Bionic nanovesicles sequentially treat flaps with different durations of ischemia by thrombolysis and prevention of ischemia-reperfusion injury by Linzhong Yang, Yuanchen Liu, Cheng Tao, Zichen Cao, Shilin Guo, Zheng Wei, Yanyi Wang, Tao Liu, Lin Chen, Ke Xiong, Xingyu Luo, Jianchuan Ran, Wei Han

“…Flap transplantation is a critical part of the recovery process for patients who have undergone tumor resection. …”
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A socioeconomic disadvantage index for informing policy, systems, and environmental change interventions for senior nutrition programs by Shadi Maleki, Cassandra M. Johnson, Francis A. Méndez Mediavilla, Ramalingam Shanmugam, Lesli Biediger-Friedman

“…Identifying socioeconomic disparities within a local area is critical for tailoring policy solutions to older adult populations. …”
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Study on the influence of working environment on the insulation of fuel cell by Ji Pu, Qianya Xie, Kang Li, Jun Li, Mengmeng Zhang, Chen Ge, Lichang Zhang

“…These research results are critical for advancing commercial applications.…”
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The contribution of leaders' and managers' attributes, values, principles, and behaviours to the sustainable implementation of Lean in healthcare: A realist review protocol [versio... by Seán Paul Teeling, Anne Marie Keown, Martin McNamara

“…By exploring how leadership attributes, values, principles and behaviours shape outcomes for diverse stakeholders, the review aims to provide critical insights into the dynamics driving the success of Lean in healthcare. …”
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MEST Regulates the Stemness of Human Periodontal Ligament Stem Cells by Daigaku Hasegawa, Kana Hasegawa, Hiroshi Kaneko, Shinichiro Yoshida, Hiromi Mitarai, Mai Arima, Atsushi Tomokiyo, Sayuri Hamano, Hideki Sugii, Naohisa Wada, Tamotsu Kiyoshima, Hidefumi Maeda

“…These results suggest that MEST plays a critical role in the maintenance of stemness in PDLSCs and converts PDL cells into PDLSC-like cells. …”
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Water Quality Variations in the Lower Yangtze River Based on GA-RF Model From GF-1, Landsat-8, and Sentinel-2 Images by Wentao Hu, Shuanggen Jin, Yuanyuan Zhang

“…Total phosphorus (TP) and total nitrogen (TN) are critical water quality indicators in the Yangtze River and remote sensing techniques can inverse these parameters. …”
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QUANTIFICATION CONTRASTS OF LEXICAL MICROSYSTEMS WITH SYNONYMS SЪVEDETELЬ – POSLUKHЪ (A WITNESS) AND THEIR DERIVATIVES IN THE OLD EAST SLAVIC WRITTEN SOURCES (BASED ON MANUSCRIPT... by Oleg F. Zholobov

“…In the church written tradition, the ratio of lexemes in the corresponding lexical series is expressed by contrasting quantitative formulas that reflect the text-critical history, genre-stylistic nature, and discursive dominants of the texts. …”
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Variation and simulation of tomato transpiration in a greenhouse under different ventilation modes by Jiankun Ge, Sen Wang, Xuewen Gong, Yuhao Zhu, Zihui Yu, Yanbin Li

“…Greenhouse ventilation is a critical factor in regulating internal microclimates, ensuring optimal crop growth, and improving water use efficiency in facility agriculture. …”
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Genome-wide identification of the bHLH gene family in Scutellaria baicalensis and their relationship with baicalin biosynthesis under drought stress by Yingxin Sun, Beier Wang, Lichao Zhang, Xiaohan Zheng, Peng Xu, Meng Zhang, Meiguang Han, Peng Di, Mei Han, Lin Cheng, Limin Yang

“…The bHLH gene family plays a critical role in regulating internal responses in plants. …”
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Automatic Segmentation of Abdominal Aortic Aneurysm From Computed Tomography Angiography Using a Patch-Based Dilated UNet Model by Merjulah Roby, Juan C. Restrepo, Haehwan Park, Satish C. Muluk, Mark K. Eskandari, Seungik Baek, Ender A. Finol

“…This advancement is essential in addressing the critical need for clinical accuracy in medical image segmentation. …”
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Towards a net-zero healthcare system in Kenya: Stakeholder perspectives on opportunities, challenges and priorities by Iris Martine Blom, Melvine Anyango Otieno, Susannah Mayhew, Neil Spicer, Andy Haines, Sarah Whitmee

“…Results: Stakeholders identified and validated 14 process components crucial for this transformation, ranging from leadership and financing to behavioral change and monitoring. Critical barriers, such as infrastructure limitations, competing health priorities, financial constraints, and gaps in strategy coordination, were highlighted. …”
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First‐in‐human orbital tumor surgery guided by near‐infrared II window fluorescence imaging: A feasibility study by Zeyu Zhang, Lishuang Guo, Lan Yao, Yueyue Li, Yan Hei, Qi Wang, Xiaoyi Wang, Rui Ma, Xinji Yang, Zhenhua Hu, Wei Wu

