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3361
CCR2 signaling regulates anti-chlamydia T cell immune responses in the airway.
Published 2025-02-01“…CCR2, a member of the G protein-coupled receptor (GPCR) superfamily, is widely expressed on monocytes, macrophages, activated T cells, and other cell types, and plays a critical role in coordinating the immune response to various infections. …”
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3362
RECK as a Potential Crucial Molecule for the Targeted Treatment of Sepsis
Published 2025-02-01“…Yuting Qin,1,* Shuanglin Liao,1,* Jianbo Sun,2 Huiyun Ye,1 Jiafu Li,1 Jiahui Pan,1 Junbing He,3 Zhengyuan Xia,4,5 Yiming Shao1,6 1Dongguan Key Laboratory of Sepsis Translational Medicine, The Intensive Care Unit, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, Guangdong, People’s Republic of China; 2Dongguan Key Laboratory of Chronic Inflammatory Diseases, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, Guangdong, People’s Republic of China; 3The Key Laboratory of Organ Dysfunction and Protection Translational Medicine, Jieyang Medical Research Center, Jieyang People’s Hospital, Jieyang, Guangdong, People’s Republic of China; 4Department of Anesthesiology and Perioperative Medicine, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, People’s Republic of China; 5State Key Laboratory of Pharmaceutical Biotechnology, Department of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, People’s Republic of China; 6The Key Laboratory of Sepsis Translational Medicine, Guangdong Medical University, Zhanjiang, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yiming Shao, Dongguan Key Laboratory of Sepsis Translational Medicine, the Intensive Care Unit,The First Dongguan Affiliated Hospital, Guangdong Medical University, Jiaoping Road 42, Tangxia Town, Dongguan, Guangdong Province, 523710, People’s Republic of China, Tel +86 18826690188, Email sym@gdmu.edu.cn Zhengyuan Xia, Department of Anesthesiology and Perioperative Medicine, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, People’s Republic of China, Tel +852-68798794, Email zyxia@hku.hkAbstract: Reversion inducing cysteine rich protein with kazal motifs (RECK), a Kazal motif-containing protein, regulates pro-inflammatory cytokines production, migration of inflammatory cells, vascular endothelial growth factor (VEGF) and Wnt pathways and plays critical roles in septic inflammatory storms and vascular endothelial dysfunction. …”
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3363
Effects of manual osteopathic interventions on psychometric and psychophysiological indicators of anxiety, depression and stress in adults: a systematic review and meta-analysis of...
Published 2025-02-01“…Risk of bias was assessed using the JBI Critical Appraisal Checklist. For meta-analyses, Hedges’ g (with 95% CIs) was calculated from postintervention means and SD. …”
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Ghanaian women’s experience of intimate partner violence (IPV) during group antenatal care: a brief report from a cluster randomised controlled trial
Published 2024-12-01“…However, this study highlights the importance of developing multifaceted approaches to decrease the risk of intimate partner violence among women, especially during the critical times of pregnancy and postpartum. Global health impact for policy and action: Effective global health action and policy must extend beyond educational efforts, incorporating multifaceted strategies that include healthcare provider training, robust community engagement, and legislation aimed at preventing intimate partner violence, with a special focus on safeguarding the well-being of women during pregnancy and the postpartum period.…”
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3366
Comparative efficacy of acupuncture therapies in premature ovarian failure: A systematic review and network meta-analysis
Published 2025-05-01“…The NMA was conducted using R and STATA software based on frequency theory, focusing on overall effectiveness rates and hormone levels. Additionally, we critically reviewed methodological limitations and potential biases in the studies included. …”
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3367
‘That’s Enough’ - Workplace Violence Against Physicians, Pharmacists, and Nurses in Saudi Arabia: A Systematic Review of Prevalence, Causes, and Consequences
Published 2025-02-01“…The quality of included studies was assessed using critical appraisal tools for cross-sectional studies.Results: A total of 42 studies were reviewed using the AXIS tool for cross-sectional studies. …”
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3368
Estimating the impact of school closures on the COVID-19 dynamics in 74 countries: A modelling analysis.
Published 2025-01-01“…<h4>Conclusions</h4>Our analysis revealed nuanced effects of school closures on COVID-19 dynamics, with reductions in COVID-19 impacts in most countries but negative epidemiological effects in a few others. We identified critical mechanisms for consideration in future policy decisions, highlighting the unpredictable nature of emerging variants and potential shifts in infection demographics associated with school closures.…”
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Prevalence of childhood overweight and obesity in Malaysia: a systematic review and meta-analysis
Published 2025-02-01“…Variability was not significantly affected by the critical appraisal score or sample size. In conclusion, the prevalence of childhood overweight, obesity, and excess weight in Malaysia doubled over 26 years. …”
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3370
Nanoparticle-mediated gene delivery techniques in plant systems
Published 2025-02-01“…However, delivering the nanoparticles and cargo complexes into plants is a critical step of the gene delivery process, and have not been thoroughly explored. …”
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A Pilot Study Assessing Left Ventricle Diastolic Function in the Parasternal Long-axis View
Published 2024-11-01“…All patients who presented to the emergency critical care unit with symptoms of heart failure were evaluated by the cardiology department, had grade 1 diastolic dysfunction confirmed by the cardiology department, and did not meet any of the study’s exclusion criteria. …”
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3373
Community perceptions of community health worker effectiveness: Contributions to health behaviour change in an urban health district in South Africa
Published 2024-02-01“…As important stakeholders in CHW programmes, exploring community acceptance, appreciation and support is critical in understanding the drivers of programme performance. …”
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HACE1 protects against myocardial ischemia–reperfusion injury via inhibition of mitochondrial fission in mice
Published 2025-02-01“…Mitochondrial damage is a critical contributor to myocardial ischemia–reperfusion injury (I/RI). …”
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3375
The use of Geographic Information Systems as innovative tools for sustainable development strategies and enhancing the efficiency of forest sector entities
Published 2024-10-01“…It was found that the use of Sentinel-2 and Landsat satellite data combined with NDVI and EVI indices in GIS systems allows for identifving critical biodiversity zones and making timely management decisions regarding the conservation and restoration of natural resources in these areas. …”
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Bloodstream infections at a tertiary hospital in the Gambia - a one-year retrospective study
Published 2025-02-01“…Conclusion Overall, blood culture positivity rates were high, indicating restrictive testing suggesting that sample collection were restricted to mainly critically ill, neonatal or paediatric patients. Nonetheless, our data suggests a high proportion of bloodstream infections due to multi-drug resistant pathogens, including MRSA and ESBL-Enterobacterales. …”
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Association between red cell distribution width to albumin ratio and all-cause mortality in patients with acute pancreatitis admitted to the intensive care unit: a retrospective st...
Published 2025-02-01“…Therefore, this study aims to evaluate the relationship between RAR and all-cause mortality in AP.MethodPatients with AP in the Critical Care Medical Information Market (MIMIC-IV) database who met criteria were included in this retrospective study. …”
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3378
Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Published 2022-08-01“…Risk of bias: It was assessed using standardised critical appraisal instruments from the Joanna Briggs Institute for RCTs. …”
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3379
Barriers and enablers to implementing clinical practice guidelines in primary care: an overview of systematic reviews
Published 2023-01-01“…The methodological quality of the included studies was appraised by using the JBI Critical Appraisal Checklist for Systematic Reviews and Research Syntheses. …”
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3380
Militancia, destrucción y resistencias de las mujeres en la Unión Patriótica
Published 2024-08-01“…Abstract This article proposes a brief overview —with a critical analysis— of the history of women in the Unión Patriótica. …”
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