RAS, a Pentatricopeptide Repeat Protein, Interacts with OsTRX z to Regulate Chloroplast Gene Transcription and RNA Processing by Zhennan Qiu, Shiyong Wen, Peinan Sun, Dongdong Chen, Chunmiao Wang, Xiliang Song, Liying Xiao, Peiliang Zhang, Dongying Zhao, Cuiping Wen, Peiyan Guan, Xuechu Du, Yinghui Sun, Chenshan Xu, Jian Song

“…Collectively, our findings highlight the critical role of RAS in chloroplast development, as it is involved in RNA processing and the regulation of chloroplast gene expression.…”
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NF-κB/AP-1-Targeted Inhibition of Macrophage-Mediated Inflammatory Responses by Depigmenting Compound AP736 Derived from Natural 1,3-Diphenylpropane Skeleton by Van Thai Ha, Heung Soo Beak, Eunji Kim, Kwang-Soo Baek, Muhammad Jahangir Hossen, Woo Seok Yang, Yong Kim, Jun Ho Kim, Sungjae Yang, Jeong-Hwan Kim, Yung Hyup Joo, Chang Seok Lee, Joonho Choi, Hong-Ju Shin, Sungyoul Hong, Song Seok Shin, Jae Youl Cho

“…Since macrophage-mediated inflammatory responses are critical for skin health, here we investigated the potential anti-inflammatory activity of AP736. …”
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A LASSO-derived clinical score to predict severe acute kidney injury in the cardiac surgery recovery unit: a large retrospective cohort study using the MIMIC database by Qi Guo, Jingjing Huang, Yuewei Li, Hongwei Li, Jingfeng Wang, Yong Xie, Tucheng Huang, Wanbing He, Wenyu Lv, Jieping Huang, Yangxin Chen

“…Objectives We aimed to develop an effective tool for predicting severe acute kidney injury (AKI) in patients admitted to the cardiac surgery recovery unit (CSRU).Design A retrospective cohort study.Setting Data were extracted from the Medical Information Mart for Intensive Care (MIMIC)-III database, consisting of critically ill participants between 2001 and 2012 in the USA.Participants A total of 6271 patients admitted to the CSRU were enrolled from the MIMIC-III database.Primary and secondary outcome Stages 2–3 AKI.Result As identified by least absolute shrinkage and selection operator (LASSO) and logistic regression, risk factors for AKI included age, sex, weight, respiratory rate, systolic blood pressure, diastolic blood pressure, central venous pressure, urine output, partial pressure of oxygen, sedative use, furosemide use, atrial fibrillation, congestive heart failure and left heart catheterisation, all of which were used to establish a clinical score. …”
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Porto Alegre Line predicts lenticulostriate arteries encasement and extent of resection in insular gliomas. A preliminary study by Gustavo Rassier Isolan, Gustavo Rassier Isolan, Gustavo Rassier Isolan, Samir Ale Bark, Samir Ale Bark, Jander Moreira Monteiro, Jander Moreira Monteiro, Tobias A. Mattei, Kaan Yağmurlu, Rafaela Fernandes Gonçalves, Rafaela Fernandes Gonçalves, Osvaldo Malafaia, Rafael Roesler, Rafael Roesler, Rafael Roesler, Jurandir Marcondes Ribas Filho

“…The resection limit of tumors placed medially to the Porto Alegre line was intraoperative direct LSTa visualization.ResultsThe LSTa involvement was the most critical medial limiting factor in more aggressive tumor resection and an excellent overall survival (P = 0.022). …”
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OptiBench: An Optical Distance Measurement Test Bench Using Adaptive Algorithm With Sensor Fusion and Environmental Shielding by Kanchana Chathurangi Ahangama, Hemali Pasqual, Chinthaka Premachandra, H. Waruna Haripriya Premachandra

“…It is essential in systems where accuracy and reliability are critical. Environmental factors such as temperature fluctuations, humidity, and light intensity randomly affect the performance of ODM systems. …”
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Barriers and facilitators to data-based decision making in Australian early childhood education and care: A qualitative study by Shauna Sherker, Karen Villanueva, Ruth Beatson, Caitlin M. Macmillan, Wan Yi Lee, Olivia Hilton, Carly Molloy, Sharon Goldfeld

“…Early childhood education and care (ECEC) provides a critical platform for children's development in the early years. …”
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Retrieval of water quality parameters based on IOA-ML models and their response to short-term hydrometeorological factors by Wentong Hu, Donghao Miao, Chi Zhang, Zixian He, Wenquan Gu, Dongguo Shao

“…Study focus: Large-scale and high-precision estimation of water quality parameters (WQPs) is critical in explaining the spatiotemporal dynamics and clarifying their response to short-term hydrometeorological factors. …”
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Extreme precipitation associated with atmospheric rivers over West Antarctic ice shelves: insights from kilometre-scale regional climate modelling by E. Gilbert, D. Pishniak, J. A. Torres, A. Orr, M. Maclennan, M. Maclennan, N. Wever, K. Verro, K. Verro

“…Our work highlights that kilometre-scale models are useful tools to investigate the total precipitation amount and its partitioning into rain and snow over this globally important and climatically sensitive region, and it highlights the critical need for in situ observations of rainfall.…”
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Long-term forecasting of shield tunnel position and attitude deviation using the 1DCNN-informer method by Jiajie Zhen, Ming Huang, Shuang Li, Kai Xu, Qianghu Zhao

