Effect of microstructure and neutron irradiation defects on deuterium retention in SiC by Alex Leide, Weicheng Zhong, Isabel Fernandez-Victorio, Isabel Fernandez-Victorio, Duc Nguyen-Manh, Duc Nguyen-Manh, Takaaki Koyanagi

“…Retention of hydrogen isotopes is a critical concern for operating fusion reactors as retained tritium both activates components and removes scarce fuel from the fuel cycle. …”
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Molecular structures and adsorption of dyes on bismuth oxychloride surfaces using density functional theory and Monte Carlo dynamic simulation by Tadesse Lemma Wakjira, Abebe Belay Gemta, Kumneger Tadele, Gashaw Beyene Kassahun, Umer sherefedin, T. Gurumurthi, Tesfaye Feyisa

“…Quantum theory of atoms in molecules analysis shows three critical points (atom, bond and ring) were observed in each dye. …”
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Post-traumatic arthritis: overview on pathogenic mechanisms and role of inflammation by Roberta Ramonda, Leonardo Punzi, Anna Scanu, Francesca Oliviero, Roberto Luisetto, Paola Galozzi, Marta Favero

“…The activation of inflammatory mechanisms during the PTA acute phase appears to play a critical role in the chronic disease onset. Human studies and experimental models have revealed that a series of inflammatory mediators are released in synovial fluid immediately after the joint trauma. …”
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Nε-carboxyethyl-lysin influences atherosclerotic plaque stability through ZKSCAN3 acetylation-regulated macrophage autophagy via the RAGE/LKB1/AMPK1/SIRT1 pathway by Zhongwei Liu, Jing Liu, Xiqiang Wang, Yong Zhang, Yanpeng Ma, Gongchang Guan, Ya Yuwen, Ni He, Hanxiu Liu, Xingfeng Yu, Sen Ma, Junkui Wang, Jin Zhang, Ling Zhu, Yulian Zhang

“…These findings highlight CEL’s critical role in promoting plaque instability in T2DM by impairing key molecular pathways that regulate autophagy, offering potential therapeutic targets for managing atherosclerosis in diabetic patients.…”
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Geochemical evolution and mechanisms controlling groundwater chemistry in the transboundary Komadugu–Yobe Basin, Lake Chad region: An integrated approach of chemometric analysis an... by Abdulrahman Shuaibu, Robert M. Kalin, Vernon Phoenix, Ibrahim Mohammed Lawal

“…Study region: The study is conducted in the transboundary Komadugu–Yobe Basin, Lake Chad region, a critical groundwater resource shared across national boundaries of Nigeria and Niger Republic. …”
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Computational identification and experimental validation of novel Saccharum officinarum microRNAs along with their targets through RT-PCR approach by Abdul Baqi, Samiullah, Jadoon Khan, Asma Sadiq, Yousaf Khan, Shahid Ali, Syed Nadeem ul Hassan Mohani, Naqeebullah Khan, Tawaf Ali Shah, Khalid S. Almaary, Youssouf Ali Younous, Mohammed Bourhia

“…MicroRNAs (miRNAs) play critical regulatory roles in enhancing yield and providing protection against various stressors. …”
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Biosolids Effects in Chihuahuan Desert Rangelands: A Ten-Year Study by David B. Wester, Ronald E. Sosebee, Richard E. Zartman, Ernest B. Fish, J. Carlos Villalobos, Ricardo Mata-Gonzalez, Pedro Jurado, Corey A. Moffet

“…Topical application is critical to avoid soil and vegetation disturbance. …”
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Advancing Alzheimer's Therapy: Computational strategies and treatment innovations by Jibon Kumar Paul, Abbeha Malik, Mahir Azmal, Tooba Gulzar, Muhammad Talal Rahim Afghan, Omar Faruk Talukder, Samar Shahzadi, Ajit Ghosh

“…Our findings underscore the critical role of computational models in elucidating disease mechanisms, identifying therapeutic targets, and expediting drug discovery. …”
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Availability, accessibility and activation of mental health services among university students in Africa: a protocol of a mixed-methods systematic review with meta-analysis and met... by Hesborn Wao, Melvin A Wao, Ian Muriithi, Paul Seraii, Jackline Syonguvi

“…For cross-sectional studies, we will use the Joanna Briggs Institute Checklist for Analytical Cross Sectional Studies whereas qualitative or mixed-methods studies will be assessed using the Critical Appraisal Skills Programme. OR, risk ratio or mean difference with 95% CI will be considered as the effect size. …”
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Social Justice Work in the University: Understanding Student and Staff Perceptions and Aspirations for Decolonising the Curriculum from a University-Wide Survey by Kyra Araneta, Kelsea Costin, Jennifer Fraser, Fatima Maatwk, Özge Süvari, Esra Tahir

“…This study aims to enrich the discourse on social justice work in higher education by offering a critical lens on decolonial efforts and highlighting opportunities for collective action to rethink knowledge production and pedagogical practices. …”
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Liquid biopsy approaches to capture tumor evolution and clinical outcomes during cancer immunotherapy by Susan Scott, Mark Sausen, Valsamo Anagnostou, Jennifer Jackson, Vincent Lam, Joseph C Murray, Lavanya Sivapalan, Jenna Vanliere Canzoniero, Blair Landon, Benjamin P. Levy