“…Abstract Precise resection of orbital tumors is a critically important but elusive issue. Fluorescence imaging in the near‐infrared II window (NIR‐II) holds the potential to provide the surgeons with real‐time identification for orbital tumors. …”
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Cardiovascular Disease Detection through Innovative Imbalanced Learning and AUC Optimization by Karthikeyan Palanisamy, Krishnaveni Krishnasamy, Praba Venkadasamy

“…The performance of this model was rigorously evaluated using comprehensive data from a medical survey conducted in 2012, which included an extensive cohort of 26,002 athletes. Critical parameters such as height, weight, age, gender, blood pressure, and resting heart rate were meticulously documented. …”
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The Impact of Space Radiation on Brains of Future Martian and Lunar Explorers by Yuncong Li, Jingnan Guo, Salman Khaksarighiri, Mikhail Igorevich Dobynde, Jian Zhang, Bailiang Liu, Robert F. Wimmer‐Schweingruber

“…Space radiation exposure from energetic particles of Solar Energetic Particles (SEPs) and Galactic Cosmic Rays (GCRs) can adversely impact the Central Nervous System (CNS) by inducing acute (i.e., mission critical) and chronic (i.e., post‐mission) effects, respectively. …”
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Dynamic analysis of growth characteristics, secondary metabolites accumulation, and an in-depth understanding of anthraquinones biosynthesis in Rubia cordifolia Linn. by Conglong Lian, Conglong Lian, Conglong Lian, Xiuyu Liu, Xiuyu Liu, Kaihua Guo, Kaihua Guo, Hao Yang, Hao Yang, Jingfan Yang, Jingfan Yang, Jinxu Lan, Jinxu Lan, Suiqing Chen, Suiqing Chen, Suiqing Chen, Suiqing Chen

“…With the current depletion of natural resources of R. cordifolia, it is critical to conduct cultivation studies on the R. cordifolia. …”
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Optimizing Stroke Detection Using Evidential Networks and Uncertainty-Based Refinement by Faranak Akbarifar, Sean P. Dukelow, Albert Jin, Parvin Mousavi, Stephen H. Scott

“…The model’s ability to identify subtle motor deficits, even in TIA patients who show no observable symptoms on standard clinical exams, highlights its significant clinical utility. Detecting TIA is critical, as individuals who experience a TIA have a substantially higher risk of recurrent stroke. …”
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Evaluation of Coal Pore Connectivity Using N2 Sorption Isotherm and Spontaneous Imbibition Tests by Tong-qiang Xia, Jiao-fei He, Shi-xing Fan, Qiang-qiang Zhang, Zi-long Li, Dun-shuai Sun

“…Pore structure and connectivity of coal are critical factors in coal gas migration and production, which can be characterized by studying the kinetics of capillary imbibition behaviour within the pore spaces. …”
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Divergent Adsorption Regulation in Metal–Organic Frameworks for Highly Efficient CF4/C2F6 Separation by Guihong Xu, Tian Ke, Rongrong Fan, Kaiyuan Tan, Wenjun Zhang, Baogen Su, Zhiguo Zhang, Zongbi Bao, Qilong Ren, Qiwei Yang

“…Focusing this challenge on the critical task of purifying perfluorocarbons in electronics industry, a divergent regulation strategy is reported that significantly improves the separation efficiency of low‐concentration hexafluoroethane (C2F6) from tetrafluoromethane (CF4). …”
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The impact of digital transformation on sustainability: a case of the Iranian telecom industry by Jamal Aghayari, Changiz Valmohammadi, Mahmood Alborzi

“…Therefore, through an in-depth review of the relevant literature, critical factors and their indicators were determined, and based on the proposed conceptual model, six hypotheses were developed. …”
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Adjuvanted subunit intranasal vaccine reduces SARS-CoV-2 onward transmission in hamsters by Yongjun Sui, Swagata Kar, Bhavna Chawla, Tanya Hoang, YuanKai Yu, Shannon M. Wallace, Hanne Andersen, Jay A. Berzofsky

“…IntroductionMost COVID-19 vaccine trials have focused on recipient protection, not protection of their contacts, a critical need. As a subunit intranasal COVID-19 vaccine reduced nasopharyngeal virus more than did an intramuscular (IM) vaccine, we hypothesized that this vaccine might reduce onward transmission to others.MethodsWe vaccinated hamsters with either the IM-administrated licensed mRNA vaccine twice or one dose of mRNA IM followed by adjuvanted subunit intranasal vaccine. 24 hours after SARS-CoV-2 challenge, these animals were housed with naïve recipients in a contactless chamber that allows airborne transmission.ResultsOnward airborne transmission was profoundly blocked: the donor and recipients of the intranasal vaccine-boosted group had lower oral and lung viral loads (VL), which correlated with mucosal ACE2 inhibition activity. …”
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