Improving the integrity and reproducibility of research that uses antibodies: a technical, data sharing, behavioral and policy challenge by M. Biddle, P. Stylianou, M. Rekas, A. Wright, J. Sousa, D. Ruddy, M. I. Stefana, K. Kmiecik, A. Bandrowski, R.A. Kahn, C. Laflamme, E. M. Krockow, H.S. Virk

“…Here we argue that the determinants of end-user antibody choice and use are critical, and under-addressed, behavioral drivers of this problem. …”
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Harnessing defects in Ag/CeO2 for enhanced photocatalytic degradation of antibiotic in water: Structural characteristics, in-depth insights on mechanism, degradation pathway by Ajit Kumar Dhanka, Emerson C. Kohlrausch, Raghabendra Samantray, Vinod Kumar, Balaram Pani, Nityananda Agasti

“…A plausible mechanism is proposed based on critical analysis of the results from the characterization techniques of the nanocomposites and photocatalytic experiments. …”
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Revealing the core suppression effects of various Di (2-ethylhexyl) phthalate exposure on early meiosis progression in postnatal male mice via single-cell RNA sequencing by Baoquan Han, Lei Hua, Shuai Yu, Wei Ge, Cong Huang, Yu Tian, Chunxiao Li, Jiamao Yan, Tian Qiao, Jiachen Guo, Dongliang Lu, Bin Wang, Diya Cai, Yunqi Zhang, Shaolin Liang, Jianjuan Zhao, Qi Hou, Wei Shen, Zhongyi Sun

“…DEHP exposure resulted in a substantial decrease in the expression of the Trp53 gene, which in turn down-regulated three critical downstream genes (Stmn1, Tubb5, and Ccnb1) that are implicated in spindle organization from a mechanistic perspective. …”
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Genomic scans for selection and runs of homozygosity in southern Italian turkey populations by Medhat S. Saleh, Vincenzo Landi, Martijn F.L. Derks, Gerardo Centoducati, Martien A.M. Groenen, Pasquale De Palo, Elena Ciani, Nicola Pugliese, Elena Circella, Antonio Camarda

“…Understanding the genomic patterns of BAS-APU turkeys is critical for effective breeding and preservation strategies. …”
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Global, regional and national epidemiological trends of multiple myeloma from 1990 to 2021: a systematic analysis of the Global Burden of Disease study 2021 by Linmin Zhuge, Xiaowu Lin, Ziwei Fan, Mengxian Jia, Chaowei Lin, Minyu Zhu, Honglin Teng, Guoliang Chen

“…Targeted preventive interventions and improvements in diagnosis, treatment, and care are critical, especially in underdeveloped regions, to address the growing global burden of MM.…”
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Trends in incidence, mortality, and DALYs of cystic echinococcosis in Central Asia from 1992 to 2021: an age-period-cohort analysis by Wulan Talafuhan, Kaibinuer Tuoheti, Ye Lixia, Qi Shuang, Mieyier Yeerjiang, Guzalinuer Aizezi, Wei Jingjing, Peierdun Mijiti, Peierdun Mijiti

“…This study analyzed trends in CE incidence, mortality, and disability-adjusted life years (DALYs) from 1992 to 2021 in Central Asia; compared them with global data; and explored variations by gender, age group, and country to identify critical factors in disease control.MethodsUsing data from the Global Burden of Disease Study 2021 (GBD 2021), we analyzed long-term trends in the incidence, mortality, and DALY rates of CE in Central Asia. …”
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Transcription Factor E2F-1 Is Upregulated in Human Gastric Cancer Tissues and Its Overexpression Suppresses Gastric Tumor Cell Proliferation by Qiang Xiao, Lei Li, Yubo Xie, Ning Tan, Changqing Wang, Junyi Xu, Keyi Xia, Kevin Gardner, Qingdi Q. Li

“…The E2F family members play a critical role in cell cycle regulation and other biological processes in the cell. …”
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Effect of potato glycoside alkaloids on mitochondria energy metabolism of Fusarium solani, the root rot pathogen of Lycium barbarum by Ruiyun Li, Bin Wang, Wei Chen, Chongqing Zhang, Nan Li, Yupeng Wang, Yuke Yan, Yuyan Sun, Jing He, Jing He

“…Furthermore, a total of 195 pathways were identified through KEGG analysis, with significant enrichment in critical pathways including pentose and glucuronate interconversions, propanoate metabolism, various types of N-glycan biosynthesis, the pentose phosphate pathway, and carbon fixation in photosynthetic organisms. …”
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The short-, medium-, and long-term prevalence of physical health comorbidities in first-episode psychosis: a systematic review and meta-analysis protocol [version 2; peer review: 3... by Michael Norton, Brian O'Donoghue, Mary Clarke, Karen O'Connor, Jennifer Murphy, Anna Zierotin

“…Risk of bias will be assessed using the Joanna Briggs Institute Critical Appraisal Checklist. A meta-analysis of the short-, medium-, and long-term prevalence of cardiovascular, metabolic, cancer, and respiratory outcomes and a narrative synthesis will be conducted. …”
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Enhanced AC/DC optimal power flow via nested distributed optimization for AC/VSC-MTDC hybrid power systems by Haixiao Li, Pedro P. Vergara, Robert Dimitrovski, Hongjin Du, Aleksandra Lekić

“…However, significant challenges exist in exploiting coordinated operations for such AC/VSC-MTDC hybrid power systems. One of the most critical issues is how to achieve the optimal operation of such wide-area systems involving several power entities with as minimal communication burden as possible. …”
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Mechanism of Threshold Voltage Instability in Double Gate α-IGZO Nanosheet TFT Under Bias and Temperature Stress by Muhammad Aslam, Shu-Wei Chang, Yi-Ho Chen, Yao-Jen Lee, Yiming Li, Wen-Hsi Lee

