The control of effective source rocks on the distribution of hydrocarbon reservoirs in a lacustrine rift-basin: insights from a 3D basin modeling study by Bang Zeng, Jianhua Qu, Zhongrong Mi, En Xie, Hui Fu, Sibo Yang, Yang Shi, Meijun Li

“…Effective source kitchens play a critical role in controlling hydrocarbon accumulation patterns, yet existing studies often rely on statistical methods limited by exploration biases. …”
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V-ATPase in glioma stem cells: a novel metabolic vulnerability by Alessandra Maria Storaci, Irene Bertolini, Cristina Martelli, Giorgia De Turris, Nadia Mansour, Mariacristina Crosti, Maria Rosaria De Filippo, Luisa Ottobrini, Luca Valenti, Elisa Polledri, Silvia Fustinoni, Manuela Caroli, Claudia Fanizzi, Silvano Bosari, Stefano Ferrero, Giorgia Zadra, Valentina Vaira

“…Conclusions V-ATPase activity in GSC is critical for mitochondrial metabolism and cell growth. …”
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A Review: Potential of Earth Observation (EO) for Mapping Small-Scale Agriculture and Cropping Systems in West Africa by Niklas Heiss, Jonas Meier, Ursula Gessner, Claudia Kuenzer

“…This sets the stage for future investigations aimed at addressing critical challenges in West African smallholder agricultural systems.…”
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Adaptation of the nutrition care process for metabolic diseases in the Mexican population by Magdalena Sevilla-González, Magdalena Sevilla-González, Magdalena Sevilla-González, Ailema González-Ortiz, Ailema González-Ortiz, María Victoria Landa-Anell, Marco A. Melgarejo-Hernández, Marco A. Melgarejo-Hernández, Ana Teresa Arias-Marroquín, Fabiola Mabel Del Razo-Olvera, Fabiola Mabel Del Razo-Olvera, Berenice Monserrat Román-Calleja, Ana Victoria Monreal-Lugo, Angélica J. Martin-Vences, Karime Haua-Navarro, Angeles Espinosa-Cuevas

“…Given the high prevalence of metabolic diseases in Mexican population, there is a critical need for tailored nutrition care strategies.ObjectiveWe aim to describe the adaptation of the NCP to manage metabolic diseases in Mexican individuals.MethodsOur adaptation included a comprehensive literature review of clinical nutrition guidelines, by a structured consultation with experts to ensure clinical setting-specific and culturally appropriate modifications. …”
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Tackling the Problem of Distributional Shifts: Correcting Misspecified, High-dimensional Data-driven Priors for Inverse Problems by Gabriel Missael Barco, Alexandre Adam, Connor Stone, Yashar Hezaveh, Laurence Perreault-Levasseur

“…Bayesian inference for inverse problems hinges critically on the choice of priors. In the absence of specific prior information, population-level distributions can serve as effective priors for parameters of interest. …”
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Nanotherapeutic smart approaches for combating Alzheimer’s disease and overcoming existing obstacles: A novel eco-friendly green approach by Ahmed M. Almehdi, Doha H. Aboubaker, Rania Hamdy, Ali El-Keblawy

“…The scientific community has united to raise awareness of Alzheimer's disease (AD) as a critical condition for future generations because recent predictions indicate that it will become common among the elderly within a few years. …”
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DockCADD: A streamlined in silico pipeline for the identification of potent ribosomal S6 Kinase 2 (RSK2) inhibitors by El Mehdi Karim, Meriem Khedraoui, Abdelkbir Errougui, Yasir S. Raouf, Abdelouahid Samadi, Samir Chtita

“…The search for innovative therapeutic strategies remains critical in addressing cancer, one of the leading global health challenges. …”
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The role of 5G network in revolutionizing agriculture for sustainable development: A comprehensive review by Wasif ur Rehman, Mohsin Ali Koondhar, Samandar Khan Afridi, Lutfi Albasha, Idris H. Smaili, Ezzeddine Touti, Mouloud Aoudia, Wassim Zahrouni, Ibrahim Mahariq, M.M.R. Ahmed

“…The paper identifies critical areas for further research and emphasizes the importance of collaborative efforts among stakeholders to maximize the benefits of 5G-enabled smart farming, thereby contributing to global efforts to achieve SDGs related to food security, innovation in technology, and sustainable infrastructure.…”
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Unveiling the mechanism of micro-and-nano plastic phytotoxicity on terrestrial plants: A comprehensive review of omics approaches by Asad Jamil, Ambreen Ahmad, Muhammad Moeen-ud-din, Yihao Zhang, Yuxuan Zhao, Xiaochen Chen, Xiaoyu Cui, Yindong Tong, Xianhua Liu

“…Furthermore, we have identified critical knowledge gaps and proposed future research directions, highlighting the necessity for integrative omics studies to elucidate the complex pathways of MNPs toxicity in terrestrial plants. …”
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Mast cells: key players in digestive system tumors and their interactions with immune cells by Feihong Shu, Jie Yu, Youjia Liu, Fang Wang, Guoyou Gou, Min Wen, Chen Luo, Xianmin Lu, Yanxia Hu, Qian Du, Jingyu Xu, Rui Xie

