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15861
Detection of low frequency artemisinin resistance mutations, C469Y, P553L and A675V, and fixed antifolate resistance mutations in asymptomatic primary school children in Kenya
Published 2025-01-01“…Abstract Background To understand the emergence and spread of drug-resistant parasites in malaria-endemic areas, accurate assessment and monitoring of antimalarial drug resistance markers is critical. Recent advances in next-generation sequencing (NGS) technologies have enabled the tracking of drug-resistant malaria parasites. …”
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15862
An Optimized Liquid Chromatography–Mass Spectrometry Method for Ganglioside Analysis in Cell Lines
Published 2024-10-01“…Neuroblastoma, a pediatric cancer of the sympathetic nervous system, is treated with intensive chemotherapy, radiation, and an antibody targeting the GD2 ganglioside. Gangliosides are critical in neuroblastoma development and serve as therapeutic targets, making it essential to establish a reliable, rapid, and cost-effective method for profiling gangliosides, particularly one capable of isomeric separation of intact species. …”
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15863
Association of HIV infection and hospitalization among mpox cases: a systematic review and meta-analysis
Published 2025-01-01“…Conclusion HIV infection is associated with a statistically significant increased risk of hospitalization in mpox cases. There is a critical need for integrated care and enhanced surveillance, especially in populations with high HIV prevalence. …”
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15864
Higher education students' perceptions of ChatGPT: A global study of early reactions.
Published 2025-01-01“…While ChatGPT was perceived as effective in potentially improving AI literacy, digital communication, and content creation skills, it was less useful for interpersonal communication, decision-making, numeracy, native language proficiency, and the development of critical thinking skills. Students also felt that ChatGPT would boost demand for AI-related skills and facilitate remote work without significantly impacting unemployment. …”
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15865
Effect of TNF-α-Induced Sclerostin on Osteocytes during Orthodontic Tooth Movement
Published 2019-01-01“…Osteocyte-derived RANKL is critical in bone resorption during OTM. Additionally, tumor necrosis factor-α (TNF-α) is important in osteoclastogenesis during OTM. …”
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15866
Molecular cloning and expression dynamics of Atrogin-1 in muscle tissue of Russian sturgeon (Acipenser gueldenstaedtii) under high salt stress
Published 2025-03-01“…Atrogin-1, a muscle-specific ubiquitin ligase, is integral to the regulation of protein degradation and plays a pivotal role in the targeted degradation of critical muscle signaling proteins, which can lead to skeletal muscle dysfunction. …”
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15867
GC-derived exosomal circMAN1A2 promotes cancer progression and suppresses T-cell antitumour immunity by inhibiting FBXW11-mediated SFPQ degradation
Published 2025-01-01“…Conclusions Our work confirms the critical role of exosomal circMAN1A2 in the progression and immunosuppression of GC. …”
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15868
Unveiling <i>DENND2D</i> as a Novel Prognostic Biomarker for Prostate Cancer Recurrence: From Gene to Prognosis
Published 2024-12-01“…Emerging evidence suggests a critical role for differentially expressed in normal and neoplastic cell (<i>DENN</i>) domain-containing genes in oncogenesis; however, their implications in prostate cancer and BCR risk remain underexplored. …”
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15869
Advancing health equity: evaluating AI translations of kidney donor information for Spanish speakers
Published 2025-01-01“…ChatGPT, an AI language model with sophisticated natural language processing capabilities, has been identified as a promising tool for translating critical health information into Spanish. This study aims to assess ChatGPT’s translation efficacy to ensure the information provided is accurate and culturally relevant.MethodsThis study utilized ChatGPT versions 3.5 and 4.0 to translate 27 frequently asked questions (FAQs) from English to Spanish, sourced from Donate Life America’s website. …”
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15870
NF-κB-Specific Suppression in Cardiomyocytes Unveils Aging-Associated Responses in Cardiac Tissue
Published 2025-01-01“…These findings suggest that NF-κB plays a critical regulatory role in cardiac aging, influencing both cellular senescence and molecular damage pathways. …”
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15871
The Impact of Optical Undersampling on the Ca2+ Signal Resolution in Ca2+ Imaging of Spontaneous Neuronal Activity
Published 2025-01-01“…This study investigated whether increasing the sampling rate preserves critical information that may be missed at slower acquisition speeds. …”
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15872
Investigating the feasibility of developing a collective action for biological control of fall armyworm among smallholder farmers in rural communities of Zambia
Published 2023-05-01“…In addition, collective action has been acknowledged to be a critical component for invasive species management, but is still poorly studied in low- and middle-income countries (LMIC) where the national plant health system, in-place to prevent and manage biological invasions, is limited. …”
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15873
Evaluating the dual impact of microbial activity and aged refuse layers on landfill leachate clogging: An experimental and LCA perspective
Published 2025-02-01“…Conclusion: This study provides critical insights into microbial contributions to landfill leachate-induced clogging and emphasizes the importance of incorporating environmental considerations into landfill management. …”
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15874
Avoiding ‘second victims’ in healthcare: what support do staff want for coping with patient safety incidents, what do they get and is it effective? A systematic review
Published 2025-02-01“…This review illustrates a critical need to fund robust PSI-related intervention effectiveness studies to provide organisations with the evidence they need to make informed decisions when building PSI support programmes.PROSPERO registration number CRD42022325796.…”
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15875
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15876
Comparative effects of methamphetamine, cannabis, and polysubstance use on oral health
Published 2025-01-01“…HU-DBI scores indicated poorer oral health behaviors in substance users, though the difference was not statistically significant (p=0.053).DiscussionThe study reveals that all substance use groups, including MA, THC, and PS users, exhibit significantly poorer oral health outcomes, with higher DMFT scores and worse oral health behaviors compared to the control group, highlighting the critical need for comprehensive dental care interventions for individuals with substance use disorders.Clinical Trial Registrationhttps://clinicaltrials.gov/study/NCT06640712, identifier NCT06640712.…”
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15877
Housing Price Forecasting Using AI (LSTM)
Published 2023-12-01“…ObjectiveForecasting the asset prices in any market is an inseparable and critical part of research on markets. Obtaining a credible prediction of an asset's potential future price provides valuable information for investors. …”
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15878
Performance of emergency triage prediction of an open access natural language processing based chatbot application (ChatGPT): A preliminary, scenario-based cross-sectional study
Published 2023-07-01“…It may be useful when determining the cases requiring critical care. When trained with more medical knowledge, ChatGPT may be more accurate for other triage category predictions.…”
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15879
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15880
Prediksi Mahasiswa Drop-Out Di Universitas XYZ
Published 2024-12-01“…Abstract Accreditation and reputation are critical factors for higher education institutions, including XYZ University. …”
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