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  1. 16181

    Risk Index Model of Property and Cargo Insurance Claims Based on Precipitation in Hunan by Peng Weiying, Li Yueyong, Tan Shiqi, Li Hao, Guan Jianwen, Liao Chunhua, Zhou Wei, Xie Ruiheng

    Published 2025-01-01
    “…Notably, 48-hour accumulated precipitation emerges as the most critical factor affecting claims, followed closely by 72-hour accumulated precipitation. …”
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  2. 16182

    The proof is in the pudding: patient engagement in studying cannabidiol in mild cognitive impairment by Antonia Keck, Julia-Sophia Scheuermann, Petra Scheerbaum, Elmar Graessel, Kirsten R. Müller-Vahl

    Published 2025-01-01
    “…Abstract Background Patient engagement (PE) in clinical trials has gained importance yet remains uncommon, particularly in patients with mild cognitive impairment (MCI), a critical precursor to Alzheimer’s disease (AD). Cannabidiol (CBD) shows potential in slowing MCI progression due to its neuroprotective and anti-inflammatory properties. …”
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  3. 16183
  4. 16184

    Cellular Cholesterol Loss Impairs Synaptic Vesicle Mobility via the CAMK2/Synapsin-1 Signaling Pathway by Atikam Qurban, Mengqi Zhang, Hengbing Zu, Kai Yao

    Published 2025-01-01
    “…Our study indicates a critical role for cellular cholesterol deficiency in AD-related synaptopathy, thus highlighting the potential for targeting cellular cholesterol metabolism in therapeutic strategies.…”
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  5. 16185

    Incidence, trends and patterns of female breast, cervical, colorectal and prostate cancers in Antigua and Barbuda, 2017–2021: a retrospective study by Andre A. N. Bovell, Thendo Ramaliba, Sekeena O. Goodwin, Joycelyn C. Phillip, Jabulani Ncayiyana, Themba G. Ginindza

    Published 2025-01-01
    “…In Antigua and Barbuda, understanding the burden of common cancers such as female breast, cervical, colorectal and prostate cancers is critical. This study aimed to assess the incidence, trends, and patterns of these four cancers from 2017 to 2021. …”
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  6. 16186
  7. 16187

    Social Media Use and Oral Health–Related Misconceptions in Saudi Arabia: Cross-Sectional Study by Rahaf Hamdan BinHamdan, Salwa Abdulrahman Alsadhan, Arwa Zohair Gazzaz, AlBandary Hassan AlJameel

    Published 2025-02-01
    “…In Saudi Arabia, where platforms like WhatsApp, Snapchat, and Instagram are widely used, the quality and credibility of oral health information shared digitally remain critical issues. Misconceptions about oral health can negatively influence individuals’ behaviors and oral health outcomes. …”
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  8. 16188

    Automatic segmentation model and machine learning model grounded in ultrasound radiomics for distinguishing between low malignant risk and intermediate-high malignant risk of adnex... by Lu Liu, Wenjun Cai, Feibo Zheng, Hongyan Tian, Yanping Li, Ting Wang, Xiaonan Chen, Wenjing Zhu

    Published 2025-01-01
    “…The machine learning model exhibited commendable classification capability and outperformed the diagnostic performance of less-experienced radiologists. Critical relevance statement The ultrasound radiomics-based machine learning model holds the potential to elevate the professional ability of less-experienced radiologists and can be used to assist in the clinical screening of ovarian cancer. …”
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  9. 16189
  10. 16190

    Multi-modal characterisation of early-stage, subclinical cardiac deterioration in patients with type 2 diabetes by Ambre Bertrand, Andrew Lewis, Julia Camps, Vicente Grau, Blanca Rodriguez

    Published 2024-10-01
    “…Detection of early signs of cardiac deterioration in T2DM patients is critical for prevention. Our goal is to quantify T2DM-driven abnormalities in ECG and cardiac imaging biomarkers leading to cardiovascular disease. …”
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  11. 16191
  12. 16192

