Individualized drug therapy and survival prediction in ICU patients with acute kidney injury: construction and validation of a nomogram by Rui Yang, Xiaozhe Su, Ziqi Liu, Shuai Shao, Yinhuai Wang, Hao Su, Haiqing He

“…Hence, it is necessary to investigate the potential of medication history as a predictor of survival outcomes among AKI patients in the intensive care unit (ICU). Methods Critically ill AKI patients were sourced from the MIMIC-IV database. …”
Get full text

Seminal plasma protein profiles based on molecular weight as biomarkers of sperm fertility in horned and polled Bali bulls by Rasyidah Mappanganro, Herry Sonjaya, Sudirman Baco, Hasbi Hasbi, Sri Gustina

“…Background and Aim: Seminal plasma proteins (SPPs) significantly influence sperm quality, playing a critical role in fertility. This study aims to investigate the molecular weight (MW) profiles of SPPs in horned and polled Bali bulls and their correlation with sperm quality parameters. …”
Get full text

Automatic priority analysis of emergency response systems using internet of things (IoT) and machine learning (ML) by Abu S.M. Mohsin, Shadab H. Choudhury, Munyem Ahammad Muyeed

“…This innovative integration of IoT and ML has the potential to transform emergency response systems, optimizing resource allocation, reducing response times, and ultimately saving more lives in critical situations.…”
Get full text

Advantages of using T1-mapping in cardiac magnetic resonance imaging in patients with acromegaly by Alina A. Almaskhanova, Konstantin V. Melkozerov, Elena G. Przhiyalkovskaya, Natalia V. Tarbaeva, Anastasya Y. Korneluk, Raisa S. Kosharnaia, Victor Y. Kalashnikov, Zhanna E. Belaya, Galina A. Mel'nichenko, Natalia G. Mokrysheva

“…The duration of the disease was found to be critical for myocardial remodeling (p=0.006). Compliance criteria for the T1-mapping technique were determined, with reduced T1-mapping values observed in 85.2% of cases. …”
Get full text

Correlation of Computed Tomography Angiography and Fractional Flow Reserve Features with Symptoms in Patients with Right Coronary Artery Originating from the Left Coronary Sinus by Liang MAO, Xiaoqiang WANG, Xiaolong LIU, Ning ZHAI, Yueqin CHEN

“…Changes in CT-FFR are related to cardiovascular symptoms; however, further research is needed to determine measurement methods and critical values.…”
Get full text

Enhancing palm precision agriculture: An approach based on deep learning and UAVs for efficient palm tree detection by Yosra Hajjaji, Wadii Boulila, Imed Riadh Farah, Anis Koubaa

“…The palm sector plays a critical role in achieving the Sustainable Development Goals (SDGs). …”
Get full text

Efficient adsorption of ofloxacin in a novel nanocomposite formed by nano-hexagonal boron nitride fused with zeolite imidazolite skeleton-8: Experimental and molecular dynamics sim... by Zefang Huang, Yuankai Hong, Yiqun Cui, Huiying Guo, Yan Long, Jinshao Ye

“…With the widespread application of antibiotics in the medical field, associated wastewater pollution has become a critical environmental issue, creating potential risks to ecosystems and public health. …”
Get full text

The multifaceted power of biochar: A review on its role in pollution control, sustainable agriculture, and circular economy by Amreen Bano, Mohd Kashif Aziz, Bablu Prasad, Rajesh Ravi, Maulin P. Shah, Pollyanna Vanessa Dos Santos Lins, Lucas Meili, Kumar Suranjit Prasad

“…It highlights the advantages, challenges, and diverse applications of biochar while critically examining current challenges and research gaps in its potential to mitigate greenhouse gas emissions, enhance soil carbon sequestration, and improve wastewater treatment processes.The potential of biochar to reduce greenhouse gas emissions and sequester carbon in soils, along with its applications in wastewater treatment, are thoroughly covered in this article. …”
Get full text

Insights from the single-cell level: lineage trajectory and somatic-germline interactions during spermatogenesis in dwarf surfclam Mulinia lateralis by Yajuan Li, Huilan Wei, Xiaoting Dai, Lijing Zhang, Liangjie Liu, Xiaomei Chen, Tian Liu, Ya Shu, Yaxin Yang, Shi Wang, Zhenmin Bao, Lingling Zhang

“…., MYC, SREBF1, SOXH) that may play a critical role in these cell types. Furthermore, our findings revealed that there is extensive bidirectional communication between the somatic cells and the germline cells, including the FGF and TGF-β signaling pathways, as well as other ligand-receptor pairs, such as NTN1-NEO1 and PLG-PLGRKT. …”
Get full text

Nonlinear relationship between hepatic steatosis index and reversion to normal glucose regulation in Chinese adults with prediabetes by Haiyong Zeng, Fei Yu, Haofei Hu, Yong Han, Ruixue Ye, Changchun Cao

“…Furthermore, a nonlinear relationship was identified between HSI levels and the reversion to NGR, with a critical threshold at an HSI value of 43.08. Below this threshold, a strong negative association was observed, markedly enhancing the probability of returning to normoglycemic status (HR = 0.91, 95% CI: 0.88–0.94, P < 0.0001). …”
Get full text

