huili Liu, Li Chen, Yingli Duan, Qunli Chen, Shoumin Xi

“…Glucokinase (GK) plays a critical role in the control of whole-body glucose homeostasis. …”
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Human Placenta-Derived Mesenchymal Stem Cells Reduce Mortality and Hematoma Size in a Rat Intracerebral Hemorrhage Model in an Acute Phase by Bo Young Choi, Ok Joon Kim, Sae-Hong Min, Jeong Hyun Jeong, Sang Won Suh, Tae Nyoung Chung

“…Intracerebral hemorrhage (ICH) is a critical disease, highly associated with mortality and morbidity. …”
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DLBWE-Cys: a deep-learning-based tool for identifying cysteine S-carboxyethylation sites using binary-weight encoding by Zhengtao Luo, Zhengtao Luo, Zhengtao Luo, Qingyong Wang, Qingyong Wang, Qingyong Wang, Yingchun Xia, Yingchun Xia, Yingchun Xia, Xiaolei Zhu, Xiaolei Zhu, Xiaolei Zhu, Shuai Yang, Shuai Yang, Shuai Yang, Zhaochun Xu, Zhaochun Xu, Lichuan Gu, Lichuan Gu, Lichuan Gu

“…Cysteine S-carboxyethylation, a novel post-translational modification (PTM), plays a critical role in the pathogenesis of autoimmune diseases, particularly ankylosing spondylitis. …”
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2-O-β-D-Glucopyranosyl-L-ascorbic acid, an ascorbic acid derivative isolated from the fruits of Lycium barbarum L., ameliorates high fructose-induced neuroinflammation in mice: inv... by Wei Dong, Yujia Peng, Guijie Chen, Zhiyong Xie, Weiqi Xu, Wangting Zhou, Jia Mi, Lu Lu, Yi Sun, Xiaoxiong Zeng, Youlong Cao, Yamei Yan

“…Neuroinflammation and cognitive impairment, two critical pathological characteristics of Alzheimer’s disease, have been closely associated with microbial alteration via the gut-brain axis. …”
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Classifications of haemodialysis vascular access stenosis: a scoping review by Petr Waldauf, Michael Corr, Stephen O’neill, Katerina Lawrie, Jan Malik, Libor Janousek, Stepan Maly, Jaroslav Chlupac

“…Four vascular surgeons assessed the included classifications using a modified Buchbinder’s critical appraisal tool to evaluate quality.Results From 4771 screened papers, 59 full-text papers were retrieved and 24 articles contained classifications. …”
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Application of international energy efficiency standards for energy auditing in a University buildings by V. Shcherbak, L. Ganushchak-Yefimenko, O. Nifatova, P. Dudko, N. Savchuk, I. Solonenchuk

“…Over the last 10 years energy consumption in Ukrainian higher education institutions against the world best practice exceed by 30-40%. This triggers a critical need to building an integrative approach to energy saving and energy efficiency management. …”
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Gate-to-gate life cycle assessment of lithium-ion battery recycling pre-treatment by Anna Pražanová, Michael Fridrich, Jan Weinzettel, Vaclav Knap

“…Recycling spent lithium-ion batteries (LIBs) is critical for enhancing environmental sustainability and resource conservation; however, the environmental and energy impacts of LIB recycling are not yet comprehensively understood due to the diverse applications of LIB cells and the variability in recycling technologies. …”
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A Review on Face Mask Recognition by Jiaonan Zhang, Dong An, Yiwen Zhang, Xiaoyan Wang, Xinyue Wang, Qiang Wang, Zhongqi Pan, Yang Yue

“…This review offers a comprehensive and in-depth analysis of face mask detection and recognition technologies, emphasizing their critical role in both public health and technological advancements. …”
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Bacterial Quality and Molecular Detection of Food Poisoning Virulence Genes Isolated from Nasser Lake Fish, Aswan, Egypt by Nady Khairy Elbarbary, Mohamed K. Dandrawy, Ghada Hadad, Maha Abdelhaseib, Amna A. A. Osman, Rawaf Alenazy, Ibrahim Elbagory, Neveen M. Abdelmotilib, Fagelnour Elnoamany, Ghada A. Ibrahim, Reda A. Gomaa