“…The cutterhead rotation speed, advance speed, and chamber pressure are of critical importance in the prediction of shield position and attitude deviation. …”
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Improving fluoroprobe sensor performance through machine learning by D. Lafer, A. Sukenik, T. Zohary, O. Tal

“…Accurate assessment of phytoplankton abundance and community structure is critical for understanding the health and functioning of lake ecosystems. …”
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Exploring chitin metabolite profiles and sensitivity differences in Collembola species exposed to teflubenzuron by Saúl Fernandes, Diana Ilyaskina, Matty P. Berg, Marja H. Lamoree, Pim E.G. Leonards, Cornelis A.M. van Gestel

“…The distinct metabolic responses among Collembola species to chitin synthesis inhibitors provide critical insights into their ecological resilience or vulnerability, enhancing our understanding of ecosystem dynamics and the potential ramifications of chemical exposure.…”
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Flow Cytometry of the Side Population: Tips & Tricks by Irene Sales-Pardo, Ariadna Avendaño, Vanessa Martinez-Muñoz, Marta García-Escarp, Raquel Celis, Phil Whittle, Jordi Barquinero, Joan Carles Domingo, Pedro Marin, Jordi Petriz

“…Results: The Ho342 concentration and the staining procedure are critical for the optimal resolution of the SP cells. …”
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Navigating urban poverty: The role of livelihood capital in the livelihood strategies of urban beggars in Indonesia by Choirul Amin, Wahyu Tyas Pramono, Jumadi Jumadi, Dewi Novita Sari, Maxim G.M. Samson

“…The global challenges of urban poverty and homelessness are widely considered among the most critical, with beggars usually symbolizing visible and marginalized groups of the urban poor. …”
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Mechanical Activation of cPLA2 Impedes Fatty Acid β‐Oxidation in Vein Grafts by Linwei Fan, Yuanjun Tang, Jian Liu, Yueqi Liu, Yiwei Xu, Jiayu Liu, Han Liu, Wei Pang, Yuxuan Guo, Weijuan Yao, Tao Zhang, Qin Peng, Jing Zhou

“…This study highlights the critical role of cytosolic Phospholipase A2 (cPLA2)/ Yin Yang 1 (YY1)/ carnitine palmitoyltransferase 1b (CPT1B) signaling in coordinating VSMC mechanical activation by inhibiting fatty acid β‐oxidation. …”
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Intraparenchymal Neural Stem/Progenitor Cell Transplantation for Ischemic Stroke Animals: A Meta-Analysis and Systematic Review by Hailong Huang, Kun Qian, Xiaohua Han, Xin Li, Yifeng Zheng, Zhishui Chen, Xiaolin Huang, Hong Chen

“…Intriguingly, endogenous apoptosis inhibition and axonal regeneration played the most critical role in intraparenchymal NSPC transplantation among the cellular mechanisms. …”
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Metabolomics Biomarkers in Prediction of Sudden Infant Death Syndrome: The Role of Short Chain Fatty Acids by Maria Aslam, Omer Riaz, Jawaria Aslam, Dost Muhammad Khan, Mustafa Hameed, Muhammad Suleman, Rizwan Shahid, Turke Althobaiti, Naeem Ramzan

“…These results underscore the potential of ML in the early assessment of SIDS risk, highlighting the critical role of SCFA and advancing the prospects for preventative healthcare.…”
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Effect of ON and OFF Axis Open Hole Tensile Testing of GFRP/Epoxy Composites by Sunith Babu Loganathan, Ashok Kumar Krishnappa, Jaya Christiyan Kumaravelu Grace Jesu Bai, Ritin Pavirala, Rajesh Mathivanan

“…Further, how these materials behave under tensile loads near these openings is critical for ensuring the safety and reliability of such structures. …”
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Comparative miRNAome combined with transcriptome and degradome analysis reveals a novel miRNA-mRNA regulatory network associated with starch metabolism affecting pre-harvest sprout... by Longqing Sun, Ting Zhao, Dandan Qin, Jing Dong, Daorong Zhang, Xifeng Ren

“…Then, the starch degradation pathway controlled by seven miRNA-RNA pairs were supposed to be the essential regulation center for seed germination in wheat, which also could play a critical role on the PHS resistance. Conclusion Our findings revealed the complex impact of the miRNA-mediated mechanism for forming intrinsic and inherent differences, which resulting in significant difference on PHS performance between white wheat varieties.…”
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Incremental Instance-Oriented 3D Semantic Mapping via RGB-D Cameras for Unknown Indoor Scene by Wei Li, Junhua Gu, Benwen Chen, Jungong Han

“…Although there are plenty of studies developing accurate object-level mapping systems with different types of cameras, these methods either process the instance segmentation problem in completed mapping or suffer from a critical real-time issue due to heavy computation processing required. …”
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STRENGTHS AND WEAKNESSES OF SMART TOURISM DESTINATIONS: A CROSS-GENERATIONAL STUDY by Elena BOTEZAT, Olimpia BAN, Adela Laura POPA, Dorin Cristian COITA, Teodora Mihaela TARCZA, Lidia CHIRICOI

“…This study was carried out to gain an understanding of the perceptions of Romanian tourists of the strengths and weaknesses of smart tourism destinations as the first part of any SWOT analysis designed to collect critical factors about the current situation aiming to improve it to remain on a highly competitive market. …”
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