Beyond COVID-19, the case for collecting, analysing and using sex-disaggregated data and gendered data to inform outbreak response: a scoping review by Simone E Carter, Shirin Heidari, Leah Zilversmit Pao, Marie-Amelie Degail, Marie Meudec, McKinzie Gales, Emelie Love Yonally Phillips, Christine Dubray, Clara Rodriguez Ribas Elizalde, M Ruby Siddiqui

“…Introduction Understanding sex and gender differences during outbreaks is critical to delivering an effective response. Although recommendations and minimum requirements exist, the incorporation of sex-disaggregated data and gender analysis into outbreak analytics and response for informed decision-making remains infrequent. …”
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APAH: An autonomous IoT driven real-time monitoring system for Industrial wastewater by Nishant Chavhan, Resham Bhattad, Suyash Khot, Shubham Patil, Aditya Pawar, Tejasvi Pawar, Palomi Gawli

“…APAH integrates multi-parameter sensors to continuously monitor critical water quality parameters such as pH, dissolved oxygen (DO), electrical conductivity (EC), total dissolved solids (TDS), turbidity, and temperature. …”
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Unveiling the novel role of circadian rhythms in sepsis and septic shock: unexplored implications for chronotherapy by Stewart D. Ramsay, Stewart D. Ramsay, Stewart D. Ramsay, Marni A. Nenke, Marni A. Nenke, Emily J. Meyer, Emily J. Meyer, David J. Torpy, David J. Torpy, Richard L. Young, Richard L. Young, Richard L. Young, Richard L. Young

“…Circadian rhythms are critical to coordinating body processes to external environmental cues, such as light and feeding, to ensure efficiency and maintain optimal health. …”
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Knowledge, attitudes, motivations and expectations regarding antimicrobial use among community members seeking care at the primary healthcare level: a scoping review protocol by Stephen M Campbell, Brian Godman, Eunice Bolanle Turawa, Nishana Ramdas, Johanna C Meyer, Natalie Schellack

“…The Covidence web-based platform will be used for literature screening and data extraction and the Critical Appraisal Skills Programme qualitative checklist will assess the quality of qualitative papers. …”
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Relationship between Ca2+ and cAMP as second messengers in ACTH-induced cortisol production in bovine adrenal fasciculata cells by Masahiko Kutsukake, Naoko Kuwabara, Yoshikazu Miyate, Kenzo Kudo, Shoko Goto, Eiichi Taira, Eiichi Tachikawa

“…These results strongly suggest that Ca2+, as a second messenger, is more critical than cAMP for cortisol production. However, both second messengers jointly participate in the production in adrenal fasciculata cells stimulated by ACTH.…”
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Modelling relative richness of flooding-response groups to predict hydrology-driven change in wetland plant communities by David C. Deane, Michelle T. Casanova, Jason Nicol, Justin D. Brookes

“…However, predictions against terrestrial species were reasonable (Cohen’s kappa > 0.58), suggesting the approach can identify hydrological tipping points associated with wetland drying. Modelling critical hydrology-driven transitions between wetland and terrestrial plants will require data on shallow sub-surface saturation (e.g., within ∼30 cm) rather than inundation depth.…”
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A real-world Pharmacovigilance study of brodalumab based on the FDA adverse event reporting system by Ke He, Kaidi Zhao, Tingyi Yin, Meng Liu, Jiashu Liu, Wenqian Du, Xinyi Liu, Baochen Cheng, Dewu Zhang, Yan Zheng

“…Moreover, this analysis highlighted the critical need for vigilant monitoring of adverse events, especially during the first month following the initiation of treatment. …”
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Expression Analysis and Functional Validation of DcTPSb1 in Terpene Synthesis of <i>Dendrobium chrysotoxum</i> by Yuxuan Jin, Shuting Zhou, Zhihui Du, Weize Wang, Zhilin Chen

