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12981
Assessment of Protective Effects of Carvacrol on Haloperidol-Induced Oxidative Stress and Genotoxicity in Human Peripheral Blood Lymphocytes
Published 2022-01-01“…It can be presumed that the induction of oxidative stress by haloperidol is the critical event associated with haloperidol-mediated genotoxicity. …”
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12982
Theoretical and Experimental Evaluation of a Compact Aerosol Wind Tunnel and its Application for Performance Investigation of Particulate Matter Instruments
Published 2021-03-01“…First, we computationally analysed the flow quality of different wall shapes for the contraction section, the most critical part of a wind tunnel, and selected the design exhibiting minimal boundary layer separation at simulated flow velocities of 2 and 8 km h−1. …”
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12983
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12984
SERPINA1 mRNA as a Treatment for Alpha-1 Antitrypsin Deficiency
Published 2018-01-01“…In vivo studies in wild type mice demonstrate SERPINA1 mRNA biodistribution in liver and lungs, as well as SerpinA1 protein expression in these two target organs which are critically affected in AAT deficiency. Taken together, our data suggests that SerpinA1 mRNA therapy has the potential to benefit patients suffering from AAT deficiency.…”
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12985
The Role of Aquaculture in Shaping the Morphology of <i>Babylonia areolata</i>: A Comparative Study of Cultured and Wild Populations
Published 2025-01-01“…Background: With the rapid expansion of aquaculture, the impact of rearing environments on the morphological characteristics of marine species has become a critical research focus. This study investigates the morphological differences between wild and cultured populations of <i>B. areolata</i>, a commercially valuable marine mollusk, to understand how aquaculture environments influence morphological traits. …”
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12986
Recent Progress about Flight Delay under Complex Network
Published 2021-01-01“…This may be achieved by analyzing flight delay in frequency domain instead of time domain. (4) Summation of most critical nodes/edges may not be the most crucial group to network resilience or flight delay propagations. …”
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12987
Global Prevalence of Fuchs Endothelial Corneal Dystrophy (FECD) in Adult Population: A Systematic Review and Meta-Analysis
Published 2022-01-01“…Risk of bias assessment was performed using the Joanna Briggs Institute Prevalence Critical Appraisal Tool. Meta-analysis was conducted using R (version 1.4.1106, package “meta”). …”
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12988
Major heavy metals and human gut microbiota composition: a systematic review with nutritional approach
Published 2025-01-01“…Abstract Background The human gut microbiota has a critical role in several aspects of host homeostasis, such as immune development, metabolism, nutrition, and defense against pathogens during life. …”
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12989
Differential Expression of Sphingosine-1-Phosphate Receptors in Abdominal Aortic Aneurysms
Published 2012-01-01“…Newly discovered Sphingosine-1-Phosphate Receptors (S1P receptors) are critical in modulating inflammatory response via prostaglandin production. …”
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12990
Testing convolutional neural network based deep learning systems: a statistical metamorphic approach
Published 2025-01-01“…Machine learning technology spans many areas and today plays a significant role in addressing a wide range of problems in critical domains, i.e., healthcare, autonomous driving, finance, manufacturing, cybersecurity, etc. …”
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12991
The impact of headache specialist density and the introduction of gepants and lasmitidan on prescriptions for acute migraine treatments: a regression and interrupted time series an...
Published 2025-02-01“…Additionally, the introduction of the gepants and lasmiditan broadly decreased the utilization of triptans. Critically, there was a strong association between a pharmaceutical company’s, Pfizer, payments to physicians and utilization of their medication, rimegepant.…”
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12992
Experimental Study of Fracture Characterizations of Rocks under Dynamic Tension Test with Image Processing
Published 2019-01-01“…The experimental results indicate that (1) impact velocity plays a critical role in both crack propagation process and dynamic mechanical properties, (2) the crack fractal dimension is positively correlated with crack propagation velocity and has a linear relationship with the proposed morphological feature of crack, (3) mean strain rate and max strain of rocks under SHPB loading both decrease with the increase of crack propagation velocity, and (4) the energy absorbed by the rocks increases with increasing impact velocity and has a strong negative correlation with a proposed novel crack descriptor. …”
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12993
E3 Ubiquitin Ligase CHIP Inhibits the Interaction between Hsp90β and MAST1 to Repress Radiation Resistance in Non-Small-Cell Lung Cancer Stem Cells
Published 2022-01-01“…The radiation resistance of cancer stem cells poses a critical obstacle for management of non-small-cell lung cancer (NSCLC). …”
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12994
Peran Faktor Persalinan terhadap Stunting pada Balita: Studi di Desa Tasikmadu, Indonesia
Published 2023-10-01“…The implication is that the roots of stunting lie predominantly in postnatal practices, emphasizing the critical role of addressing issues such as inappropriate MP-ASI practices and breastfeeding patterns to effectively combat the prevalence of stunting among toddlers. …”
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12995
Global Perspectives on Laptop Features: A Sentiment Analysis of User Preferences in Developed and Developing Countries
Published 2025-01-01“…Findings show that consumers in developing countries express higher overall satisfaction, while those in developed countries demonstrate more critical views, particularly regarding performance-related features. …”
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12996
Thriving in golden years: Promoting psychological well-being for healthy ageing in India
Published 2025-03-01“…Psychological well-being is a critical factor that contributes to healthy ageing, yet it is often overlooked. …”
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12997
A High-Precision Micro-Roll Forming Facility for Fuel Cell Metal Bipolar Plate Production
Published 2025-01-01“…The metal bipolar plate is a critical component of the hydrogen fuel cell stack used in proton exchange membrane fuel cells. …”
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12998
Investigations on Quasi-Steady Characteristics for an Airfoil Oscillating at Low Reduced Frequencies
Published 2010-01-01“…Static and quasi-steady conditions are critically assessed in context of the existence of laminar separation bubble within the opted Re regime. …”
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12999
Study on a New Method of Link-Based Link Prediction in the Context of Big Data
Published 2021-01-01“…There is a tone of books written on the same; nonetheless, they are core issues that are not always addressed in these studies, which are critical in understanding the concept of link prediction. …”
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13000
Natural killer cell engagers for cancer immunotherapy
Published 2025-01-01“…This review article critically examines the strategies for engineering bi-, tri-, and multi-specific NKCEs for cancer immunotherapy, providing an in-depth analysis of the latest advancements in NKCE platform technologies currently under development by pharmaceutical and biotech companies and discussing the preclinical and clinical progress of these products. …”
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