Case report of the first use of a hydrogel rectal spacer for prostate cancer reirradiation via LDR brachytherapy: applications and technical notes by Amina Lazrek, Sebastiano Finocchi Ghersi, Adeline Petre, Sarah Houabes, Anne-Agathe Serre, Frederic Gassa, Magali Sandt, Cecile Laude, Camille Roukoz, Salvatore Cozzi

“…This article examines the critical role of a biodegradable hydrogel spacer, which creates a temporary interspace between the prostate and the rectum, thus reducing radiation exposure to healthy tissues.Case descriptionWe present a case of a man with a history of intermediate-risk prostate adenocarcinoma initially treated with external beam radiotherapy in 2015. …”
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The influence of childhood trauma on social media-induced secondary traumatic stress among college students: the chain mediating effect of self-compassion and resilience by Xiqin Liu, Ye Yao, Siyu Zhu, Qiyong Gong

“…Background: Studies have shown that media exposure to critical public events can lead to secondary traumatic stress (STS). …”
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Transcriptome Analysis and Phytohormone Profile Reveal Core Phytohormone Regulating Parthenocarpy in Fingered Citron by Qianbin Chen, Jinjian Xu, Xinjian Zou, Yanjun Zhang, Xiaoxian Zhu, Kewei Zhang, Wenrong Chen, Fanglei Liao, Weidong Guo

“…Our findings highlight the central regulatory role of auxin in parthenocarpy in fingered citron, with ABA acting as a critical modulator. The suppression of ABA alone disrupts parthenocarpy despite stable auxin levels, emphasizing the necessity of balanced hormone interactions. …”
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Transition from pediatric to adult health services: A survey of challenges, needs, and preferences of youths and parents by Eric Racine, François Ouimet, Rocio Gissel Gutierrez Rojas, Marie-José Clermont, Anne Fournier

“…Aim: Transition from pediatric to adult healthcare is a critical period. Recommendations have pointed to greater preparation of youths and families and better coordination. …”
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Association between individual occupational noise exposure and overweight/obesity among automotive manufacturing workers in South China by Jiaheng Yu, Jiaxin CUI, Haijuan Huang, Jingwen Zhang, Xin Li, Yanmei Ruan, Zejin Ou, Zhi Wang

“…Additionally, shift and night work were identified as critical moderating factors, with a stronger association observed among workers engaged in shift and night work. …”
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Boosting Cyberattack Detection Using Binary Metaheuristics With Deep Learning on Cyber-Physical System Environment by Alanoud Al Mazroa, Fahad R. Albogamy, Mohamad Khairi Ishak, Samih M. Mostafa

“…The swift advancement of cyber-physical systems (CPSs) across sectors such as healthcare, transportation, critical infrastructure, and energy enhances the crucial requirement for robust cybersecurity measures to protect these systems from cyberattacks. …”
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Personal Identification Using Embedded Raspberry Pi-Based Face Recognition Systems by Sebastian Pecolt, Andrzej Błażejewski, Tomasz Królikowski, Igor Maciejewski, Kacper Gierula, Sebastian Glowinski

“…Verification involved selecting the similarity threshold, a critical factor influencing the balance between accuracy, security, and user experience in biometric systems. …”
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Switching to biological DMARDs versus cycling among JAK inhibitors in patients with rheumatoid arthritis and with inadequate response to JAK inhibitors: from FIRST registry by Yoshiya Tanaka, Hiroaki Tanaka, Satoshi Kubo, Shingo Nakayamada, Yusuke Miyazaki, Yoshino Inoue, Shunsuke Fukuyo, Ippei Miyagawa, Kentaro Hanami, Yasuyuki Todoroki, Masanobu Ueno, Yurie Satoh-Kanda, Ayako Yamaguchi

“…Multiple logistic regression in this group identified another JAKi cycle as the critical factor for the treatment response.Conclusions Cycling JAKis is more effective than switching to bDMARDs in JAKi-IR RA, with no differences in safety or retention. …”
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Influence of binge drinking on the resting state functional connectivity of university Students: A follow-up study by Samuel Suárez-Suárez, Fernando Cadaveira, Alfonso Barrós-Loscertales, José Manuel Pérez-García, Socorro Rodríguez Holguín, Javier Blanco-Ramos, Sonia Doallo

“…Maintaining a BD pattern during critical neurodevelopmental years impacts RS-FC, indicating mid-to-long-term alterations in functional brain organization. …”
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Identification of <i>Tinomiscium petiolare</i> from Vietnam using the DNA barcode by B. B. Thinh, R. V. Doudkin, L. D. Chac, H. V. Chinh, Q. V. Hoi, N. T. Lien

“…Precise and rapid identification of T. petiolare is critical and essential for the classification, propagation, use and conservation of its genetic resources. …”
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Transient dynamic analysis of cutter-head loads: effects of different cutter spacings during excavation by Minglei Kang, Haining Liu, Wenjia Ma, Luqi Wang, Jianjun Zhou, Miao Li

