The Emerging Roles of the Calcineurin-Nuclear Factor of Activated T-Lymphocytes Pathway in Nervous System Functions and Diseases by Maulilio John Kipanyula, Wahabu Hamisi Kimaro, Paul F. Seke Etet

“…Calcineurin/NFAT signaling is known for its critical roles in the developing and adult nervous system. …”
Get full text

Ainu Representation in the World of Japanese Comics: Shumari and Golden Kamuy Take on the Ruling Narratives of Hokkaidō History by Zsófia Keller

“…Consequently, Hokkaidō is often still perceived as a natural frontier developed by settlers for the benefit of the Japanese nation, while the Ainu continue to be stereotyped as a dying race. By critically engaging with these prevailing narratives, Tezuka and Noda elevate their work to what Pierre Nora calls places of memory. …”
Get full text

Developmental inequity and the impact of pesticide exposure on gut and brain health in developing nations – a Brazilian perspective by Jessica Gama, Bianca Cruz Neves, Antonio Pereira

“…Pesticide exposure, which may begin prenatally through maternal pathways and continue postnatally, has the potential to disrupt this microbiome and affect critical neurodevelopmental processes, likely altering lifelong health outcomes. …”
Get full text

Evaluation of Laundry Units in Teaching Hospitals of Tehran University of Medical Sciences and Recommendations for Performance Enhancement by Mohammad Amin Zar Foroush, Zeinab Partovi Shayan, Ghasem Rajabi Vasakolaei

“…Background and purpose: The laundry unit is one of the most critical support services in a hospital. Optimizing processes and implementing effective management strategies in this unit can significantly impact cost management. …”
Get full text

The Growing Mpox Infections by Clade I Variant in African Countries Is a Public Health Emergency of International Concern: A Narrative Review by Taslima Jamal Urmi, Md. Rabiul Islam

“…Conclusion The emergence of the new clade of mpox represents a critical public health challenge that necessitates immediate and coordinated global response efforts. …”
Get full text

A study of the impact of urban business credit environment on environmental pollution. by Jing Wu, Qing Guo

“…Environmental pollution has become a global concern, so it is critical to find out the elements that influence it. …”
Get full text

Etoricoxib–NLC Mitigates Radiation-Induced Ovarian Damage in Rats: Insights into Pro-Inflammatory Cytokines, Antioxidant Activity, and Hormonal Responses by Sahar Khateeb

“…Radiotherapy is a critical treatment for cancer but poses significant risks to ovarian tissue, particularly in young females, leading to premature ovarian failure (POF). …”
Get full text

Flexible Model Predictive Control for Bounded Gait Generation in Humanoid Robots by Tianbo Yang, Yuchuang Tong, Zhengtao Zhang

“…With advancements in bipedal locomotion for humanoid robots, a critical challenge lies in generating gaits that are bounded to ensure stable operation in complex environments. …”
Get full text

Exploring medical students’ intention to use of ChatGPT from a programming course: a grounded theory study in China by Chen Wang, Changqi Xiao, Xuejiao Zhang, Yingying Zhu, Xueqing Chen, Yilin Li, Huiying Qi

“…Conclusions Based on the analysis of influencing factors, strategies and suggestions such as preventing risks and focusing on ethical education, cultivating critical thinking and establishing a case library, and personalized teaching to enhance core literacy in programming are proposed.…”
Get full text

Peer Social Support and Career Decision-Making in Adolescents from Broken Homes: A Career Counseling Perspective by Maria Jessica Gultom, Doddy Hendro Wibowo

“…Most participants reported receiving high levels of peer support and low levels of career decision-making difficulties, demonstrating the critical role that peer networks play in providing both emotional and informational support. …”
Get full text

Determinant domain in prognosis evaluation of the septic patient in the intensive care unit. by Alexis Díaz Mesa, Rubén Bembibre Taboada, Alexis Suárez del Villar Labastida, Dagmaris Losa Pérez

