Impact of Nano-Fuel Additives and Nano-Lubricant Oil Additives on Diesel Engine Performance and Emission Characteristics by Dipakkumar Chimangiri Gosai, Ashishkumar Jashvantlal Modi, Anil Kumar Gillawat

“…Fuel saving and emission control in transportation is a global critical issue, so research is required to concentrate on the energy conservation of diesel engines. …”
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VCP downstream metabolite glycerol-3-phosphate (G3P) inhibits CD8+T cells function in the HCC microenvironment by Cheng Cheng, Qingrui Zha, Linmao Sun, Tianming Cui, Xinyu Guo, Changjian Xing, Zhengxiang Chen, Changyong Ji, Shuhang Liang, Shengwei Tao, Junhui Chu, Chenghui Wu, Qi Chu, Xuetian Gu, Ning Zhang, Yumin Fu, Shumin Deng, Yitong Zhu, Jiabei Wang, Yao Liu, Lianxin Liu

“…The accumulated G3P diffuses into the TME and directly interacts with SRC-family tyrosine kinase LCK, a critical component of the T-cell receptor (TCR) signaling pathway in CD8+T cells. …”
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Body donor reperfusion and re-ventilation in medical training: an Italian study testing SimLife® by Irene Neri, Giulio Vara, Antonietta Fazio, Maria Vittoria Marvi, Foteini-Dionysia Koufi, Elisa Boschetti, Simone Lodi, Giulia Adalgisa Mariani, Marilisa Quaranta, Anna Maria Billi, Alessandra Ruggeri, Carlo Barausse, Cyril Brèque, Annalisa Plava, Veronica Moretti, Lucia Manzoli, Stefano Ratti

“…Post-simulation, structured interviews were used to collect data on the interventions performed, participant perceptions of the technology’s usefulness, enjoyment, and willingness to repeat the experience, as well as critical issues encountered.ResultsKey findings include that 86% of participants rated SimLife® technology as extremely useful for post-lauream training, while 84% found it highly beneficial for team-building activities. …”
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The Role of Additional K-Wires on AO Type C Distal Radius Fracture Treatment with External Fixator in Young Population by Ivan Micic, Erica Kholinne, Yucheng Sun, Jae-Man Kwak, In-Ho Jeon

“…Some surgeons suggested that additional K-wires may play a critical role in the outcome. The purpose of study is to evaluate the role of additional K wires in treating distal radial fracture with external fixator regarding its outcome. …”
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EMC2 suppresses ferroptosis via regulating TFRC in nasopharyngeal carcinoma by Xianghui Chen, Xiaoyan Wang, Yuxia Zou, Yan Wang, Tingting Duan, Zijie Zhou, Yi Huang, Qing Ye

“…Mechanistically, we identified transferrin receptor (TFRC) as a critical downstream protein. EMC2 interacted with TFRC and promoted its ubiquitin-proteasomal degradation. …”
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Synergistic impact of temperature and pore saturation on corrosion in carbonated reinforced concrete by Li Soon Wan, Mayuko Hirata, Toshinori Oyamoto, Tetsushi Kanda, Kang Hai Tan

“…This study investigates the temperature-pore saturation relationship through systematic experimental variation (0–40 °C, 60–100 % pore saturation) using electrochemical and non-destructive measurements, aiming to develop accurate predictive tools for RC maintenance in tropical climates. Results revealed a critical phenomenon: minimum pore saturation threshold for severe corrosion decreases significantly with increasing temperature. …”
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The Gut Microbiota-Related Antihyperglycemic Effect of Metformin by Izabela Szymczak-Pajor, Józef Drzewoski, Małgorzata Kozłowska, Jan Krekora, Agnieszka Śliwińska

“…It is critical to sustain the diversity of the microbiota to maintain host homeostasis and health. …”
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Evaluating different drought products for assessing drought and implications on agriculture in Nepal by Shishir Chaulagain, Manoj Lamichhane, Urusha Chaulagain, Sushant Gyawali, Sadina Shrestha, Vishnu Prasad Pandey

“…These insights can inform targeted interventions for winter wheat during their critical growth periods to mitigate drought effects in agriculture.…”
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Unveiling Genital Tuberculosis: India’s hidden Infertility Epidemic by Yashvanthan VR, Angeline Grace G, Sujitha P, Ilam Ilaval T, Hariharan S

“…It also highlights diagnostic and management challenges while proposing strategies to address this critical public health issue. GTB contributes to 15-20% of infertility cases in India, with the highest burden among women aged 20-40 years. …”
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Exploring offshore wind’s potential to enhance energy security in nations with limited land and fuel resources by Kenji Shiraishi, Umed Paliwal, Nikit Abhyankar, Daniel M Kammen, Amol Phadke, Won Young Park

“…Offshore wind (OSW) power is critical to addressing energy security issues in nations with limited land and fuel resources. …”
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Complementary Non‐invasive Fish Monitoring Distinguishes Depth‐Dependent Fish Communities by Ewan Burns, Vijini Mallawaarachchi, Thomas M. Clarke, Belinda Martin, Joseph D. DiBattista, Jamie Hicks, Danny Brock, Elizabeth A. Dinsdale, Charlie Huveneers, Michael P. Doane