“…The reliably reported double gate IGZO nanosheet TFTs (DG-IGZO-NS-TFTs) are tested under positive and negative bias stress at variant temperatures, and the resulting modulations are analyzed critically. The reported DG-IGZO-NSTFTs exhibit a negative side threshold voltage shift (<inline-formula> <tex-math notation="LaTeX">$\Delta$ </tex-math></inline-formula>Vth) accompanied by an increase in Ion/Ion(0) under negative bias temperature stress (NBTS) at elevated temperatures, which indicates the presence of additional charges. …”
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Epidemiological features and risk factors of human psittacosis in Hangzhou City, eastern China by Zhou Sun, Ke Xu, Liangliang Huo, Xingliang Zhang, Yi Wang, Yonghui Gong, Bingbing Chen

“…A community-based 1:3 matched case-control study was performed to investigate the risk factors associated with Chlamydia psittaci infection.ResultsDuring the study period, 137 confirmed cases of human psittacosis were identified through laboratory tests, of which 24 (17.52%) were classified as critical cases, including one fatality. The epidemic curve indicated that the majority of cases occurred between October and March. …”
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Progress in prediction of photocatalytic CO2 reduction using machine learning approach: A mini review by Md Mohshin Ali, Md. Arif Hossen, Azrina Abd Aziz

“…The fundamentals of PC-CO2R and the significance of utilizing ML models as a facilitative tool in photocatalysis are critically discussed in this review. Furthermore, the review outlines the commonly employed ML algorithms, presents recent progress, and identifies crucial parameters influencing PC-CO2R efficiency. …”
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Bone Marrow Stromal Cells Generate a Pro-Healing Inflammasome When Cultured on Titanium–Aluminum–Vanadium Surfaces with Microscale/Nanoscale Structural Features by David J. Cohen, Christine M. Van Duyn, Jingyao Deng, Musaddiq K. Lodi, Michelle B. Gallagher, James T. Sugar, Jeremy J. Rawlinson, Preetam Ghosh, Barbara D. Boyan, Zvi Schwartz

“…The surface topography and chemistry of titanium–aluminum–vanadium (Ti6Al4V) implants play critical roles in the osteoblast differentiation of human bone marrow stromal cells (MSCs) and the creation of an osteogenic microenvironment. …”
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Recent advances in the application of Mendelian randomization to chronic kidney disease by Chaofan Wen, Lanlan Chen, Dan Jia, Ziqi Liu, Yidan Lin, Guan Liu, Shuo Zhang, Baoshan Gao

“…New insights also reveal a substantial causal connection between both central and general obesity and CKD onset, while no significant links were found between genetically modified LDL cholesterol or triglyceride levels and kidney function.Conclusion This review not only presents the recent achievements of MR in CKD research but also illuminates the path forwards, underscoring critical unanswered questions and proposing future research directions in this dynamic field.…”
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Aetiological research on the health of migrants living in Germany: a systematic literature review by Oliver Razum, Florian Fischer, Ina Danquah, Claudia Hövener, Patricia Nayna Schwerdtle, Tracy Bonsu Osei, Isabel Mank, Raissa Sorgho

“…For quality appraisal, we used the Critical Appraisal Skills Programme checklists. Outcomes under investigation were categorised according to the WHO major disease groups, and their associations with risk factors were synthesised as a heat map.Results Out of 2407 articles retrieved, we included 68 publications with a total number of 864 518 participants. …”
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Antimicrobial Resistance Profile of E. coli Isolated from Raw Cow Milk and Fresh Fruit Juice in Mekelle, Tigray, Ethiopia by Haftay Abraha Tadesse, Netsenet Berhe Gidey, Kidane Workelule, Hagos Hailu, Seyfe Gidey, Abrha Bsrat, Habtamu Taddele

“…The current study supports the finding that raw milk and fruit juice can be regarded as critical source of pathogenic E. coli. This supports the need for strict monitoring and the implementation of effective hygienic and biosecurity measures in the whole food chain of these products as well as a prudent use of antimicrobials.…”
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Recent Advances in the Mechanisms of Postoperative Neurocognitive Dysfunction: A Narrative Review by Tingting Wang, Xin Huang, Shujun Sun, Yafeng Wang, Linlin Han, Tao Zhang, Tianhao Zhang, Xiangdong Chen

“…By bridging molecular insights with clinical practice, this review highlights the critical role of personalized anesthetic strategies in mitigating PND and improving cognitive recovery in elderly surgical patients. …”
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Genome-wide identification, characterization, and expression analysis of BZR transcription factor family in Gerbera hybrida by Qishan Luo, Gan Huang, Xiaohui Lin, Xiaojing Wang, Yaqin Wang

“…Abstract Background The BZR family genes encode plant-specific transcription factors as pivotal regulators of plant BR signaling pathways, critically influencing plant growth and development. …”
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Neonatal and perinatal mortality in the urban continuum: a geospatial analysis of the household survey, satellite imagery and travel time data in Tanzania by Lenka Benova, Claudia Hanson, Aliki Christou, Aline Semaan, Peter M Macharia, Jessie Pinchoff, Andrea B Pembe

“…Travel time to the nearest hospital was not associated with neonatal or perinatal mortality.Conclusion Addressing high rates of neonatal and perinatal mortality in densely populated urban areas is critical for Tanzania to meet national and global reduction targets. …”
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