“…As a critical component in achieving the rock-breaking function during the operation of Tunnel Boring Machines (TBM), the cutterhead inevitably generates significant vibrations during the rock-breaking process. …”
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Luteolin Attenuates IL-1β-Induced THP-1 Adhesion to ARPE-19 Cells via Suppression of NF-κB and MAPK Pathways by Wen-Chung Huang, Chian-Jiun Liou, Szu-Chuan Shen, Sindy Hu, Chien-Yu Hsiao, Shu-Ju Wu

“…Cytokine-induced endothelial dysfunction leads to inflammation and vascular adhesion molecule production in retinal pigment epithelium (RPE) cells. Inflammation is a critical mediator in retinal degeneration (RD) diseases, including age-related macular degeneration (AMD), and RD progression may be prevented through anti-inflammatory activity in RPE cells. …”
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TEACHERS’ AND STUDENTS’ ATTITUDES TOWARDS THE USE OF ARTIFICIAL INTELLIGENCE: ALL-UKRAINIAN RESEARCH by Stanislav Dovgyi, Svitlana Babiichuk, Lidiia Davybida, Mariia Biletska

“…Understanding the essential role of teachers and students as active participants in this transformation, as well as the factors influencing their perceptions and attitudes toward AI, is critical. In Ukraine, the emergence and rapid spread of accessible AI tools occurred during a time of full-scale military conflict, bringing about drastic disruptions to traditional educational processes. …”
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The Ability of Combined Flavonol and Trihydroxyorganic Acid to Suppress SARS-CoV-2 Reproduction by Andrey Bogoyavlenskiy, Pavel Alexyuk, Madina Alexyuk, Vladimir Berezin, Irina Zaitseva, Elmira Omirtaeva, Adolat Manakbayeva, Yergali Moldakhanov, Elmira Anarkulova, Anar Imangazy, Kuralay Akanova, Zhumagali Koshemetov, Nurkul Orazymbetova, Bakyt Umuraliyev

“…The global burden of COVID-19 continues to rise, and despite significant progress in vaccine development, there remains a critical need for effective treatments for the severe inflammation and acute lung injury associated with SARS-CoV-2 infection. …”
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Plant Growth and Nutritional Quality Attributes of Basella alba Applied with Variable Rates of Nitrogen Fertilizer at Different Planting Dates under Canadian Maritime Climatic Cond... by Nishchitha Hemmige Natesh, Mercy O. Ijenyo, Samuel Kwaku Asiedu, H. P. Vasantha Rupasinghe, Lord Abbey

“…Nitrogen (N) fertilization at critical planting time is important to optimize productivity and reduce nitrate accumulation in edible portions of green leafy vegetable plants. …”
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Interest, uptake, and feasibility trial of a real-life digital health intervention to improve lifestyle in Brazil by Raquel B De Boni, Jurema C Mota, Michael Duncan, Leonardo Linconl, Giovanna Lucieri Alonso Costa, Sofia Pimentel, Kamila P Sales, Fabiana Gaspar, Fernanda Adaes, Felipe B Schuch, Vicent Balanzá-Martinez, Flavio Kapczinski, Renato S Lima

“…Addressing digital access, literacy inequities, and strengthening regulations are critical for the future success and equity of DHIs in public health systems. …”
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The Identification and Validation of a Robust Immune-Associated Gene Signature in Cutaneous Melanoma by Le-Bin Song, Jiao-Chen Luan, Qi-Jie Zhang, Lin Chen, Hao-Yang Wang, Xue-Chen Cao, Ning-Hong Song, Yan Lu

“…Our study demonstrated that the six IAG signature played a critical role in the prognosis and immunotherapy of melanoma, which might help clinicians predict patients’ survival and provide individualized treatment.…”
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The Impact of Amniotic Fluid Interleukin-6, Interleukin-8, and Metalloproteinase-9 on Preterm Labor: A Narrative Review by Theodoros Karampitsakos, Despoina Mavrogianni, Nikolaos Machairiotis, Anastasios Potiris, Periklis Panagopoulos, Sofoklis Stavros, Panos Antsaklis, Peter Drakakis

“…The identification of reliable biomarkers for early prediction is critical for improving maternal, fetal, and neonatal outcomes. …”
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Systematic identification of the chemical components of leaves and roots of Didymocarpus heucherifolius Hand.-Mazz. based on UHPLC Q-Exactive Orbitrap MS technology coupled with mo... by Liangyin Shu, Shunli Xiao, Kailin Li, Huibin Luo, Meng Li, Qingrui Yang, Bowen Gao, Jiaxin Li, Fang Yan, Wei Cai

“…Therefore, a rapid and accurate identification and quantification are critical in phytochemical analysis. An efficient approach based on molecular networking strategy coupled with ultra high-performance liquid chromatography coupled with Q-Exactive Orbitrap tandem mass spectrometry (UHPLC Q-Exactive Orbitrap MS) was used to analyze the chemical components systematically. …”
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Heterogeneity of cancer-associated fibroblast subpopulations in prostate cancer: Implications for prognosis and immunotherapy by Chen Ding, Jiange Wang, Jie Wang, Jiqiang Niu, Zhikai Xiahou, Zhou Sun, Zhenzhen Zhao, Dongyang Zeng

“…Conclusion: This investigation illuminates the critical potential of targeting CAFs to augment immunotherapeutic approaches in prostate cancer. …”
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