Effects of early pulmonary rehabilitation exercise on the lung function and indicators of arterial blood gas analysis in patients with severe chronic obstructive pulmonary disease... by XU Nannan (徐楠楠), HONG Hanhan (洪涵涵)

Get full text

Type I IFN induces long-chain acyl-CoA synthetase 1 to generate a phosphatidic acid reservoir for lipotoxic saturated fatty acids by Shelley Barnhart, Masami Shimizu-Albergine, Eyal Kedar, Vishal Kothari, Baohai Shao, Melissa Krueger, Cheng-Chieh Hsu, Jingjing Tang, Jenny E. Kanter, Farah Kramer, Danijel Djukovic, Vadim Pascua, Yueh-Ming Loo, Lucrezia Colonna, Sadie J. Van den Bogaerde, Jie An, Michael Gale, Jr., Karen Reue, Edward A. Fisher, Sina A. Gharib, Keith B. Elkon, Karin E. Bornfeldt

Get full text

Microenvironmental G protein‐coupled estrogen receptor‐mediated glutamine metabolic coupling between cancer‐associated fibroblasts and triple‐negative breast cancer cells governs t... by Chongwu He, Meixi Peng, Xiaoqiang Zeng, Hanzhi Dong, Zhengkui Sun, Jiawei Xu, Manran Liu, Liyan Liu, Yanxiao Huang, Zhiqiang Peng, Yu‐An Qiu, Chunling Jiang, Bin Xu, Tenghua Yu

“…Conclusions The study identifies GPER as a critical mediator of metabolic coupling between CAFs and TNBC cells, primarily through glutamine metabolism. …”
Get full text

Development and Validation of a Diagnostic Model for Stanford Type B Aortic Dissection Based on Proteomic Profiling by Zhao Z, Chen T, Liu Q, Hu J, Ling T, Tong Y, Han Y, Zhu Z, Duan J, Jin Y, Fu D, Wang Y, Pan C, Keyoumu R, Sun L, Li W, Gao X, Shi Y, Dou H, Liu Z

“…Zihe Zhao,1,* Taicai Chen,2,3,* Qingyuan Liu,4 Jianhang Hu,1 Tong Ling,2,3 Yuanhao Tong,5 Yuexue Han,1 Zhengyang Zhu,6 Jianfeng Duan,7 Yi Jin,1 Dongsheng Fu,1 Yuzhu Wang,1 Chaohui Pan,1 Reyaguli Keyoumu,1 Lili Sun,1 Wendong Li,1 Xia Gao,8,9 Yinghuan Shi,2,3 Huan Dou,10,11 Zhao Liu1 1Department of Vascular Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, People’s Republic of China; 2The State Key Laboratory for Novel Software Technology, Nanjing University, Nanjing, People’s Republic of China; 3National Institute of Healthcare Data Science, Nanjing University, Nanjing, People’s Republic of China; 4Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, People’s Republic of China; 5Department of Thoracic Surgery, BenQ Medical Center, Affiliated BenQ Hospital of Nanjing Medical University, Nanjing, Jiangsu, People’s Republic of China; 6Department of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, People’s Republic of China; 7Department of Critical Care Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, People’s Republic of China; 8Department of Otolaryngology, Head and Neck Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, People’s Republic of China; 9Jiangsu Provincial Key Medical Discipline (Laboratory), Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, People’s Republic of China; 10The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing, People’s Republic of China; 11Jiangsu Key Laboratory of Molecular Medicine, Medical School, Nanjing University, Nanjing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhao Liu, Department of Vascular Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, #321 Zhongshan Road, Nanjing, 210008, People’s Republic of China, Email liuzhao@nju.edu.cn Huan Dou, The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing, People’s Republic of China, Email douhuan@nju.edu.cnPurpose: Stanford Type B Aortic Dissection (TBAD), a critical aortic disease, has exhibited stable mortality rates over the past decade. …”
Get full text

Low-dose trimethoprim-sulfamethoxazole for the treatment of Pneumocystis jirovecii pneumonia (LOW-TMP): protocol for a phase III randomised, placebo-controlled, dose-comparison tri... by Andrea Benedetti, Cecilia T Costiniuk, Kosar Khwaja, Andrew Johnson, Barret Rush, Darrell Tan, Ranjani Somayaji, Salman Qureshi, Michaeline McGuinty, Nicole Ezer, Sara Belga, Emily G. McDonald, Zahra N. Sohani, Guillaume Butler-Laporte, Andrew Aw, Alex Carignan, Matthew P. Cheng, Bryan Coburn, Dan Gregson, Alexander Lawandi, Victor Leung, Sylvain Lother, Derek MacFadden, Leighanne Parkes, Valerie Roy, Ilan Schwartz, Miranda So, Emilie Trinh, Todd C. Lee

Get full text

The role of OCO-3 XCO₂ retrievals in estimating global terrestrial net ecosystem exchanges by X. Wang, F. Jiang, F. Jiang, F. Jiang, H. Wang, Z. Zhang, M. Wu, J. Wang, W. He, W. Ju, W. Ju, J. M. Chen, J. M. Chen