“…Terpenes are critical components of the floral fragrance component in <i>Dendrobium chrysotoxum</i>, synthesized by terpene synthase (TPS). …”
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Rebound Mechanism and Control of the Hard Main Roof in the Deep Mining Roadway in Huainan Mining Area by Denghong Chen, Chao Li, Xinzhu Hua, Xiaoyu Lu, Yongqiang Yuan, Chen Li

“…Taking the occurrence conditions of the hard main roof in the deep 13-1 coal mining roadway in Huainan mining area as the research object, based on the mechanical parameters of the surrounding rock and the stress state of the main roof obtained by numerical simulation, a simply supported beam calculation model was established based on the damage factor D, main roof support reaction RA, RB, and critical range C (9 m) and B (7 m) at the elastoplastic junction of the solid coal side and mining face side (hereinafter referred to as “junction”). …”
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Mechanistic insights into Rho/MRTF inhibition-induced apoptotic events and prevention of drug resistance in melanoma: implications for the involvement of pirin by Bardees M. Foda, Bardees M. Foda, Annika E. Baker, Annika E. Baker, Annika E. Baker, Łukasz Joachimiak, Marzena Mazur, Richard R. Neubig, Richard R. Neubig, Richard R. Neubig

“…AimOvercoming therapy resistance is critical for effective melanoma control. Upregulation of Rho/MRTF signaling in human and mouse melanomas causes resistance to targeted therapies. …”
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Assessment of ecological environment quality and their drivers in urban agglomeration based on a novel remote sensing ecological index by Fangyuan Lu, Chen Zhang, Haoyu Cao, Xibin Wang, Tong Zheng, Zhenfang Huang

“…Balancing urban growth with ecological sustainability is a critical issue requiring immediate attention. This study utilizes the Google Earth Engine (GEE) platform, integrates MODIS imagery and NPP-VIIRS data to develop a Novel Remote Sensing Ecological Index (NRSEI). …”
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Nomenclatural issues concerning cultured yeasts and other fungi: why it is important to avoid unneeded name changes by Andrey Yurkov, Artur Alves, Feng-Yan Bai, Kyria Boundy-Mills, Pietro Buzzini, Neža Čadež, Gianluigi Cardinali, Serge Casaregola, Vishnu Chaturvedi, Valérie Collin, Jack W. Fell, Victoria Girard, Marizeth Groenewald, Ferry Hagen, Chris Todd Hittinger, Aleksey V. Kachalkin, Markus Kostrzewa, Vassili Kouvelis, Diego Libkind, Xinzhan Liu, Thomas Maier, Wieland Meyer, Gábor Péter, Marcin Piątek, Vincent Robert, Carlos A. Rosa, Jose Paulo Sampaio, Matthias Sipiczki, Marc Stadler, Takashi Sugita, Junta Sugiyama, Hiroshi Takagi, Masako Takashima, Benedetta Turchetti, Qi-Ming Wang, Teun Boekhout

“…ABSTRACT The unambiguous application of fungal names is important to communicate scientific findings. Names are critical for (clinical) diagnostics, legal compliance, and regulatory controls, such as biosafety, food security, quarantine regulations, and industrial applications. …”
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Maintenance of Genetic Diversity Despite Population Fluctuations in the Lesser Prairie‐Chicken (Tympanuchus pallidicinctus) by Andrew J. Lawrence, Scott A. Carleton, Sara J. Oyler‐McCance, Randy W. DeYoung, Clay T. Nichols, Timothy F. Wright

“…ABSTRACT Assessments of genetic diversity, structure, history, and effective population size (Ne) are critical for the conservation of imperiled populations. …”
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Bacteria-Inspired Synthesis of Silver-Doped Zinc Oxide Nanocomposites: A Novel Synergistic Approach in Controlling Biofilm and Quorum-Sensing-Regulated Virulence Factors in <i>Pseu... by Abirami Karthikeyan, Manoj Kumar Thirugnanasambantham, Fazlurrahman Khan, Arun Kumar Mani