“…Abstract Mast cells (MCs) are critical components of both innate and adaptive immune processes. …”
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Autologous Cytokine-Induced Killer Cell Immunotherapy Enhances Chemotherapy Efficacy against Multidrug-Resistant Tuberculosis by Peijun Tang, Xingnian Chen, Junchi Xu, Yunlong Hu, Zhijian Ye, Xiafang Wang, Yumei Xiao, Xinghua Shen, Jianping Zhang, Yanjun Feng, Cuilin Shi, Xin Yu, Lixian Yi, Xinchun Chen, Binfeng Lu, Ping Xu, Zhongwen Sun, Meiying Wu

“…T cell-mediated immunity plays a critical role in controlling Mycobacterium tuberculosis (Mtb) infection, and therefore, enhancing Mtb-specific T cell immune responses represents a promising therapeutic strategy against TB. …”
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Study of Shale Gas Source Rock S-Wave Structure Characteristics via Dense Array Ambient Noise Tomography in Zhangjiakou, China by Si Chen, Zhanwu Lu, Haiyan Wang, Qingyu Wu, Wei Cai, Guowei Wu, Guangwen Wang

“…Utilizing short-period dense seismic arrays, ambient noise tomography has proven effective in delineating continuous geological structures, a task critical for characterizing shale gas reservoir configurations. …”
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Impact of Business Planning for Mini Oil Refineries to Enhance Socio-Economic Landscape by Violetta Roshchupkina, Natalia Dimurina, Viktoriya Manuylenko, Natalia Gryzunova, Elena Drannikova, Mukhamed Khamukov

“… This article develops a comprehensive business plan for establishing a mini-oil refinery in a Russian Federation territory currently lacking refining capacity. Recognizing the critical need for localized oil processing due to a regional monopoly and the high demand for petroleum products, this study aims to provide a strategic blueprint for potential investors and local authorities. …”
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Measurement through structural equations of the self-concept instrument in high-school students by Angel Ramón Sabando-García, Oswaldo José Jiménez-Bustillo, Lidia Janeth Llacsa-Puma, Graciela Josefina Castro-Castillo, Jenniffer Sobeida Moreira-Choez, Raúl Alberto Rengifo-Lozano

“…IntroductionSelf-concept is a fundamental component of psychological and educational development, playing a critical role in students' academic performance and emotional wellbeing. …”
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The implications of the ongoing war on Gaza for food sustainability by Abdo Hassoun, Ahmed Hamad, Dalal Iriqat, Mohammed Nijim, Yamina Bouchikh, Mohamed Buheji, Tahani Z. Aldahdouh

“…These actions are also critical to addressing broader regional and global implications, including threats to food security and trade stability.…”
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Changes in the nutrient composition of top-selling packaged foods and beverages in Colombia between 2016 to 2021 by Luis Carlos Forero, Luis F. Gómez, Mercedes Mora-Plazas, María Parra-Murillo, María Parra-Murillo, Sara Toquica, Lindsey Smith Taillie

“…McNemar’s test for paired data was used to evaluate changes in the proportion of each of the critical nutrients and NNS to be regulated.ResultsThere were no significant changes in sodium, saturated fat, trans fat, or free sugar in foods or beverages prior to policy implementation. …”
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‘With this study, we have hope that something is coming’: community members’ perceptions of HIV cure-related research in Durban, South Africa – a qualitative focus group study... by Karine Dubé, Deli Mthimkhulu, Wiseman Ngcobo, Deborah Mindry, Luyanda Maphalala, Vanessa Pillay, Whitney Tran, Ana Korolkova, Thumbi Ndung’u, Krista Dong

“…Conclusions With HIV cure trials set to launch across Africa in the future, there is a critical need to better understand and respond to local community needs and preferences and to adopt this as standard practice prior to regional trial implementation.…”
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Vibration-Based Damage Prediction in Composite Concrete–Steel Structures Using Finite Elements by Mario D. Cedeño-Rodríguez, Sergio J. Yanez, Erick I. Saavedra-Flores, Carlos Felipe Guzmán, Juan Carlos Pina

“…The prediction of structural damage through vibrational analysis is a critical task in the field of composite structures. …”
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How Interpretable Machine Learning Can Benefit Process Understanding in the Geosciences by Shijie Jiang, Lily‐belle Sweet, Georgios Blougouras, Alexander Brenning, Wantong Li, Markus Reichstein, Joachim Denzler, Wei Shangguan, Guo Yu, Feini Huang, Jakob Zscheischler

“…In particular, we identify several critical and common pitfalls in the use of IML that can lead to misleading conclusions, and propose corresponding good practices. …”
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Silymarin as a Therapeutic Agent for Hepatocellular Carcinoma: A Multi-Approach Computational Study by Ouided Benslama, Sabrina Lekmine, Hamza Moussa, Hichem Tahraoui, Mohammad Shamsul Ola, Jie Zhang, Abdeltif Amrane

“…Molecular docking analysis was conducted on the primary silymarin components against VEGFA and SRC proteins, which are critical in HCC progression. MD simulations followed to assess the stability and interactions of the docked complexes. …”
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