“…ABSTRACT Human activities are increasingly affecting marine environments, with fish communities serving as critical indicators of ecosystem health. Effective management of marine fishes is imperative for maintaining the balance of marine ecosystems, necessitating comprehensive monitoring strategies. …”
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The SIRT5-JIP4 interaction promotes osteoclastogenesis by modulating RANKL-induced signaling transduction by Kecheng Zhu, Chunxiang Sheng, Linlin Zhang, Yuying Yang, Xiaojing Chen, Tao Jiang, Jiaxi Song, Deng Zhang, Xiao Wang, Hongyan Zhao, Lihao Sun, Libin Zhou, Bei Tao, Jianmin Liu

“…In the cytoplasm, SIRT5 interacted with the scaffold protein JNK-interacting protein 4 (JIP4) to finely regulate MAPK signaling, which was critical for osteoclast differentiation and activation. …”
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Equipping our public health nutrition workforce to promote planetary health: a case example of tertiary education co-designed with students by Ka Po Chau, Wing Chong, Raquel Londono, Beau Cubillo, Julia McCartan, Liza Barbour

“…Students prioritised the values of ‘collaboration’ and ‘respect’ as being critical to guide personal and professional practice to promote planetary health. …”
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An electrolyte-gated transistor for the monitoring of a CRISPR/Cas activity by Pierre Guermonprez, Le Tu Anh, Louis Renaud, Pierre Nioche, Eric Krejci, Aurélie Alleaume-Butaux, Nicolas Battaglini, Vu Thi Thu, Sébastien Sanaur, Benoît Piro

“…Detection of Ribonucleic acids (RNA) is a critical step in the identification of viral or bacterial infections in humans and animals. …”
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A 10-Year Risk Assessment and Primary Prevention Study of Atherosclerotic Cardiovascular Disease Among Adult Patients in Saudi Arabia: A Cross-Sectional Study by Abdulhameed Alkhalaf, Qasem Aljabr, Khalid Al Mulla, Duaa Almubarak, Abdul Sattar Khan, Zainab Y. Al Jaziri, Ibrahim Albahrani

“…Modifiable risk factors, including smoking, diabetes, and hypertension, combined with statin and aspirin adherence, highlight critical areas for targeted interventions to reduce the ASCVD burden in this population.…”
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Polymorphism of microsattelite loci within the grape germplasm collection maintained at the Dagestan Experiment Station of VIR by M. M. Agakhanov, V. A. Volkov, P. S. Ulianich, K. M. Abdullaev, E. N. Kislin

“…As for any other large germplasm collections, the problem of genetic identification of the accessions and their originality is critical for the ampelographical collection. Genome of Vitis vinifera L. contains many polymorphic microsatellite loci, their allele diversity could be used to reveal the genetic structure of the ex situ collection as well as for the identification of duplicates. …”
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Life Cycle Assessment of Methanol Production from Municipal Solid Waste: Environmental Comparison with Landfilling and Incineration by Cristiano Queiroz Cerqueira, Electo Eduardo Silva Lora, Lidiane La Picirelli de Souza, Márcio Montagnana Vicente Leme, Regina Mambeli Barros, Osvaldo José Venturini

“…In response, this study addresses a critical question: is methanol production from MSW, a waste-to-chemical (WtC) alternative based on circular economy principles, a more environmentally sustainable approach compared to traditional waste-to-energy (WtE) methods like landfilling with biogas recovery and incineration? …”
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Liquid chromatography-high resolution mass spectrometry based analysis of persistent mobile organic compounds in aqueous samples: Method development and optimization by Kyriaki Anagnostopoulou, Vasileios Alampanos, Eleni Evgenidou, Dimitra A. Lambropoulou

“…Persistent Mobile Organic Compounds (PMOCs) represent a critical threat to water resources due to their high solubility, resistance to degradation, and potential toxicity, posing risks to human health and ecosystems. …”
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Modification of Gene Expression Involved in Alkaloid Production in Opium Poppy by VIGS Combined With Pretreatment of Macerozyme Enzyme by Deniz Ece Özcan, Deniz Köm, Ozan Doğan, Semiha Erişen, Selma Onarici

“…This study highlights the critical role of macerozyme enzymatic pretreatment in overcoming cell wall barriers, enabling effective VIGS applications in somatic suspension cultures. …”
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Adolescent girls’ explanations of high rates of low mood and anxiety in their population: a co-produced qualitative study by Ola Demkowicz, Rebecca Jefferson, Pratyasha Nanda, Lucy Foulkes, Jo Lam, Steven Pryjmachuk, Rhiannon Evans, Bernadka Dubicka, Liz Neill, Laura Anne Winter, Georgina Nnamani

“…Conclusions The study offers a critically important contribution to evidence on gendered inequalities in low mood and anxiety, drawing attention to the interwoven and complex nature of girls’ lives and illuminating various aspects that would benefit from greater research. …”
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