Enhancement of chemotherapy using oncolytic virotherapy: Mathematical and optimal control analysis by Joseph Malinzi, Rachid Ouifki, Amina Eladdadi, Delfim F. M. Torres, K. A. Jane White

“…The results from this sensitivity analysis indicate the existence of a critical dose of chemotherapy above which no further significant reduction in the tumour population can be observed. …”
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Optimization of photocatalytic degradation of Eriochrome Black T from aqueous solution using TiO2-biochar composite by Mohammednur Abdu, Solomon Tibebu, Saeideh Babaee, Abebe Worku, Titus A.M. Msagati, Jemal Fito Nure

“…Efficient dye removal methods are critical for preventing pollution and safeguarding ecosystems. …”
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Carbon finance for forest resilience in California by Micah Elias, Ethan Yackulic, Katharyn Duffy, Katharyn Duffy, Phil Saksa, Daniel L. Sanchez, Nicholas Pevzner, Spencer Plumb, Jillian Dyszynski, Carina Bracer

“…To maximize certainty of carbon benefits, landscape level treatments, DPBs, and ex-post carbon crediting will be critical. This study shows that carbon revenue from traditional markets or novel carbon contribution programs can help close the funding gap for forest restoration in California while underscoring the need for innovative conservation finance mechanisms to support ecosystem resilience and climate mitigation goals.…”
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Shifting vegetation phenology in protected areas: A response to climate change by Irina Ontel, Sorin Avram, Carmen Adriana Gheorghe, Mihaita Iulian Niculae, Ionuț Silviu Pascu, Steliana Rodino

“…This study comprehensively examined the impact of climate change on vegetation phenology within Romanian protected areas (PAs), focusing on critical phenological indicators such as the start of season (SOS), end of season (EOS), length of season (LOS), position of peak (POP), and photosynthetic metrics, including mean spring (MSP) and mean autumn (MAU). …”
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Development of a duplex real-time recombinase aided amplification assay for the simultaneous and rapid detection of PCV3 and PCV4 by Renjie Sun, Hanze Liu, Siqi Sun, Yating Wang, Ying Shan, Xiaoliang Li, Weihuan Fang, Yongle Yang, Ronghui Xie, Lingyan Zhao

“…A rapid and accurate method for detection of PCV3 and PCV4 is critical for controlling the transmission of associated disease. …”
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A Supervised Explainable Machine Learning Model for Perioperative Neurocognitive Disorder in Liver-Transplantation Patients and External Validation on the Medical Information Mart... by Zhendong Ding, Linan Zhang, Yihan Zhang, Jing Yang, Yuheng Luo, Mian Ge, Weifeng Yao, Ziqing Hei, Chaojin Chen

“…ObjectiveThis study used machine learning (ML) algorithms with an aim to extract critical predictors and develop an ML model to predict PND among LT recipients. …”
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Drone imagery dataset for early-season weed classification in maize and tomato cropsDIGITAL.CSIC by Gustavo A. Mesías-Ruiz, José M. Peña, Ana I. de Castro, José Dorado

“…Identifying weed species at early-growth stages is critical for precision agriculture. Accurate classification at the species-level enables targeted control measures, significantly reducing pesticide use. …”
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A Fine-Grained Aircraft Target Recognition Algorithm for Remote Sensing Images Based on YOLOV8 by Xiao-Nan Jiang, Xiang-Qian Niu, Fan-Lu Wu, Yao Fu, He Bao, Yan-Chao Fan, Yu Zhang, Jun-Yan Pei

“…Fine-grained recognition plays a pivotal role in the field of remote sensing image analysis, particularly in critical applications such as reconnaissance and early warning, intelligence analysis, and intelligent interpretation. …”
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Computer-Aided Construction and Evaluation of Poly-L-Lysine/Hyodeoxycholic Acid Nanoparticles for Hemorrhage and Infection Therapy by Qin Qin, Wenxing Wu, Ling Che, Xing Zhou, Diedie Wu, Xiaohui Li, Yumin Yang, Jie Lou

“…Developing a multifunctional nano-drug capable of simultaneously controlling bleeding, preventing infection, and promoting wound healing is critical. This study aimed to design and evaluate a nanoparticle-based solution to address these challenges effectively. …”
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Effect of molybdenum supply on crop performance through rhizosphere soil microbial diversity and metabolite variation by Muhammad Shoaib Rana, Muhammad Shoaib Rana, Dikhnah Alshehri, Dikhnah Alshehri, Rui-Long Wang, Muhammad Imran, Yousif Abdelrahman Yousif Abdellah, Faiz Ur Rahman, Marfat Alatawy, Hanaa Ghabban, Hanaa Ghabban, Amany H. A. Abeed, Cheng-xiao Hu

“…Metabolite profiling revealed 8 and 10 significantly differential metabolites in maize and soybean, respectively, under +Mo treatment, highlighting the critical role of Mo in metabolite variation. Overall, these findings emphasize the importance of Mo in shaping soil microbial diversity by altering metabolite composition, which in turn may enhance the nutrient availability, nutrient uptake, and plant performance.…”
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Cloning, expression, and purification of fusion antigens MPT83 and ESAT6 from the local strain of Mycobacterium tuberculosis in Escherichia coli as a seed vaccine candidate against... by Rusdina Bte Ladju, Ahyar Ahmad, Abdul Karim, Rugaiyah Arfah, Rosana Agus, Najdah Hidayah, Muhammad Nasrum Massi, Astutiati Nurhasanah, Harningsih Karim, Irda Handayani