“…The microbial analysis of fish is critical for ensuring overall health. Uncooked fish can serve as a conduit for transmitting several types of microbes; the current investigation sought to assess the bacterial levels in various kinds of fish from Nasser Lake, Aswan, Egypt, considered the chief source of potable water in Egypt. …”
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An Ultra-Wide Range D-Shaped Fiber SPR Sensor with a Nanostructure of Gold–MoS₂ and Sodium for the Simultaneous Measurement of Refractive Index and Temperature by Xinglian Lu, Xiantong Yu, Jun Zhou, Min Chang, Dunke Lu

“…Refractive index (RI) and temperature (T) are both critical environmental parameters for environmental monitoring, food production, and medical testing. …”
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Effect of microstructure and neutron irradiation defects on deuterium retention in SiC by Alex Leide, Weicheng Zhong, Isabel Fernandez-Victorio, Isabel Fernandez-Victorio, Duc Nguyen-Manh, Duc Nguyen-Manh, Takaaki Koyanagi

“…Retention of hydrogen isotopes is a critical concern for operating fusion reactors as retained tritium both activates components and removes scarce fuel from the fuel cycle. …”
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Molecular structures and adsorption of dyes on bismuth oxychloride surfaces using density functional theory and Monte Carlo dynamic simulation by Tadesse Lemma Wakjira, Abebe Belay Gemta, Kumneger Tadele, Gashaw Beyene Kassahun, Umer sherefedin, T. Gurumurthi, Tesfaye Feyisa

“…Quantum theory of atoms in molecules analysis shows three critical points (atom, bond and ring) were observed in each dye. …”
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Parametrization of the dying brain: A case report from ICU bed-side EEG monitoring by Sebastian Zinn, Srdjan Z. Dragovic, Jan A. Kloka, Laurent M. Willems, Sebastian Harder, Stephan Kratzer, Kai D. Zacharowski, Gerhard Schneider, Paul S. García, Matthias Kreuzer

“…Background: Cortical high-frequency activation immediately before death has been reported, raising questions about an enhanced conscious state at this critical time. Here, we analyzed an electroencephalogram (EEG) from a comatose patient during the dying process with a standard bedside monitor and spectral parameterization techniques. …”
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Post-traumatic arthritis: overview on pathogenic mechanisms and role of inflammation by Roberta Ramonda, Leonardo Punzi, Anna Scanu, Francesca Oliviero, Roberto Luisetto, Paola Galozzi, Marta Favero

“…The activation of inflammatory mechanisms during the PTA acute phase appears to play a critical role in the chronic disease onset. Human studies and experimental models have revealed that a series of inflammatory mediators are released in synovial fluid immediately after the joint trauma. …”
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Nε-carboxyethyl-lysin influences atherosclerotic plaque stability through ZKSCAN3 acetylation-regulated macrophage autophagy via the RAGE/LKB1/AMPK1/SIRT1 pathway by Zhongwei Liu, Jing Liu, Xiqiang Wang, Yong Zhang, Yanpeng Ma, Gongchang Guan, Ya Yuwen, Ni He, Hanxiu Liu, Xingfeng Yu, Sen Ma, Junkui Wang, Jin Zhang, Ling Zhu, Yulian Zhang

“…These findings highlight CEL’s critical role in promoting plaque instability in T2DM by impairing key molecular pathways that regulate autophagy, offering potential therapeutic targets for managing atherosclerosis in diabetic patients.…”
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Experimental investigation of CF8 stainless steel impeller quality using PLA-based fused deposition modeling-assisted investment casting by Margi Shah, Dhiren Patel, Sarang Pande, Mustufa Haider Abidi, Fahad Alasim

“…Dimensional accuracy and surface roughness, key indicators of quality, were evaluated at both the printing and casting stages. Critical dimensions such as outer and inner diameters, shroud and blade thicknesses, and total height were measured, along with surface roughness at the shroud and blade surfaces. …”
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Geochemical evolution and mechanisms controlling groundwater chemistry in the transboundary Komadugu–Yobe Basin, Lake Chad region: An integrated approach of chemometric analysis an... by Abdulrahman Shuaibu, Robert M. Kalin, Vernon Phoenix, Ibrahim Mohammed Lawal

“…Study region: The study is conducted in the transboundary Komadugu–Yobe Basin, Lake Chad region, a critical groundwater resource shared across national boundaries of Nigeria and Niger Republic. …”
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