PARP inhibitors as therapy for small cell lung carcinoma: A systematic review and meta-analysis of clinical trials by Samuel Pratama, Lowilius Wiyono, Martien Silviandy Setiawan, Brigitta Cindy Lauren

“…Methods: Studies reporting efficacy and safety of PARPi therapy for SCLC patients were searched across five databases with predetermined eligibility criteria in accordance with the PRISMA statement. Critical appraisal was done using suitable tools, outcomes were extracted, and analyzed. …”
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The Effect of Mesenchymal Stem Cell-Derived Exosomes and miR17-5p Inhibitor on Multicellular Liver Fibrosis Microtissues by Farnaz Sani, Mina Soufi Zomorrod, Negar Azarpira, Masoud Soleimani

“…Furthermore, the expression of collagen I (COL I) and α-smooth muscle actin (α-SMA) as critical matrix components, transforming growth factor beta (TGF-β), and miR-17-5p were measured. …”
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The mediating role of psychological equilibrium in the relationship between dietary variety and self-reported health among older adults in rural China by Zhaoquan Jiang, Zhaoxu Xu, Mingyue Zhou, Huijun Zhang, Shixue Zhou

“…Our results emphasize how critical it is to support a varied diet in order to improve SRH in older adults living in rural areas. …”
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Does sociality affect evolutionary speed? by Socias-Martínez, Lluís, Peckre, Louise Rachel

“…In trying to foster research in this direction, we offer a critical review of previous work on the link between evolutionary speed and sociality. …”
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Impact of Blended Learning Use On Agricultural Entrepreneurship Development by B. P Siriwardena, L. M Abeywickrama, A. L Sandika, N. P Vidanapathirana

“…Originality/value (State of the art): Understanding these characteristics is critical to entrepreneurial development in Sri Lanka, particularly in the field of agriculture. …”
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Harnessing Internet Search Data as a Potential Tool for Medical Diagnosis: Literature Review by Gregory J Downing, Lucas M Tramontozzi, Jackson Garcia, Emma Villanueva

“…However, challenges like privacy, bias, and scalability remain critical to its widespread adoption. ObjectiveWe aimed to explore the potential and challenges of using internet search data in medical diagnosis, with a specific focus on diseases and conditions such as cancer, cardiovascular disease, mental and behavioral health, neurodegenerative disorders, and nutritional and metabolic diseases. …”
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The acceptability of a novel seismocardiography device for measuring VO2 max in a workplace setting: a mixed methods approach by Anouska M Carter, Liam Humphreys, Alison Beswick, Sue Kesterton, Alex Bugg, Katharine Platts

“…This study suggests that practitioners delivering such services have a critical role to play in acceptability of health interventions at work, as employees will be heavily influenced by practitioner beliefs around coherence and effectiveness. …”
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Data-Oriented Analysis of Uplink Transmission in Massive IoT System With Limited Channel Information by Jyri Hamalainen, Rui Dinis, Mehmet C. Ilter

“…Recently, the paradigm of massive ultra-reliable low-latency Internet of Things (IoT) communications (URLLC-IoT) has gained growing interest. Reliable delay-critical uplink transmission in vehicular IoT is a challenging task since low-complex devices typically do not support multiple antennas or demanding signal processing tasks. …”
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The Impact of ‘Migration Potential’ on the Economic and Demographic Development of Donor and Recipient Countries by V. Yu. Ledeneva, A. Kh. Rakhmonov

“…Migration potential is approached as a variable that is both fluid and subject to modification. The research critically analyzes the multifaceted impacts – both advantageous and adverse – of migration on diverse sectors of life in donor and recipient countries. …”
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Digital breakthrough: will public administration be smart enough in a digital state and how smart are the elite and citizens by L. A. Vasilenko

“…The signs of the subject of management among citizens in modern management practice are revealed in terms of the possibilities of expressing their position, recognizing the need for joint actions in collecting critical information and exercising control over the implementation of decisions, the presence of some partnership in the interaction of authorities with the public. …”
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Searching for string bosenovas with gravitational wave detectors by Dawid Brzeminski, Anson Hook, Junwu Huang, Clayton Ristow

“…During the superradiance growth of a dark photon cloud — which occurs for dark photon masses m A ′ ~ 10 − 14 − 10 − 11 eV $$ {m}_{A^{\prime }}\sim {10}^{-14}-{10}^{-11}\textrm{eV} $$ around stellar-mass black holes ( m A ′ ~ 10 − 23 − 10 − 16 eV $$ {m}_{A^{\prime }}\sim {10}^{-23}-{10}^{-16}\textrm{eV} $$ for supermassive black holes) — the dark electromagnetic field might reach a critical field strength, when a network of dark photon strings is produced via a superheated phase transition. …”
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We Are on the Verge of Breakthrough Cures for Type 1 Diabetes, but Who Are the 2 Million Americans Who Have It? by Rebecca Smith, Samara Eisenberg, Aaron Turner-Phifer, Jacqueline LeGrand, Sarah Pincus, Yousra Omer, Fei Wang, Bruce Pyenson