“…Multidrug-resistant <i>Pseudomonas aeruginosa</i> infections pose a critical challenge to healthcare systems, particularly in nosocomial settings. …”
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Accurate Spatial Heterogeneity Dissection and Gene Regulation Interpretation for Spatial Transcriptomics using Dual Graph Contrastive Learning by Zhuohan Yu, Yuning Yang, Xingjian Chen, Ka‐Chun Wong, Zhaolei Zhang, Yuming Zhao, Xiangtao Li

“…Here, stDCL is developed, a dual graph contrastive learning method to identify spatial domains and interpret gene regulation in spatial transcriptomics data. stDCL adaptively incorporates gene expression data and spatial information via a graph embedding autoencoder, thereby preserving critical information within the latent embedding representations. …”
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Phenotypic Profiling of Selected Cellulolytic Strains to Develop a Crop Residue-Decomposing Bacterial Consortium by Arman Shamshitov, Egidija Satkevičiūtė, Francesca Decorosi, Carlo Viti, Skaidrė Supronienė

“…Overall, these findings underscore the critical role of metabolic profiling in gaining a deeper understanding of microbial capabilities and addressing the complexities of residue composition and environmental variability.…”
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Effects of community family doctors-led intervention for self-management and medication adherence in type 2 diabetes mellitus patients: study protocol of a cluster randomised contr... by Yue Chen, Biqi Ren, Ningsheng Wang, Shuang Lei, Shuzhi Lin, Lianye Liu, Yufang Xiang, Bianling Feng

“…Introduction The management of diabetes has become a critical public health issue in China. The development of community-based type 2 diabetes management in China has not yet reached an ideal state, and the most suitable management methods for diabetic patients are still being explored. …”
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Adapting to change: exploring the distribution dynamics of the alien and potentially invasive aphid species Cinara curvipes (Hemiptera: Aphididae) in the context of global warming by K. Wieczorek, A. Bugaj-Nawrocka, B. Borowiak-Sobkowiak, A. Endrestøl, H. P. Ravn, W. Solarz, R. Durak

“…Its high reproductive output allows the species to quickly colonise new habitats and exploit available resources, contributing to its potential invasiveness. We emphasise the critical need for collaborative engagement among researchers, stakeholders, and the public to bolster citizen science initiatives and reinforce environmental monitoring networks, all within the framework of an early detection and rapid response (EDRR) process. …”
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Studying the Humoral Response against SARS-CoV-2 in Cuban COVID-19 Recovered Patients by Ivette Orosa Vázquez, Marianniz Díaz, Yaima Zúñiga Rosales, Klayris Amada, Janoi Chang, Ernesto Relova Hernández, Yaima Tundidor, Hilda Roblejo Balbuena, Giselle Monzón, Bárbara Torres Rives, Enrique Noa Romero, Danay Carrillo Valdés, Irinia Valdivia Álvarez, Aurora Delahanty Fernández, Claudia Díaz, Joaquín Solozabal, Mileidys Gil, Belinda Sánchez, Gertrudis Rojas, Beatriz Marcheco, Tania Carmenate

“…Understanding the immune response generated by SARS-CoV-2 is critical for assessing efficient therapeutic protocols and gaining insights into the durability of protective immunity. …”
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Bidirectional Mendelian Randomization Analysis of the Association Between Mitochondrial Proteins and Neurodegenerative Diseases by Fangyuan Wang, Zhou Jing, Qingyi Wang, Minghe Li, Bingqi Lu, Ao Huo, Chenglin Zhao, Huanyu Zhou, Wulong Liang, Weihua Hu, Xudong Fu

“…These findings underscore the pivotal role of mitochondrial proteins in neurodegenerative diseases, offering critical insights into disease mechanisms and potential therapeutic avenues.…”
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