“…The development of more potent TB vaccines is critical to complement overall TB control strategies and overcome the growing challenge of drug resistance. …”
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Influence of cement particle size, ultra-fine fly ash, and ultra-fine silica fume on the physical and microscopic properties of slurry by Kai Wang, Siyang Guo, Hua Yuan, Jiahui Ren, Pengyu Chen, Qihao Zhang

“…Considering the rapid development of the engineering industry, cement grouting materials are critical in many projects. However, cement production is energy-intensive and relies on non-renewable raw materials. …”
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Evaluating Normalization Methods for Robust Spectral Performance Assessments of Hyperspectral Imaging Cameras by Siavash Mazdeyasna, Mohammed Shahriar Arefin, Andrew Fales, Silas J. Leavesley, T. Joshua Pfefer, Quanzeng Wang

“…These findings provide a foundation for standardized performance testing of HSI-based medical devices, promoting the adoption of high-quality HSI technology for critical applications such as early cancer detection.…”
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Mechanistic insights into gut microbe derived siderophores and PHD2 interactions with implications for HIF-1α stabilization by Jainabbi Irshad Ahmed Patel, Jagadeesha Poyya, Apeksha Padakannaya, Namrata Manjunath Kurdekar, Ajay Sathayanarayan Khandagale, Chandrashekhar Gajanan Joshi, Santosh R. Kanade, Kapaettu Satyamoorthy

“…Molecular dynamics simulations confirmed stable ligand interactions with PHD2, highlighting HIS313 and ASP315 as critical for inhibition. Principal Component Analysis (PCA) and Free Energy Landscape (FEL) analyses underscored conformational changes and binding stability, suggesting that these interactions may stabilize PHD2’s active site and have potential therapeutic implications. …”
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Role of YAP/TAZ in bone diseases: A transductor from mechanics to biology by Xin Chen, Xing Ji, Zhaobai Lao, Bin Pan, Yu Qian, Wanlei Yang

“…Thus, this review aims to provide an in-depth examination of YAP/TAZ's critical role in the interpretation of mechanical stimuli to biological signals, with a special emphasis on their involvement in bone cell mechanosensing, mechanotransduction, and mechanoresponse.The translational potential of this article: Clinically, appropriate stress stimulation promotes fracture healing, while bed rest can lead to disuse osteoporosis and excessive stress can cause osteoarthritis or bone spurs. …”
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NavBLIP: a visual-language model for enhancing unmanned aerial vehicles navigation and object detection by Ye Li, Li Yang, Meifang Yang, Fei Yan, Tonghua Liu, Chensi Guo, Rufeng Chen

“…While these methods have seen some success, they frequently encounter limitations in dynamic environments, where robustness and computational efficiency become critical for real-time performance. Additionally, these methods often fail to effectively integrate multimodal inputs, which restricts their adaptability and generalization capabilities when facing complex and diverse scenarios.MethodsTo address these challenges, we introduce NavBLIP, a novel visual-language model specifically designed to enhance UAV navigation and object detection by utilizing multimodal data. …”
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Safe-and-sustainable-by-design redox active molecules for energy storage applications by Clemens Wolf, Janine Maier, Julia Wenger, Georg Rudelstorfer, Christian Leypold, Julia Voglhuber-Höller, Matiss Reinfelds, Andrea Weiner, Arantza Muriana, Susanne Lux, Claudia Mair-Bauernfeind, Andreas Falk, Stefan Spirk

“…(Social) life cycle assessment focused on the workflow from sourcing, processing and generation of intermediate products to the quinone used in the redox flow batteries and revealed important insights, highlighting critical steps in the process chain. Additionally, we identified two specific points of intervention regarding solvent and quinone choice, based on sustainability parameters. …”
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Evolving perspectives in dental marketing: A study of Jordanian dentists' attitudes towards advertising and practice promotion by Rami J. Anshasi, Nizar Alsubahi, Ahmad A. Alhusein, Abd Alwali Lutfi Khassawneh, Mahmaod Alrawad, Adi Alsyouf

“…Proponents of advertising argue that it benefits the community by enhancing the quality of dental services (51.9 %), lowering prices through competition (26.7 %), providing educational information (74.3 %), and assisting the community in making informed choices (59.7 %). Conversely, critics contend that advertising undermines the public's perception of the profession (33.9 %) and diminishes the trustworthiness of dentists (24.7 %). …”
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CCD Standard Curve Fitting for Microarray Detection Base on Multi-Layer Perceptron by Zhenhua Gan, Dongyu He, Peishu Wu, Baoping Xiong, Nianyin Zeng, Fumin Zou, Feng Guo, Qin Bao, Fengyan Zhao

“…However, the standard curve is critical to the highly accurate measuring of the instrument. …”
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Secretory mitophagy: an extracellular vesicle-mediated adaptive mechanism for cancer cell survival under oxidative stress by Purva V. Gade, Angela Victoria Rojas Rivera, Layla Hasanzadah, Sofie Strompf, Thomas Raymond Philipson, Matthew Gadziala, Atharva Tyagi, Arnav Bandam, Rithvik Gabbireddy, Fatah Kashanchi, Amanda Haymond, Lance A. Liotta, Marissa A. Howard

“…Mitophagy is a critically important survival mechanism in which toxic, aged, or defective mitochondria are segregated into mitophagosomes, which shuttle the damaged mitochondrial segments to the lysosome and proteasome for destruction. …”
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