“…**Conclusions:** Accurate projections of T1DM population growth are critical to ensure appropriate healthcare coverage and reimbursement for treatments. …”
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Identification of m6A methyltransferase-related WTAP and ZC3H13 predicts immune infiltrates in glioblastoma by Liyun Gao, Jiaxin Gao, Jiayin He, Wenyan Fan, Xiangxin Che, Xin Wang, Tao Wang, Chunhua Han

“…N6-methyladenosine (m6A) modification plays a critical role in the development of brain tumor. WTAP and ZC3H13 have been identified across various species. …”
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Insulin autoimmune syndrome in a 3-year-old boy: the youngest to date in China and a narrow review by Ming Cheng, Yuan Ding, Dongmei Wang, Chunxiu Gong

“…Elevated levels of IAAs and an inappropriate insulin to C-peptide molar ratio during an extended OGTT are critical indicators. Clinical Trial Number Not applicable.…”
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Complex immunotoxic effects of T-2 Toxin on the murine spleen and thymus: Oxidative damage, inflammasomes, apoptosis, and immunosuppression by Mingyan Chen, Yanfang Zhang, Yangbo Zhao, Kewei Cao, Ruiyan Niu, Dongguang Guo, Zilong Sun

“…These findings reveal critical pathways through which T-2 impairs immune system functionality and provide a basis for developing targeted therapeutic strategies to mitigate its immunotoxic effects.…”
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Deciphering the regulatory programs of RNA binding proteins in rheumatoid arthritis through single-cell transcriptome analysis by Hongbin Luo, Qunya Zheng, Youzheng Zhou, Weipeng Lai, Nanwen Zhang, Peng Chen

“…Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of RNA-binding proteins (RBPs), which are critical for alternative mRNA splicing and translational control in rheumatoid arthritis (RA). …”
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Corrosion Mitigation with Chemical Injection in Welded Carbon Steel Pipe for Offshore Water Treatment Plant by Henry Ekene Mgbemere, Johnson Olumuyiwa Agunsoye, Kenechi Ijeoma Ojemeni, Obianuju Vivian Izuegbu

“…This research has the potential to significantly impact offshore water treatment, providing valuable insights into the challenges and potential solutions for corrosion mitigation in this critical area. …”
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Enhancing technological sustainability in academia: leveraging ChatGPT for teaching, learning and evaluation by Labaran Isiaku, Abubakar Sadiq Muhammad, Hyelda Ibrahim Kefas, Fitzgerald Chidozie Ukaegbu

“…Findings – The study indicates that ChatGPT can have a significant impact on personalized learning, lesson planning, providing feedback, creating study materials, generating quizzes and exam questions, supporting language learning, offering virtual teaching assistance, tutoring and fostering critical thinking. However, it also sheds light on the ethical issues and challenges associated with its use, including privacy and data protection, transparency and alignment with educational principles. …”
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Efficacy and safety of non-pharmacological interventions for neonatal pain: an overview of systematic reviews by Xufei Luo, Qiao Shen, Zixuan Huang, Hongyao Leng, Xianlan Zheng

“…Based on AMSTAR 2, seven reviews were found to be of ‘high quality‘, eight of ‘moderate quality’, five of ‘low quality’ and nine of ‘critically low quality’. The GRADE results suggested that facilitated tucking, kangaroo care, sweet solutions, familiar odour or combined non-pharmacological interventions, such as a combination of sucrose and non-nutritive sucking, were effective and safe in reducing pain from medical procedures in neonates. …”
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“The Founder and Father of his Empire”: Voltaire on the Peace of Nystad and the Imperial Status of Russia by S. A. Mezin

“…According to Voltaire, the specific feature of the Russian Empire, created by Peter I, lies in the fact that it was a self-civilizing empire, bringing enlightenment on the neighboring «barbaric» peoples.The author of the paper, reviewing specific cases, arrives at a conclusion, that Voltaire’s works of high confidence for their time took a worthy standing in the world historiography of the Petrine era, due to a wide range of sources, the historian’s ability for their critical assessment, his seeking to maintain a certain evaluation independence in the description of events from different perspectives, his commitment to historical truth, his talent of a writer.The work is carried out within the project, aimed at publishing a first complete scientific edition of «The History of the Russian Empire under Peter the Great» in Russian.…”
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