Increased TSPO alleviates neuropathic pain by preventing pyroptosis via the AMPK-PGC-1α pathway by Baolong Li, Kaiming Yu, Xiongyao Zhou, Jialu Sun, Le Qi, Weiye Li, Tuo Yang, Weizhen Li, Ningning Wang, Xiaosong Gu, Shusen Cui, Rangjuan Cao

“…Bioinformatics analysis revealed that pyroptosis and inflammatory responses induced by spared nerve injury (SNI) in the spinal dorsal horn play a critical role in the initiation and persistence of neuropathic pain. …”
Get full text

Exploring the Connectivity Between Education 4.0 and Classroom 4.0: Technologies, Student Perspectives, and Engagement in the Digital Era by Kapil Joshi, Rajesh Kumar, Salil Bharany, Dilip Kumar Jang Bahadur Saini, Rajiv Kumar, Ashraf Osman Ibrahim, Abdelzahir Abdelmaboud, Wamda Nagmeldin, Mohammad Awad Medani

“…In the future, it is critical to investigate and build creative instructional practices that effectively synergize with Classroom 4.0. …”
Get full text

Comprehensive Analysis of <i>blaCTX-M1</i> Gene Expression Alongside <i>iutA</i>, <i>csgA</i>, and <i>kpsMII</i> Virulence Genes in Septicemic <i>Escherichia coli</i> Using Real-Ti... by Mohsen Karbalaei, Mojgan Esmailpour, Valentyn Oksenych, Majid Eslami

“…Monitoring of these genes is critical for developing effective therapeutic strategies. …”
Get full text

Mindfulness-based retreat for mothers of paediatric heart transplant recipients: protocol for a pilot intervention study by Sara Ahola Kohut, Joanna Mitchell, Samantha J Anthony, Taylor Robertson, Heather Telfer, Mirna Seifert-Hansen

“…Given that a mother’s ability to successfully cope with the demands of her caregiving role may be predictive of positive familial psychosocial outcomes, it is critical that maternal coping is assessed and supported in paediatric healthcare. …”
Get full text

The Addis Declaration on Immunization: Assessing the Effectiveness and Efficiency of Immunization Service Delivery Systems in Africa as of the End of 2023 by Franck Mboussou, Charles Shey Wiysonge, Bridget Farham, Ado Bwaka, Sarah Wanyoike, Amos Petu, Sidy Ndiaye, Andre Bita Fouda, Johnson Muluh Ticha, Adidja Amani, Regis Obiang, Magaran Monzon Bagayoko, Benido Impouma

“…<b>Conclusions</b>: It is critical, as a follow up to this study, to document best practices from the seven countries that achieved the fourth ADI commitment. …”
Get full text

Absent in melanoma 2: a potent suppressor of retinal pigment epithelial-mesenchymal transition and experimental proliferative vitreoretinopathy by Yu Chen, Mingyuan Jiang, Liping Li, Shanshan Yang, Zuimeng Liu, Shiwen Lin, Wanxiao Wang, Jinyang Li, Feng Chen, Qiang Hou, Xiaoyin Ma, Ling Hou

“…Abstract Epithelial-to-mesenchymal transition (EMT) is a critical and complex process involved in normal embryonic development, tissue regeneration, and tumor progression. …”
Get full text

YOLOv8-LCNET: An Improved YOLOv8 Automatic Crater Detection Algorithm and Application in the Chang’e-6 Landing Area by Jing Nan, Yexin Wang, Kaichang Di, Bin Xie, Chenxu Zhao, Biao Wang, Shujuan Sun, Xiangjin Deng, Hong Zhang, Ruiqing Sheng

“…The analysis of this impact crater catalogue has provided critical support for landing site selection and characterization of the CE-6 mission and lays the foundation for future lunar geological studies.…”
Get full text

The Solar and Geomagnetic Storms in 2024 May: A Flash Data Report by Hisashi Hayakawa, Yusuke Ebihara, Alexander Mishev, Sergey Koldobskiy, Kanya Kusano, Sabrina Bechet, Seiji Yashiro, Kazumasa Iwai, Atsuki Shinbori, Kalevi Mursula, Fusa Miyake, Daikou Shiota, Marcos V. D. Silveira, Robert Stuart, Denny M. Oliveira, Sachiko Akiyama, Kouji Ohnishi, Vincent Ledvina, Yoshizumi Miyoshi

“…We compared naked-eye and camera auroral visibility, providing critical caveats on their difference. We also confirmed global disturbances of the storm-enhanced density of the ionosphere.…”
Get full text

External validation of AI-based scoring systems in the ICU: a systematic review and meta-analysis by Patrick Rockenschaub, Ela Marie Akay, Benjamin Gregory Carlisle, Adam Hilbert, Joshua Wendland, Falk Meyer-Eschenbach, Anatol-Fiete Näher, Dietmar Frey, Vince Istvan Madai

“…Thus, external validation is a critical – but frequently overlooked – step to establish the reliability of predicted risk scores to translate them into clinical practice. …”
Get full text

Development of a novel strategy for the quantification of ultra-trace impurity elements in high-purity magnesium using inductively coupled plasma tandem mass spectrometry by Liang Fu, Guangsheng Huang, Yaobo Hu, Xianhua Chen, Jingfeng Wang, Fusheng Pan

“…Impurities in high-purity magnesium affect material properties, which has become the most critical factor restricting its application. However, accurate analysis of multiple ultra-trace impurity elements in high-purity magnesium is extremely challenging. …”
Get full text