“…The clinical translation of liquid biopsies is propelled by the increasing number of ctDNA-directed interventional clinical trials in the immuno-oncology space, signifying a critical step towards implementation of liquid biopsies in precision immuno-oncology.…”
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Ozone oxidative preconditioning: a protection against cellular damage by free radicals by O. S. León, S. Menéndez, N. Merino, R. Castillo, S. Sam, L. Pérez, E. Cruz, V. Bocci

“…Six groups of rats were classified as follows: (1) negative control, using intraperitoneal sunflower oil; (2) positive control using carbon tetrachloride (CCl4) as an oxidative challenge; (3) oxygen-ozone, pretreatment via rectal insufflation (15 sessions ) and after it, CCl4; (4) oxygen, as group 3 but using oxygen only; (5) control oxygen-ozone, as group 3, but without CCl4 ; group (6) control oxygen, as group 5, but using oxygen only. We have evaluated critical biochemical parameters such as levels of transaminase , cholinesterase , super - oxide dismutase, catalase , phospholipase A, calcium dependent ATPase, reduced glutathione , glucose 6 phosphate dehydrogenase and lipid peroxidation. …”
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Optimization of Well Patterns in Offshore Low-Permeability Thin Interbedded Reservoirs: A Numerical Simulation Study in the Bozhong Oilfield, China by Guangai Wu, Yingwen Ma, Yanfeng Cao, Anshun Zhang, Wei Liu, Jinghe Wang, Xinyi Yang

“…The findings provide critical insights into optimizing well patterns and fracture network designs for offshore low-permeability thin interbedded reservoirs.…”
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Topography of Genetic Loci in Tissue Samples: Towards New Diagnostic Tool Using Interphase FISH and High-Resolution Image Analysis Techniques by I. Koutná, S. Kozubek, J. Žaloudík, M. Kozubek, E. Lukášová, P. A. Matula, E. Bártová, M. Skalníková, A. Cafourková, P. Jirsová

“…In order to validate high‐resolution cytometry for oncology, further investigations should include more precise parameters reflecting the state of chromatin in the neighbourhood of critical oncogenes or tumour suppresser genes.…”
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Immune cell profiles and predictive modeling in osteoporotic vertebral fractures using XGBoost machine learning algorithms by Yi-Chou Chen, Hui-Chen Su, Shih-Ming Huang, Ching-Hsiao Yu, Jen-Huei Chang, Yi-Lin Chiu

“…These findings underscore the critical role of immune cells in the pathogenesis of osteoporotic fractures and highlight the potential of XGBoost in identifying key biomarkers and therapeutic targets for mitigating fracture risk in osteoporotic patients.…”
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Bronchotracheal Stenting Management by Rigid Bronchoscopy under Extracorporeal Membrane Oxygenation (ECMO) Support: 10 Years of Experience in a Tertiary Center by Sabrina Meyer, Anne-Sophie Dincq, Lionel Pirard, Sebahat Ocak, Jean-Paul D’Odémont, Philippe Eucher, Benoît Rondelet, André Gruslin, Laurie Putz

“…Hence, a strategy for maintaining oxygenation and hemodynamic stability should be anticipated to avoid critical situations. Herein, we report the use of extracorporeal membrane oxygenation (ECMO) in bronchotracheal stenting management to secure oxygenation and facilitate interventions. …”
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Microbial Characteristics and Functions in Coffee Fermentation: A Review by Xiaojing Shen, Qi Wang, Hongsheng Wang, Guoqing Fang, Ying Li, Jilai Zhang, Kunyi Liu

“…The first stage of coffee production is obtaining green coffee beans through the primary process. Fermentation is critical in the primary process of coffee, which is often related to yeasts, bacteria, and filamentous fungi. …”
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A systematic review of Aspilia africana (Pers.) C.D. adams traditional medicinal uses, phytoconstituents, bioactivities, and toxicities by Roggers Gang, Denis Okello, Yeongjun Ban, Youngmin Kang

“…This study aimed to systematically and critically compile data on the traditional medicinal uses, phytochemistry, bioactivities, botanical descriptions, and toxicities of A. africana. …”
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Phosphorus Dynamics in Managed and Natural Soils: SEM-PLS Analysis of <i>Vaccinium</i>, Forest, and Grassland Ecosystems by Chun Lu, Soh Sugihara, Satoshi Noma, Haruo Tanaka, Ryosuke Tajima, Shingo Matsumoto, Dai Hirose, Xueyan Zhang, Ning Wang, Takuya Ban

“…These findings underscore the critical importance of prioritizing chemical property management over physical modifications to optimize nutrient cycling, preserve soil fertility, and reduce reliance on external phosphorus inputs in agricultural systems. …”
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The Possible Role of TLR2 in Chronic Hepatitis B Patients with Precore Mutation by Malihe Moradzadeh, Sirous Tayebi, Hossein Poustchi, Kourosh Sayehmiri, Parisa Shahnazari, Elnaz Naderi, Ghodratollah Montazeri, Ashraf Mohamadkhani

“…These findings showed the dominance of G1896A pre-core mutation of HBV variants in this community which was correlated with serum TLR2. Moreover TLR2 is critical for induction of inflammatory cytokines and therefore ALT elevation.…”
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