Formulation and pharmaceutical development of quetiapine fumarate sustained release matrix tablets using a QbD approach by Gavan Alexandru, Porfire Alina, Marina Cristina, Tomuta Ioan

“…For the D-optimal experimental design, the level and ratio of matrix forming agents and the type of extragranular diluent were chosen as independent inputs, which represented critical formulation factors. The critical quality attributes (CQAs) studied were the cumulative percentages of quetiapine released after certain time intervals. …”
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Machine Learning-Based Anomaly Prediction for Proactive Monitoring in Data Centers: A Case Study on INFN-CNAF by Andrea Asperti, Gabriele Raciti, Elisabetta Ronchieri, Daniele Cesini

“…At INFN-CNAF, large volumes of heterogeneous data critical to international experiments are managed using dedicated monitoring systems. …”
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Russian Spatial Development Strategy: blind spots in regional specialisations by N. S. Kozyr

“…The results of the study extend the list of criticisms from the Russian scientific community regarding the indicated document. …”
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Sensory Eye Dominance in Treated Anisometropic Amblyopia by Yao Chen, Jiafeng Wang, Hongmei Shi, Xiaoxiao Wang, Lixia Feng

“…Amblyopia results from inadequate visual experience during the critical period of visual development. Abnormal binocular interactions are believed to play a critical role in amblyopia. …”
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Development and evaluation of the organization`s logistics strategy based on the application of bifurcation theory by M. Yu. Uchirova, L. A. Ilin, S. V. Khudyakov

“…The main concept defining the process of critical transition of the state of the logistic system is the bifurcation point.…”
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Hermenêutica de Profundidade na pesquisa social by Marilia Veríssimo Veronese, Pedrinho Arcides Guareschi

“…Issues about knowledge and investigation in contemporary research practices are discussed, and within this context the use of HP is critically assessed…”
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Integration of Pulsed-Laser ESPI with Spatial Domain Modal Analysis by H. Van der Auweraer, H. Steinbichler, C. Haberstok, R. Freymann, D. Storer

“…The present paper discusses the various critical elements of a modal testing system based on pulsed-laser holographic ESPI measurements. …”
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The situation in Afghanistan and its possible evolution in the context of the "factor 2014" by A. A. Orlov

“…The author considers that critical importance for the future of Afghanistan has its integration into the world economy.…”
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CLUSTER MECHANISM OF METALS CRYSTALLIZATION by N. K. Tolochko, A. A. Andrushevich

“…The regularities of metal crystallization, in particular, the dependence of melt critical overcooling on preliminary overheating conditions are investigated theoretically taking into account modern conception of melt cluster structure. …”
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The evolution of the Orthodox church's mission under the influence of modernization by O. L. Tserpitskaya

“…The basic forms of modern missionary work Russian Orthodox Church, special features in the context of socio-cultural and political situation of the Orthodox believers and groups that exhibit a positive attitude toward the ideals of Orthodoxy. Critical of the Orthodox mission in negative manifestations of postmodernism in culture.…”
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Editorial by Johan M. Strijdom, Lee-Shae S. Scharnick-Udemans

“…Written from an African location by researchers from diverse disciplines, the essays contribute to the debate on critical issues in the intersection between religion, politics, society,and gender. …”
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Multiple Solutions for the Discrete p-Laplacian Boundary Value Problems by Yuhua Long, Haiping Shi

“…By employing a critical point theorem, established by Bonanno, we prove the existence of three distinct solutions to boundary value problems of nonlinear difference equations with a discrete p-Laplacian operator. …”
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In situ simulation for cardiopulmonary resuscitation training: A systematic review by Andrea Cortegiani, Mariachiara Ippolito, Cristian Abelairas-Gómez, Sabine Nabecker, Alexander Olaussen, Kasper G. Lauridsen, Yiqun Lin, Taylor Sawyer, Joyce Yeung, Andrew S. Lockey, Adam Cheng, Robert Greif, Aaron Donoghue, Barbara Farquharson, Chih-Wei Yang, Heike Geduld, Kathryn Eastwood, Kevin Nation, Sebastian Sch naubelt, Tasuku Matsuyama, Ying-Chih Ko, Katherine S. Allen, Tracy Kidd, Jan Breckwoldt, Ming-Ju Hsieh

“…The risk of bias was judged as high or some concerns for RCTs and critical or serious for non-randomised studies. The certainty of evidence was very low for all the evaluated outcomes mainly due to risk of bias, inconsistency and imprecision. …”
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Impact of heteroresistance on treatment outcomes of people with drug-resistant TB by R. Crowder, M. Kato-Maeda, B. Schwem, A. dela Tonga, D.M. Geocaniga-Gaviola, E. Lopez, C.L. Valdez, A.R. Lim, N. Hunat, A.G. Sedusta, C.A. Sacopon, G.A.M. Atienza, E. Bulag, D. Lim, J. Bascuña, K. Shah, R.P. Basillio, C.A. Berger, M.C.D.P. Lopez, S. Sen, C. Allender, M. Folkerts, U. Karaoz, E. Brodie, S. Mitarai, A.M.C. Garfin, M.C. Ama, D.M. Engelthaler, A. Cattamanchi, R. Destura

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Examining the therapeutic potential and side effects of calcium channel blockers in mortality and morbidity of patients with stroke: A systematic review of pre-clinical and clinica... by Sevak Hatamian, Asad Abdi, Fatemeh Sadat Seyedi Asl, Armin Tafazolimoghadam, Arian Tavasol, Seyed Ali Mousavi Nejad, Reza Madadi, Zohre Tajabadi, Mina Dehghani, Najmeh Ahmadpoor, Mobina Fathi, Mohammadreza Hajiesmaeili, Navid Nooraei

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Bullous Type 2 Lepra Reaction: A Rare and Significant Case Report by Hrithik Dakssesh Putta Nagarajan, Balakrishnan Kamaraj, Keerthivasan Selvanathan, Pruthvi Raj Kukunoor, Katta Manichandana, Katta Manideep, Biki Kumar Sah

“…Early recognition and differentiation from other bullous disorders are critical for timely corticosteroid and multidrug therapy initiation to improve patient outcomes.…”
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Innate mechanism or acquired instrument: nature of language as basis for understanding cognitive abilities of human beings by O. V. Gorodovich

“…The article contains a critical review of modern problems of Universal Grammar theory by Noam Chomsky. …”
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Periodic Solutions of Second-Order Differential Inclusions Systems with -Laplacian by Liang Zhang, Peng Zhang

“…. , , by using nonsmooth critical point theory. Our results generalize and improve some theorems in the literature.…”
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Multiplicity of Solutions for Gradient Systems Using Landesman-Lazer Conditions by Edcarlos D. da Silva

“…In all results, we use Variational Methods, Morse Theory and Critical Groups.…”
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Empowering Family Physicians to Impart Proper Inhaler Teaching to Patients with Chronic Obstructive Pulmonary Disease and Asthma by Janice M Leung, Mohit Bhutani, Richard Leigh, Dan Pelletier, Cathy Good, Don D Sin

“…BACKGROUND: Patients with chronic obstructive pulmonary disease (COPD) and asthma depend on inhalers for management, but critical errors committed during inhaler use can limit drug effectiveness. …”
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