    Conflict-associated wounds and burns infected with GLASS pathogens in the Eastern Mediterranean Region: A systematic review by Amelia Wild, Clare Shortall, Omar Dewachi, Carine Naim, Alex Green, Sarah Hussain, Aula Abbara

    Published 2025-02-01
    “…A total of 1,942 distinct microbiological isolates were reported, representing all four critical and high priority GLASS pathogen categories. …”
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  13. 16193

    Proteomic analysis of spinal dorsal horn in prior exercise protection against neuropathic pain by Binglin Chen, Jiabao Guo, Chan Gong, Chenchen Zhu, Yang Wu, Shengbo Wang, Yili Zheng, Haixia Lu

    Published 2025-01-01
    “…GO and KEGG enrichment analysis revealed that oxygen transport capacity and the complement and coagulation cascades may be the critical mechanism by which prior exercise protects against NP. …”
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  14. 16194

    Delta Neutrophil Index in Coronary Artery Bypass Surgery: An Innovation in Postoperative Mortality Assessment by Bilgiç A, Toprak B, Kaya H

    Published 2025-02-01
    “…A 1-unit increase in postoperative DNI measurement was associated with a 10.21-fold (95% Confidence Interval: 5.08– 20.05) increase in the risk of death.Conclusion: Elevated DNI values are strong independent predictors of postoperative mortality, underscoring its critical role in perioperative risk assessment for CABG patients. …”
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  15. 16195

    Novel Nanozyme-Based Multicomponent in situ Hydrogels with Antibacterial, Hypoxia-Relieving and Proliferative Properties for Promoting Gastrostomy Tube Tract Maturation by Xiao F, Yan B, Yuan T, He Y, Zhang X, He X, Peng W, Xu Y, Cao J

    Published 2025-01-01
    “…The hydrogel group exhibited a significant promotion in collagen content and reduction in HIF-1α, which effectively hastened tract maturation.Conclusion: Therefore, our study provides new and critical insights into a strategy to design bioactive hydrogels with multiple functions, which can open up a new avenue for accelerated wound healing after gastrostomy. …”
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  16. 16196

    Sputum Smear Positive Pulmonary Tuberculosis Diagnostic Dropout Rate in Public Health Facilities, Addis Ababa, Ethiopia by Daniel Melese Desalegn, Kumera Terfa Kitila, Boja Dufera Taddese, Tinsae Kidanemariam Hailu, Tariku Takle Dinku, Kassahun Demisse Asferie, Hanna Mekonnen Balcha, Chalachew Sisay Gebeyehu, Girmay Medhin

    Published 2019-01-01
    “…This implies such dropout patients without completing diagnosis are critical as infected individuals remain untreated in the community, providing more opportunities for transmission of the disease and adversely affecting the epidemic. …”
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  17. 16197

    CXCR4 promotes tumor stemness maintenance and CDK4/6 inhibitors resistance in ER-positive breast cancer by Qiangfeng Shi, Wang Yang, Yiye Ouyang, Yujie Liu, Zijie Cai

    Published 2025-01-01
    “…Results In our study, we focused on cancer stem cells, a critical contributor to cancer metastasis and therapy resistance, and detected an upregulation of stemness in our established palbociclib-resistant ER-positive breast cancer cells. …”
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  18. 16198
  19. 16199
  20. 16200

    An ensemble machine learning-based performance evaluation identifies top In-Silico pathogenicity prediction methods that best classify driver mutations in cancer by Subrata Das, Vatsal Patel, Shouvik Chakravarty, Arnab Ghosh, Anirban Mukhopadhyay, Nidhan K. Biswas

    Published 2025-01-01
    “…Abstract Background and objective Accurate identification and prioritization of driver-mutations in cancer is critical for effective patient management. Despite the presence of numerous bioinformatic algorithms for estimating mutation pathogenicity, there is significant variation in their assessments. …”
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