Get full text

Diagnosis, screening, and follow-up of patients with familial interstitial lung disease: Results from an international survey by Emil Vilstrup Moen, Thomas Skovhus Prior, Michael Kreuter, Wim A. Wuyts, Maria Molina-Molina, Marlies Wijsenbeek, Antonió Morais, Argyrios Tzouvelekis, Christopher J. Ryerson, Fabian Caro, Ivette Buendia-Roldan, Jesper M. Magnusson, Joyce S. Lee, Julie Morisett, Justin M. Oldham, Lauren K. Troy, Manuela Funke-Chambour, Maria Laura Alberti, Raphael Borie, Simon L. F. Walsh, Sujeet Rajan, Yasuhiro Kondoh, Yet H Khor, Elisabeth Bendstrup

Get full text

Epistemic Roots, Universal Routes and Ontological Roofs of African “Ritual Archives”: Disciplinary Formations in African Thought by Oluwatoyin Vincent Adepoju

“…This mapping of convergence and divergence contributes to working out the continuum in Yoruba thought between a critical and experiential configuration and a belief system. …”
Get full text

Research trends and hotspots in post-stroke speech rehabilitation: A bibliometric analysis by Nan Huang, Kang Zou, Fang Liu, Zhen Su, Long Chen, Yanbiao Zhong, Yun Luo, Maoyuan Wang, Li Xiao

“…Speech and language disorders notably impair communication and restrict social engagement, making speech rehabilitation a critical intervention. However, comprehensive bibliometric analyses on post-stroke language rehabilitation are limited, restricting understanding of progress in this field. …”
Get full text

Presenting a Framework of Effective Factors on the Implementation of Policies in the Field of Protection and Exploitation of Forests in the North of the Country by Davoud Hosseinpoor, Seyed Mahdi Alvani, Hossein Aslipour, Aghil Ghorbani Paji

“…Objective Environmental protection in Iranian law is designated as a public duty, reflecting its critical importance. The complex, cross-sectoral, and multi-dimensional nature of environmental protection mandates that this responsibility be shared broadly across various sectors. …”
Get full text

Network Meta-Analysis of Factors Influencing the Carbon Sink Capacity of Urban Park Green Spaces by Yutong JI, Tianyi LIN, Lian LIU, Xiong LI

“…In light of the increasingly prominent role of urban green spaces in mitigating climate change, the research also seeks to highlight strategies that balance ecological functions with urban recreational and aesthetic needs.MethodThis research employs the network Meta-analysis method to explore the critical factors influencing the carbon sequestration potential of urban park green spaces, and conduct a systematic quantitative assessment of their respective carbon sink capacity. …”
Get full text

Outcome from out-of-hospital cardiac arrest managed by the pre-hospital emergency medical system in Martinique, a French Caribbean Overseas Territory by Florian Negrello, Jonathan Florentin, Romain Jouffroy, Vianney Aquilina, Rishika Banydeen, Rémi Neviere, Dabor Resiere, Moustapha Drame, Papa Gueye

Get full text

Toward trustworthy COVID-19 interventions: Building vaccine trust through community-university partnerships. by Laura A Bray, Lori L Jervis, Amanda E Janitz, Laura Ross, Gloria Tallbull, Timothy M VanWagoner, CATCH-UP Vaccines Team

“…Prior research identifies trust as critical to increase vaccine acceptance and uptake. …”
Get full text

Effective strategies for controlling physical fitness in 7-8 year old tennis players for optimal health and performance by Oleg Shevchenko, Marina Jagiello

“…Controlling physical fitness in 7-8 year old tennis players is particularly important as this is a critical period for physical development, and habits formed during this age can have long-lasting effects on health outcomes. …”
Get full text

A Person-Based Adaptive Traffic Signal Control Method with Cooperative Transit Signal Priority by Wei-Hsun Lee, Hsuan-Chih Wang

“…Real-time traffic signal control has long been a critical way to improve traffic congestion. Transit Signal Priority (TSP) is seen as a cost-effective way to reduce travel time variability. …”
Get full text

Cross-layer latency analysis for 5G NR in V2X communications. by Jorge Horta, Mario Siller, Salvador Villarreal-Reyes

“…The protocol layer approach gives the model sufficient granularity to identify critical behaviors that significantly impact performance. …”
Get full text

Multidimensional Analysis of PANoptosis-Related Molecule CASP8: Prognostic Significance, Immune Microenvironment Effect, and Therapeutic Implications in Hepatocellular Carcinoma by Fei Peng, Fang Zhu, Baodi Cao, Liang Peng

“…Biological enrichment analysis revealed CASP8’s association with critical cellular activities and immune responses. …”
Get full text

The problem of “harm” in the theory of international relations by M. A. Gadzhiev

“…In addition, based on the philosophy of critical realism, Alex Hoseason suggested that not only actors in international relations, but also social structures can cause harm. …”
Get full text

Exploring The Financial Dynamics Of Green Building Adoption: Insights From Indonesia by Sutikno Sutikno, Sarwono Hardjomuljadi, Hendrik Sulistio, M. Agung Wibowo, Suyono Dikun

“…The findings spotlight 10 critical green building factors pivotal for securing certification, alongside unveiling correlations between initial costs, operational costs, and life cycle costs. …”
Get full text