“…<strong>Background:</strong> Sepsis is the most frequent cause of death in critical ill patient. The necessity to have with evolutionary and predictable markers for medical routines is a tangible fact. …”
Get full text

Spatially Varying Relation between Built Environment and Station-Level Subway Passenger-Distance by Hongtai Yang, Zhihao Zhao, Chaozhe Jiang, Yi Wen, Malik Muneeb Abid

“…While ridership is an important indicator for evaluating subway demand, passenger-distance is another critical indicator that incorporates distance into demand evaluation, which has not yet been fully explored. …”
Get full text

Precision optimization of reactive squeezing flow in stratified fluids: A response surface exploration by Anum Shafiq, Tabassum Naz Sindhu, Muhammad Ahmad Iqbal

“…The non-linear governing system is solved numerically using the Runge–Kutta fourth-order method (RK-4) combined with the shooting technique. Critical parameter variations are illustrated through graphical representations, highlighting their impact on the relevant fields. …”
Get full text

Territorialidade e ancestralidade: formação e reconhecimento da comunidade pescadora extrativista do Quilombo do Degredo, Brasil by Lorena Lins, Augusto Cesar Salomão Mozine

“…By February 2016, mining tailings carried by the wind had reached Degredo beach, further affecting the community. Drawing on critical political ecology, this article highlights how Degredo contends with agricultural and industrial exploitation projects while addressing long-standing socio-environmental conflicts. …”
Get full text

Aerobic-exercise training effects on immunological markers in individuals on highly active antiretroviral therapy in Uganda by Constance Adron Nakayiza Nsibambi, Mshilla Maghanga, Edward Ojuka, Mwebaze Nicholas

“…There is critical relevance in understanding the multidisciplinary management of HIV/AIDs among individuals obtaining health services in Uganda. …”
Get full text

Pengaruh Variasi Latihan Core Terhadap Kemampuan Balance dan Forehand Drive Atlet Putra by M. Wahyu Hidayah NST, David Siahaan

“…The analysis revealed a t-value of 16.813 for balance and 13.636 for forehand drive, both exceeding the critical t-value of 2.015. These findings indicate that core training variations positively influenced both balance and forehand drive performance in male athletes of the Unimed Tennis Community. …”
Get full text

TRIM25: A Global Player of Cell Death Pathways and Promising Target of Tumor-Sensitizing Therapies by Wolfgang Eberhardt, Usman Nasrullah, Josef Pfeilschifter

“…In addition to its originally described function in antiviral innate immune response, TRIM25 can play critical yet context-dependent roles in apoptotic- and non-apoptotic-regulated cell death pathways, including pyroposis, necroptosis, ferroptosis, and autophagy. …”
Get full text

Subjective assessment of sedentary behavior between theory and practice: Pilot study using the “Sedentary meter” by Ana Cikač, Kaja Teraž, Saša Pišot

“…The simple tool for accessing SB raised awareness of which specific type of SB accounts for the majority of participants' daily sedentary time. The self-critical acceptance of the &ldquo;poor results&rdquo; across all age groups shows the effectiveness of the initiative in raising awareness of SB issues.…”
Get full text

Gingival fibroblast suppress the osteogenesis process mediated by bone substitute materials via WNT/β-catenin signaling pathway in vitro and in vivo by Guanqi Liu, Jiahui Lin, Xiaoyan Chen, Runheng Liu

“…BackgroundThe regeneration of bone tissue is a critical challenge in oral and maxillofacial surgery, with the success of such procedures often depending on the ability to promote osteogenesis while managing the soft tissue environment. …”
Get full text

Wafer Defect Classification Algorithm With Label Embedding Using Contrastive Learning by Jeongjoon Hwang, Somi Ha, Dohyun Kim

“…Classifying wafer defects in the wafer manufacturing process is increasingly critical for ensuring high-quality production, optimizing processes, and reducing costs. …”
Get full text